BLASTX 7.6.2
Query= UN77622 /QuerySize=654
(653 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54UJ0|PSD12_DICDI 26S proteasome non-ATPase regulatory subun... 141 5e-033
sp|Q2KJ25|PSD12_BOVIN 26S proteasome non-ATPase regulatory subun... 137 7e-032
sp|O00232|PSD12_HUMAN 26S proteasome non-ATPase regulatory subun... 137 7e-032
sp|Q5RBI3|PSD12_PONAB 26S proteasome non-ATPase regulatory subun... 137 7e-032
sp|Q9D8W5|PSD12_MOUSE 26S proteasome non-ATPase regulatory subun... 136 2e-031
sp|Q9UTM3|RPN5_SCHPO 26S proteasome regulatory subunit rpn5 OS=S... 121 5e-027
sp|Q12250|RPN5_YEAST 26S proteasome regulatory subunit RPN5 OS=S... 114 6e-025
>sp|Q54UJ0|PSD12_DICDI 26S proteasome non-ATPase regulatory subunit 12
OS=Dictyostelium discoideum GN=psmD12 PE=2 SV=1
Length = 447
Score = 141 bits (354), Expect = 5e-033
Identities = 66/157 (42%), Positives = 108/157 (68%), Gaps = 3/157 (1%)
Frame = +1
Query: 181 LLRFCSSVSKPRIGNFSMSRFSTSRRSVGQLKQAVQSMVQQAMQYIDQTPDIETRIELIK 360
+++ C + + N + S R GQL+ A++++VQ++M Y+DQ D++ ++ELI
Sbjct: 71 IIKLCYEAGRLDLVNEKLVLLSKRR---GQLRPAIKAIVQESMVYVDQITDMKQKLELID 127
Query: 361 TLNNVSAGKIYVEIERARLTRKLAKIKEDQGQIAGAADLMQEVAVETFGAMAKTEKIAFI 540
TL +S GKI+VE ERARLT+ L+KIKED+G IA AA ++Q++ VET+G M K EKI F
Sbjct: 128 TLRTISDGKIFVENERARLTKTLSKIKEDEGDIASAAKILQDLQVETYGTMEKREKITFF 187
Query: 541 LEQVRLCLDRQDYVRAQILSRKINPRVFDADTKKDKK 651
++Q+R+C++ +D++RAQ++ K+N + D +D K
Sbjct: 188 IDQMRICMNNKDFIRAQLIGNKVNRKTLAEDENQDLK 224
>sp|Q2KJ25|PSD12_BOVIN 26S proteasome non-ATPase regulatory subunit 12 OS=Bos
taurus GN=PSMD12 PE=2 SV=3
Length = 456
Score = 137 bits (344), Expect = 7e-032
Identities = 70/135 (51%), Positives = 95/135 (70%), Gaps = 2/135 (1%)
Frame = +1
Query: 247 TSRRSVGQLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRK 426
+ RRS QLKQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+
Sbjct: 91 SKRRS--QLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKT 148
Query: 427 LAKIKEDQGQIAGAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRK 606
LA IKE G + AA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+K
Sbjct: 149 LATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKK 208
Query: 607 INPRVFDADTKKDKK 651
IN + F + + K
Sbjct: 209 INTKFFQEENTEKLK 223
>sp|O00232|PSD12_HUMAN 26S proteasome non-ATPase regulatory subunit 12 OS=Homo
sapiens GN=PSMD12 PE=1 SV=3
Length = 456
Score = 137 bits (344), Expect = 7e-032
Identities = 70/135 (51%), Positives = 95/135 (70%), Gaps = 2/135 (1%)
Frame = +1
Query: 247 TSRRSVGQLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRK 426
+ RRS QLKQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+
Sbjct: 91 SKRRS--QLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKT 148
Query: 427 LAKIKEDQGQIAGAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRK 606
LA IKE G + AA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+K
Sbjct: 149 LATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKK 208
Query: 607 INPRVFDADTKKDKK 651
IN + F + + K
Sbjct: 209 INTKFFQEENTEKLK 223
>sp|Q5RBI3|PSD12_PONAB 26S proteasome non-ATPase regulatory subunit 12 OS=Pongo
abelii GN=PSMD12 PE=2 SV=3
Length = 456
Score = 137 bits (344), Expect = 7e-032
Identities = 70/135 (51%), Positives = 95/135 (70%), Gaps = 2/135 (1%)
Frame = +1
Query: 247 TSRRSVGQLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRK 426
+ RRS QLKQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+
Sbjct: 91 SKRRS--QLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKT 148
Query: 427 LAKIKEDQGQIAGAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRK 606
LA IKE G + AA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+K
Sbjct: 149 LATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKK 208
Query: 607 INPRVFDADTKKDKK 651
IN + F + + K
Sbjct: 209 INTKFFQEENTEKLK 223
>sp|Q9D8W5|PSD12_MOUSE 26S proteasome non-ATPase regulatory subunit 12 OS=Mus
musculus GN=Psmd12 PE=2 SV=3
Length = 456
Score = 136 bits (340), Expect = 2e-031
Identities = 69/135 (51%), Positives = 95/135 (70%), Gaps = 2/135 (1%)
Frame = +1
Query: 247 TSRRSVGQLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRK 426
+ RRS QLKQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+
Sbjct: 91 SKRRS--QLKQAVAKMVQQCCTYVEEITDLPVKLRLIDTLRMVTEGKIYVEIERARLTKT 148
Query: 427 LAKIKEDQGQIAGAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRK 606
LA IKE G + AA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+K
Sbjct: 149 LATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKK 208
Query: 607 INPRVFDADTKKDKK 651
IN + + ++ K
Sbjct: 209 INTKFSQEENTENMK 223
>sp|Q9UTM3|RPN5_SCHPO 26S proteasome regulatory subunit rpn5
OS=Schizosaccharomyces pombe GN=rpn5a PE=1 SV=1
Length = 443
Score = 121 bits (302), Expect = 5e-027
Identities = 61/129 (47%), Positives = 89/129 (68%)
Frame = +1
Query: 265 GQLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKE 444
GQLKQ++ S+VQ M Y+ D++T+I LI+TL ++ GKIYVE+ERARLT+ L++IKE
Sbjct: 83 GQLKQSMTSLVQHVMTYLPGIDDLKTKINLIETLRTITDGKIYVEVERARLTQLLSQIKE 142
Query: 445 DQGQIAGAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINPRVF 624
+QG I A +++ VET+G+ EK+AFIL+QVRL L R DY A ++KIN + F
Sbjct: 143 EQGDIKSAQEILCNEPVETYGSFDLKEKVAFILDQVRLFLLRSDYYMASTYTKKINVKFF 202
Query: 625 DADTKKDKK 651
+ + + K
Sbjct: 203 EKEDVQSLK 211
>sp|Q12250|RPN5_YEAST 26S proteasome regulatory subunit RPN5 OS=Saccharomyces
cerevisiae GN=RPN5 PE=1 SV=3
Length = 445
Score = 114 bits (284), Expect = 6e-025
Identities = 57/122 (46%), Positives = 91/122 (74%), Gaps = 2/122 (1%)
Frame = +1
Query: 265 GQLKQAVQSMVQQAMQYI--DQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKI 438
GQLK ++Q M+Q+ M+Y+ ++ D+ TRI +I+T+ V+ KI+VE+ERAR+T+ L +I
Sbjct: 87 GQLKLSIQYMIQKVMEYLKSSKSLDLNTRISVIETIRVVTENKIFVEVERARVTKDLVEI 146
Query: 439 KEDQGQIAGAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINPR 618
K+++G+I AAD++ E+ VET+G+M +EKI FILEQ+ L + + DY +A +LSRKI +
Sbjct: 147 KKEEGKIDEAADILCELQVETYGSMEMSEKIQFILEQMELSILKGDYSQATVLSRKILKK 206
Query: 619 VF 624
F
Sbjct: 207 TF 208
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 249,981,154,389
Number of Sequences: 518415
Number of Extensions: 249981154389
Number of Successful Extensions: 1620631332
Number of sequences better than 0.0: 0
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