BLASTX 7.6.2
Query= UN78318 /QuerySize=746
(745 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P84173|PHB_CHICK Prohibitin OS=Gallus gallus GN=PHB PE=1 SV=1 122 4e-027
sp|Q54GI9|PHB1_DICDI Prohibitin-1, mitochondrial OS=Dictyosteliu... 121 7e-027
sp|Q9P7H3|PHB1_SCHPO Prohibitin-1 OS=Schizosaccharomyces pombe G... 120 1e-026
sp|Q3T165|PHB_BOVIN Prohibitin OS=Bos taurus GN=PHB PE=2 SV=1 119 2e-026
sp|P35232|PHB_HUMAN Prohibitin OS=Homo sapiens GN=PHB PE=1 SV=1 119 2e-026
sp|Q9BKU4|PHB1_CAEEL Mitochondrial prohibitin complex protein 1 ... 119 2e-026
sp|P40961|PHB1_YEAST Prohibitin-1 OS=Saccharomyces cerevisiae GN... 118 4e-026
sp|P67778|PHB_MOUSE Prohibitin OS=Mus musculus GN=Phb PE=1 SV=1 118 4e-026
sp|P67779|PHB_RAT Prohibitin OS=Rattus norvegicus GN=Phb PE=1 SV=1 118 4e-026
sp|P24156|L2CC_DROME Protein l(2)37Cc OS=Drosophila melanogaster... 117 9e-026
sp|P50085|PHB2_YEAST Prohibitin-2 OS=Saccharomyces cerevisiae GN... 109 3e-023
sp|Q54Q31|PHB2_DICDI Prohibitin-2 OS=Dictyostelium discoideum GN... 108 6e-023
sp|O94550|PHB2_SCHPO Prohibitin-2 OS=Schizosaccharomyces pombe G... 99 3e-020
sp|Q99623|PHB2_HUMAN Prohibitin-2 OS=Homo sapiens GN=PHB2 PE=1 SV=2 98 5e-020
sp|O35129|PHB2_MOUSE Prohibitin-2 OS=Mus musculus GN=Phb2 PE=1 SV=1 98 5e-020
sp|Q5RB19|PHB2_PONAB Prohibitin-2 OS=Pongo abelii GN=PHB2 PE=2 SV=1 98 5e-020
sp|Q5XIH7|PHB2_RAT Prohibitin-2 OS=Rattus norvegicus GN=Phb2 PE=... 98 5e-020
sp|P50093|PHB2_CAEEL Mitochondrial prohibitin complex protein 2 ... 93 2e-018
>sp|P84173|PHB_CHICK Prohibitin OS=Gallus gallus GN=PHB PE=1 SV=1
Length = 272
Score = 122 bits (304), Expect = 4e-027
Identities = 58/112 (51%), Positives = 78/112 (69%)
Frame = +1
Query: 100 AVSFLTNLAKAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPIL 279
A ++ K GL V+ V++S+LY VD G RAV+FDRFRGV D VGEGTHFLIP +
Sbjct: 2 AAKVFESIGKFGLGLAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDTVVGEGTHFLIPWV 61
Query: 280 QRPHIFDIRTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCGDE 435
Q+P IFD R++P ++G+KDLQ VN+TLR+L RP ++LP IF G++
Sbjct: 62 QKPIIFDCRSRPRNIPVITGSKDLQNVNITLRILFRPVTAQLPRIFTSIGED 113
Score = 87 bits (214), Expect = 1e-016
Identities = 41/75 (54%), Positives = 62/75 (82%)
Frame = +2
Query: 416 SKFVVMKADQERRAAVIRAEGESEAAQLISDATAKAGMGLIELRRIEASREVAATLARSP 595
++F+V KA+Q+++AAVI AEG+S+AA+LI+++ A AG GLIELR++EA+ ++A L+RS
Sbjct: 196 ARFIVEKAEQQKKAAVISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSR 255
Query: 596 NVAYLPGGQSMLFNL 640
N+ YLP GQS+L L
Sbjct: 256 NITYLPSGQSVLLQL 270
>sp|Q54GI9|PHB1_DICDI Prohibitin-1, mitochondrial OS=Dictyostelium discoideum
GN=phbA PE=3 SV=1
Length = 271
Score = 121 bits (302), Expect = 7e-027
Identities = 58/108 (53%), Positives = 78/108 (72%)
Frame = +1
Query: 106 SFLTNLAKAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPILQR 285
SFL L A +G ++ SS+YTVDGG+RAV+FDR GV +++VGEGTHF++P LQ+
Sbjct: 3 SFLNKLIPLALTVGTGLSLAQSSMYTVDGGQRAVIFDRISGVKEKSVGEGTHFIMPWLQK 62
Query: 286 PHIFDIRTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCG 429
P IFDIR+ P S +G+KDLQ V++T+RVL RP+V LP+IF G
Sbjct: 63 PIIFDIRSSPRNIKSDTGSKDLQTVSVTVRVLFRPDVEHLPSIFSKLG 110
>sp|Q9P7H3|PHB1_SCHPO Prohibitin-1 OS=Schizosaccharomyces pombe GN=phb1 PE=2
SV=1
Length = 282
Score = 120 bits (300), Expect = 1e-026
Identities = 59/106 (55%), Positives = 77/106 (72%)
Frame = +1
Query: 112 LTNLAKAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPILQRPH 291
L +A+ A +G+ T+L SS+Y V GG+RAVLFDR GV Q V EGTHFLIP LQ+
Sbjct: 5 LERVARYAIPIGIGFTLLQSSIYDVPGGKRAVLFDRLSGVQKQVVQEGTHFLIPWLQKAI 64
Query: 292 IFDIRTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCG 429
++D+RT+P ++ +G+KDLQMV+LTLRVL RPEV LP I+Q G
Sbjct: 65 VYDVRTRPRNIATTTGSKDLQMVSLTLRVLHRPEVGMLPQIYQNLG 110
>sp|Q3T165|PHB_BOVIN Prohibitin OS=Bos taurus GN=PHB PE=2 SV=1
Length = 272
Score = 119 bits (298), Expect = 2e-026
Identities = 58/112 (51%), Positives = 77/112 (68%)
Frame = +1
Query: 100 AVSFLTNLAKAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPIL 279
A ++ K L V+ V++S+LY VD G RAV+FDRFRGV D VGEGTHFLIP +
Sbjct: 2 AAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWV 61
Query: 280 QRPHIFDIRTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCGDE 435
Q+P IFD R++P ++G+KDLQ VN+TLR+L RP S+LP IF G++
Sbjct: 62 QKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGED 113
Score = 87 bits (214), Expect = 1e-016
Identities = 41/75 (54%), Positives = 62/75 (82%)
Frame = +2
Query: 416 SKFVVMKADQERRAAVIRAEGESEAAQLISDATAKAGMGLIELRRIEASREVAATLARSP 595
++FVV KA+Q+++AA+I AEG+S+AA+LI+++ A AG GLIELR++EA+ ++A L+RS
Sbjct: 196 ARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSR 255
Query: 596 NVAYLPGGQSMLFNL 640
N+ YLP GQS+L L
Sbjct: 256 NITYLPAGQSVLLQL 270
>sp|P35232|PHB_HUMAN Prohibitin OS=Homo sapiens GN=PHB PE=1 SV=1
Length = 272
Score = 119 bits (298), Expect = 2e-026
Identities = 58/112 (51%), Positives = 77/112 (68%)
Frame = +1
Query: 100 AVSFLTNLAKAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPIL 279
A ++ K L V+ V++S+LY VD G RAV+FDRFRGV D VGEGTHFLIP +
Sbjct: 2 AAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWV 61
Query: 280 QRPHIFDIRTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCGDE 435
Q+P IFD R++P ++G+KDLQ VN+TLR+L RP S+LP IF G++
Sbjct: 62 QKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGED 113
>sp|Q9BKU4|PHB1_CAEEL Mitochondrial prohibitin complex protein 1
OS=Caenorhabditis elegans GN=phb-1 PE=1 SV=1
Length = 275
Score = 119 bits (297), Expect = 2e-026
Identities = 55/107 (51%), Positives = 76/107 (71%)
Frame = +1
Query: 97 AAVSFLTNLAKAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPI 276
+A L L GL ++ + ++LY VDGG+RAV+FDRF GV ++ VGEGTHFLIP
Sbjct: 4 SAQKLLGRLGTVGVGLSIAGGIAQTALYNVDGGQRAVIFDRFSGVKNEVVGEGTHFLIPW 63
Query: 277 LQRPHIFDIRTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIF 417
+Q+P IFDIR+ P ++++G+KDLQ VN+TLR+L RP RLP I+
Sbjct: 64 VQKPIIFDIRSTPRAVTTITGSKDLQNVNITLRILHRPSPDRLPNIY 110
>sp|P40961|PHB1_YEAST Prohibitin-1 OS=Saccharomyces cerevisiae GN=PHB1 PE=1
SV=2
Length = 287
Score = 118 bits (295), Expect = 4e-026
Identities = 57/103 (55%), Positives = 75/103 (72%)
Frame = +1
Query: 121 LAKAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPILQRPHIFD 300
+ K A +G+ A+ + S+Y V GG R V+FDR GV Q VGEGTHFL+P LQ+ I+D
Sbjct: 11 ITKVALPIGIIASGIQYSMYDVKGGSRGVIFDRINGVKQQVVGEGTHFLVPWLQKAIIYD 70
Query: 301 IRTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCG 429
+RTKP + ++ +GTKDLQMV+LTLRVL RPEV +LP I+Q G
Sbjct: 71 VRTKPKSIATNTGTKDLQMVSLTLRVLHRPEVLQLPAIYQNLG 113
>sp|P67778|PHB_MOUSE Prohibitin OS=Mus musculus GN=Phb PE=1 SV=1
Length = 272
Score = 118 bits (295), Expect = 4e-026
Identities = 57/112 (50%), Positives = 77/112 (68%)
Frame = +1
Query: 100 AVSFLTNLAKAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPIL 279
A ++ K L V+ V++S+LY VD G RAV+FDRFRGV D VGEGTHFLIP +
Sbjct: 2 AAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWV 61
Query: 280 QRPHIFDIRTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCGDE 435
Q+P IFD R++P ++G+KDLQ VN+TLR+L RP S+LP I+ G++
Sbjct: 62 QKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGED 113
>sp|P67779|PHB_RAT Prohibitin OS=Rattus norvegicus GN=Phb PE=1 SV=1
Length = 272
Score = 118 bits (295), Expect = 4e-026
Identities = 57/112 (50%), Positives = 77/112 (68%)
Frame = +1
Query: 100 AVSFLTNLAKAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPIL 279
A ++ K L V+ V++S+LY VD G RAV+FDRFRGV D VGEGTHFLIP +
Sbjct: 2 AAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWV 61
Query: 280 QRPHIFDIRTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCGDE 435
Q+P IFD R++P ++G+KDLQ VN+TLR+L RP S+LP I+ G++
Sbjct: 62 QKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGED 113
>sp|P24156|L2CC_DROME Protein l(2)37Cc OS=Drosophila melanogaster GN=l(2)37Cc
PE=1 SV=2
Length = 276
Score = 117 bits (292), Expect = 9e-026
Identities = 54/112 (48%), Positives = 76/112 (67%)
Frame = +1
Query: 100 AVSFLTNLAKAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPIL 279
A F + + G+ V V++S+LY V+GG RAV+FDRF G+ + VGEGTHF IP +
Sbjct: 2 AAQFFNRIGQMGLGVAVLGGVVNSALYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWV 61
Query: 280 QRPHIFDIRTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCGDE 435
QRP IFDIR++P ++G+KDLQ VN+TLR+L RP +LP I+ + G +
Sbjct: 62 QRPIIFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQD 113
>sp|P50085|PHB2_YEAST Prohibitin-2 OS=Saccharomyces cerevisiae GN=PHB2 PE=1
SV=2
Length = 310
Score = 109 bits (270), Expect = 3e-023
Identities = 49/98 (50%), Positives = 70/98 (71%)
Frame = +1
Query: 142 LGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPILQRPHIFDIRTKPHT 321
LG A ++++L+ VDGG RA+++ R GV + EGTHF+ P L P I+D+R KP
Sbjct: 47 LGGGALFINNALFNVDGGHRAIVYSRIHGVSSRIFNEGTHFIFPWLDTPIIYDVRAKPRN 106
Query: 322 FSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCGDE 435
+S++GTKDLQMVN+T RVLSRP+V +LPTI++ G +
Sbjct: 107 VASLTGTKDLQMVNITCRVLSRPDVVQLPTIYRTLGQD 144
>sp|Q54Q31|PHB2_DICDI Prohibitin-2 OS=Dictyostelium discoideum GN=phbB PE=3
SV=1
Length = 293
Score = 108 bits (268), Expect = 6e-023
Identities = 48/98 (48%), Positives = 73/98 (74%)
Frame = +1
Query: 142 LGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPILQRPHIFDIRTKPHT 321
LG + SSL V+GG RA++F+RF G+ ++ EGTHF++P +R I+D+R KP +
Sbjct: 30 LGGVGLLALSSLVNVEGGHRAIVFNRFVGIKNKVYNEGTHFIVPWFERAEIYDVRAKPRS 89
Query: 322 FSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCGDE 435
SS++G+KDLQMVN+T+RVLS+P+VS+LP I++ G +
Sbjct: 90 ISSLTGSKDLQMVNITIRVLSKPKVSQLPAIYRTLGKD 127
>sp|O94550|PHB2_SCHPO Prohibitin-2 OS=Schizosaccharomyces pombe GN=phb2 PE=2
SV=1
Length = 279
Score = 99 bits (244), Expect = 3e-020
Identities = 46/98 (46%), Positives = 66/98 (67%)
Frame = +1
Query: 142 LGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPILQRPHIFDIRTKPHT 321
LG++ + +SL+ VDGG RA+ + R G+ + EGTHFLIP ++ +D+R KP
Sbjct: 25 LGLAGFAVQTSLFNVDGGHRAIKYSRIGGIKNLIYPEGTHFLIPWIETAIDYDVRAKPRN 84
Query: 322 FSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCGDE 435
SS++GTKDLQMVN+ RVLSRP+V LP I++ G +
Sbjct: 85 ISSLTGTKDLQMVNINCRVLSRPDVHALPKIYRTLGGD 122
>sp|Q99623|PHB2_HUMAN Prohibitin-2 OS=Homo sapiens GN=PHB2 PE=1 SV=2
Length = 299
Score = 98 bits (243), Expect = 5e-020
Identities = 50/102 (49%), Positives = 66/102 (64%), Gaps = 1/102 (0%)
Frame = +1
Query: 127 KAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTV-GEGTHFLIPILQRPHIFDI 303
K G G A + S++TV+GG RA+ F+R GV T+ EG HF IP Q P I+DI
Sbjct: 24 KLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDI 83
Query: 304 RTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCG 429
R +P SS +G+KDLQMVN++LRVLSRP LP+++Q G
Sbjct: 84 RARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLG 125
>sp|O35129|PHB2_MOUSE Prohibitin-2 OS=Mus musculus GN=Phb2 PE=1 SV=1
Length = 299
Score = 98 bits (243), Expect = 5e-020
Identities = 50/102 (49%), Positives = 66/102 (64%), Gaps = 1/102 (0%)
Frame = +1
Query: 127 KAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTV-GEGTHFLIPILQRPHIFDI 303
K G G A + S++TV+GG RA+ F+R GV T+ EG HF IP Q P I+DI
Sbjct: 24 KLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDI 83
Query: 304 RTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCG 429
R +P SS +G+KDLQMVN++LRVLSRP LP+++Q G
Sbjct: 84 RARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLG 125
>sp|Q5RB19|PHB2_PONAB Prohibitin-2 OS=Pongo abelii GN=PHB2 PE=2 SV=1
Length = 299
Score = 98 bits (243), Expect = 5e-020
Identities = 50/102 (49%), Positives = 66/102 (64%), Gaps = 1/102 (0%)
Frame = +1
Query: 127 KAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTV-GEGTHFLIPILQRPHIFDI 303
K G G A + S++TV+GG RA+ F+R GV T+ EG HF IP Q P I+DI
Sbjct: 24 KLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDI 83
Query: 304 RTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCG 429
R +P SS +G+KDLQMVN++LRVLSRP LP+++Q G
Sbjct: 84 RARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLG 125
>sp|Q5XIH7|PHB2_RAT Prohibitin-2 OS=Rattus norvegicus GN=Phb2 PE=1 SV=1
Length = 299
Score = 98 bits (243), Expect = 5e-020
Identities = 50/102 (49%), Positives = 66/102 (64%), Gaps = 1/102 (0%)
Frame = +1
Query: 127 KAAFGLGVSATVLSSSLYTVDGGERAVLFDRFRGVLDQTV-GEGTHFLIPILQRPHIFDI 303
K G G A + S++TV+GG RA+ F+R GV T+ EG HF IP Q P I+DI
Sbjct: 24 KLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDI 83
Query: 304 RTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQVCG 429
R +P SS +G+KDLQMVN++LRVLSRP LP+++Q G
Sbjct: 84 RARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLG 125
>sp|P50093|PHB2_CAEEL Mitochondrial prohibitin complex protein 2
OS=Caenorhabditis elegans GN=phb-2 PE=1 SV=2
Length = 294
Score = 93 bits (229), Expect = 2e-018
Identities = 50/123 (40%), Positives = 71/123 (57%), Gaps = 6/123 (4%)
Frame = +1
Query: 79 SKMGSQAAVSFLTNLAKAAFGLGVSATV------LSSSLYTVDGGERAVLFDRFRGVLDQ 240
+K G +A + N A GLG+ A ++ S++TV+ G RA++F+R G+
Sbjct: 2 AKQGQEAMKKAIQNARGAGVGLGLVAAAGAAVYGVAQSMFTVEAGHRAIMFNRIGGLSTD 61
Query: 241 TVGEGTHFLIPILQRPHIFDIRTKPHTFSSVSGTKDLQMVNLTLRVLSRPEVSRLPTIFQ 420
EG HF IP Q P I+DIR +P+ S +G+KDLQMVN+ LRVLSRP L I++
Sbjct: 62 LYKEGLHFRIPWFQYPIIYDIRARPNQIRSPTGSKDLQMVNIGLRVLSRPNPEHLVHIYR 121
Query: 421 VCG 429
G
Sbjct: 122 TLG 124
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 253,397,043,485
Number of Sequences: 518415
Number of Extensions: 253397043485
Number of Successful Extensions: 1641427459
Number of sequences better than 0.0: 0
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