BLASTX 7.6.2
Query= UN78464 /QuerySize=767
(766 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q96SB4|SRPK1_HUMAN Serine/threonine-protein kinase SRPK1 OS=H... 112 2e-024
sp|Q5RD27|SRPK1_PONAB Serine/threonine-protein kinase SRPK1 OS=P... 112 2e-024
sp|O70551|SRPK1_MOUSE Serine/threonine-protein kinase SRPK1 OS=M... 111 5e-024
sp|P78362|SRPK2_HUMAN Serine/threonine-protein kinase SRPK2 OS=H... 111 9e-024
sp|O54781|SRPK2_MOUSE Serine/threonine-protein kinase SRPK2 OS=M... 111 9e-024
sp|Q9UPE1|SRPK3_HUMAN Serine/threonine-protein kinase SRPK3 OS=H... 110 1e-023
sp|Q9Z0G2|SRPK3_MOUSE Serine/threonine-protein kinase SRPK3 OS=M... 110 1e-023
sp|Q61IS6|SPK1_CAEBR Serine/threonine-protein kinase spk-1 OS=Ca... 108 6e-023
sp|Q03563|SPK1_CAEEL Serine/threonine-protein kinase spk-1 OS=Ca... 108 6e-023
sp|P36616|DSK1_SCHPO Protein kinase dsk1 OS=Schizosaccharomyces ... 106 2e-022
sp|Q86A12|SKY1_DICDI Probable serine/threonine-protein kinase sk... 96 2e-019
sp|Q03656|SKY1_YEAST Serine/threonine-protein kinase SKY1 OS=Sac... 91 6e-018
sp|O43781|DYRK3_HUMAN Dual specificity tyrosine-phosphorylation-... 75 3e-013
sp|Q4R6S5|DYRK3_MACFA Dual specificity tyrosine-phosphorylation-... 75 3e-013
sp|Q5UQ24|YL205_MIMIV Putative serine/threonine-protein kinase L... 72 4e-012
sp|P51568|AFC3_ARATH Serine/threonine-protein kinase AFC3 OS=Ara... 69 3e-011
sp|Q9V3D5|DYRK2_DROME Dual specificity tyrosine-phosphorylation-... 68 7e-011
sp|Q54BC9|DYRK2_DICDI Probable serine/threonine-protein kinase d... 67 9e-011
sp|P83102|DYRK3_DROME Putative dual specificity tyrosine-phospho... 66 2e-010
sp|Q9NR20|DYRK4_HUMAN Dual specificity tyrosine-phosphorylation-... 66 2e-010
>sp|Q96SB4|SRPK1_HUMAN Serine/threonine-protein kinase SRPK1 OS=Homo sapiens
GN=SRPK1 PE=1 SV=2
Length = 655
Score = 112 bits (280), Expect = 2e-024
Identities = 48/80 (60%), Positives = 62/80 (77%)
Frame = +1
Query: 25 LKCKLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVL 204
LK K+ D GNACW ++ FT DIQTRQYR EV++GS Y+T AD+WS AC+ FELATGD L
Sbjct: 491 LKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYL 550
Query: 205 FDPHSGDNYDRDEVCVRMLL 264
F+PHSG+ Y RDE + +++
Sbjct: 551 FEPHSGEEYTRDEDHIALII 570
>sp|Q5RD27|SRPK1_PONAB Serine/threonine-protein kinase SRPK1 OS=Pongo abelii
GN=SRPK1 PE=2 SV=2
Length = 655
Score = 112 bits (280), Expect = 2e-024
Identities = 48/80 (60%), Positives = 62/80 (77%)
Frame = +1
Query: 25 LKCKLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVL 204
LK K+ D GNACW ++ FT DIQTRQYR EV++GS Y+T AD+WS AC+ FELATGD L
Sbjct: 491 LKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYL 550
Query: 205 FDPHSGDNYDRDEVCVRMLL 264
F+PHSG+ Y RDE + +++
Sbjct: 551 FEPHSGEEYTRDEDHIALII 570
>sp|O70551|SRPK1_MOUSE Serine/threonine-protein kinase SRPK1 OS=Mus musculus
GN=Srpk1 PE=1 SV=2
Length = 648
Score = 111 bits (277), Expect = 5e-024
Identities = 47/80 (58%), Positives = 63/80 (78%)
Frame = +1
Query: 25 LKCKLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVL 204
L+ K+ D GNACW ++ FT DIQTRQYR EV++GS Y+T AD+WS AC+ FELATGD L
Sbjct: 484 LQVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYL 543
Query: 205 FDPHSGDNYDRDEVCVRMLL 264
F+PHSG++Y RDE + +++
Sbjct: 544 FEPHSGEDYTRDEDHIALII 563
>sp|P78362|SRPK2_HUMAN Serine/threonine-protein kinase SRPK2 OS=Homo sapiens
GN=SRPK2 PE=1 SV=3
Length = 688
Score = 111 bits (275), Expect = 9e-024
Identities = 46/73 (63%), Positives = 59/73 (80%)
Frame = +1
Query: 25 LKCKLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVL 204
++ K+ D GNACW ++ FT DIQTRQYR EV++G+ YST AD+WS AC+ FELATGD L
Sbjct: 524 IRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYL 583
Query: 205 FDPHSGDNYDRDE 243
F+PHSG++Y RDE
Sbjct: 584 FEPHSGEDYSRDE 596
>sp|O54781|SRPK2_MOUSE Serine/threonine-protein kinase SRPK2 OS=Mus musculus
GN=Srpk2 PE=1 SV=2
Length = 681
Score = 111 bits (275), Expect = 9e-024
Identities = 46/73 (63%), Positives = 59/73 (80%)
Frame = +1
Query: 25 LKCKLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVL 204
++ K+ D GNACW ++ FT DIQTRQYR EV++G+ YST AD+WS AC+ FELATGD L
Sbjct: 517 IRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYL 576
Query: 205 FDPHSGDNYDRDE 243
F+PHSG++Y RDE
Sbjct: 577 FEPHSGEDYSRDE 589
>sp|Q9UPE1|SRPK3_HUMAN Serine/threonine-protein kinase SRPK3 OS=Homo sapiens
GN=SRPK3 PE=2 SV=1
Length = 533
Score = 110 bits (274), Expect = 1e-023
Identities = 47/78 (60%), Positives = 62/78 (79%), Gaps = 1/78 (1%)
Frame = +1
Query: 13 ESAD-LKCKLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELA 189
++AD +K K+ D GNACW ++ FT DIQTRQYR EV++G++Y AD+WS AC+ FELA
Sbjct: 364 QNADKIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELA 423
Query: 190 TGDVLFDPHSGDNYDRDE 243
TGD LF+PHSG++Y RDE
Sbjct: 424 TGDYLFEPHSGEDYSRDE 441
>sp|Q9Z0G2|SRPK3_MOUSE Serine/threonine-protein kinase SRPK3 OS=Mus musculus
GN=Srpk3 PE=2 SV=1
Length = 565
Score = 110 bits (274), Expect = 1e-023
Identities = 47/78 (60%), Positives = 62/78 (79%), Gaps = 1/78 (1%)
Frame = +1
Query: 13 ESAD-LKCKLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELA 189
++AD +K K+ D GNACW ++ FT DIQTRQYR EV++G++Y AD+WS AC+ FELA
Sbjct: 396 QNADKIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELA 455
Query: 190 TGDVLFDPHSGDNYDRDE 243
TGD LF+PHSG++Y RDE
Sbjct: 456 TGDYLFEPHSGEDYSRDE 473
>sp|Q61IS6|SPK1_CAEBR Serine/threonine-protein kinase spk-1 OS=Caenorhabditis
briggsae GN=spk-1 PE=3 SV=1
Length = 771
Score = 108 bits (268), Expect = 6e-023
Identities = 46/74 (62%), Positives = 54/74 (72%)
Frame = +1
Query: 22 DLKCKLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDV 201
D+ K+ D GNACW +T DIQTRQYR EV++GS Y AD+WS AC+ FELATGD
Sbjct: 520 DIDVKIADLGNACWVNHHYTDDIQTRQYRALEVLIGSGYGPPADIWSTACMAFELATGDY 579
Query: 202 LFDPHSGDNYDRDE 243
LF+PH GDNY RDE
Sbjct: 580 LFEPHQGDNYSRDE 593
>sp|Q03563|SPK1_CAEEL Serine/threonine-protein kinase spk-1 OS=Caenorhabditis
elegans GN=spk-1 PE=1 SV=3
Length = 1003
Score = 108 bits (268), Expect = 6e-023
Identities = 46/74 (62%), Positives = 54/74 (72%)
Frame = +1
Query: 22 DLKCKLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDV 201
D+ K+ D GNACW +T DIQTRQYR EV++GS Y AD+WS AC+ FELATGD
Sbjct: 741 DIDVKIADLGNACWVNHHYTDDIQTRQYRALEVLIGSGYGPPADIWSTACMAFELATGDY 800
Query: 202 LFDPHSGDNYDRDE 243
LF+PH GDNY RDE
Sbjct: 801 LFEPHQGDNYSRDE 814
>sp|P36616|DSK1_SCHPO Protein kinase dsk1 OS=Schizosaccharomyces pombe GN=dsk1
PE=2 SV=2
Length = 544
Score = 106 bits (264), Expect = 2e-022
Identities = 44/70 (62%), Positives = 56/70 (80%)
Frame = +1
Query: 34 KLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVLFDP 213
K+ D GNACWT + FT+D+QTRQYR PEVILG ++ SAD WSFACI FEL TGD LFDP
Sbjct: 357 KIADLGNACWTRKHFTNDVQTRQYRSPEVILGCRWGASADCWSFACIIFELLTGDYLFDP 416
Query: 214 HSGDNYDRDE 243
+G++Y +++
Sbjct: 417 RNGNSYSKED 426
>sp|Q86A12|SKY1_DICDI Probable serine/threonine-protein kinase sky1
OS=Dictyostelium discoideum GN=sky1 PE=3 SV=1
Length = 656
Score = 96 bits (238), Expect = 2e-019
Identities = 41/72 (56%), Positives = 53/72 (73%)
Frame = +1
Query: 28 KCKLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVLF 207
+ +LVD GNACWT + FT DIQTRQYR PE I+ +K+ T D+WS AC+ FELATGD LF
Sbjct: 486 RAQLVDLGNACWTDKHFTDDIQTRQYRAPEAIVKAKWGTPVDIWSAACMAFELATGDHLF 545
Query: 208 DPHSGDNYDRDE 243
P SG +++ +
Sbjct: 546 KPKSGKGFEKSD 557
>sp|Q03656|SKY1_YEAST Serine/threonine-protein kinase SKY1 OS=Saccharomyces
cerevisiae GN=SKY1 PE=1 SV=1
Length = 742
Score = 91 bits (225), Expect = 6e-018
Identities = 37/73 (50%), Positives = 52/73 (71%)
Frame = +1
Query: 25 LKCKLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVL 204
++ K+ D GNACW +T+ IQTR+YR PEV+LG+ + AD+WS AC+ FEL TGD L
Sbjct: 544 IQIKIADLGNACWYDEHYTNSIQTREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFL 603
Query: 205 FDPHSGDNYDRDE 243
F+P G +Y +D+
Sbjct: 604 FEPDEGHSYTKDD 616
>sp|O43781|DYRK3_HUMAN Dual specificity tyrosine-phosphorylation-regulated
kinase 3 OS=Homo sapiens GN=DYRK3 PE=1 SV=3
Length = 588
Score = 75 bits (184), Expect = 3e-013
Identities = 38/86 (44%), Positives = 54/86 (62%), Gaps = 4/86 (4%)
Frame = +1
Query: 34 KLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVLFDP 213
K++DFG++C+ Y++ + IQ+R YR PE+ILGS+YST D+WSF CI EL TG LF
Sbjct: 352 KVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPG 411
Query: 214 HSGDNYDRDEVCVRMLLLTFMYSKLI 291
+ D++ M LL KL+
Sbjct: 412 ED----EGDQLACMMELLGMPPPKLL 433
>sp|Q4R6S5|DYRK3_MACFA Dual specificity tyrosine-phosphorylation-regulated
kinase 3 OS=Macaca fascicularis GN=DYRK3 PE=2 SV=1
Length = 568
Score = 75 bits (184), Expect = 3e-013
Identities = 38/86 (44%), Positives = 54/86 (62%), Gaps = 4/86 (4%)
Frame = +1
Query: 34 KLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVLFDP 213
K++DFG++C+ Y++ + IQ+R YR PE+ILGS+YST D+WSF CI EL TG LF
Sbjct: 332 KVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPG 391
Query: 214 HSGDNYDRDEVCVRMLLLTFMYSKLI 291
+ D++ M LL KL+
Sbjct: 392 ED----EGDQLACMMELLGMPPPKLL 413
>sp|Q5UQ24|YL205_MIMIV Putative serine/threonine-protein kinase L205
OS=Acanthamoeba polyphaga mimivirus GN=MIMI_L205 PE=3 SV=1
Length = 542
Score = 72 bits (175), Expect = 4e-012
Identities = 38/91 (41%), Positives = 55/91 (60%), Gaps = 6/91 (6%)
Frame = +1
Query: 37 LVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVLFDPH 216
L DFGN+ + ++ ++IQ R+YR PEVIL Y+ D+WS AC+ +ELATG VLFDP
Sbjct: 378 LTDFGNSYFFDKRTRNEIQDRRYRAPEVILDLNYTFCCDIWSVACVAYELATGYVLFDPF 437
Query: 217 SGDNYDRDEVCVRMLLLTFMYSKLIGFV*LS 309
+RD L F+ K++G + L+
Sbjct: 438 GEHFLNRD------LHHLFLIEKIVGEIPLA 462
>sp|P51568|AFC3_ARATH Serine/threonine-protein kinase AFC3 OS=Arabidopsis
thaliana GN=AFC3 PE=2 SV=2
Length = 400
Score = 69 bits (167), Expect = 3e-011
Identities = 37/76 (48%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Frame = +1
Query: 34 KLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVLFDP 213
KL+DFG+ R S +QTR YR PEVILG +S DLWS CI FEL TG+ LF
Sbjct: 235 KLIDFGSTVCDNRIHHSIVQTRHYRSPEVILGLGWSYQCDLWSIGCILFELCTGEALFQT 294
Query: 214 HSGDNYDRDEVCVRML 261
H DN + + R L
Sbjct: 295 H--DNLEHLAMMERAL 308
>sp|Q9V3D5|DYRK2_DROME Dual specificity tyrosine-phosphorylation-regulated
kinase 2 OS=Drosophila melanogaster GN=smi35A PE=1 SV=1
Length = 722
Score = 68 bits (164), Expect = 7e-011
Identities = 34/77 (44%), Positives = 48/77 (62%), Gaps = 3/77 (3%)
Frame = +1
Query: 34 KLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVLFDP 213
K++DFG++C+ R+ + IQ+R YR PEVILG +Y T+ D+WS CI EL TG LF
Sbjct: 341 KVIDFGSSCYVDRKIYTYIQSRFYRSPEVILGLQYGTAIDMWSLGCILAELYTGFPLF-- 398
Query: 214 HSGDNYDRDEVCVRMLL 264
G+N C+ +L
Sbjct: 399 -PGENEVEQLACIMEVL 414
>sp|Q54BC9|DYRK2_DICDI Probable serine/threonine-protein kinase dyrk2
OS=Dictyostelium discoideum GN=dyrk2 PE=3 SV=1
Length = 915
Score = 67 bits (163), Expect = 9e-011
Identities = 31/58 (53%), Positives = 40/58 (68%)
Frame = +1
Query: 34 KLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVLF 207
KL+DFG++C+ Q + IQ+R YR PEVILG+KY S D+WS CI E+ TG LF
Sbjct: 748 KLIDFGSSCFENEQIFTYIQSRFYRSPEVILGTKYDKSIDIWSLGCILVEIFTGVPLF 805
>sp|P83102|DYRK3_DROME Putative dual specificity
tyrosine-phosphorylation-regulated kinase 3 homolog OS=Drosophila
melanogaster GN=Dyrk3 PE=1 SV=3
Length = 828
Score = 66 bits (160), Expect = 2e-010
Identities = 31/73 (42%), Positives = 45/73 (61%), Gaps = 3/73 (4%)
Frame = +1
Query: 34 KLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFELATGDVLFDP 213
K++DFG++C+ ++ + IQ+R YR PEVILG KY + D+WS CI EL +G LF
Sbjct: 419 KVIDFGSSCFENQRIYTYIQSRFYRAPEVILGGKYGRAIDMWSLGCILAELLSGHALF-- 476
Query: 214 HSGDNYDRDEVCV 252
G+N C+
Sbjct: 477 -PGENESDQLACI 488
>sp|Q9NR20|DYRK4_HUMAN Dual specificity tyrosine-phosphorylation-regulated
kinase 4 OS=Homo sapiens GN=DYRK4 PE=1 SV=2
Length = 520
Score = 66 bits (160), Expect = 2e-010
Identities = 33/86 (38%), Positives = 49/86 (56%), Gaps = 3/86 (3%)
Frame = +1
Query: 7 LVESADLKCKLVDFGNACWTYRQFTSDIQTRQYRCPEVILGSKYSTSADLWSFACICFEL 186
L + K++DFG++C+ +++ + IQ+R YR PEVILG Y + D+WS CI EL
Sbjct: 238 LYQKGQASVKVIDFGSSCYEHQKVYTYIQSRFYRSPEVILGHPYDVAIDMWSLGCITAEL 297
Query: 187 ATGDVLFDPHSGDNYDRDEVCVRMLL 264
TG LF G+N C+ +L
Sbjct: 298 YTGYPLF---PGENEVEQLACIMEVL 320
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 253,397,043,485
Number of Sequences: 518415
Number of Extensions: 253397043485
Number of Successful Extensions: 1641427459
Number of sequences better than 0.0: 0
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