BLASTX 7.6.2
Query= UN78699 /QuerySize=625
(624 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54N38|UCHL5_DICDI Ubiquitin carboxyl-terminal hydrolase isoz... 158 3e-038
sp|Q9UUB6|UBLH2_SCHPO Ubiquitin carboxyl-terminal hydrolase 2 OS... 151 3e-036
sp|Q9WUP7|UCHL5_MOUSE Ubiquitin carboxyl-terminal hydrolase isoz... 140 7e-033
sp|Q9XSJ0|UCHL5_BOVIN Ubiquitin carboxyl-terminal hydrolase isoz... 139 2e-032
sp|Q9Y5K5|UCHL5_HUMAN Ubiquitin carboxyl-terminal hydrolase isoz... 139 2e-032
sp|Q06AT3|UCHL5_PIG Ubiquitin carboxyl-terminal hydrolase isozym... 139 2e-032
sp|A2VDM8|BAP1_BOVIN Ubiquitin carboxyl-terminal hydrolase BAP1 ... 127 5e-029
sp|Q09444|UBH4_CAEEL Probable ubiquitin carboxyl-terminal hydrol... 127 5e-029
sp|Q17N72|CALYP_AEDAE Ubiquitin carboxyl-terminal hydrolase caly... 118 3e-026
sp|B0W2R4|CALYP_CULQU Ubiquitin carboxyl-terminal hydrolase caly... 115 3e-025
sp|Q66JB6|BAP1_XENTR Ubiquitin carboxyl-terminal hydrolase BAP1 ... 83 1e-015
sp|Q52L14|BAP1_XENLA Ubiquitin carboxyl-terminal hydrolase BAP1 ... 82 3e-015
sp|A1L2G3|BAP1_DANRE Ubiquitin carboxyl-terminal hydrolase BAP1 ... 81 5e-015
sp|Q92560|BAP1_HUMAN Ubiquitin carboxyl-terminal hydrolase BAP1 ... 80 9e-015
sp|Q99PU7|BAP1_MOUSE Ubiquitin carboxyl-terminal hydrolase BAP1 ... 80 9e-015
sp|C4A0D9|BAP1_BRAFL Ubiquitin carboxyl-terminal hydrolase BAP1 ... 78 3e-014
sp|D3ZHS6|BAP1_RAT Ubiquitin carboxyl-terminal hydrolase BAP1 OS... 78 3e-014
sp|Q5F3N6|BAP1_CHICK Ubiquitin carboxyl-terminal hydrolase BAP1 ... 77 1e-013
>sp|Q54N38|UCHL5_DICDI Ubiquitin carboxyl-terminal hydrolase isozyme L5
OS=Dictyostelium discoideum GN=uch2 PE=3 SV=1
Length = 343
Score = 158 bits (398), Expect = 3e-038
Identities = 76/137 (55%), Positives = 99/137 (72%), Gaps = 3/137 (2%)
Frame = +3
Query: 177 WLPVESDPGVFTEIIQQMQVKGVQVEELYSLDITSLDEIRPVYGLVLLYKWRPEEKESRV 356
W +ESDPGVFTE+I ++ VK +QVEELY+LD + D ++PV GL+ L+KW EE E+R
Sbjct: 7 WCTIESDPGVFTELITKIGVKDIQVEELYTLDSSEYDRLKPVLGLIFLFKWEKEE-ENRT 65
Query: 357 VITEPNPNFFFASQIINNACATQALLSVLMNSSGIEIGSELTELKEFAKDFPPELKGLAI 536
+ N N FFA+Q+I NACATQA+LSVL+NS GIE+G EL+ K F DFPP +KG AI
Sbjct: 66 I--SDNENIFFANQVIQNACATQAILSVLLNSEGIELGEELSNFKSFVGDFPPMMKGEAI 123
Query: 537 SNNEAIRAAHNTFARPD 587
N+E I+ HN+F D
Sbjct: 124 GNSELIKETHNSFTVQD 140
>sp|Q9UUB6|UBLH2_SCHPO Ubiquitin carboxyl-terminal hydrolase 2
OS=Schizosaccharomyces pombe GN=uch2 PE=1 SV=1
Length = 300
Score = 151 bits (381), Expect = 3e-036
Identities = 74/141 (52%), Positives = 102/141 (72%), Gaps = 2/141 (1%)
Frame = +3
Query: 171 MSWLPVESDPGVFTEIIQQMQVKGVQVEELYSLDITSLDEIRPVYGLVLLYKWRPE-EKE 347
MSW +ESD GVFT++I+ + VK V+V+ELYSLD+ SL + +YG++ L+KW + +K
Sbjct: 1 MSWTTIESDAGVFTDLIENLGVKDVEVDELYSLDVDSLRQFPDIYGIIFLFKWNSKVDKP 60
Query: 348 SRVVITEPNPNFFFASQIINNACATQALLSVLMN-SSGIEIGSELTELKEFAKDFPPELK 524
+ + N FFA Q+INNACATQALLSVL+N S I++G+ L+E K+F+K PPELK
Sbjct: 61 DGTMDYDSMDNIFFAKQVINNACATQALLSVLLNHSDEIDLGTTLSEFKDFSKTLPPELK 120
Query: 525 GLAISNNEAIRAAHNTFARPD 587
G A+ N+E IR HN+FAR D
Sbjct: 121 GEALGNSEHIRCCHNSFARSD 141
>sp|Q9WUP7|UCHL5_MOUSE Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Mus
musculus GN=Uchl5 PE=2 SV=2
Length = 329
Score = 140 bits (352), Expect = 7e-033
Identities = 66/138 (47%), Positives = 100/138 (72%), Gaps = 3/138 (2%)
Frame = +3
Query: 177 WLPVESDPGVFTEIIQQMQVKGVQVEELYSLDITSLDEIRPVYGLVLLYKWRPEEKESRV 356
W +ESDPGVFTE+I+ +G QVEE++SL+ S ++++PV+GL+ L+KW+P E+ +
Sbjct: 8 WCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPESFEKLKPVHGLIFLFKWQPGEEPAGS 67
Query: 357 VITEPN-PNFFFASQIINNACATQALLSVLMNSS--GIEIGSELTELKEFAKDFPPELKG 527
V+ + FFA Q+INNACATQA++SVL+N + + +G L+E KEF++ F +KG
Sbjct: 68 VVQDSRLETIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKG 127
Query: 528 LAISNNEAIRAAHNTFAR 581
LA+SN++ IR HN+FAR
Sbjct: 128 LALSNSDVIRQVHNSFAR 145
>sp|Q9XSJ0|UCHL5_BOVIN Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Bos
taurus GN=UCHL5 PE=2 SV=1
Length = 328
Score = 139 bits (349), Expect = 2e-032
Identities = 65/138 (47%), Positives = 100/138 (72%), Gaps = 3/138 (2%)
Frame = +3
Query: 177 WLPVESDPGVFTEIIQQMQVKGVQVEELYSLDITSLDEIRPVYGLVLLYKWRPEEKESRV 356
W +ESDPGVFTE+I+ +G QVEE++SL+ + ++++PV+GL+ L+KW+P E+ +
Sbjct: 8 WCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGS 67
Query: 357 VITEPN-PNFFFASQIINNACATQALLSVLMNSS--GIEIGSELTELKEFAKDFPPELKG 527
V+ + FFA Q+INNACATQA++SVL+N + + +G L+E KEF++ F +KG
Sbjct: 68 VVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKG 127
Query: 528 LAISNNEAIRAAHNTFAR 581
LA+SN++ IR HN+FAR
Sbjct: 128 LALSNSDVIRQVHNSFAR 145
>sp|Q9Y5K5|UCHL5_HUMAN Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo
sapiens GN=UCHL5 PE=1 SV=3
Length = 329
Score = 139 bits (349), Expect = 2e-032
Identities = 65/138 (47%), Positives = 100/138 (72%), Gaps = 3/138 (2%)
Frame = +3
Query: 177 WLPVESDPGVFTEIIQQMQVKGVQVEELYSLDITSLDEIRPVYGLVLLYKWRPEEKESRV 356
W +ESDPGVFTE+I+ +G QVEE++SL+ + ++++PV+GL+ L+KW+P E+ +
Sbjct: 8 WCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGS 67
Query: 357 VITEPN-PNFFFASQIINNACATQALLSVLMNSS--GIEIGSELTELKEFAKDFPPELKG 527
V+ + FFA Q+INNACATQA++SVL+N + + +G L+E KEF++ F +KG
Sbjct: 68 VVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKG 127
Query: 528 LAISNNEAIRAAHNTFAR 581
LA+SN++ IR HN+FAR
Sbjct: 128 LALSNSDVIRQVHNSFAR 145
>sp|Q06AT3|UCHL5_PIG Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Sus
scrofa GN=UCHL5 PE=2 SV=1
Length = 329
Score = 139 bits (349), Expect = 2e-032
Identities = 65/138 (47%), Positives = 100/138 (72%), Gaps = 3/138 (2%)
Frame = +3
Query: 177 WLPVESDPGVFTEIIQQMQVKGVQVEELYSLDITSLDEIRPVYGLVLLYKWRPEEKESRV 356
W +ESDPGVFTE+I+ +G QVEE++SL+ + ++++PV+GL+ L+KW+P E+ +
Sbjct: 8 WCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGS 67
Query: 357 VITEPN-PNFFFASQIINNACATQALLSVLMNSS--GIEIGSELTELKEFAKDFPPELKG 527
V+ + FFA Q+INNACATQA++SVL+N + + +G L+E KEF++ F +KG
Sbjct: 68 VVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKG 127
Query: 528 LAISNNEAIRAAHNTFAR 581
LA+SN++ IR HN+FAR
Sbjct: 128 LALSNSDVIRQVHNSFAR 145
>sp|A2VDM8|BAP1_BOVIN Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Bos taurus
GN=BAP1 PE=2 SV=1
Length = 711
Score = 127 bits (319), Expect = 5e-029
Identities = 67/147 (45%), Positives = 89/147 (60%), Gaps = 13/147 (8%)
Frame = +3
Query: 177 WLPVESDPGVFTEIIQQMQVKGVQVEELYSLDITSLDEIRPVYGLVLLYKWRPEEKESRV 356
WL +ESDPG+FT +++ VKGVQVEE+Y L PVYG + L+KW E + R
Sbjct: 5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQG---PVYGFIFLFKWIEERRSRRK 61
Query: 357 VITEPNP----------NFFFASQIINNACATQALLSVLMNSSGIEIGSELTELKEFAKD 506
V T + N FFA Q+I N+CAT ALLSVL+N S +++G L+ +K+F K
Sbjct: 62 VSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSNVDLGPTLSRMKDFTKG 121
Query: 507 FPPELKGLAISNNEAIRAAHNTFARPD 587
F PE KG AI N + AHN+ ARP+
Sbjct: 122 FSPESKGYAIGNAPELAKAHNSHARPE 148
>sp|Q09444|UBH4_CAEEL Probable ubiquitin carboxyl-terminal hydrolase ubh-4
OS=Caenorhabditis elegans GN=ubh-4 PE=1 SV=2
Length = 321
Score = 127 bits (319), Expect = 5e-029
Identities = 67/138 (48%), Positives = 90/138 (65%), Gaps = 5/138 (3%)
Frame = +3
Query: 174 SWLPVESDPGVFTEIIQQMQVKGVQVEELYSLDITSLDEIRPVYGLVLLYKWRPEEKESR 353
SW +ESDPGVFTE+++ V G+QVEELYSLD RP YGL+ L+KWR + +
Sbjct: 6 SWCLIESDPGVFTEMLRGFGVDGLQVEELYSLD-DDKAMTRPTYGLIFLFKWR--QGDET 62
Query: 354 VVITEPNPNFFFASQIINNACATQALLSVLMN--SSGIEIGSELTELKEFAKDFPPELKG 527
I N FFA Q I NACATQAL+++LMN + +++G+ L + KEFA D P +G
Sbjct: 63 TGIPSDKQNIFFAHQTIQNACATQALINLLMNVEDTDVKLGNILNQYKEFAIDLDPNTRG 122
Query: 528 LAISNNEAIRAAHNTFAR 581
+SN+E IR HN+F+R
Sbjct: 123 HCLSNSEEIRTVHNSFSR 140
>sp|Q17N72|CALYP_AEDAE Ubiquitin carboxyl-terminal hydrolase calypso OS=Aedes
aegypti GN=calypso PE=3 SV=1
Length = 478
Score = 118 bits (295), Expect = 3e-026
Identities = 63/147 (42%), Positives = 87/147 (59%), Gaps = 12/147 (8%)
Frame = +3
Query: 177 WLPVESDPGVFTEIIQQMQVKGVQVEELYSLDITSLDEIRPVYGLVLLYKWRPEEKESRV 356
WL +ESDPG+FT +++ VKGVQVEE+Y L + PVYG + L++W E + R
Sbjct: 12 WLELESDPGLFTLLLEDFGVKGVQVEEIYDL---QKNIEGPVYGFIFLFRWIEERRARRK 68
Query: 357 VI---------TEPNPNFFFASQIINNACATQALLSVLMNSSGIEIGSELTELKEFAKDF 509
++ E N FFA Q++ N+CAT ALLSVL+N S I++G+ L+ LK K
Sbjct: 69 IVETTEIYVKDEEAVNNIFFAQQVVPNSCATHALLSVLLNCSDIDLGNTLSRLKVHTKGM 128
Query: 510 PPELKGLAISNNEAIRAAHNTFARPDS 590
PE KG AI N + AHN+ A P +
Sbjct: 129 CPENKGWAIGNTPELACAHNSHAMPQA 155
>sp|B0W2R4|CALYP_CULQU Ubiquitin carboxyl-terminal hydrolase calypso OS=Culex
quinquefasciatus GN=calypso PE=3 SV=1
Length = 470
Score = 115 bits (286), Expect = 3e-025
Identities = 61/148 (41%), Positives = 87/148 (58%), Gaps = 13/148 (8%)
Frame = +3
Query: 177 WLPVESDPGVFTEIIQQMQVKGVQVEELYSLDITSLDEIRPVYGLVLLYKWRPEEKESRV 356
WL +ESDPG+FT +++ VKGVQVEE+Y L T PV+G + L++W E + R
Sbjct: 12 WLELESDPGLFTLLLEDFGVKGVQVEEIYDLQKTIEG---PVFGFIFLFRWIEERRARRK 68
Query: 357 VI----------TEPNPNFFFASQIINNACATQALLSVLMNSSGIEIGSELTELKEFAKD 506
++ E + FFA Q++ N+CAT ALLSVL+N S I++G+ L+ LK K
Sbjct: 69 IVETTTEMYVKDEEAVNSIFFAHQVVPNSCATHALLSVLLNCSDIDLGTTLSRLKVHTKG 128
Query: 507 FPPELKGLAISNNEAIRAAHNTFARPDS 590
P+ KG AI N + AHN+ A P +
Sbjct: 129 MCPDNKGWAIGNTPELACAHNSHAMPQA 156
>sp|Q66JB6|BAP1_XENTR Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Xenopus
tropicalis GN=bap1 PE=2 SV=1
Length = 685
Score = 83 bits (204), Expect = 1e-015
Identities = 41/81 (50%), Positives = 54/81 (66%)
Frame = +3
Query: 345 ESRVVITEPNPNFFFASQIINNACATQALLSVLMNSSGIEIGSELTELKEFAKDFPPELK 524
++ V+ E N FFA Q+I N+CAT ALLSVL+N SG+ +G L+ +KEF K F PE K
Sbjct: 68 DTSVMEDEVVNNMFFAHQLIPNSCATHALLSVLLNCSGVHLGPTLSRIKEFTKGFSPESK 127
Query: 525 GLAISNNEAIRAAHNTFARPD 587
G AI N + AHN+ ARP+
Sbjct: 128 GYAIGNAPELAKAHNSHARPE 148
>sp|Q52L14|BAP1_XENLA Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Xenopus
laevis GN=bap1 PE=2 SV=1
Length = 618
Score = 82 bits (200), Expect = 3e-015
Identities = 40/81 (49%), Positives = 53/81 (65%)
Frame = +3
Query: 345 ESRVVITEPNPNFFFASQIINNACATQALLSVLMNSSGIEIGSELTELKEFAKDFPPELK 524
++ V+ E N FFA Q+I N+CAT ALLSVL+N G+ +G L+ +KEF K F PE K
Sbjct: 68 DTSVMEDEVVNNMFFAHQLIPNSCATHALLSVLLNCGGVHLGPTLSRIKEFTKGFSPESK 127
Query: 525 GLAISNNEAIRAAHNTFARPD 587
G AI N + AHN+ ARP+
Sbjct: 128 GYAIGNAPELAKAHNSHARPE 148
>sp|A1L2G3|BAP1_DANRE Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Danio rerio
GN=bap1 PE=2 SV=2
Length = 755
Score = 81 bits (198), Expect = 5e-015
Identities = 40/81 (49%), Positives = 54/81 (66%)
Frame = +3
Query: 345 ESRVVITEPNPNFFFASQIINNACATQALLSVLMNSSGIEIGSELTELKEFAKDFPPELK 524
E+ V+ + + FFA Q+I N+CAT ALLSVL+N SG+E+G L+ +K F K F PE K
Sbjct: 68 ETSVIDDDIVNDMFFAHQLIPNSCATHALLSVLLNCSGVELGMTLSRMKAFTKGFNPESK 127
Query: 525 GLAISNNEAIRAAHNTFARPD 587
G AI N + AHN+ ARP+
Sbjct: 128 GYAIGNAPELAKAHNSHARPE 148
>sp|Q92560|BAP1_HUMAN Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Homo sapiens
GN=BAP1 PE=1 SV=2
Length = 729
Score = 80 bits (196), Expect = 9e-015
Identities = 37/70 (52%), Positives = 49/70 (70%)
Frame = +3
Query: 378 NFFFASQIINNACATQALLSVLMNSSGIEIGSELTELKEFAKDFPPELKGLAISNNEAIR 557
N FFA Q+I N+CAT ALLSVL+N S +++G L+ +K+F K F PE KG AI N +
Sbjct: 79 NMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELA 138
Query: 558 AAHNTFARPD 587
AHN+ ARP+
Sbjct: 139 KAHNSHARPE 148
>sp|Q99PU7|BAP1_MOUSE Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Mus musculus
GN=Bap1 PE=1 SV=1
Length = 728
Score = 80 bits (196), Expect = 9e-015
Identities = 37/70 (52%), Positives = 49/70 (70%)
Frame = +3
Query: 378 NFFFASQIINNACATQALLSVLMNSSGIEIGSELTELKEFAKDFPPELKGLAISNNEAIR 557
N FFA Q+I N+CAT ALLSVL+N S +++G L+ +K+F K F PE KG AI N +
Sbjct: 79 NMFFAHQLIPNSCATHALLSVLLNCSNVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELA 138
Query: 558 AAHNTFARPD 587
AHN+ ARP+
Sbjct: 139 KAHNSHARPE 148
>sp|C4A0D9|BAP1_BRAFL Ubiquitin carboxyl-terminal hydrolase BAP1
OS=Branchiostoma floridae GN=BAP1 PE=3 SV=1
Length = 694
Score = 78 bits (191), Expect = 3e-014
Identities = 43/85 (50%), Positives = 53/85 (62%)
Frame = +3
Query: 333 PEEKESRVVITEPNPNFFFASQIINNACATQALLSVLMNSSGIEIGSELTELKEFAKDFP 512
P +ES VV + + FFA Q+I N+CAT ALLSVL+N I +GS LT LK F +
Sbjct: 64 PSMEESFVVDEDIVNDMFFAQQLIPNSCATHALLSVLLNCPQISLGSTLTRLKYFTRGMG 123
Query: 513 PELKGLAISNNEAIRAAHNTFARPD 587
PE KG AI N I AHN+ ARP+
Sbjct: 124 PESKGWAIGNVPEIARAHNSHARPE 148
>sp|D3ZHS6|BAP1_RAT Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Rattus
norvegicus GN=Bap1 PE=3 SV=2
Length = 727
Score = 78 bits (191), Expect = 3e-014
Identities = 36/70 (51%), Positives = 49/70 (70%)
Frame = +3
Query: 378 NFFFASQIINNACATQALLSVLMNSSGIEIGSELTELKEFAKDFPPELKGLAISNNEAIR 557
+ FFA Q+I N+CAT ALLSVL+N S +++G L+ +K+F K F PE KG AI N +
Sbjct: 79 SMFFAHQLIPNSCATHALLSVLLNCSNVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELA 138
Query: 558 AAHNTFARPD 587
AHN+ ARP+
Sbjct: 139 KAHNSHARPE 148
>sp|Q5F3N6|BAP1_CHICK Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Gallus
gallus GN=BAP1 PE=2 SV=1
Length = 700
Score = 77 bits (187), Expect = 1e-013
Identities = 37/81 (45%), Positives = 53/81 (65%)
Frame = +3
Query: 345 ESRVVITEPNPNFFFASQIINNACATQALLSVLMNSSGIEIGSELTELKEFAKDFPPELK 524
E+ V+ + N FFA Q+I N+CAT ALLSVL+N + +++G L+ +K+F K F PE K
Sbjct: 68 ETSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCNNVDLGPTLSRMKDFTKGFSPESK 127
Query: 525 GLAISNNEAIRAAHNTFARPD 587
G AI N + A N+ ARP+
Sbjct: 128 GYAIGNAPELAKARNSHARPE 148
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 253,397,043,485
Number of Sequences: 518415
Number of Extensions: 253397043485
Number of Successful Extensions: 1641427459
Number of sequences better than 0.0: 0
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