BLASTX 7.6.2
Query= UN78729 /QuerySize=601
(600 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q3ZBV1|IST1_BOVIN IST1 homolog OS=Bos taurus GN=IST1 PE=2 SV=1 97 9e-020
sp|P53990|IST1_HUMAN IST1 homolog OS=Homo sapiens GN=KIAA0174 PE... 97 9e-020
sp|Q9CX00|IST1_MOUSE IST1 homolog OS=Mus musculus GN=Ist1 PE=2 SV=1 97 9e-020
sp|Q568Z6|IST1_RAT IST1 homolog OS=Rattus norvegicus GN=Ist1 PE=... 97 9e-020
sp|Q5R6G8|IST1_PONAB IST1 homolog OS=Pongo abelii GN=IST1 PE=2 SV=1 94 6e-019
sp|Q54I39|IST1L_DICDI IST1-like protein OS=Dictyostelium discoid... 87 7e-017
sp|P53843|IST1_YEAST Vacuolar protein sorting-associated protein... 53 1e-006
>sp|Q3ZBV1|IST1_BOVIN IST1 homolog OS=Bos taurus GN=IST1 PE=2 SV=1
Length = 364
Score = 97 bits (239), Expect = 9e-020
Identities = 53/121 (43%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 182 KTSLNFAIARMKLLQNKRDMHLKHMKKEIAQFLQAGQEPIARIRVEHVIREMNLWAAYEI 361
+ +L I R+KLL+ K+ + +KEIA +L AG++ ARIRVEH+IRE L A EI
Sbjct: 12 RVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEI 71
Query: 362 LELFCEFVLARVPILESQKECPRELREAIASIIFAAPRC-SEVPDLLQLKNLFGTKYGKE 538
LEL+C+ +LAR +++S KE L E+++++I+AAPR SEV +L + + KY KE
Sbjct: 72 LELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKE 131
Query: 539 F 541
+
Sbjct: 132 Y 132
>sp|P53990|IST1_HUMAN IST1 homolog OS=Homo sapiens GN=KIAA0174 PE=1 SV=1
Length = 364
Score = 97 bits (239), Expect = 9e-020
Identities = 53/121 (43%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 182 KTSLNFAIARMKLLQNKRDMHLKHMKKEIAQFLQAGQEPIARIRVEHVIREMNLWAAYEI 361
+ +L I R+KLL+ K+ + +KEIA +L AG++ ARIRVEH+IRE L A EI
Sbjct: 12 RVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEI 71
Query: 362 LELFCEFVLARVPILESQKECPRELREAIASIIFAAPRC-SEVPDLLQLKNLFGTKYGKE 538
LEL+C+ +LAR +++S KE L E+++++I+AAPR SEV +L + + KY KE
Sbjct: 72 LELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKE 131
Query: 539 F 541
+
Sbjct: 132 Y 132
>sp|Q9CX00|IST1_MOUSE IST1 homolog OS=Mus musculus GN=Ist1 PE=2 SV=1
Length = 362
Score = 97 bits (239), Expect = 9e-020
Identities = 53/121 (43%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 182 KTSLNFAIARMKLLQNKRDMHLKHMKKEIAQFLQAGQEPIARIRVEHVIREMNLWAAYEI 361
+ +L I R+KLL+ K+ + +KEIA +L AG++ ARIRVEH+IRE L A EI
Sbjct: 12 RVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEI 71
Query: 362 LELFCEFVLARVPILESQKECPRELREAIASIIFAAPRC-SEVPDLLQLKNLFGTKYGKE 538
LEL+C+ +LAR +++S KE L E+++++I+AAPR SEV +L + + KY KE
Sbjct: 72 LELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKE 131
Query: 539 F 541
+
Sbjct: 132 Y 132
>sp|Q568Z6|IST1_RAT IST1 homolog OS=Rattus norvegicus GN=Ist1 PE=2 SV=1
Length = 366
Score = 97 bits (239), Expect = 9e-020
Identities = 53/121 (43%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 182 KTSLNFAIARMKLLQNKRDMHLKHMKKEIAQFLQAGQEPIARIRVEHVIREMNLWAAYEI 361
+ +L I R+KLL+ K+ + +KEIA +L AG++ ARIRVEH+IRE L A EI
Sbjct: 12 RVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEI 71
Query: 362 LELFCEFVLARVPILESQKECPRELREAIASIIFAAPRC-SEVPDLLQLKNLFGTKYGKE 538
LEL+C+ +LAR +++S KE L E+++++I+AAPR SEV +L + + KY KE
Sbjct: 72 LELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKE 131
Query: 539 F 541
+
Sbjct: 132 Y 132
>sp|Q5R6G8|IST1_PONAB IST1 homolog OS=Pongo abelii GN=IST1 PE=2 SV=1
Length = 364
Score = 94 bits (232), Expect = 6e-019
Identities = 52/121 (42%), Positives = 79/121 (65%), Gaps = 1/121 (0%)
Frame = +2
Query: 182 KTSLNFAIARMKLLQNKRDMHLKHMKKEIAQFLQAGQEPIARIRVEHVIREMNLWAAYEI 361
+ +L I R+KLL+ K+ + +KEIA +L AG++ ARIRVEH+IRE L A EI
Sbjct: 12 RVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEI 71
Query: 362 LELFCEFVLARVPILESQKECPRELREAIASIIFAAPRC-SEVPDLLQLKNLFGTKYGKE 538
LEL+C+ +LAR +++S KE L E+++++I+AAPR SEV +L + + KY K
Sbjct: 72 LELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKG 131
Query: 539 F 541
+
Sbjct: 132 Y 132
>sp|Q54I39|IST1L_DICDI IST1-like protein OS=Dictyostelium discoideum
GN=DDB_G0289029 PE=3 SV=1
Length = 369
Score = 87 bits (214), Expect = 7e-017
Identities = 41/118 (34%), Positives = 78/118 (66%), Gaps = 1/118 (0%)
Frame = +2
Query: 182 KTSLNFAIARMKLLQNKRDMHLKHMKKEIAQFLQAGQEPIARIRVEHVIREMNLWAAYEI 361
K L A++R+++L+NK+ ++ K+ +A+ L+ E ARIRVE +IR+ L ++I
Sbjct: 14 KVQLKLAVSRIQILKNKKANIVRDEKRNVAELLRKKNEESARIRVETIIRDEYLIECFQI 73
Query: 362 LELFCEFVLARVPILESQKECPRELREAIASIIFAAPRCSEVPDLLQLKNLFGTKYGK 535
+E+ CE + AR+ ++ + E P E++E+I ++++++ R ++P+L Q+KN KYGK
Sbjct: 74 IEVLCELLHARINLINATTEMPLEMKESIFTLVYSSQRI-QIPELEQIKNQLKAKYGK 130
>sp|P53843|IST1_YEAST Vacuolar protein sorting-associated protein IST1
OS=Saccharomyces cerevisiae GN=IST1 PE=1 SV=1
Length = 298
Score = 53 bits (126), Expect = 1e-006
Identities = 29/80 (36%), Positives = 44/80 (55%)
Frame = +2
Query: 167 YVIGSKTSLNFAIARMKLLQNKRDMHLKHMKKEIAQFLQAGQEPIARIRVEHVIREMNLW 346
+ I KT L I R++ Q K+ K ++++AQ L +E A RVE +I +
Sbjct: 8 FTIKLKTCLKMCIQRLRYAQEKQQAIAKQSRRQVAQLLLTNKEQKAHYRVETLIHDDIHI 67
Query: 347 AAYEILELFCEFVLARVPIL 406
EILEL+CE +LARV ++
Sbjct: 68 ELLEILELYCELLLARVQVI 87
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 253,397,043,485
Number of Sequences: 518415
Number of Extensions: 253397043485
Number of Successful Extensions: 1641427459
Number of sequences better than 0.0: 0
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