BLASTX 7.6.2
Query= UN81553 /QuerySize=535
(534 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54Z26|GLYC1_DICDI Serine hydroxymethyltransferase 1 OS=Dicty... 89 1e-017
sp|Q54EW1|GLYC2_DICDI Serine hydroxymethyltransferase 2 OS=Dicty... 89 2e-017
sp|P50432|GLYC_CAEEL Serine hydroxymethyltransferase OS=Caenorha... 84 5e-016
sp|Q60V73|GLYC_CAEBR Serine hydroxymethyltransferase OS=Caenorha... 79 1e-014
sp|Q9SZJ5|GLYM_ARATH Serine hydroxymethyltransferase, mitochondr... 72 2e-012
sp|Q5RFK5|GLYC_PONAB Serine hydroxymethyltransferase, cytosolic ... 72 2e-012
sp|P50433|GLYM_SOLTU Serine hydroxymethyltransferase, mitochondr... 71 3e-012
sp|P34896|GLYC_HUMAN Serine hydroxymethyltransferase, cytosolic ... 71 4e-012
sp|Q5E9P9|GLYC_BOVIN Serine hydroxymethyltransferase, cytosolic ... 70 9e-012
sp|P07511|GLYC_RABIT Serine hydroxymethyltransferase, cytosolic ... 70 9e-012
sp|Q6FQ44|GLYM_CANGA Serine hydroxymethyltransferase, mitochondr... 69 2e-011
sp|P50431|GLYC_MOUSE Serine hydroxymethyltransferase, cytosolic ... 69 2e-011
sp|P35623|GLYC_SHEEP Serine hydroxymethyltransferase, cytosolic ... 69 2e-011
sp|P34899|GLYM_PEA Serine hydroxymethyltransferase, mitochondria... 68 3e-011
sp|P34898|GLYC_NEUCR Serine hydroxymethyltransferase, cytosolic ... 66 1e-010
sp|P49357|GLYM_FLAPR Serine hydroxymethyltransferase 1, mitochon... 66 1e-010
sp|P49358|GLYN_FLAPR Serine hydroxymethyltransferase 2, mitochon... 65 3e-010
sp|Q75BQ6|GLYC_ASHGO Serine hydroxymethyltransferase, cytosolic ... 64 4e-010
sp|P37291|GLYC_YEAST Serine hydroxymethyltransferase, cytosolic ... 61 3e-009
sp|O13425|GLYM_CANAL Serine hydroxymethyltransferase, mitochondr... 60 7e-009
>sp|Q54Z26|GLYC1_DICDI Serine hydroxymethyltransferase 1 OS=Dictyostelium
discoideum GN=shmt1 PE=1 SV=1
Length = 457
Score = 89 bits (219), Expect = 1e-017
Identities = 42/96 (43%), Positives = 64/96 (66%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
++ +IT+NK A+ GD ISPGG+RIG+ A+T+RG E+DFE IADFL + I+ +Q
Sbjct: 360 DIANITVNKNAVHGDTNAISPGGIRIGSSALTSRGLKEADFEKIADFLDRIVSISLEIQG 419
Query: 189 EHGKSHKEFVKSLCSNKDICDLRNRVEAFALQYEMP 296
GK +FV + +K++ DLR VE F+ ++ +P
Sbjct: 420 RVGKKLVDFVVEINKSKELLDLRKEVEEFSSKFTLP 455
>sp|Q54EW1|GLYC2_DICDI Serine hydroxymethyltransferase 2 OS=Dictyostelium
discoideum GN=shmt2 PE=3 SV=1
Length = 481
Score = 89 bits (218), Expect = 2e-017
Identities = 38/93 (40%), Positives = 62/93 (66%)
Frame = +3
Query: 18 HITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQREHG 197
HIT+NK A++GD I+PGGVR+G PA+T+RG E DF + DFL + +I+ +Q + G
Sbjct: 386 HITVNKNAVYGDTNAIAPGGVRLGAPALTSRGLKEQDFVKVVDFLDRVVKISLDIQSKVG 445
Query: 198 KSHKEFVKSLCSNKDICDLRNRVEAFALQYEMP 296
K +F +++ N+D+ +R V+ F+ ++ MP
Sbjct: 446 KKMPDFQRAIADNQDLKQIRQEVKEFSTKFGMP 478
>sp|P50432|GLYC_CAEEL Serine hydroxymethyltransferase OS=Caenorhabditis elegans
GN=mel-32 PE=1 SV=2
Length = 507
Score = 84 bits (206), Expect = 5e-016
Identities = 41/100 (41%), Positives = 59/100 (59%), Gaps = 4/100 (4%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
++ HI NK GD + PGG+R+GTPA+T+RG E DFE + DF+ + QI
Sbjct: 403 DLAHIACNKNTCPGDVSALRPGGIRLGTPALTSRGFQEQDFEKVGDFIHEGVQIAKKYNA 462
Query: 189 EHGKSHKEFVKSLCSN----KDICDLRNRVEAFALQYEMP 296
E GK+ K+F +N KD+ DL RVE F+ ++E+P
Sbjct: 463 EAGKTLKDFKSFTETNEPFKKDVADLAKRVEEFSTKFEIP 502
>sp|Q60V73|GLYC_CAEBR Serine hydroxymethyltransferase OS=Caenorhabditis briggsae
GN=mel-32 PE=3 SV=3
Length = 511
Score = 79 bits (194), Expect = 1e-014
Identities = 38/100 (38%), Positives = 59/100 (59%), Gaps = 4/100 (4%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
++ HI NK GD + PGG+R+GTPA+T+RG E DFE + DF+ + QI
Sbjct: 407 DLAHIACNKNTCPGDVSALRPGGIRLGTPALTSRGFKEQDFEKVGDFIHEGVQIAKKYNA 466
Query: 189 EHGKSHKEFVKSLCSN----KDICDLRNRVEAFALQYEMP 296
E GK+ K+F +N +++ +L RVE F+ ++E+P
Sbjct: 467 EAGKTLKDFKAFTATNEQFKQEVAELAKRVEEFSGKFEIP 506
>sp|Q9SZJ5|GLYM_ARATH Serine hydroxymethyltransferase, mitochondrial
OS=Arabidopsis thaliana GN=SHM1 PE=1 SV=1
Length = 517
Score = 72 bits (175), Expect = 2e-012
Identities = 39/98 (39%), Positives = 58/98 (59%), Gaps = 5/98 (5%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E HI NK + GD + PGG+R+GTPA+T+RG +E DF +A++ KA I ++
Sbjct: 406 EAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKS 465
Query: 189 E-HGKSHKEFVKSLCSN----KDICDLRNRVEAFALQY 287
E G K+FV ++ S+ +I LR+ VE FA Q+
Sbjct: 466 EAQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 503
>sp|Q5RFK5|GLYC_PONAB Serine hydroxymethyltransferase, cytosolic OS=Pongo abelii
GN=SHMT1 PE=2 SV=1
Length = 483
Score = 72 bits (174), Expect = 2e-012
Identities = 37/101 (36%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E C I NK GD + P G+R+GTPA+T+RG +E DF+ +A F+ + ++T +Q
Sbjct: 378 EACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQS 437
Query: 189 EHG--KSHKEFVKSLCSNK---DICDLRNRVEAFALQYEMP 296
+ G + KEF + L +K + LR +VE+FA + +P
Sbjct: 438 DTGVRATLKEFKERLAGDKYQGAVQALREKVESFASLFPLP 478
>sp|P50433|GLYM_SOLTU Serine hydroxymethyltransferase, mitochondrial OS=Solanum
tuberosum PE=2 SV=1
Length = 518
Score = 71 bits (173), Expect = 3e-012
Identities = 40/98 (40%), Positives = 58/98 (59%), Gaps = 5/98 (5%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E HI NK + GD + PGG+R+GTPA+T+RG +E DF +ADF A +I ++
Sbjct: 407 EAVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFLEEDFVKVADFFDAAVKIAVKVKA 466
Query: 189 E-HGKSHKEFVKSLCSN----KDICDLRNRVEAFALQY 287
E G K+FV +L S+ +I LR+ VE +A Q+
Sbjct: 467 ETQGTKLKDFVATLESSAPIKSEIAKLRHDVEEYAKQF 504
>sp|P34896|GLYC_HUMAN Serine hydroxymethyltransferase, cytosolic OS=Homo sapiens
GN=SHMT1 PE=1 SV=1
Length = 483
Score = 71 bits (172), Expect = 4e-012
Identities = 37/101 (36%), Positives = 58/101 (57%), Gaps = 5/101 (4%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E C I NK GD + P G+R+GTPA+T+RG +E DF+ +A F+ + ++T +Q
Sbjct: 378 EACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQS 437
Query: 189 EHG--KSHKEFVKSLCSNK---DICDLRNRVEAFALQYEMP 296
+ G + KEF + L +K + LR VE+FA + +P
Sbjct: 438 DTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLP 478
>sp|Q5E9P9|GLYC_BOVIN Serine hydroxymethyltransferase, cytosolic OS=Bos taurus
GN=SHMT1 PE=2 SV=3
Length = 484
Score = 70 bits (169), Expect = 9e-012
Identities = 36/102 (35%), Positives = 58/102 (56%), Gaps = 6/102 (5%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E C I NK GD + P G+R+GTPA+T+RG +E DF+ +A F+ + ++T +Q
Sbjct: 378 EACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQIQD 437
Query: 189 EHG--KSHKEFVKSLCS----NKDICDLRNRVEAFALQYEMP 296
G + KEF++ L ++ + LR VE+FA + +P
Sbjct: 438 AVGVKATLKEFMEKLAGAEEHHRAVAALRAEVESFATLFPLP 479
>sp|P07511|GLYC_RABIT Serine hydroxymethyltransferase, cytosolic OS=Oryctolagus
cuniculus GN=SHMT1 PE=1 SV=2
Length = 484
Score = 70 bits (169), Expect = 9e-012
Identities = 36/102 (35%), Positives = 58/102 (56%), Gaps = 6/102 (5%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E C I NK GD + P G+R+GTPA+T+RG +E DF+ +A F+ + ++T +Q
Sbjct: 378 EACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTVQIQD 437
Query: 189 EHG--KSHKEFVKSLCSN----KDICDLRNRVEAFALQYEMP 296
+ G + KEF + L + + + LR VE+FA + +P
Sbjct: 438 DTGPRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLP 479
>sp|Q6FQ44|GLYM_CANGA Serine hydroxymethyltransferase, mitochondrial OS=Candida
glabrata GN=SHM1 PE=3 SV=1
Length = 485
Score = 69 bits (167), Expect = 2e-011
Identities = 34/90 (37%), Positives = 51/90 (56%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E +I NK I GD + P G+R+GTPAMTTRG E DF+ +A+++ A +++ AL+
Sbjct: 380 EKINIAANKNTIPGDKSALFPSGLRVGTPAMTTRGFQEQDFKKVAEYIDNAVKLSIALKS 439
Query: 189 EHGKSHKEFVKSLCSNKDICDLRNRVEAFA 278
+ K+ L S K +CD V+ A
Sbjct: 440 QESADAKDVRSKLNSFKQLCDQSEPVQKLA 469
>sp|P50431|GLYC_MOUSE Serine hydroxymethyltransferase, cytosolic OS=Mus musculus
GN=Shmt1 PE=1 SV=2
Length = 478
Score = 69 bits (166), Expect = 2e-011
Identities = 36/102 (35%), Positives = 55/102 (53%), Gaps = 6/102 (5%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E C I NK GD + P G+R+GTPA+T+RG +E DF+ +A F+ + ++T +Q
Sbjct: 372 EACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQIQS 431
Query: 189 EHG--KSHKEFVKSLCSNKDI----CDLRNRVEAFALQYEMP 296
+ KEF + L ++ I LR VE FA + +P
Sbjct: 432 HMATKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLP 473
>sp|P35623|GLYC_SHEEP Serine hydroxymethyltransferase, cytosolic OS=Ovis aries
GN=SHMT1 PE=1 SV=3
Length = 484
Score = 69 bits (166), Expect = 2e-011
Identities = 36/102 (35%), Positives = 57/102 (55%), Gaps = 6/102 (5%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E C I NK GD + P G+R+GTPA+T+RG +E DF +A F+ + ++T +Q
Sbjct: 378 EACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFRKVAHFIHRGIELTLQIQD 437
Query: 189 EHG--KSHKEFVKSLCSNKD----ICDLRNRVEAFALQYEMP 296
G + KEF++ L ++ + LR VE+FA + +P
Sbjct: 438 AVGVKATLKEFMEKLAGAEEHQRAVTALRAEVESFATLFPLP 479
>sp|P34899|GLYM_PEA Serine hydroxymethyltransferase, mitochondrial OS=Pisum
sativum PE=1 SV=1
Length = 518
Score = 68 bits (165), Expect = 3e-011
Identities = 36/98 (36%), Positives = 59/98 (60%), Gaps = 5/98 (5%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E+ HI NK + GD + PGG+R+GTPA+T+RG +E DF +A++ A + ++
Sbjct: 407 ELVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDAAVSLALKVKA 466
Query: 189 E-HGKSHKEFVKSLCSN----KDICDLRNRVEAFALQY 287
E G K+FV++L ++ +I L++ VE FA Q+
Sbjct: 467 ESKGTKLKDFVEALQTSSYVQSEISKLKHDVEEFAKQF 504
>sp|P34898|GLYC_NEUCR Serine hydroxymethyltransferase, cytosolic OS=Neurospora
crassa GN=for PE=3 SV=2
Length = 480
Score = 66 bits (160), Expect = 1e-010
Identities = 35/101 (34%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E +IT NK A+ GD ++PGG+RIGTPAMT+RG E+DFE +A F+ +A ++ +Q
Sbjct: 370 EQINITCNKNAVPGDKSALTPGGLRIGTPAMTSRGFGEADFEKVAVFVDEAVKLCKEIQA 429
Query: 189 ---EHGKSHKEFVKSLCSN--KDICDLRNRVEAFALQYEMP 296
+ K+F + ++ I +L+ + A++ + +P
Sbjct: 430 SLPKEANKQKDFKAKIATSDIPRINELKQEIAAWSNTFPLP 470
>sp|P49357|GLYM_FLAPR Serine hydroxymethyltransferase 1, mitochondrial
OS=Flaveria pringlei PE=2 SV=1
Length = 517
Score = 66 bits (160), Expect = 1e-010
Identities = 37/97 (38%), Positives = 57/97 (58%), Gaps = 4/97 (4%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E HI NK + GD + PGG+R+GTPA+T+RG +E DF +A F A ++ ++
Sbjct: 407 EAVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYFFDLAVKLAVKIKG 466
Query: 189 E-HGKSHKEFVKSLCSN---KDICDLRNRVEAFALQY 287
E G K+FV ++ S+ +I LR+ VE +A Q+
Sbjct: 467 EAKGTKLKDFVTAMESSAIQSEISKLRHDVEEYAKQF 503
>sp|P49358|GLYN_FLAPR Serine hydroxymethyltransferase 2, mitochondrial
OS=Flaveria pringlei PE=2 SV=1
Length = 517
Score = 65 bits (156), Expect = 3e-010
Identities = 36/97 (37%), Positives = 56/97 (57%), Gaps = 4/97 (4%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E HI NK + GD + PGG+R+GTPA+T+RG +E DF +A A ++ ++
Sbjct: 407 EAVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYLFDLAVKLAVKIKG 466
Query: 189 E-HGKSHKEFVKSLCSN---KDICDLRNRVEAFALQY 287
E G K+FV ++ S+ +I LR+ VE +A Q+
Sbjct: 467 EAQGTKLKDFVAAMQSSAFQSEISKLRHDVEEYAKQF 503
>sp|Q75BQ6|GLYC_ASHGO Serine hydroxymethyltransferase, cytosolic OS=Ashbya
gossypii GN=SHM2 PE=3 SV=1
Length = 469
Score = 64 bits (155), Expect = 4e-010
Identities = 37/100 (37%), Positives = 54/100 (54%), Gaps = 4/100 (4%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E +I LNK +I GD + PGGVRIG PAMTTRG E DF I ++ +A +I ++Q+
Sbjct: 369 EKINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFARIVGYINRAVEIARSIQQ 428
Query: 189 EHGKSH---KEFVKSLCSNKD-ICDLRNRVEAFALQYEMP 296
K K+F + D I L + ++ +Y +P
Sbjct: 429 SLPKEANRLKDFKAKVEGGTDEIAQLAQEIYSWTEEYPLP 468
>sp|P37291|GLYC_YEAST Serine hydroxymethyltransferase, cytosolic
OS=Saccharomyces cerevisiae GN=SHM2 PE=1 SV=2
Length = 469
Score = 61 bits (147), Expect = 3e-009
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQR 188
E +I LNK +I GD + PGGVRIG PAMTTRG E DF I ++ KA + +Q+
Sbjct: 369 EKINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFHRIVQYINKAVEFAQQVQQ 428
Query: 189 EHGKSH---KEFVKSLCSNKDI 245
K K+F + D+
Sbjct: 429 SLPKDACRLKDFKAKVDEGSDV 450
>sp|O13425|GLYM_CANAL Serine hydroxymethyltransferase, mitochondrial OS=Candida
albicans GN=SHM1 PE=3 SV=1
Length = 493
Score = 60 bits (144), Expect = 7e-009
Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +3
Query: 9 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETIADFLMKAAQITSALQ- 185
E +I NK + GD + P G+R+GTPAMTTRG +F+ +A+F+ +A I L+
Sbjct: 390 ERANIAANKNTVPGDVSALFPSGLRVGTPAMTTRGFGPEEFDKVAEFIDQAVNIAIELKA 449
Query: 186 REHGKSHKEFV---KSLCSNKD-ICDLRNRVEAFALQYEMP 296
+E GK KE + K L D + L V ++ +Y +P
Sbjct: 450 QEQGKVPKELLASFKKLADESDKVKQLDKEVVSWVSKYPVP 490
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 259,818,014,972
Number of Sequences: 518415
Number of Extensions: 259818014972
Number of Successful Extensions: 1673700095
Number of sequences better than 0.0: 0
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