BLASTX 7.6.2
Query= UN82609 /QuerySize=808
(807 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q15329|E2F5_HUMAN Transcription factor E2F5 OS=Homo sapiens G... 110 1e-023
sp|O00716|E2F3_HUMAN Transcription factor E2F3 OS=Homo sapiens G... 109 3e-023
sp|O35261|E2F3_MOUSE Transcription factor E2F3 OS=Mus musculus G... 109 3e-023
sp|Q61502|E2F5_MOUSE Transcription factor E2F5 OS=Mus musculus G... 107 1e-022
sp|Q16254|E2F4_HUMAN Transcription factor E2F4 OS=Homo sapiens G... 102 3e-021
sp|Q8R0K9|E2F4_MOUSE Transcription factor E2F4 OS=Mus musculus G... 102 3e-021
sp|Q62814|E2F5_RAT Transcription factor E2F5 (Fragment) OS=Rattu... 102 5e-021
sp|Q14209|E2F2_HUMAN Transcription factor E2F2 OS=Homo sapiens G... 99 3e-020
sp|P56931|E2F2_MOUSE Transcription factor E2F2 OS=Mus musculus G... 99 3e-020
sp|Q27368|E2F_DROME Transcription factor E2f OS=Drosophila melan... 91 8e-018
sp|Q90977|E2F1_CHICK Transcription factor E2F1 OS=Gallus gallus ... 90 1e-017
sp|Q01094|E2F1_HUMAN Transcription factor E2F1 OS=Homo sapiens G... 89 2e-017
sp|Q61501|E2F1_MOUSE Transcription factor E2F1 OS=Mus musculus G... 89 2e-017
sp|Q08DY6|E2F6_BOVIN Transcription factor E2F6 OS=Bos taurus GN=... 88 5e-017
sp|O75461|E2F6_HUMAN Transcription factor E2F6 OS=Homo sapiens G... 88 5e-017
sp|O54917|E2F6_MOUSE Transcription factor E2F6 OS=Mus musculus G... 87 2e-016
sp|O09139|E2F1_RAT Transcription factor E2F1 (Fragment) OS=Rattu... 56 3e-007
sp|A0AVK6|E2F8_HUMAN Transcription factor E2F8 OS=Homo sapiens G... 55 5e-007
sp|Q58FA4|E2F8_MOUSE Transcription factor E2F8 OS=Mus musculus G... 53 2e-006
>sp|Q15329|E2F5_HUMAN Transcription factor E2F5 OS=Homo sapiens GN=E2F5 PE=1
SV=1
Length = 346
Score = 110 bits (274), Expect = 1e-023
Identities = 67/134 (50%), Positives = 85/134 (63%), Gaps = 5/134 (3%)
Frame = +2
Query: 419 AKGGRVNTKSKAKGNQSVPQTPISNAIVGSPPTL---TPSGSCRYDSSLGLLTKKFVNLI 589
A G+ + +G + PQ P + A PP GS R++ SLGLLT KFV+L+
Sbjct: 7 ASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTTKFVSLL 66
Query: 590 KQAKDGMLDLNKAAETLEV-QKRRIYDITNVLEGIDLIEKPFKNRILWKGVDTS-GPGDV 763
++AKDG+LDL AA+TL V QKRRIYDITNVLEGIDLIEK KN I WKGV +V
Sbjct: 67 QEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKEV 126
Query: 764 DADISVVQAEIENL 805
+ ++AEIE+L
Sbjct: 127 IDRLRYLKAEIEDL 140
>sp|O00716|E2F3_HUMAN Transcription factor E2F3 OS=Homo sapiens GN=E2F3 PE=1
SV=1
Length = 465
Score = 109 bits (271), Expect = 3e-023
Identities = 58/101 (57%), Positives = 70/101 (69%), Gaps = 1/101 (0%)
Frame = +2
Query: 506 SPPT-LTPSGSCRYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVL 682
SP T +PS RYD+SLGLLTKKF+ L+ Q+ DG+LDLNKAAE L+VQKRRIYDITNVL
Sbjct: 166 SPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVL 225
Query: 683 EGIDLIEKPFKNRILWKGVDTSGPGDVDADISVVQAEIENL 805
EGI LI+K KN + W G S G + A + E+ L
Sbjct: 226 EGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTEL 266
>sp|O35261|E2F3_MOUSE Transcription factor E2F3 OS=Mus musculus GN=E2f3 PE=1
SV=2
Length = 457
Score = 109 bits (271), Expect = 3e-023
Identities = 58/101 (57%), Positives = 70/101 (69%), Gaps = 1/101 (0%)
Frame = +2
Query: 506 SPPT-LTPSGSCRYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVL 682
SP T +PS RYD+SLGLLTKKF+ L+ Q+ DG+LDLNKAAE L+VQKRRIYDITNVL
Sbjct: 158 SPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVL 217
Query: 683 EGIDLIEKPFKNRILWKGVDTSGPGDVDADISVVQAEIENL 805
EGI LI+K KN + W G S G + A + E+ L
Sbjct: 218 EGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTEL 258
>sp|Q61502|E2F5_MOUSE Transcription factor E2F5 OS=Mus musculus GN=E2f5 PE=2
SV=1
Length = 335
Score = 107 bits (265), Expect = 1e-022
Identities = 64/124 (51%), Positives = 80/124 (64%), Gaps = 2/124 (1%)
Frame = +2
Query: 440 TKSKAKGNQSVPQTPISNAIVGSPPTLTPSGSCRYDSSLGLLTKKFVNLIKQAKDGMLDL 619
T S Q+ Q P A P + GS R++ SLGLLT KFV+L+++A+DG+LDL
Sbjct: 7 TSSAQPTPQAQAQPPPHGAPSSQPSRRSRGGSSRHEKSLGLLTTKFVSLLQEAQDGVLDL 66
Query: 620 NKAAETLEV-QKRRIYDITNVLEGIDLIEKPFKNRILWKGVDTS-GPGDVDADISVVQAE 793
AA+TL V QKRRIYDITNVLEGIDLIEK KN I WKGV +V + ++AE
Sbjct: 67 KAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKEVIDRLRCLKAE 126
Query: 794 IENL 805
IE+L
Sbjct: 127 IEDL 130
>sp|Q16254|E2F4_HUMAN Transcription factor E2F4 OS=Homo sapiens GN=E2F4 PE=1
SV=2
Length = 413
Score = 102 bits (254), Expect = 3e-021
Identities = 62/104 (59%), Positives = 75/104 (72%), Gaps = 11/104 (10%)
Frame = +2
Query: 509 PPTLTPSGSCRYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEV-QKRRIYDITNVLE 685
PP TPS R++ SLGLLT KFV+L+++AKDG+LDL AA+TL V QKRRIYDITNVLE
Sbjct: 10 PPPGTPS---RHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQKRRIYDITNVLE 66
Query: 686 GIDLIEKPFKNRILWKGVDTSGPG----DVDADISVVQAEIENL 805
GI LIEK KN I WKGV GPG ++ + ++AEIE L
Sbjct: 67 GIGLIEKKSKNSIQWKGV---GPGCNTREIADKLIELKAEIEEL 107
>sp|Q8R0K9|E2F4_MOUSE Transcription factor E2F4 OS=Mus musculus GN=E2f4 PE=2
SV=1
Length = 410
Score = 102 bits (254), Expect = 3e-021
Identities = 62/104 (59%), Positives = 75/104 (72%), Gaps = 11/104 (10%)
Frame = +2
Query: 509 PPTLTPSGSCRYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEV-QKRRIYDITNVLE 685
PP TPS R++ SLGLLT KFV+L+++AKDG+LDL AA+TL V QKRRIYDITNVLE
Sbjct: 10 PPPGTPS---RHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQKRRIYDITNVLE 66
Query: 686 GIDLIEKPFKNRILWKGVDTSGPG----DVDADISVVQAEIENL 805
GI LIEK KN I WKGV GPG ++ + ++AEIE L
Sbjct: 67 GIGLIEKKSKNSIQWKGV---GPGCNTREIADKLIELKAEIEEL 107
>sp|Q62814|E2F5_RAT Transcription factor E2F5 (Fragment) OS=Rattus norvegicus
GN=E2f5 PE=2 SV=1
Length = 300
Score = 102 bits (252), Expect = 5e-021
Identities = 57/94 (60%), Positives = 71/94 (75%), Gaps = 2/94 (2%)
Frame = +2
Query: 530 GSCRYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEV-QKRRIYDITNVLEGIDLIEK 706
GS R++ SLGLLT KFV+L+++A+DG+LDL AA+TL V QKRRIYDITNVLEGIDLIEK
Sbjct: 2 GSSRHEKSLGLLTTKFVSLLQEAQDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEK 61
Query: 707 PFKNRILWKGVDTS-GPGDVDADISVVQAEIENL 805
KN I WKGV +V + ++AEIE+L
Sbjct: 62 KSKNSIQWKGVGAGCNTKEVIDRLRCLKAEIEDL 95
>sp|Q14209|E2F2_HUMAN Transcription factor E2F2 OS=Homo sapiens GN=E2F2 PE=1
SV=1
Length = 437
Score = 99 bits (245), Expect = 3e-020
Identities = 51/78 (65%), Positives = 60/78 (76%), Gaps = 1/78 (1%)
Frame = +2
Query: 506 SPPT-LTPSGSCRYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVL 682
SP T +P RYD+SLGLLTKKF+ L+ +++DG+LDLN AAE L+VQKRRIYDITNVL
Sbjct: 117 SPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVL 176
Query: 683 EGIDLIEKPFKNRILWKG 736
EGI LI K KN I W G
Sbjct: 177 EGIQLIRKKAKNNIQWVG 194
>sp|P56931|E2F2_MOUSE Transcription factor E2F2 OS=Mus musculus GN=E2f2 PE=1
SV=2
Length = 443
Score = 99 bits (245), Expect = 3e-020
Identities = 51/78 (65%), Positives = 60/78 (76%), Gaps = 1/78 (1%)
Frame = +2
Query: 506 SPPT-LTPSGSCRYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVL 682
SP T +P RYD+SLGLLTKKF+ L+ +++DG+LDLN AAE L+VQKRRIYDITNVL
Sbjct: 119 SPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVL 178
Query: 683 EGIDLIEKPFKNRILWKG 736
EGI LI K KN I W G
Sbjct: 179 EGIQLIRKKSKNNIQWVG 196
>sp|Q27368|E2F_DROME Transcription factor E2f OS=Drosophila melanogaster GN=E2f
PE=1 SV=2
Length = 805
Score = 91 bits (224), Expect = 8e-018
Identities = 45/89 (50%), Positives = 65/89 (73%), Gaps = 3/89 (3%)
Frame = +2
Query: 467 SVPQTPISNAIVGSPPTLTPSGSCRYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEV 646
S PQ ++ ++ S + R D+SLG+LTKKFV+L++++ DG++DLN+A+ L V
Sbjct: 233 STPQQQLAASVASSS---SSGDRNRADTSLGILTKKFVDLLQESPDGVVDLNEASNRLHV 289
Query: 647 QKRRIYDITNVLEGIDLIEKPFKNRILWK 733
QKRRIYDITNVLEGI+++EK KN I W+
Sbjct: 290 QKRRIYDITNVLEGINILEKKSKNNIQWR 318
>sp|Q90977|E2F1_CHICK Transcription factor E2F1 OS=Gallus gallus GN=E2F1 PE=2
SV=1
Length = 403
Score = 90 bits (222), Expect = 1e-017
Identities = 44/72 (61%), Positives = 54/72 (75%)
Frame = +2
Query: 521 TPSGSCRYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVLEGIDLI 700
+P RY++SL L TK+F+ L+ Q+ DG++DLN AAE L+VQKRRIYDITNVLEGI LI
Sbjct: 98 SPGEKSRYETSLNLTTKRFLELLSQSPDGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLI 157
Query: 701 EKPFKNRILWKG 736
K KN I W G
Sbjct: 158 TKKSKNNIQWLG 169
>sp|Q01094|E2F1_HUMAN Transcription factor E2F1 OS=Homo sapiens GN=E2F1 PE=1
SV=1
Length = 437
Score = 89 bits (220), Expect = 2e-017
Identities = 44/76 (57%), Positives = 55/76 (72%)
Frame = +2
Query: 521 TPSGSCRYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVLEGIDLI 700
+P RY++SL L TK+F+ L+ + DG++DLN AAE L+VQKRRIYDITNVLEGI LI
Sbjct: 121 SPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLI 180
Query: 701 EKPFKNRILWKGVDTS 748
K KN I W G T+
Sbjct: 181 AKKSKNHIQWLGSHTT 196
>sp|Q61501|E2F1_MOUSE Transcription factor E2F1 OS=Mus musculus GN=E2f1 PE=1
SV=1
Length = 430
Score = 89 bits (220), Expect = 2e-017
Identities = 44/75 (58%), Positives = 55/75 (73%)
Frame = +2
Query: 521 TPSGSCRYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVLEGIDLI 700
+P RY++SL L TK+F+ L+ ++ DG++DLN AAE L+VQKRRIYDITNVLEGI LI
Sbjct: 116 SPGEKSRYETSLNLTTKRFLELLSRSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLI 175
Query: 701 EKPFKNRILWKGVDT 745
K KN I W G T
Sbjct: 176 AKKSKNHIQWLGSHT 190
>sp|Q08DY6|E2F6_BOVIN Transcription factor E2F6 OS=Bos taurus GN=E2F6 PE=2 SV=1
Length = 285
Score = 88 bits (217), Expect = 5e-017
Identities = 47/89 (52%), Positives = 61/89 (68%), Gaps = 1/89 (1%)
Frame = +2
Query: 539 RYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVLEGIDLIEKPFKN 718
R+D SL LT+KF++L++ A G+LDLNK A L V+KRR+YDITNVL+GIDL+EK KN
Sbjct: 63 RFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIDLVEKKSKN 122
Query: 719 RILWKGVDTSGPGDVDADISVVQAEIENL 805
I W G D S G V +Q E+ +L
Sbjct: 123 HIRWIGSDLSNFGAVPQQ-KKLQEELSDL 150
>sp|O75461|E2F6_HUMAN Transcription factor E2F6 OS=Homo sapiens GN=E2F6 PE=1
SV=1
Length = 281
Score = 88 bits (217), Expect = 5e-017
Identities = 47/89 (52%), Positives = 61/89 (68%), Gaps = 1/89 (1%)
Frame = +2
Query: 539 RYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVLEGIDLIEKPFKN 718
R+D SL LT+KF++L++ A G+LDLNK A L V+KRR+YDITNVL+GIDL+EK KN
Sbjct: 63 RFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIDLVEKKSKN 122
Query: 719 RILWKGVDTSGPGDVDADISVVQAEIENL 805
I W G D S G V +Q E+ +L
Sbjct: 123 HIRWIGSDLSNFGAVPQQ-KKLQEELSDL 150
>sp|O54917|E2F6_MOUSE Transcription factor E2F6 OS=Mus musculus GN=E2f6 PE=1
SV=1
Length = 272
Score = 87 bits (213), Expect = 2e-016
Identities = 45/89 (50%), Positives = 61/89 (68%), Gaps = 1/89 (1%)
Frame = +2
Query: 539 RYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVLEGIDLIEKPFKN 718
R+D SL LT+KF++L++ A G+LDLNK A L V+KRR+YDITNVL+GI+L+EK KN
Sbjct: 63 RFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLSVRKRRVYDITNVLDGIELVEKKSKN 122
Query: 719 RILWKGVDTSGPGDVDADISVVQAEIENL 805
I W G D + G +QAE+ +L
Sbjct: 123 HIRWIGSDLNNFGAAPQQ-KKLQAELSDL 150
>sp|O09139|E2F1_RAT Transcription factor E2F1 (Fragment) OS=Rattus norvegicus
GN=E2f1 PE=1 SV=1
Length = 38
Score = 56 bits (133), Expect = 3e-007
Identities = 26/38 (68%), Positives = 32/38 (84%)
Frame = +2
Query: 575 FVNLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVLEG 688
F+ L+ + DG++DLN AAE L+VQKRRIYDITNVLEG
Sbjct: 1 FLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEG 38
>sp|A0AVK6|E2F8_HUMAN Transcription factor E2F8 OS=Homo sapiens GN=E2F8 PE=1
SV=1
Length = 867
Score = 55 bits (131), Expect = 5e-007
Identities = 30/70 (42%), Positives = 42/70 (60%), Gaps = 4/70 (5%)
Frame = +2
Query: 539 RYDSSLGLLTKKFV----NLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVLEGIDLIEK 706
R + SLGLL KF+ N A + + L++ AE L V++RRIYDI NVLE + ++ +
Sbjct: 113 RKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSR 172
Query: 707 PFKNRILWKG 736
KNR W G
Sbjct: 173 LAKNRYTWHG 182
>sp|Q58FA4|E2F8_MOUSE Transcription factor E2F8 OS=Mus musculus GN=E2f8 PE=1
SV=1
Length = 860
Score = 53 bits (125), Expect = 2e-006
Identities = 29/70 (41%), Positives = 41/70 (58%), Gaps = 4/70 (5%)
Frame = +2
Query: 539 RYDSSLGLLTKKFV----NLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVLEGIDLIEK 706
R + SLGLL KF+ A + + L++ AE L V++RRIYDI NVLE + ++ +
Sbjct: 113 RKEKSLGLLCHKFLARYPKYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSR 172
Query: 707 PFKNRILWKG 736
KNR W G
Sbjct: 173 LAKNRYTWHG 182
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 262,776,655,547
Number of Sequences: 518415
Number of Extensions: 262776655547
Number of Successful Extensions: 1686502940
Number of sequences better than 0.0: 0
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