BLASTX 7.6.2
Query= UN82659 /QuerySize=598
(597 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q05047|C72A1_CATRO Secologanin synthase OS=Catharanthus roseu... 134 4e-031
sp|Q27519|C13A7_CAEEL Putative cytochrome P450 CYP13A7 OS=Caenor... 69 1e-011
sp|P59954|CP132_MYCBO Putative cytochrome P450 132 OS=Mycobacter... 69 1e-011
sp|P77900|CP132_MYCTU Putative cytochrome P450 132 OS=Mycobacter... 69 1e-011
sp|Q27514|C13A5_CAEEL Putative cytochrome P450 CYP13A5 OS=Caenor... 68 3e-011
sp|P14779|CPXB_BACME Bifunctional P-450/NADPH-P450 reductase OS=... 68 3e-011
sp|Q27515|C13A6_CAEEL Putative cytochrome P450 CYP13A6 OS=Caenor... 63 1e-009
sp|Q27520|C13A1_CAEEL Putative cytochrome P450 CYP13A1 OS=Caenor... 62 3e-009
sp|P15129|CP4B1_RAT Cytochrome P450 4B1 OS=Rattus norvegicus GN=... 58 4e-008
sp|Q9Y6A2|CP46A_HUMAN Cholesterol 24-hydroxylase OS=Homo sapiens... 57 6e-008
sp|Q9WVK8|CP46A_MOUSE Cholesterol 24-hydroxylase OS=Mus musculus... 57 6e-008
sp|P13584|CP4B1_HUMAN Cytochrome P450 4B1 OS=Homo sapiens GN=CYP... 55 2e-007
sp|Q86W10|CP4Z1_HUMAN Cytochrome P450 4Z1 OS=Homo sapiens GN=CYP... 54 5e-007
sp|Q64462|CP4B1_MOUSE Cytochrome P450 4B1 OS=Mus musculus GN=Cyp... 54 8e-007
sp|Q9VYT8|C28C1_DROME Probable cytochrome P450 28c1 OS=Drosophil... 53 1e-006
sp|O81974|C71D8_SOYBN Cytochrome P450 71D8 OS=Glycine max GN=CYP... 52 3e-006
sp|Q59990|CP120_SYNY3 Putative cytochrome P450 120 OS=Synechocys... 51 4e-006
sp|Q7X7X4|C99A2_ORYSJ Cytochrome P450 99A2 OS=Oryza sativa subsp... 50 9e-006
>sp|Q05047|C72A1_CATRO Secologanin synthase OS=Catharanthus roseus GN=CYP72A1
PE=2 SV=1
Length = 524
Score = 134 bits (337), Expect = 4e-031
Identities = 55/97 (56%), Positives = 77/97 (79%)
Frame = +3
Query: 15 LVHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMA 194
++HR+ +WGEDA EF P RF +G++ ATKN V Y PF WG R+C+GQNF+L +AK+ +A
Sbjct: 426 MLHREKSIWGEDAMEFNPMRFVDGVANATKNNVTYLPFSWGPRVCLGQNFALLQAKLGLA 485
Query: 195 LILQRFSFELSPSYVHAPQIVMTTRPQFGAHLILHKL 305
+ILQRF F+++PSYVHAP ++T +PQFG+H+I KL
Sbjct: 486 MILQRFKFDVAPSYVHAPFTILTVQPQFGSHVIYKKL 522
>sp|Q27519|C13A7_CAEEL Putative cytochrome P450 CYP13A7 OS=Caenorhabditis
elegans GN=cyp-13A7 PE=2 SV=1
Length = 518
Score = 69 bits (168), Expect = 1e-011
Identities = 34/82 (41%), Positives = 50/82 (60%), Gaps = 1/82 (1%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMAL 197
+H D K+WG+D EFKPER++ G + + Y PFG G RICIG ++ E KM +
Sbjct: 422 LHHDPKVWGDDVNEFKPERWESG-DELFFAKGGYLPFGMGPRICIGMRLAMMEMKMLLTN 480
Query: 198 ILQRFSFELSPSYVHAPQIVMT 263
IL+ ++FE +P V ++V T
Sbjct: 481 ILKNYTFETTPETVIPLKLVGT 502
>sp|P59954|CP132_MYCBO Putative cytochrome P450 132 OS=Mycobacterium bovis
GN=cyp132 PE=3 SV=1
Length = 461
Score = 69 bits (168), Expect = 1e-011
Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 3/92 (3%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMAL 197
+H D + W D F P RF + + Y PFG G RICIGQ+F+L E + A+
Sbjct: 369 IHHDPR-WWPDPDRFDPGRFLR--CPTDRPRCAYLPFGGGRRICIGQSFALMEMVLMAAI 425
Query: 198 ILQRFSFELSPSYVHAPQIVMTTRPQFGAHLI 293
+ Q F+F+L+P Y + +T RP+ G H+I
Sbjct: 426 MSQHFTFDLAPGYHVELEATLTLRPKHGVHVI 457
>sp|P77900|CP132_MYCTU Putative cytochrome P450 132 OS=Mycobacterium
tuberculosis GN=cyp132 PE=3 SV=1
Length = 461
Score = 69 bits (168), Expect = 1e-011
Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 3/92 (3%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMAL 197
+H D + W D F P RF + + Y PFG G RICIGQ+F+L E + A+
Sbjct: 369 IHHDPR-WWPDPDRFDPGRFLR--CPTDRPRCAYLPFGGGRRICIGQSFALMEMVLMAAI 425
Query: 198 ILQRFSFELSPSYVHAPQIVMTTRPQFGAHLI 293
+ Q F+F+L+P Y + +T RP+ G H+I
Sbjct: 426 MSQHFTFDLAPGYHVELEATLTLRPKHGVHVI 457
>sp|Q27514|C13A5_CAEEL Putative cytochrome P450 CYP13A5 OS=Caenorhabditis
elegans GN=cyp-13A5 PE=2 SV=1
Length = 520
Score = 68 bits (165), Expect = 3e-011
Identities = 32/70 (45%), Positives = 46/70 (65%), Gaps = 1/70 (1%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMAL 197
+H D K+WGEDA EF+PER++ G + + Y PFG G RICIG ++ E KM +
Sbjct: 422 LHYDPKVWGEDANEFRPERWESG-DELFYAKGGYLPFGMGPRICIGMRLAMMEKKMLLTH 480
Query: 198 ILQRFSFELS 227
IL++++FE S
Sbjct: 481 ILKKYTFETS 490
>sp|P14779|CPXB_BACME Bifunctional P-450/NADPH-P450 reductase OS=Bacillus
megaterium GN=CYP102A1 PE=1 SV=2
Length = 1049
Score = 68 bits (165), Expect = 3e-011
Identities = 33/86 (38%), Positives = 52/86 (60%), Gaps = 3/86 (3%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMAL 197
+HRD +WG+D EF+PERF+ + + Q + PFG G R CIGQ F+L EA + + +
Sbjct: 361 LHRDKTIWGDDVEEFRPERFE---NPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGM 417
Query: 198 ILQRFSFELSPSYVHAPQIVMTTRPQ 275
+L+ F FE +Y + +T +P+
Sbjct: 418 MLKHFDFEDHTNYELDIKETLTLKPE 443
>sp|Q27515|C13A6_CAEEL Putative cytochrome P450 CYP13A6 OS=Caenorhabditis
elegans GN=cyp-13A6 PE=2 SV=1
Length = 518
Score = 63 bits (152), Expect = 1e-009
Identities = 27/67 (40%), Positives = 42/67 (62%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMAL 197
+H + ++WGED +FKPER++ G + ++ Y PFG G R CIG + E K+ +A
Sbjct: 420 LHHNPRIWGEDVEDFKPERWENGACEHLEHNGSYIPFGSGPRQCIGMRLAQMEQKILLAQ 479
Query: 198 ILQRFSF 218
IL+ +SF
Sbjct: 480 ILKEYSF 486
>sp|Q27520|C13A1_CAEEL Putative cytochrome P450 CYP13A1 OS=Caenorhabditis
elegans GN=cyp-13A1 PE=2 SV=1
Length = 519
Score = 62 bits (148), Expect = 3e-009
Identities = 28/68 (41%), Positives = 41/68 (60%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMAL 197
+H D +WG+DA +FKPER++ S + Y PFG G R CIG + E K+ +
Sbjct: 422 LHTDPNIWGDDAEDFKPERWQTPNSDQIYQKSGYIPFGLGPRQCIGMRLAYMEEKILLVH 481
Query: 198 ILQRFSFE 221
IL++F+FE
Sbjct: 482 ILRKFTFE 489
>sp|P15129|CP4B1_RAT Cytochrome P450 4B1 OS=Rattus norvegicus GN=Cyp4b1 PE=1
SV=3
Length = 511
Score = 58 bits (138), Expect = 4e-008
Identities = 37/98 (37%), Positives = 53/98 (54%), Gaps = 6/98 (6%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMAL 197
+HR++ +W D F P RF + A ++ + PF G R CIGQ F++ E K+ AL
Sbjct: 412 LHRNSTVW-PDPEVFDPLRFSPE-NAAGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTAL 469
Query: 198 ILQRFSFELSPSY--VHAPQIVMTTRPQFGAHLILHKL 305
L RF F L PS + PQ+++ R + G HL L L
Sbjct: 470 CLLRFEFSLDPSKMPIKVPQLIL--RSKNGIHLYLKPL 505
>sp|Q9Y6A2|CP46A_HUMAN Cholesterol 24-hydroxylase OS=Homo sapiens GN=CYP46A1
PE=1 SV=1
Length = 500
Score = 57 bits (137), Expect = 6e-008
Identities = 33/76 (43%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Frame = +3
Query: 45 EDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMALILQRFSFEL 224
ED F P+RF G A K + YFPF G R CIGQ F+ E K+ MA +LQR F L
Sbjct: 406 EDPLTFNPDRFGPG---APKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRL 462
Query: 225 SPSYVHAPQIVMTTRP 272
P Q T +P
Sbjct: 463 VPGQRFGLQEQATLKP 478
>sp|Q9WVK8|CP46A_MOUSE Cholesterol 24-hydroxylase OS=Mus musculus GN=Cyp46a1
PE=2 SV=1
Length = 500
Score = 57 bits (137), Expect = 6e-008
Identities = 33/76 (43%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Frame = +3
Query: 45 EDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMALILQRFSFEL 224
ED F P+RF G A K + YFPF G R CIGQ F+ E K+ MA +LQR F L
Sbjct: 406 EDPLTFNPDRFGPG---APKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRL 462
Query: 225 SPSYVHAPQIVMTTRP 272
P Q T +P
Sbjct: 463 VPGQRFGLQEQATLKP 478
>sp|P13584|CP4B1_HUMAN Cytochrome P450 4B1 OS=Homo sapiens GN=CYP4B1 PE=1 SV=2
Length = 511
Score = 55 bits (132), Expect = 2e-007
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 6/94 (6%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFK-EGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMA 194
+HR++ +W D F RF E SK ++ + PF G R CIGQ F++ E K+ A
Sbjct: 412 LHRNSAVW-PDPEVFDSLRFSTENASK--RHPFAFMPFSAGPRNCIGQQFAMSEMKVVTA 468
Query: 195 LILQRFSFELSPSY--VHAPQIVMTTRPQFGAHL 290
+ L RF F L PS + PQ+V+ ++ F HL
Sbjct: 469 MCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 502
>sp|Q86W10|CP4Z1_HUMAN Cytochrome P450 4Z1 OS=Homo sapiens GN=CYP4Z1 PE=2 SV=1
Length = 505
Score = 54 bits (129), Expect = 5e-007
Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 6/98 (6%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMAL 197
+H + W ED F P RF S+ + + PF GLR CIGQ+F++ E K+A+AL
Sbjct: 411 LHHNPYFW-EDPQVFNPLRFSRENSEKI-HPYAFIPFSAGLRNCIGQHFAIIECKVAVAL 468
Query: 198 ILQRFSFELSPSYVHAPQIV--MTTRPQFGAHLILHKL 305
L R F+L+P + PQ V + + + G H+ K+
Sbjct: 469 TLLR--FKLAPDHSRPPQPVRQVVLKSKNGIHVFAKKV 504
>sp|Q64462|CP4B1_MOUSE Cytochrome P450 4B1 OS=Mus musculus GN=Cyp4b1 PE=1 SV=1
Length = 511
Score = 54 bits (127), Expect = 8e-007
Identities = 35/98 (35%), Positives = 51/98 (52%), Gaps = 6/98 (6%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMAL 197
+HR++ +W D F P RF + ++ + PF G R CIGQ F++ E K+ AL
Sbjct: 412 LHRNSAVW-PDPEVFDPLRFSPE-NMTGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTAL 469
Query: 198 ILQRFSFELSPSY--VHAPQIVMTTRPQFGAHLILHKL 305
L RF F PS + PQ+++ R + G HL L L
Sbjct: 470 CLLRFEFSPDPSKIPIKVPQLIL--RSKNGIHLYLKPL 505
>sp|Q9VYT8|C28C1_DROME Probable cytochrome P450 28c1 OS=Drosophila melanogaster
GN=Cyp28c1 PE=2 SV=1
Length = 505
Score = 53 bits (126), Expect = 1e-006
Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMAL 197
+H D L+ E F+PERF +G K K Q + FG G R C+G L AK A+A
Sbjct: 402 LHNDPDLYPE-PDVFRPERFLDGGLKNCKQQGIFLGFGNGPRQCVGMRLGLAMAKAALAA 460
Query: 198 ILQRFSFELSPSYVHAPQI 254
I+QRF +SP ++ ++
Sbjct: 461 IVQRFEVVVSPRTLNGTEL 479
>sp|O81974|C71D8_SOYBN Cytochrome P450 71D8 OS=Glycine max GN=CYP71D8 PE=2 SV=1
Length = 504
Score = 52 bits (122), Expect = 3e-006
Identities = 27/69 (39%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Frame = +3
Query: 18 VHRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMAL 197
+ RD + W DA F PERF + N Y PFG G R+C G F L + +AL
Sbjct: 402 IGRDPQYW-SDADRFIPERFNDSSIDFKGNSFEYIPFGAGRRMCPGMTFGLASITLPLAL 460
Query: 198 ILQRFSFEL 224
+L F++EL
Sbjct: 461 LLYHFNWEL 469
>sp|Q59990|CP120_SYNY3 Putative cytochrome P450 120 OS=Synechocystis sp. (strain
PCC 6803) GN=cyp120 PE=1 SV=1
Length = 444
Score = 51 bits (121), Expect = 4e-006
Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Frame = +3
Query: 21 HRDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMALI 200
H D L+ D +F PERF S + PFG GLR C+G+ F+ E K+ +
Sbjct: 350 HADPDLY-PDPEKFDPERFTPDGSATHNPPFAHVPFGGGLRECLGKEFARLEMKLFATRL 408
Query: 201 LQRFSFELSPSYVHAPQIVMTTRPQFGAHLILHKL 305
+Q+F + L P + + RP+ + LH L
Sbjct: 409 IQQFDWTLLPGQNLELVVTPSPRPKDNLRVKLHSL 443
>sp|Q7X7X4|C99A2_ORYSJ Cytochrome P450 99A2 OS=Oryza sativa subsp. japonica
GN=CYP99A2 PE=2 SV=2
Length = 532
Score = 50 bits (118), Expect = 9e-006
Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
Frame = +3
Query: 24 RDTKLWGEDAGEFKPERFKEGISKATKNQVCYFPFGWGLRICIGQNFSLFEAKMAMALIL 203
R + W +DA EFKPERF++G++ ++ Y PFG G R C G F + ++ +A +L
Sbjct: 428 RSPEYW-DDAEEFKPERFEDGMADYKGSRFEYLPFGTGRRRCPGDTFGMVLLELIVARLL 486
Query: 204 QRFSFEL 224
F + L
Sbjct: 487 YYFDWSL 493
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 262,776,655,547
Number of Sequences: 518415
Number of Extensions: 262776655547
Number of Successful Extensions: 1686502940
Number of sequences better than 0.0: 0
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