BLASTX 7.6.2
Query= UN82820 /QuerySize=863
(862 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=R... 97 2e-019
sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN... 95 6e-019
sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN... 95 6e-019
sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 94 1e-018
sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 92 3e-018
sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 91 7e-018
sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo... 91 9e-018
sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus ... 91 1e-017
sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabido... 73 2e-012
sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus ... 71 7e-012
sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus... 69 3e-011
sp|Q5M974|RN181_XENTR E3 ubiquitin-protein ligase RNF181 OS=Xeno... 69 3e-011
sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos ... 68 8e-011
sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Dani... 68 8e-011
sp|Q6GPV5|RN181_XENLA E3 ubiquitin-protein ligase RNF181 OS=Xeno... 67 1e-010
sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabido... 67 2e-010
sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo... 66 2e-010
sp|Q9C1X4|YKW3_SCHPO Uncharacterized RING finger protein P32A8.0... 65 4e-010
sp|Q8VEM1|GOLI_MOUSE Goliath homolog OS=Mus musculus GN=Rnf130 P... 55 4e-007
sp|Q6Y290|GOLI_RAT Goliath homolog OS=Rattus norvegicus GN=Rnf13... 55 4e-007
>sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=RNF126 PE=2
SV=1
Length = 313
Score = 97 bits (239), Expect = 2e-019
Identities = 49/111 (44%), Positives = 69/111 (62%), Gaps = 8/111 (7%)
Frame = +3
Query: 537 TSPGIGIARGG--NTNAGDYFYGP-GLEELIEQLSSSGGTTTHHRGPPPAAKSSIDALPT 707
T P +G+ G ++N DY +G GL+ +I QL + T GPPPA K I ALPT
Sbjct: 163 TIPNLGLGPWGVLHSNPMDYAWGANGLDAIITQLLNQFENT----GPPPADKEKIQALPT 218
Query: 708 VKITQKHLKSSDSHCPVCKDEFELKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
V +T++H+ S CPVCKD++ L +Q+PC H++H CIVPWL QH++
Sbjct: 219 VPVTEEHV-GSGLECPVCKDDYGLGEHVRQLPCNHLFHDGCIVPWLEQHDS 268
>sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN=RNF126 PE=1
SV=1
Length = 326
Score = 95 bits (234), Expect = 6e-019
Identities = 48/109 (44%), Positives = 67/109 (61%), Gaps = 6/109 (5%)
Frame = +3
Query: 537 TSPGIGIARGGNTNAGDYFYGP-GLEELIEQLSSSGGTTTHHRGPPPAAKSSIDALPTVK 713
T P +G ++N DY +G GL+ +I QL + T GPPPA K I ALPTV
Sbjct: 162 TIPSLGPWGVLHSNPMDYAWGANGLDAIITQLLNQFENT----GPPPADKEKIQALPTVP 217
Query: 714 ITQKHLKSSDSHCPVCKDEFELKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
+T++H+ S CPVCKD++ L +Q+PC H++H CIVPWL QH++
Sbjct: 218 VTEEHV-GSGLECPVCKDDYALGERVRQLPCNHLFHDGCIVPWLEQHDS 265
>sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN=Rnf126 PE=1
SV=1
Length = 313
Score = 95 bits (234), Expect = 6e-019
Identities = 47/109 (43%), Positives = 68/109 (62%), Gaps = 8/109 (7%)
Frame = +3
Query: 543 PGIGIARGG--NTNAGDYFYGP-GLEELIEQLSSSGGTTTHHRGPPPAAKSSIDALPTVK 713
P +G+ G ++N DY +G GL+ +I QL + T GPPPA K I ALPTV
Sbjct: 164 PSLGLGPWGVLHSNPMDYAWGANGLDTIITQLLNQFENT----GPPPADKEKIQALPTVP 219
Query: 714 ITQKHLKSSDSHCPVCKDEFELKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
+T++H+ S CPVCK+++ L +Q+PC H++H CIVPWL QH++
Sbjct: 220 VTEEHV-GSGLECPVCKEDYALGESVRQLPCNHLFHDSCIVPWLEQHDS 267
>sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126
PE=2 SV=1
Length = 311
Score = 94 bits (231), Expect = 1e-018
Identities = 43/98 (43%), Positives = 65/98 (66%), Gaps = 6/98 (6%)
Frame = +3
Query: 570 NTNAGDYFYGP-GLEELIEQLSSSGGTTTHHRGPPPAAKSSIDALPTVKITQKHLKSSDS 746
++N DY +G GL+ +I QL + T GPPPA I ALPT++IT++H+ S
Sbjct: 171 HSNPMDYAWGANGLDTIITQLLNQFENT----GPPPADTEKIQALPTIQITEEHV-GSGL 225
Query: 747 HCPVCKDEFELKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
CPVCK+++ + +Q+PC H++H+DCI+PWL QH+T
Sbjct: 226 ECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDT 263
>sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-a
PE=2 SV=1
Length = 312
Score = 92 bits (228), Expect = 3e-018
Identities = 43/98 (43%), Positives = 65/98 (66%), Gaps = 6/98 (6%)
Frame = +3
Query: 570 NTNAGDYFYGP-GLEELIEQLSSSGGTTTHHRGPPPAAKSSIDALPTVKITQKHLKSSDS 746
++N DY +G GL+ +I QL + T GPPPA I ALPT++IT++H+ S
Sbjct: 172 HSNPMDYAWGANGLDTIITQLLNQFENT----GPPPADNEKIQALPTIQITEEHV-GSGL 226
Query: 747 HCPVCKDEFELKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
CPVCK+++ + +Q+PC H++H+DCI+PWL QH+T
Sbjct: 227 ECPVCKEDYTVGECVRQLPCNHLFHNDCIIPWLEQHDT 264
>sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-b
PE=2 SV=1
Length = 312
Score = 91 bits (225), Expect = 7e-018
Identities = 42/98 (42%), Positives = 64/98 (65%), Gaps = 6/98 (6%)
Frame = +3
Query: 570 NTNAGDYFYGP-GLEELIEQLSSSGGTTTHHRGPPPAAKSSIDALPTVKITQKHLKSSDS 746
++N DY +G GL+ +I QL + T GPPPA I ALPT++IT++H+
Sbjct: 172 HSNPMDYAWGANGLDTIITQLLNQFENT----GPPPADTDKIQALPTIQITEEHV-GFGL 226
Query: 747 HCPVCKDEFELKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
CPVCK+++ + +Q+PC H++H+DCI+PWL QH+T
Sbjct: 227 ECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDT 264
>sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo sapiens
GN=RNF115 PE=1 SV=2
Length = 304
Score = 91 bits (224), Expect = 9e-018
Identities = 42/98 (42%), Positives = 62/98 (63%), Gaps = 6/98 (6%)
Frame = +3
Query: 570 NTNAGDYFYG-PGLEELIEQLSSSGGTTTHHRGPPPAAKSSIDALPTVKITQKHLKSSDS 746
++N GDY +G GL+ ++ QL + GPPPA K I +LPTV +TQ+ +
Sbjct: 172 HSNPGDYAWGQTGLDAIVTQLLGQ----LENTGPPPADKEKITSLPTVTVTQEQV-DMGL 226
Query: 747 HCPVCKDEFELKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
CPVCK+++ ++ E +Q+PC H +HS CIVPWL H+T
Sbjct: 227 ECPVCKEDYTVEEEVRQLPCNHFFHSSCIVPWLELHDT 264
>sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus musculus
GN=Rnf115 PE=1 SV=1
Length = 305
Score = 91 bits (223), Expect = 1e-017
Identities = 41/98 (41%), Positives = 64/98 (65%), Gaps = 6/98 (6%)
Frame = +3
Query: 570 NTNAGDYFYG-PGLEELIEQLSSSGGTTTHHRGPPPAAKSSIDALPTVKITQKHLKSSDS 746
++N GDY +G GL+ ++ QL + GPPPA K I +LPTV +TQ+ + ++
Sbjct: 173 HSNPGDYAWGQTGLDAIVTQLLGQ----LENTGPPPADKEKITSLPTVTVTQEQV-NTGL 227
Query: 747 HCPVCKDEFELKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
CPVCK+++ ++ + +Q+PC H +HS CIVPWL H+T
Sbjct: 228 ECPVCKEDYTVEEKVRQLPCNHFFHSSCIVPWLELHDT 265
>sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabidopsis thaliana
GN=CIP8 PE=1 SV=1
Length = 334
Score = 73 bits (178), Expect = 2e-012
Identities = 42/101 (41%), Positives = 55/101 (54%), Gaps = 11/101 (10%)
Frame = +3
Query: 576 NAGDYF-YGPGLEELIEQLS-SSGGTTTHHRGPPPAAKSSIDALPTVKITQKHLKSSDSH 749
N DY G E L++ L+ GG RG PPAAKS+I+AL T +++ SS+
Sbjct: 198 NPADYIDDAAGYEALLQNLAEGDGGGGGGRRGAPPAAKSAIEALETFEVS-----SSEGE 252
Query: 750 ----CPVCKDEFELKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
C VCKD + K++PC H YH DCIVPWL N+
Sbjct: 253 MVMVCAVCKDGMVMGETGKKLPCGHCYHGDCIVPWLGTRNS 293
>sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus musculus
GN=Rnf181 PE=2 SV=1
Length = 165
Score = 71 bits (173), Expect = 7e-012
Identities = 35/95 (36%), Positives = 53/95 (55%), Gaps = 5/95 (5%)
Frame = +3
Query: 582 GDYFYGPGLEELIEQL--SSSGGTTTHHRGPPPAAKSSIDALPTVKITQKHLKSSDSHCP 755
G + + PG L ++ G H PPPAAK+ +++LP I+ +D CP
Sbjct: 33 GAWSWAPGGRSLFNRMDFEDLGLVDWEHHLPPPAAKAVVESLPRTVISS---AKADLKCP 89
Query: 756 VCKDEFELKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
VC EFE + +MPC H++HS+CI+PWL + N+
Sbjct: 90 VCLLEFEAEETVIEMPCHHLFHSNCILPWLSKTNS 124
>sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus norvegicus
GN=Rnf181 PE=1 SV=1
Length = 165
Score = 69 bits (168), Expect = 3e-011
Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +3
Query: 582 GDYFYGPGLEELIEQL--SSSGGTTTHHRGPPPAAKSSIDALPTVKITQKHLKSSDSHCP 755
G + + PG L ++ G H PPPAAK+ +++LP I ++ CP
Sbjct: 33 GAWSWAPGSRSLFNRMDFEDLGLVDWEHHLPPPAAKAVVESLPRTVIRS---SKAELKCP 89
Query: 756 VCKDEFELKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
VC EFE + +MPC H++HS+CI+PWL + N+
Sbjct: 90 VCLLEFEEEETVIEMPCHHLFHSNCILPWLSKTNS 124
>sp|Q5M974|RN181_XENTR E3 ubiquitin-protein ligase RNF181 OS=Xenopus tropicalis
GN=rnf181 PE=2 SV=1
Length = 156
Score = 69 bits (168), Expect = 3e-011
Identities = 31/72 (43%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = +3
Query: 645 TTTHHRGPPPAAKSSIDALPTVKITQKHLKSSDSHCPVCKDEFELKSEAKQMPCKHVYHS 824
T R PPPAAK +++LP V +T + ++ CPVC EFE +Q+PC+H++HS
Sbjct: 45 TEWDQRLPPPAAKKVVESLPKVTVTPEQADAA-LKCPVCLLEFEEGETVRQLPCEHLFHS 103
Query: 825 DCIVPWLVQHNT 860
CI+PWL + N+
Sbjct: 104 SCILPWLGKTNS 115
>sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos taurus
GN=RNF181 PE=2 SV=1
Length = 153
Score = 68 bits (164), Expect = 8e-011
Identities = 32/70 (45%), Positives = 47/70 (67%), Gaps = 7/70 (10%)
Frame = +3
Query: 657 HRGPPPAAKSSIDALP--TVKITQKHLKSSDSHCPVCKDEFELKSEAKQMPCKHVYHSDC 830
H PPPAAK++++ LP ++ +Q LK CPVC EFE + A +MPC H++HS+C
Sbjct: 48 HHLPPPAAKTAVENLPRTVIRGSQAELK-----CPVCLLEFEEEETAIEMPCHHLFHSNC 102
Query: 831 IVPWLVQHNT 860
I+PWL + N+
Sbjct: 103 ILPWLSKTNS 112
>sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Danio rerio
GN=rnf181 PE=2 SV=2
Length = 156
Score = 68 bits (164), Expect = 8e-011
Identities = 30/67 (44%), Positives = 44/67 (65%), Gaps = 1/67 (1%)
Frame = +3
Query: 660 RGPPPAAKSSIDALPTVKITQKHLKSSDSHCPVCKDEFELKSEAKQMPCKHVYHSDCIVP 839
R PPPAAK+ + +LP V I+ + CPVC EFE + ++MPCKH++H+ CI+P
Sbjct: 50 RLPPPAAKAVVQSLPVVIISPEQ-ADKGVKCPVCLLEFEEQESVREMPCKHLFHTGCILP 108
Query: 840 WLVQHNT 860
WL + N+
Sbjct: 109 WLNKTNS 115
>sp|Q6GPV5|RN181_XENLA E3 ubiquitin-protein ligase RNF181 OS=Xenopus laevis
GN=rnf181 PE=2 SV=1
Length = 156
Score = 67 bits (163), Expect = 1e-010
Identities = 30/72 (41%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = +3
Query: 645 TTTHHRGPPPAAKSSIDALPTVKITQKHLKSSDSHCPVCKDEFELKSEAKQMPCKHVYHS 824
T R PPPA+K +++LP V +T + ++ CPVC EFE +Q+PC+H++HS
Sbjct: 45 TEWDQRLPPPASKKVVESLPKVTVTPEQADAA-LKCPVCLLEFEEGETVRQLPCEHLFHS 103
Query: 825 DCIVPWLVQHNT 860
CI+PWL + N+
Sbjct: 104 ACILPWLGKTNS 115
>sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabidopsis thaliana
GN=AIP2 PE=1 SV=1
Length = 310
Score = 67 bits (161), Expect = 2e-010
Identities = 28/88 (31%), Positives = 51/88 (57%), Gaps = 6/88 (6%)
Frame = +3
Query: 603 GLEELIEQLSSSGGTTTHHRGPPPAAKSSIDALPTVKITQKHLK--SSDSHCPVCKDEFE 776
GL+ +I + GG PPA+K ++ LP + T++ LK +++ C +CK+
Sbjct: 183 GLDMIIPDILDDGGPPR----APPASKEVVEKLPVIIFTEELLKKFGAEAECCICKENLV 238
Query: 777 LKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
+ + +++PCKH +H C+ PWL +HN+
Sbjct: 239 IGDKMQELPCKHTFHPPCLKPWLDEHNS 266
>sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo sapiens
GN=RNF181 PE=1 SV=1
Length = 153
Score = 66 bits (160), Expect = 2e-010
Identities = 32/70 (45%), Positives = 45/70 (64%), Gaps = 7/70 (10%)
Frame = +3
Query: 657 HRGPPPAAKSSIDALP--TVKITQKHLKSSDSHCPVCKDEFELKSEAKQMPCKHVYHSDC 830
H PPPAAK+ ++ LP ++ +Q LK CPVC EFE + A +MPC H++HS C
Sbjct: 48 HHLPPPAAKTVVENLPRTVIRGSQAELK-----CPVCLLEFEEEETAIEMPCHHLFHSSC 102
Query: 831 IVPWLVQHNT 860
I+PWL + N+
Sbjct: 103 ILPWLSKTNS 112
>sp|Q9C1X4|YKW3_SCHPO Uncharacterized RING finger protein P32A8.03c
OS=Schizosaccharomyces pombe GN=SPAP32A8.03c PE=2 SV=1
Length = 513
Score = 65 bits (158), Expect = 4e-010
Identities = 34/96 (35%), Positives = 50/96 (52%), Gaps = 5/96 (5%)
Frame = +3
Query: 576 NAGDYFYGP-GLEELIEQLSSSGGTTTHHRGPPPAAKSSIDALPTVKITQKHLKSSDSHC 752
N GDY +G GL+++I QL H P PA + I A V+ K L + C
Sbjct: 341 NPGDYAWGARGLDDIISQLMEQ---AQGHNAPAPAPEDVI-AKMKVQKPPKELIDEEGEC 396
Query: 753 PVCKDEFELKSEAKQMPCKHVYHSDCIVPWLVQHNT 860
+C + F++ + Q+PCKH +H +CI PWL + T
Sbjct: 397 TICMEMFKINDDVIQLPCKHYFHENCIKPWLRVNGT 432
>sp|Q8VEM1|GOLI_MOUSE Goliath homolog OS=Mus musculus GN=Rnf130 PE=2 SV=1
Length = 419
Score = 55 bits (132), Expect = 4e-007
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Frame = +3
Query: 618 IEQLSSSGGTTTHHRGPPPAAKSSIDALP--TVKITQKHLKSSDSHCPVCKDEFELKSEA 791
I+++ + + R AAK +I L TVK K HC VC + ++
Sbjct: 218 IQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVV 277
Query: 792 KQMPCKHVYHSDCIVPWLVQHNT 860
+ +PCKHV+H C+ PWL +H T
Sbjct: 278 RVLPCKHVFHKSCVDPWLSEHCT 300
>sp|Q6Y290|GOLI_RAT Goliath homolog OS=Rattus norvegicus GN=Rnf130 PE=1 SV=1
Length = 419
Score = 55 bits (132), Expect = 4e-007
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Frame = +3
Query: 618 IEQLSSSGGTTTHHRGPPPAAKSSIDALP--TVKITQKHLKSSDSHCPVCKDEFELKSEA 791
I+++ + + R AAK +I L TVK K HC VC + ++
Sbjct: 218 IQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVV 277
Query: 792 KQMPCKHVYHSDCIVPWLVQHNT 860
+ +PCKHV+H C+ PWL +H T
Sbjct: 278 RVLPCKHVFHKSCVDPWLSEHCT 300
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 262,776,655,547
Number of Sequences: 518415
Number of Extensions: 262776655547
Number of Successful Extensions: 1686502940
Number of sequences better than 0.0: 0
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