BLASTX 7.6.2
Query= UN05566 /QuerySize=645
(644 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8R3D1|TBC13_MOUSE TBC1 domain family member 13 OS=Mus muscul... 141 6e-033
sp|Q9NVG8|TBC13_HUMAN TBC1 domain family member 13 OS=Homo sapie... 99 2e-020
sp|Q9URY3|YLOH_SCHPO TBC domain-containing protein C1952.17c OS=... 82 3e-015
sp|Q95KI1|TB22A_MACFA TBC1 domain family member 22A (Fragment) O... 72 3e-012
sp|Q8R5A6|TB22A_MOUSE TBC1 domain family member 22A OS=Mus muscu... 72 3e-012
sp|Q8WUA7|TB22A_HUMAN TBC1 domain family member 22A OS=Homo sapi... 71 6e-012
sp|Q9NU19|TB22B_HUMAN TBC1 domain family member 22B OS=Homo sapi... 71 6e-012
sp|Q95LL3|TB22B_MACFA TBC1 domain family member 22B OS=Macaca fa... 71 6e-012
sp|O59737|GYP1_SCHPO GTPase-activating protein gyp1 OS=Schizosac... 70 1e-011
sp|Q80XQ2|TBCD5_MOUSE TBC1 domain family member 5 OS=Mus musculu... 69 2e-011
sp|Q92609|TBCD5_HUMAN TBC1 domain family member 5 OS=Homo sapien... 68 4e-011
sp|Q54TA5|TBC5B_DICDI TBC1 domain family member 5 homolog B OS=D... 65 4e-010
sp|Q9CXF4|TBC15_MOUSE TBC1 domain family member 15 OS=Mus muscul... 60 1e-008
sp|Q8TC07|TBC15_HUMAN TBC1 domain family member 15 OS=Homo sapie... 57 7e-008
sp|Q08484|GYP1_YEAST GTPase-activating protein GYP1 OS=Saccharom... 55 3e-007
>sp|Q8R3D1|TBC13_MOUSE TBC1 domain family member 13 OS=Mus musculus GN=Tbc1d13
PE=2 SV=1
Length = 400
Score = 141 bits (353), Expect = 6e-033
Identities = 69/158 (43%), Positives = 101/158 (63%), Gaps = 2/158 (1%)
Frame = -3
Query: 639 FRNDPDEDSSSHAEADAFFCFVELLGGFRDFYCQQLDNSVVGIRSAITRLSQLVRKHDEE 460
F DP+ + HAEAD FFCF L+ RD + + LD+S GI + ++ ++ D E
Sbjct: 242 FATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVE 301
Query: 459 LWRHLEITTKVNPQFYAFRWITLLLTQEFSFFDCLHIWDALLSDPEGPLESLLGICCAML 280
L+ L+ + PQF+AFRW+TLLL+QEF D + IWD+L +D + LL +CCAML
Sbjct: 302 LYLKLQ-EQSIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFAD-GNRFDFLLLVCCAML 359
Query: 279 VLVRRRLIAGDFTSNMKLLQHYPTTNISHLLYVANKLR 166
+L+R +L+ GDFT NM+LLQ YP T++ +L A +L+
Sbjct: 360 ILIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQ 397
>sp|Q9NVG8|TBC13_HUMAN TBC1 domain family member 13 OS=Homo sapiens GN=TBC1D13
PE=1 SV=2
Length = 275
Score = 99 bits (245), Expect = 2e-020
Identities = 45/88 (51%), Positives = 65/88 (73%), Gaps = 1/88 (1%)
Frame = -3
Query: 429 VNPQFYAFRWITLLLTQEFSFFDCLHIWDALLSDPEGPLESLLGICCAMLVLVRRRLIAG 250
+ PQF+AFRW+TLLL+QEF D + IWD+L +D + + LL +CCAML+L+R +L+ G
Sbjct: 186 IKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFAD-DNRFDFLLLVCCAMLMLIREQLLEG 244
Query: 249 DFTSNMKLLQHYPTTNISHLLYVANKLR 166
DFT NM+LLQ YP T++ +L A +L+
Sbjct: 245 DFTVNMRLLQDYPITDVCQILQKAKELQ 272
>sp|Q9URY3|YLOH_SCHPO TBC domain-containing protein C1952.17c
OS=Schizosaccharomyces pombe GN=SPAC1952.17c PE=2 SV=4
Length = 619
Score = 82 bits (200), Expect = 3e-015
Identities = 39/106 (36%), Positives = 67/106 (63%), Gaps = 2/106 (1%)
Frame = -3
Query: 642 VFRNDPDEDSSSHAEADAFFCFVELLGGFRDFYCQQLD-NSVVGIRSAITRLSQLVRKHD 466
V DP ++ E DAFF F +++ RD Y + LD +S GI +++ ++ ++K+D
Sbjct: 282 VLATDPTYENYYLCECDAFFLFTQMMVQVRDLYEKTLDHDSDHGIHFLMSKFTERLKKYD 341
Query: 465 EELWRHLEITTKVNPQFYAFRWITLLLTQEFSFFDCLHIWDALLSD 328
ELW +LE +++P +Y+FRW T LL+QEF D + +WD++++D
Sbjct: 342 YELWENLE-EKQIHPTYYSFRWFTCLLSQEFPLPDVIRLWDSIIAD 386
>sp|Q95KI1|TB22A_MACFA TBC1 domain family member 22A (Fragment) OS=Macaca
fascicularis GN=TBC1D22A PE=2 SV=2
Length = 497
Score = 72 bits (175), Expect = 3e-012
Identities = 51/151 (33%), Positives = 79/151 (52%), Gaps = 11/151 (7%)
Frame = -3
Query: 600 EADAFFCFVELLGGFRDFYCQQLDNSVVGIRSAITRLSQLVRKHDEELWRHLEITTKVNP 421
EAD ++C +LL G +D Y + GI+ + L +LV + DE++ RHL+ +V
Sbjct: 340 EADTYWCMSKLLDGIQDNY----TFAQPGIQMKVKMLEELVSRIDEQVHRHLD-QHEVRY 394
Query: 420 QFYAFRWITLLLTQEFSFFDCLHIWDALLSDPEGPLESLLGICCAMLVLVRRRLI-AGDF 244
+AFRW+ LL +E + +WD S+PEG L +C A LV R+ ++ DF
Sbjct: 395 LQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLVRWRKEILEEKDF 454
Query: 243 TSNMKLLQHYPTT-----NISHLLYVANKLR 166
+ LQ+ PT +IS LL A +L+
Sbjct: 455 QELLLFLQNLPTAHWDDEDISLLLAEAYRLK 485
>sp|Q8R5A6|TB22A_MOUSE TBC1 domain family member 22A OS=Mus musculus GN=Tbc1d22a
PE=2 SV=3
Length = 516
Score = 72 bits (175), Expect = 3e-012
Identities = 51/151 (33%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Frame = -3
Query: 600 EADAFFCFVELLGGFRDFYCQQLDNSVVGIRSAITRLSQLVRKHDEELWRHLEITTKVNP 421
EAD ++C +LL G +D Y + GI+ + L +LV + DE + RHL+ +V
Sbjct: 359 EADTYWCMSKLLDGIQDNY----TFAQPGIQMKVKMLEELVSRIDERVHRHLD-GHEVRY 413
Query: 420 QFYAFRWITLLLTQEFSFFDCLHIWDALLSDPEGPLESLLGICCAMLVLVRRRLI-AGDF 244
+AFRW+ LL +E + +WD S+PEG L +C A LV RR ++ DF
Sbjct: 414 LQFAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLVRWRREILEERDF 473
Query: 243 TSNMKLLQHYPTT-----NISHLLYVANKLR 166
+ LQ+ PT ++S LL A +L+
Sbjct: 474 QELLLFLQNLPTARWDDQDVSLLLAEAYRLK 504
>sp|Q8WUA7|TB22A_HUMAN TBC1 domain family member 22A OS=Homo sapiens GN=TBC1D22A
PE=1 SV=2
Length = 517
Score = 71 bits (172), Expect = 6e-012
Identities = 50/151 (33%), Positives = 79/151 (52%), Gaps = 11/151 (7%)
Frame = -3
Query: 600 EADAFFCFVELLGGFRDFYCQQLDNSVVGIRSAITRLSQLVRKHDEELWRHLEITTKVNP 421
EAD ++C +LL G +D Y + GI+ + L +LV + DE++ RHL+ +V
Sbjct: 360 EADTYWCMSKLLDGIQDNY----TFAQPGIQMKVKMLEELVSRIDEQVHRHLD-QHEVRY 414
Query: 420 QFYAFRWITLLLTQEFSFFDCLHIWDALLSDPEGPLESLLGICCAMLVLVRRRLI-AGDF 244
+AFRW+ LL +E + +WD S+P+G L +C A LV R+ ++ DF
Sbjct: 415 LQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDF 474
Query: 243 TSNMKLLQHYPTT-----NISHLLYVANKLR 166
+ LQ+ PT +IS LL A +L+
Sbjct: 475 QELLLFLQNLPTAHWDDEDISLLLAEAYRLK 505
>sp|Q9NU19|TB22B_HUMAN TBC1 domain family member 22B OS=Homo sapiens GN=TBC1D22B
PE=1 SV=3
Length = 505
Score = 71 bits (172), Expect = 6e-012
Identities = 45/139 (32%), Positives = 71/139 (51%), Gaps = 6/139 (4%)
Frame = -3
Query: 621 EDSSSHAEADAFFCFVELLGGFRDFYCQQLDNSVVGIRSAITRLSQLVRKHDEELWRHLE 442
+D EAD+F+C +LL G +D Y + GI+ + L +LV + DE++ H
Sbjct: 341 QDMLRSIEADSFWCMSKLLDGIQDNY----TFAQPGIQKKVKALEELVSRIDEQVHNHFR 396
Query: 441 ITTKVNPQFYAFRWITLLLTQEFSFFDCLHIWDALLSDPEGPLESLLGICCAMLVLVRRR 262
+V +AFRW+ LL +E + +WD S+PEG L +C A L+ R+
Sbjct: 397 -RYEVEYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLIKWRKE 455
Query: 261 LI-AGDFTSNMKLLQHYPT 208
++ DF + LLQ+ PT
Sbjct: 456 ILDEEDFQGLLMLLQNLPT 474
>sp|Q95LL3|TB22B_MACFA TBC1 domain family member 22B OS=Macaca fascicularis
GN=TBC1D22B PE=2 SV=1
Length = 505
Score = 71 bits (172), Expect = 6e-012
Identities = 45/139 (32%), Positives = 71/139 (51%), Gaps = 6/139 (4%)
Frame = -3
Query: 621 EDSSSHAEADAFFCFVELLGGFRDFYCQQLDNSVVGIRSAITRLSQLVRKHDEELWRHLE 442
+D EAD+F+C +LL G +D Y + GI+ + L +LV + DE++ H
Sbjct: 341 QDMLRSIEADSFWCMSKLLDGIQDNY----TFAQPGIQKKVKALEELVSRIDEQVHNHFR 396
Query: 441 ITTKVNPQFYAFRWITLLLTQEFSFFDCLHIWDALLSDPEGPLESLLGICCAMLVLVRRR 262
+V +AFRW+ LL +E + +WD S+PEG L +C A L+ R+
Sbjct: 397 -RYEVEYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLIKWRKE 455
Query: 261 LI-AGDFTSNMKLLQHYPT 208
++ DF + LLQ+ PT
Sbjct: 456 ILDEEDFQGLLMLLQNLPT 474
>sp|O59737|GYP1_SCHPO GTPase-activating protein gyp1 OS=Schizosaccharomyces
pombe GN=gyp1 PE=2 SV=1
Length = 514
Score = 70 bits (169), Expect = 1e-011
Identities = 47/144 (32%), Positives = 75/144 (52%), Gaps = 6/144 (4%)
Frame = -3
Query: 624 DEDSSSHAEADAFFCFVELLGGFRDFYCQQLDNSVVGIRSAITRLSQLVRKHDEELWRHL 445
DE + + EADA++C +LL G +D Y ++ GIR + L +L + DE L +HL
Sbjct: 349 DETNRNDIEADAYWCLSKLLDGIQDNYI----HAQPGIRRQVNNLRELTLRIDEPLVKHL 404
Query: 444 EITTKVNPQFYAFRWITLLLTQEFSFFDCLHIWDALLSD-PEGPLESLLGICCAMLVLVR 268
++ QF +FRW+ LL +E S + + +WD +++ +G E L +C A LV
Sbjct: 405 QMEGVDFLQF-SFRWMNCLLMRELSISNIIRMWDTYMAEGVQGFSEFHLYVCAAFLVKWS 463
Query: 267 RRLIAGDFTSNMKLLQHYPTTNIS 196
L +F + LQ PT + S
Sbjct: 464 SELQKMEFQDILIFLQSIPTKDWS 487
>sp|Q80XQ2|TBCD5_MOUSE TBC1 domain family member 5 OS=Mus musculus GN=Tbc1d5
PE=1 SV=1
Length = 815
Score = 69 bits (168), Expect = 2e-011
Identities = 40/109 (36%), Positives = 62/109 (56%), Gaps = 6/109 (5%)
Frame = -3
Query: 501 ITRLSQ----LVRKHDEELWRHLEITTKVNPQFYAFRWITLLLTQEFSFFDCLHIWDALL 334
+T+++Q L++KHD EL+ HL ++ PQ Y RW+ LL +EF D L +WDAL
Sbjct: 298 VTKVNQIQDHLLKKHDIELYMHLN-RLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALF 356
Query: 333 SDPEGPLESLLGICCAMLVLVRRRLIAGDFTSNMKLLQHYPTTNISHLL 187
+D L + + AML+ +R LI+ ++ + + LL HYP H L
Sbjct: 357 ADSLN-LSLVDYVFTAMLLYIRDALISSNYQTCLGLLMHYPIIGDIHSL 404
>sp|Q92609|TBCD5_HUMAN TBC1 domain family member 5 OS=Homo sapiens GN=TBC1D5
PE=1 SV=1
Length = 795
Score = 68 bits (165), Expect = 4e-011
Identities = 41/109 (37%), Positives = 62/109 (56%), Gaps = 6/109 (5%)
Frame = -3
Query: 501 ITRLSQ----LVRKHDEELWRHLEITTKVNPQFYAFRWITLLLTQEFSFFDCLHIWDALL 334
+T+++Q L++KHD EL+ HL ++ PQ Y RW+ LL +EF D L +WDAL
Sbjct: 298 VTKVNQIQDHLLKKHDIELYMHLN-RLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALF 356
Query: 333 SDPEGPLESLLGICCAMLVLVRRRLIAGDFTSNMKLLQHYPTTNISHLL 187
+D L + I AML+ +R LI+ ++ + + LL HYP H L
Sbjct: 357 ADGLS-LGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSL 404
>sp|Q54TA5|TBC5B_DICDI TBC1 domain family member 5 homolog B OS=Dictyostelium
discoideum GN=tbc1d5B PE=3 SV=1
Length = 1016
Score = 65 bits (156), Expect = 4e-010
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Frame = -3
Query: 489 SQLVRKHDEELWRHLEITTKVNPQFYAFRWITLLLTQEFSFFDCLHIWDALLSDPEGPLE 310
S L+++ D EL++HL+ + + PQ Y RWI LL +EF F D L+IWDAL + E L
Sbjct: 583 SILLKQKDFELYQHLD-SLDIEPQIYLLRWIRLLFGREFHFDDVLNIWDALFAYGEN-LI 640
Query: 309 SLLGICCAMLVLVRRRLIAGDFTSNMKLLQHYPTTNISHLL 187
+ C +ML +R L+ D +K + YP ++L
Sbjct: 641 LIDYFCISMLTYIREHLLKSDSIYALKRIYKYPPVEDVYML 681
>sp|Q9CXF4|TBC15_MOUSE TBC1 domain family member 15 OS=Mus musculus GN=Tbc1d15
PE=1 SV=1
Length = 671
Score = 60 bits (143), Expect = 1e-008
Identities = 37/129 (28%), Positives = 71/129 (55%), Gaps = 9/129 (6%)
Frame = -3
Query: 600 EADAFFCFVELLGGFRDFYCQQLDNSVVGIRSAITRLSQLVRKHDEELWRHLEITTKVNP 421
E DAF+CF + D Q + + G+++ + +LS L+R D +LE +
Sbjct: 453 EVDAFWCF----ASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLE-SQDSGY 507
Query: 420 QFYAFRWITLLLTQEFSFFDCLHIWDALLSDPEGPLESL-LGICCAMLVLVRRRLIAGDF 244
++ FRW+ + +EFSF D L +W+ + + E P ++ L +CCA+L +++++A +
Sbjct: 508 LYFCFRWLLIRFKREFSFLDILRLWEVMWT--ELPCKNFHLLLCCAILESEKQQIMAKHY 565
Query: 243 TSNMKLLQH 217
N ++L+H
Sbjct: 566 GFN-EILKH 573
>sp|Q8TC07|TBC15_HUMAN TBC1 domain family member 15 OS=Homo sapiens GN=TBC1D15
PE=1 SV=2
Length = 691
Score = 57 bits (137), Expect = 7e-008
Identities = 35/128 (27%), Positives = 68/128 (53%), Gaps = 7/128 (5%)
Frame = -3
Query: 600 EADAFFCFVELLGGFRDFYCQQLDNSVVGIRSAITRLSQLVRKHDEELWRHLEITTKVNP 421
E DAF+CF + D Q + + G+++ + +LS L+R D +LE +
Sbjct: 470 EVDAFWCF----ASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLE-SQDSGY 524
Query: 420 QFYAFRWITLLLTQEFSFFDCLHIWDALLSDPEGPLESLLGICCAMLVLVRRRLIAGDFT 241
++ FRW+ + +EFSF D L +W+ + ++ LL +CCA+L +++++ +
Sbjct: 525 LYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCTNFHLL-LCCAILESEKQQIMEKHYG 583
Query: 240 SNMKLLQH 217
N ++L+H
Sbjct: 584 FN-EILKH 590
>sp|Q08484|GYP1_YEAST GTPase-activating protein GYP1 OS=Saccharomyces cerevisiae
GN=GYP1 PE=1 SV=1
Length = 637
Score = 55 bits (132), Expect = 3e-007
Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 5/98 (5%)
Frame = -3
Query: 621 EDSSSHAEADAFFCFVELLGGFRDFYCQQLDNSVVGIRSAITRLSQLVRKHDEELWRHLE 442
++ + EAD F+C +LL D Y + GI + LSQLV++ D +L+ H +
Sbjct: 415 DEQITDLEADTFWCLTKLLEQITDNYI----HGQPGILRQVKNLSQLVKRIDADLYNHFQ 470
Query: 441 ITTKVNPQFYAFRWITLLLTQEFSFFDCLHIWDALLSD 328
V +AFRW+ LL +EF + +WD LS+
Sbjct: 471 -NEHVEFIQFAFRWMNCLLMREFQMGTVIRMWDTYLSE 507
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,113,185,847
Number of Sequences: 518415
Number of Extensions: 22113185847
Number of Successful Extensions: 153311817
Number of sequences better than 0.0: 0
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