BLASTX 7.6.2
Query= UN14417 /QuerySize=1475
(1474 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q58CZ9|ATTY_BOVIN Tyrosine aminotransferase OS=Bos taurus GN=... 267 3e-070
sp|Q8QZR1|ATTY_MOUSE Tyrosine aminotransferase OS=Mus musculus G... 267 3e-070
sp|P04694|ATTY_RAT Tyrosine aminotransferase OS=Rattus norvegicu... 263 3e-069
sp|P17735|ATTY_HUMAN Tyrosine aminotransferase OS=Homo sapiens G... 260 2e-068
sp|Q54K95|ATTY_DICDI Tyrosine aminotransferase OS=Dictyostelium ... 242 7e-063
sp|P33447|ATTY_TRYCR Tyrosine aminotransferase OS=Trypanosoma cr... 220 2e-056
sp|O67781|AAT_AQUAE Aspartate aminotransferase OS=Aquifex aeolic... 138 2e-031
sp|P0A960|YFBQ_ECOL6 Uncharacterized aminotransferase yfbQ OS=Es... 129 8e-029
sp|P0A959|YFBQ_ECOLI Uncharacterized aminotransferase yfbQ OS=Es... 129 8e-029
sp|P0A961|YFBQ_SHIFL Uncharacterized aminotransferase yfbQ OS=Sh... 129 8e-029
sp|Q60317|AAT1_METJA Probable aspartate aminotransferase 1 OS=Me... 111 2e-023
sp|Q9V0L2|AAT_PYRAB Aspartate aminotransferase OS=Pyrococcus aby... 104 2e-021
sp|P52892|ALAT_YEAST Probable alanine aminotransferase OS=Saccha... 99 9e-020
sp|P52893|ALAM_YEAST Probable alanine aminotransferase, mitochon... 95 1e-018
sp|Q8GYY0|1A112_ARATH Probable aminotransferase ACS12 OS=Arabido... 88 2e-016
sp|Q7NDX4|DAPAT_GLOVI LL-diaminopimelate aminotransferase OS=Glo... 82 1e-014
sp|P29535|1A14_SOLLC 1-aminocyclopropane-1-carboxylate synthase ... 80 4e-014
sp|Q30ZX9|DAPAT_DESDG LL-diaminopimelate aminotransferase OS=Des... 78 1e-013
sp|B8DJJ6|DAPAT_DESVM LL-diaminopimelate aminotransferase OS=Des... 78 1e-013
sp|P47039|BNA3_YEAST Probable kynurenine--oxoglutarate transamin... 72 1e-011
>sp|Q58CZ9|ATTY_BOVIN Tyrosine aminotransferase OS=Bos taurus GN=TAT PE=2 SV=1
Length = 447
Score = 267 bits (680), Expect = 3e-070
Identities = 142/428 (33%), Positives = 237/428 (55%), Gaps = 16/428 (3%)
Frame = +3
Query: 54 VSDQKKKMGEIGAK--RWNFGANVVVERSSSLSIREY--LNTLISNL--NEGDTRPVIAF 215
V+ + +G++ ++ RW+ R S +S + + + ++ N+ + +IA
Sbjct: 17 VAGRSSVLGKVKSRKARWSV-------RPSDMSNKTFNPIRAIVDNMKVKPNPNKTMIAL 69
Query: 216 GNGDPSLFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSYQISP 395
GDP++F TDP +A+ DA+ S KFN Y + G +R+ VA Y +
Sbjct: 70 SIGDPTVFGNLPTDPEVTQAMKDALDSGKFNGYVPSIGYLSSREEVASYYHCP-EAPLEA 128
Query: 396 KDVHITSGCLQAVEILISSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLPENGWD 575
KDV +TSGC QA+E+ ++ LA PG NIL+PRP + +Y + A +E++ ++LLPE W+
Sbjct: 129 KDVILTSGCSQAIELCLAVLANPGQNILVPRPGFSLYRTLAESMGIEVKLYNLLPEKNWE 188
Query: 576 VDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAF 755
+DL +E+L D+KTV ++V NP NPCG+VFSR+HLQKI A + + ++ADE+Y F
Sbjct: 189 IDLKQLESLIDEKTVCLIVNNPSNPCGSVFSRRHLQKILAVAARQCVPILADEIYGDMVF 248
Query: 756 GDKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQSLTNVIN 935
D F +A + VP++ G ++KRW VPGWR+GW++ D I + LT +
Sbjct: 249 SDSKFEPLATLSSKVPILSCGGLAKRWLVPGWRMGWILIHDRRDIFGNE-IRDGLTKLSQ 307
Query: 936 ISTDAATFIQGAIPDILGNTKEEFFSLKLERVRECAEICYEEIMKIPCITCPSKPEGSMF 1115
T +QGA+ IL T F+ L ++ A++CY + IP + P P G+M+
Sbjct: 308 RILGPCTLVQGALKSILCRTPRVFYHNTLSFLKSNADLCYGALAAIPGLR-PIHPSGAMY 366
Query: 1116 TMVKLNLSLLGDISDDLDFCCKLAKEESLIILPGRAVGLKNWLRITFAVELDLLIDGFSR 1295
MV + + + +D++F +L E+S+ LP N+ R+ V ++++ SR
Sbjct: 367 LMVGIEMEHFPEFENDVEFTEQLVAEQSVHCLPATCFEYPNFFRVVITVPEVMMLEACSR 426
Query: 1296 LKNFAQRH 1319
++ F ++H
Sbjct: 427 IQEFCEQH 434
>sp|Q8QZR1|ATTY_MOUSE Tyrosine aminotransferase OS=Mus musculus GN=Tat PE=2
SV=1
Length = 454
Score = 267 bits (680), Expect = 3e-070
Identities = 141/412 (34%), Positives = 230/412 (55%), Gaps = 14/412 (3%)
Frame = +3
Query: 96 RWNFGANVVVERSSSLSIREY--LNTLISNL--NEGDTRPVIAFGNGDPSLFPRFSTDPS 263
RWN R S +S + + + ++ N+ + VI+ GDP++F TDP
Sbjct: 40 RWNV-------RPSDMSNKTFNPIRAIVDNMKVKPNPNKTVISLSIGDPTVFGNLPTDPE 92
Query: 264 AVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSYQISPKDVHITSGCLQAVEIL 443
+A+ DA+ S K+N YA + G +R+ VA Y + KDV +TSGC QA+E+
Sbjct: 93 VTQAMKDALDSGKYNGYAPSIGYLSSREEVASYYHCP-EAPLEAKDVILTSGCSQAIELC 151
Query: 444 ISSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLPENGWDVDLDAVEALADDKTVA 623
++ LA PG NIL+PRP + +Y + A +E++ ++LLPE W++DL +E+L D+KT
Sbjct: 152 LAVLANPGQNILIPRPGFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDEKTAC 211
Query: 624 IVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDKPFVSMAEFAEIVP 803
+VV NP NPCG+VFS++HLQKI A + + ++ADE+Y F D + MA + VP
Sbjct: 212 LVVNNPSNPCGSVFSKRHLQKILAVAERQCVPILADEIYGDMVFSDCKYEPMATLSTNVP 271
Query: 804 VVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQSLTNVINISTDAATFIQGAIPDI 983
++ G ++KRW VPGWRLGW++ D I + L + T +QGA+ I
Sbjct: 272 ILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNE-IRDGLVKLSQRILGPCTIVQGALKSI 330
Query: 984 LGNTKEEFFSLKLERVRECAEICYEEIMKIPCITCPSKPEGSMFTMVKLNLSLLGDISDD 1163
L T +EF+ L ++ A++CY + IP + P +P G+M+ MV + + + +D
Sbjct: 331 LQRTPQEFYQDTLSFLKSNADLCYGALSAIPGLQ-PVRPSGAMYLMVGIEMEHFPEFEND 389
Query: 1164 LDFCCKLAKEESLIILPGRAVGLKNWLRITFAVELDLLIDGFSRLKNFAQRH 1319
++F +L E+S+ LP N+ R+ V ++++ SR++ F ++H
Sbjct: 390 VEFTERLIAEQSVHCLPATCFEYPNFFRVVITVPEVMMLEACSRIQEFCEQH 441
>sp|P04694|ATTY_RAT Tyrosine aminotransferase OS=Rattus norvegicus GN=Tat PE=1
SV=1
Length = 454
Score = 263 bits (671), Expect = 3e-069
Identities = 136/401 (33%), Positives = 227/401 (56%), Gaps = 7/401 (1%)
Frame = +3
Query: 129 RSSSLSIREY--LNTLISNL--NEGDTRPVIAFGNGDPSLFPRFSTDPSAVKAICDAVSS 296
R S +S + + + ++ N+ + VI+ GDP++F TDP +A+ DA+ S
Sbjct: 44 RPSDMSNKTFNPIRAIVDNMKVQPNPNKTVISLSIGDPTVFGNLPTDPEVTQAMKDALDS 103
Query: 297 NKFNNYASASGIPVARKAVAEYLSRDLSYQISPKDVHITSGCLQAVEILISSLAKPGANI 476
K+N YA + G +R+ VA Y + KDV +TSGC QA+E+ ++ LA PG NI
Sbjct: 104 GKYNGYAPSIGYLSSREEVASYYHCH-EAPLEAKDVILTSGCSQAIELCLAVLANPGQNI 162
Query: 477 LLPRPTYPMYDSRASFSQLEIRYFDLLPENGWDVDLDAVEALADDKTVAIVVVNPCNPCG 656
L+PRP + +Y + A +E++ ++LLPE W++DL +E+L D+KT +VV NP NPCG
Sbjct: 163 LIPRPGFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDEKTACLVVNNPSNPCG 222
Query: 657 NVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDKPFVSMAEFAEIVPVVLLGAISKRW 836
+VFS++HLQKI A + + ++ADE+Y F D + +A + VP++ G ++KRW
Sbjct: 223 SVFSKRHLQKILAVAERQCVPILADEIYGDMVFSDCKYEPLANLSTNVPILSCGGLAKRW 282
Query: 837 FVPGWRLGWMVTLDPHSIMKDSGFLQSLTNVINISTDAATFIQGAIPDILGNTKEEFFSL 1016
VPGWRLGW++ D I + L + T +QGA+ IL T +EF+
Sbjct: 283 LVPGWRLGWILIHDRRDIFGNE-IRDGLVKLSQRILGPCTIVQGALKSILQRTPQEFYHD 341
Query: 1017 KLERVRECAEICYEEIMKIPCITCPSKPEGSMFTMVKLNLSLLGDISDDLDFCCKLAKEE 1196
L ++ A++CY + IP + P +P G+M+ MV + + + +D++F +L E+
Sbjct: 342 TLSFLKSNADLCYGALAAIPGLQ-PVRPSGAMYLMVGIEMEHFPEFENDVEFTERLIAEQ 400
Query: 1197 SLIILPGRAVGLKNWLRITFAVELDLLIDGFSRLKNFAQRH 1319
++ LP N+ R+ V ++++ SR++ F ++H
Sbjct: 401 AVHCLPATCFEYPNFFRVVITVPEVMMLEACSRIQEFCEQH 441
>sp|P17735|ATTY_HUMAN Tyrosine aminotransferase OS=Homo sapiens GN=TAT PE=1
SV=1
Length = 454
Score = 260 bits (664), Expect = 2e-068
Identities = 129/374 (34%), Positives = 215/374 (57%), Gaps = 3/374 (0%)
Frame = +3
Query: 198 RPVIAFGNGDPSLFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDL 377
+ +I+ GDP++F TDP +A+ DA+ S K+N YA + G +R+ +A Y
Sbjct: 71 KTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSREEIASYYHCP- 129
Query: 378 SYQISPKDVHITSGCLQAVEILISSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLL 557
+ KDV +TSGC QA+++ ++ LA PG NIL+PRP + +Y + A +E++ ++LL
Sbjct: 130 EAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLL 189
Query: 558 PENGWDVDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEV 737
PE W++DL +E L D+KT ++V NP NPCG+VFS++HLQKI A + + ++ADE+
Sbjct: 190 PEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEI 249
Query: 738 YDHYAFGDKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQS 917
Y F D + +A + VP++ G ++KRW VPGWRLGW++ D I +
Sbjct: 250 YGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNE-IRDG 308
Query: 918 LTNVINISTDAATFIQGAIPDILGNTKEEFFSLKLERVRECAEICYEEIMKIPCITCPSK 1097
L + T +QGA+ IL T EF+ L ++ A++CY + IP + P +
Sbjct: 309 LVKLSQRILGPCTIVQGALKSILCRTPGEFYHNTLSFLKSNADLCYGALAAIPGLR-PVR 367
Query: 1098 PEGSMFTMVKLNLSLLGDISDDLDFCCKLAKEESLIILPGRAVGLKNWLRITFAVELDLL 1277
P G+M+ MV + + + +D++F +L E+S+ LP N++R+ V ++
Sbjct: 368 PSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCFEYPNFIRVVITVPEVMM 427
Query: 1278 IDGFSRLKNFAQRH 1319
++ SR++ F ++H
Sbjct: 428 LEACSRIQEFCEQH 441
>sp|Q54K95|ATTY_DICDI Tyrosine aminotransferase OS=Dictyostelium discoideum
GN=tat PE=3 SV=1
Length = 417
Score = 242 bits (616), Expect = 7e-063
Identities = 133/423 (31%), Positives = 235/423 (55%), Gaps = 18/423 (4%)
Frame = +3
Query: 84 IGAKRWNFGANVVVERSSSLSIREYLNTLISNLNEGDTRP-----VIAFGNGDPSLFPRF 248
+ ++WN SS S N + +++G +P I+ GDP +F
Sbjct: 5 VSQRKWNV--------ESSKSANNAFNPIRRIVDKGGFKPNPNKSTISLSIGDPCVFGNL 56
Query: 249 STDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSYQISPKDVHITSGCLQ 428
+ A + + + S+KFN Y ++G +AR+AVA+Y+ S +++ KD+ + SG
Sbjct: 57 NILDYANDLLIENIKSSKFNGYPPSTGYEIAREAVAKYVETPTS-KLTSKDIIVASGASG 115
Query: 429 AVEILISSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLPENGWDVDLDAVEALAD 608
A+E+ I L G NIL+P+P +P+Y+ + + +++++LL + G++VDL+ + +L D
Sbjct: 116 AIELAIGVLLNEGDNILVPKPGFPLYECTSKTKFINVKHYNLLEKQGFNVDLEHLRSLID 175
Query: 609 DKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDKPFVSMAEF 788
DKT AI+V NP NPCG V+S+QHL I + A + + +IADE+Y FG+ F MA
Sbjct: 176 DKTKAILVNNPSNPCGIVYSKQHLLDIIQVAREYCLPIIADEIYSDLTFGEHKFYPMASL 235
Query: 789 AEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQSLTNVINISTDAATFIQG 968
+ VP++ +G I+KR+ VPGWRLGW+ D +I + ++ L ++ + + +Q
Sbjct: 236 TDKVPILSIGGIAKRFLVPGWRLGWVAIHDRDNIFSNGRIIEGLISLSQVILGPNSLVQS 295
Query: 969 AIPDILG--NTK-EEFFSLKLERVRECAEICYEEIMKIPCITCPSKPEGSMFTMVKLNLS 1139
+P +L NT+ +E+ S + + +++ + + K + P G+M+ M++++ S
Sbjct: 296 ILPKLLDPQNTQVKEWCSTITKTLESHSKLTVDMLSKANGLK-PVCSSGTMYQMIEIDCS 354
Query: 1140 LLGDISDDLDFCCKLAKEESLIILPGRAVGLKNWLRITFAVELDLLIDGFSRLKNFAQRH 1319
DI+DD +F KL +E+S+ +L G L N+ RI F +D L + + R+ F + H
Sbjct: 355 KYEDIADDNEFVGKLLEEQSVFLLQGTVFSLPNFFRIVFCAPIDKLTEAYERIIEFCETH 414
Query: 1320 SKK 1328
KK
Sbjct: 415 KKK 417
>sp|P33447|ATTY_TRYCR Tyrosine aminotransferase OS=Trypanosoma cruzi PE=1 SV=2
Length = 416
Score = 220 bits (560), Expect = 2e-056
Identities = 126/386 (32%), Positives = 204/386 (52%), Gaps = 15/386 (3%)
Frame = +3
Query: 198 RPVIAFGNGDPSLFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYL---- 365
+P+I GDP+L T + +K + +A+ S + N Y G P AR+AVA +
Sbjct: 33 KPIIKLSVGDPTLDKNLLTSAAQIKKLKEAIDSQECNGYFPTVGSPEAREAVATWWRNSF 92
Query: 366 --SRDLSYQISPKDVHITSGCLQAVEILISSLAKPGANILLPRPTYPMYDSRASFSQLEI 539
+L I +V + SG + + I+++ G L+P+P +P Y++ + +
Sbjct: 93 VHKEELKSTIVKDNVVLCSGGSHGILMAITAICDAGDYALVPQPGFPHYETVCKAYGIGM 152
Query: 540 RYFDLLPENGWDVDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGIL 719
+++ PEN W+ DLD + L DDKT ++V NP NPCG+ FSR+H++ I A +L +
Sbjct: 153 HFYNCRPENDWEADLDEIRRLKDDKTKLLIVTNPSNPCGSNFSRKHVEDIVRLAEELRLP 212
Query: 720 LIADEVYDHYAFGDK----PFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHS 887
L +DE+Y F K F S+A+F VP V+LG +K VPGWRLGW++ +DPH
Sbjct: 213 LFSDEIYAGMVFKGKDPNATFTSVADFETTVPRVILGGTAKNLVVPGWRLGWLLYVDPHG 272
Query: 888 IMKDSGFLQSLTNVINISTDAATFIQGAIPDILGNTKEEFFSLKLERVRECAEICYEEIM 1067
FL+ L V + T +Q A+ + L NT +E + ++ E A Y I
Sbjct: 273 --NGPSFLEGLKRVGMLVCGPCTVVQAALGEALLNTPQEHLDQIVAKIEESAMYLYNHIG 330
Query: 1068 KIPCI-TCPSKPEGSMFTMVKLNLSLLGDISDDLDFCCKLAKEESLIILPGRAVGLKNWL 1244
+ CI P+ P G+M+ M +++L DI D++F KL +EE++ +LPG +
Sbjct: 331 E--CIGLAPTMPRGAMYLMSRIDLEKYRDIKTDVEFFEKLLEEENVQVLPGTIFHAPGFT 388
Query: 1245 RITFAVELDLLIDGFSRLKNFAQRHS 1322
R+T +++ + R+K F QRH+
Sbjct: 389 RLTTTRPVEVYREAVERIKAFCQRHA 414
>sp|O67781|AAT_AQUAE Aspartate aminotransferase OS=Aquifex aeolicus GN=aspC PE=3
SV=1
Length = 394
Score = 138 bits (345), Expect = 2e-031
Identities = 97/317 (30%), Positives = 163/317 (51%), Gaps = 36/317 (11%)
Frame = +3
Query: 204 VIAFGNGDPSLFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSY 383
VI FG G+P F T P +K C YA ++GIP R+A+AE L ++
Sbjct: 34 VIGFGAGEPD----FDT-PDFIKEACIRALREGKTKYAPSAGIPELREAIAEKLLKENKV 88
Query: 384 QISPKDVHITSGCLQAVEILISSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLP- 560
+ P ++ +++G + ++ ++ G +LLP P + Y +IR+F +P
Sbjct: 89 EYKPSEIVVSAGAKMVLFLIFMAILDEGDEVLLPSPYWVTYPE-------QIRFFGGVPV 141
Query: 561 ------ENGWDVDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILL 722
E G+ + L+ V+ ++T AIV+ +P NP G V+ + L+KIAE + GI +
Sbjct: 142 EVPLKKEKGFQLSLEDVKEKVTERTKAIVINSPNNPTGAVYEEEELKKIAEFCVERGIFI 201
Query: 723 IADEVYDHYAFGDKPFVSMAEFAEIVPVV--LLGAISKRWFVPGWRLGWMVTLDPHSIMK 896
I+DE Y+++ +GD FVS A F++ V + + A SK + + GWR+G++ + ++ +
Sbjct: 202 ISDECYEYFVYGDAKFVSPASFSDEVKNITFTVNAFSKSYSMTGWRIGYVACPEEYAKVI 261
Query: 897 DSGFLQSLTNVINISTDAATFIQGAIPDILGNTKEEFFSLKL----ERVRECAEICYEEI 1064
S QS++NV TF Q + L N K + F ++ ER R+ A EE+
Sbjct: 262 ASLNSQSVSNV-------TTFAQYGALEALKNPKSKDFVNEMRNAFERRRDTA---VEEL 311
Query: 1065 MKIPCITCPSKPEGSMF 1115
KIP + KPEG+ +
Sbjct: 312 SKIPGMDV-VKPEGAFY 327
>sp|P0A960|YFBQ_ECOL6 Uncharacterized aminotransferase yfbQ OS=Escherichia coli
O6 GN=yfbQ PE=3 SV=1
Length = 405
Score = 129 bits (322), Expect = 8e-029
Identities = 93/353 (26%), Positives = 167/353 (47%), Gaps = 11/353 (3%)
Frame = +3
Query: 186 EGDTRPVIAFGNGDPSLFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYL 365
E + V+ G+P+ F + D V I + ++ Y + G+ ARKA+ ++
Sbjct: 29 EEEGNKVLKLNIGNPAPFGFDAPDEILVDVIRNLPTA---QGYCDSKGLYSARKAIMQHY 85
Query: 366 SRDLSYQISPKDVHITSGCLQAVEILISSLAKPGANILLPRPTYPMYDSRASFSQLEIRY 545
++ +D++I +G + + + +L G +L+P P YP++ + S S + +
Sbjct: 86 QARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVH 145
Query: 546 FDLLPENGWDVDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLI 725
+ + W DLD + A +T IV++NP NP G V+S++ L +I E A + +++
Sbjct: 146 YLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIF 205
Query: 726 ADEVYDHYAFGDKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSG 905
ADE+YD + D S+A A + + +SK + V G+R GWMV P K G
Sbjct: 206 ADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAK--G 263
Query: 906 FLQSLTNVINISTDAATFIQGAIPDILGNTKE-EFFSLKLERVRECAEICYEEIMKIPCI 1082
+++ L + ++ A Q AI LG + F R+ E +E I IP +
Sbjct: 264 YIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGV 323
Query: 1083 TCPSKPEGSMFTMVKLNLSLLGDISDDLDFCCKLAKEESLIILPGRAVGLKNW 1241
+C KP G+++ K++ +I DD +E ++++ G A NW
Sbjct: 324 SC-VKPRGALYMFPKIDAKRF-NIHDDQKMVLDFLLQEKVLLVQGTAF---NW 371
>sp|P0A959|YFBQ_ECOLI Uncharacterized aminotransferase yfbQ OS=Escherichia coli
(strain K12) GN=yfbQ PE=1 SV=1
Length = 405
Score = 129 bits (322), Expect = 8e-029
Identities = 93/353 (26%), Positives = 167/353 (47%), Gaps = 11/353 (3%)
Frame = +3
Query: 186 EGDTRPVIAFGNGDPSLFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYL 365
E + V+ G+P+ F + D V I + ++ Y + G+ ARKA+ ++
Sbjct: 29 EEEGNKVLKLNIGNPAPFGFDAPDEILVDVIRNLPTA---QGYCDSKGLYSARKAIMQHY 85
Query: 366 SRDLSYQISPKDVHITSGCLQAVEILISSLAKPGANILLPRPTYPMYDSRASFSQLEIRY 545
++ +D++I +G + + + +L G +L+P P YP++ + S S + +
Sbjct: 86 QARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVH 145
Query: 546 FDLLPENGWDVDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLI 725
+ + W DLD + A +T IV++NP NP G V+S++ L +I E A + +++
Sbjct: 146 YLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIF 205
Query: 726 ADEVYDHYAFGDKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSG 905
ADE+YD + D S+A A + + +SK + V G+R GWMV P K G
Sbjct: 206 ADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAK--G 263
Query: 906 FLQSLTNVINISTDAATFIQGAIPDILGNTKE-EFFSLKLERVRECAEICYEEIMKIPCI 1082
+++ L + ++ A Q AI LG + F R+ E +E I IP +
Sbjct: 264 YIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGV 323
Query: 1083 TCPSKPEGSMFTMVKLNLSLLGDISDDLDFCCKLAKEESLIILPGRAVGLKNW 1241
+C KP G+++ K++ +I DD +E ++++ G A NW
Sbjct: 324 SC-VKPRGALYMFPKIDAKRF-NIHDDQKMVLDFLLQEKVLLVQGTAF---NW 371
>sp|P0A961|YFBQ_SHIFL Uncharacterized aminotransferase yfbQ OS=Shigella flexneri
GN=yfbQ PE=3 SV=1
Length = 405
Score = 129 bits (322), Expect = 8e-029
Identities = 93/353 (26%), Positives = 167/353 (47%), Gaps = 11/353 (3%)
Frame = +3
Query: 186 EGDTRPVIAFGNGDPSLFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYL 365
E + V+ G+P+ F + D V I + ++ Y + G+ ARKA+ ++
Sbjct: 29 EEEGNKVLKLNIGNPAPFGFDAPDEILVDVIRNLPTA---QGYCDSKGLYSARKAIMQHY 85
Query: 366 SRDLSYQISPKDVHITSGCLQAVEILISSLAKPGANILLPRPTYPMYDSRASFSQLEIRY 545
++ +D++I +G + + + +L G +L+P P YP++ + S S + +
Sbjct: 86 QARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVH 145
Query: 546 FDLLPENGWDVDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLI 725
+ + W DLD + A +T IV++NP NP G V+S++ L +I E A + +++
Sbjct: 146 YLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIF 205
Query: 726 ADEVYDHYAFGDKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSG 905
ADE+YD + D S+A A + + +SK + V G+R GWMV P K G
Sbjct: 206 ADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAK--G 263
Query: 906 FLQSLTNVINISTDAATFIQGAIPDILGNTKE-EFFSLKLERVRECAEICYEEIMKIPCI 1082
+++ L + ++ A Q AI LG + F R+ E +E I IP +
Sbjct: 264 YIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGV 323
Query: 1083 TCPSKPEGSMFTMVKLNLSLLGDISDDLDFCCKLAKEESLIILPGRAVGLKNW 1241
+C KP G+++ K++ +I DD +E ++++ G A NW
Sbjct: 324 SC-VKPRGALYMFPKIDAKRF-NIHDDQKMVLDFLLQEKVLLVQGTAF---NW 371
>sp|Q60317|AAT1_METJA Probable aspartate aminotransferase 1
OS=Methanocaldococcus jannaschii GN=MJ0001 PE=3 SV=1
Length = 375
Score = 111 bits (276), Expect = 2e-023
Identities = 73/270 (27%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = +3
Query: 195 TRPVIAFGNGDPSLFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRD 374
T I G G+P F T ++A A+ K +Y+ +GIP R+ ++ L D
Sbjct: 22 TSDCINLGIGEPD----FDTPKHIIEAAKRALDEGK-THYSPNNGIPELREEISNKLKDD 76
Query: 375 LSYQISPKDVHITSGCLQAVEILISSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDL 554
+ + ++ +T G +A+ + I +L G +L+P P++ Y S F++ +I+ DL
Sbjct: 77 YNLDVDKDNIIVTCGASEALMLSIMTLIDRGDEVLIPNPSFVSYFSLTEFAEGKIKNIDL 136
Query: 555 LPENGWDVDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADE 734
+ +++DL+ V+ KT I+ +P NP G V+ ++ ++ +AE A +++++DE
Sbjct: 137 --DENFNIDLEKVKESITKKTKLIIFNSPSNPTGKVYDKETIKGLAEIAEDYNLIIVSDE 194
Query: 735 VYDHYAFGDKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQ 914
VYD + DK S +F + +L+ SK + + GWR+G++ D + K+ +
Sbjct: 195 VYDKIIY-DKKHYSPMQFTD--RCILINGFSKTYAMTGWRIGYLAVSD--ELNKELDLIN 249
Query: 915 SLTNVINIS-TDAATFIQ-GAIPDILGNTK 998
++ + S A TF Q GA+ + G+ K
Sbjct: 250 NMIKIHQYSFACATTFAQYGALAALRGSQK 279
>sp|Q9V0L2|AAT_PYRAB Aspartate aminotransferase OS=Pyrococcus abyssi GN=aspC
PE=3 SV=1
Length = 389
Score = 104 bits (258), Expect = 2e-021
Identities = 63/228 (27%), Positives = 120/228 (52%), Gaps = 13/228 (5%)
Frame = +3
Query: 198 RPVIAFGNGDPSLFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDL 377
+ VI+ G G+P F T P +K +Y G+P R+A+AE L +
Sbjct: 26 KDVISLGIGEPD----FDT-PQHIKEYAKEALDMGLTHYGPNIGLPELREAIAEKLKKQN 80
Query: 378 SYQISP-KDVHITSGCLQAVEILISSLAKPGANILLPRPTYPMYDSR---ASFSQLEIRY 545
+ + P K++ + G QA + +S+ K G +L+P P + Y A +E+
Sbjct: 81 NIEADPNKEIMVLVGANQAFLMGLSAFLKDGEEVLIPTPAFVSYAPAVILAGGKPVEVPT 140
Query: 546 FDLLPENGWDVDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLI 725
++ EN + +++D ++ +KT A+++ +PCNP G+V ++ L++IA+ A + +++I
Sbjct: 141 YE---ENEFRLNVDELKKYVTEKTKALIINSPCNPTGSVLKKKDLEEIADFAVEHDLIVI 197
Query: 726 ADEVYDHYAFGDKPFVSMAEFAEIVP-VVLLGAISKRWFVPGWRLGWM 866
+DEVY+H+ + D S+A + + + SK + + GWRLG++
Sbjct: 198 SDEVYEHFIYDDVKHYSIASLDGMFERTITVNGFSKTFAMTGWRLGFV 245
>sp|P52892|ALAT_YEAST Probable alanine aminotransferase OS=Saccharomyces
cerevisiae GN=ALT2 PE=1 SV=1
Length = 507
Score = 99 bits (244), Expect = 9e-020
Identities = 54/164 (32%), Positives = 89/164 (54%), Gaps = 8/164 (4%)
Frame = +3
Query: 312 YASASGIPVARKAVAEYLS-RDLSYQISPKDVHITSGCLQAVEILISSLAKPG-ANILLP 485
Y+ + G+P R+ VA++++ RD +P+D+++T+G A L+S L K +L+P
Sbjct: 136 YSHSQGVPGIRQTVADFITRRDGGEPATPEDIYLTTGASSAATSLLSLLCKDSQTGLLIP 195
Query: 486 RPTYPMYDSRASFSQLEIRYFDLLPENGWDVDLDAVEALADD------KTVAIVVVNPCN 647
P YP+Y + AS ++ + L E+ W + D +E + D + ++V+NP N
Sbjct: 196 IPQYPLYTASASLFNAQVLPYYLDEESNWSTNSDEIEKVVQDALKKQIRPSVLIVINPGN 255
Query: 648 PCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDKPFVSM 779
P G V S + + +I A K GI +I+DEVY F D F SM
Sbjct: 256 PTGAVLSEETIARICLIAAKYGITIISDEVYQENIFNDVKFHSM 299
>sp|P52893|ALAM_YEAST Probable alanine aminotransferase, mitochondrial
OS=Saccharomyces cerevisiae GN=ALT1 PE=1 SV=1
Length = 592
Score = 95 bits (234), Expect = 1e-018
Identities = 54/164 (32%), Positives = 90/164 (54%), Gaps = 8/164 (4%)
Frame = +3
Query: 312 YASASGIPVARKAVAEYLSRDLSYQIS-PKDVHITSGCLQAVEILISSLAK-PGANILLP 485
Y+S+ G+ RK+VAE++++ +IS P+D+ +T+G AV L+S + P +L+P
Sbjct: 221 YSSSQGVEGIRKSVAEFITKRDEGEISYPEDIFLTAGASAAVNYLLSIFCRGPETGVLIP 280
Query: 486 RPTYPMYDSRASFSQLEIRYFDLLPENGWDVDLDAVEALADD------KTVAIVVVNPCN 647
P YP+Y + + + + + L +GW + + +E + + K +VV+NP N
Sbjct: 281 IPQYPLYTATLALNNSQALPYYLDENSGWSTNPEEIETVVKEAIQNEIKPTVLVVINPGN 340
Query: 648 PCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDKPFVSM 779
P G V S + + +I E A K G ++IADEVY F F SM
Sbjct: 341 PTGAVLSPESIAQIFEVAAKYGTVVIADEVYQENIFPGTKFHSM 384
>sp|Q8GYY0|1A112_ARATH Probable aminotransferase ACS12 OS=Arabidopsis thaliana
GN=ACS12 PE=2 SV=2
Length = 495
Score = 88 bits (216), Expect = 2e-016
Identities = 63/197 (31%), Positives = 99/197 (50%), Gaps = 14/197 (7%)
Frame = +3
Query: 312 YASASGIPVARKAVAEYLSRDLSYQIS--PKDVHITSGCLQAVEILISSLAKPGANILLP 485
Y G+ R A A+++SR + +S P ++ IT+G A+E+L LA G L+P
Sbjct: 148 YKPFEGLLELRVAFADFMSRIMGGNVSFDPSNMVITAGGTPAIEVLAFCLADHGNAFLIP 207
Query: 486 RPTYPMYDSRASF-SQLEIRYFDLLPENGWDVDLDAVEALAD------DKTVAIVVVNPC 644
P YP +D F + +E+ + + V + A+E + K I+ NP
Sbjct: 208 TPYYPGFDRDIKFRTGVELIPVHCRSSDNFTVTVSALEQALNQARKRGSKVSGILFSNPS 267
Query: 645 NPCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDKPFVSMAEFA-----EIVPVV 809
NP GN+ SR+ L I A + I +I+DE++ +GDK FVSMAE A + V
Sbjct: 268 NPVGNILSRETLCDILRFAQEKNIHVISDEIFAGSVYGDKEFVSMAEIAGSGEFDKTRVH 327
Query: 810 LLGAISKRWFVPGWRLG 860
++ +SK +PG+R G
Sbjct: 328 IIYGLSKDLSIPGFRAG 344
>sp|Q7NDX4|DAPAT_GLOVI LL-diaminopimelate aminotransferase OS=Gloeobacter
violaceus GN=dapL PE=1 SV=1
Length = 392
Score = 82 bits (200), Expect = 1e-014
Identities = 64/226 (28%), Positives = 97/226 (42%), Gaps = 9/226 (3%)
Frame = +3
Query: 204 VIAFGNGDPSLFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSY 383
+I G GDP T P ++A+ A+ +NY G R+A A + R
Sbjct: 32 IINMGIGDPDK----PTPPVVLEAMHAAIDDPSTHNYPPYKGTKAYREAAAAWFERRFGV 87
Query: 384 QISPKDVHITS--GCLQAVEILISSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLL 557
D + S G +A+ + PG L+P P YP+Y + F+ E LL
Sbjct: 88 GGFHPDTEVISSIGSKEAIHNTFLAFVDPGDYTLIPDPAYPVYRTSTIFAGGEFFAMPLL 147
Query: 558 PENGWDVDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEV 737
PEN DL+AV K + + P NP G V S + +K+ A K IL+ D
Sbjct: 148 PENQLLPDLEAVPETVARKAKLLWLNYPNNPTGAVASLEFFEKVVHFAKKHDILVCHDNA 207
Query: 738 YDHYAFG--DKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMV 869
Y A+ P + A V + L + SK + + GWR+G+++
Sbjct: 208 YSEMAYDGYKPPSILQVPGARDVAIEFL-SCSKAYNMTGWRVGFVI 252
>sp|P29535|1A14_SOLLC 1-aminocyclopropane-1-carboxylate synthase 4 OS=Solanum
lycopersicum GN=ACS4 PE=2 SV=1
Length = 476
Score = 80 bits (195), Expect = 4e-014
Identities = 61/220 (27%), Positives = 103/220 (46%), Gaps = 20/220 (9%)
Frame = +3
Query: 255 DPSAVKAICDAVSS-NKFNNYASASGIPVARKAVAEYL--SRDLSYQISPKDVHITSGCL 425
+P A D + S + N+ G+P A+A+++ +R + K V + G
Sbjct: 75 NPKASICTNDGIESFRRIANFQDYHGLPEFTNAIAKFMEKTRGGKVKFDAKRVVMAGGAT 134
Query: 426 QAVEILISSLAKPGANILLPRPTYPMYDSRASF-SQLEIRYFDLLPENGWDVDLDAVEAL 602
A E LI LA PG L+P P YP ++ + S +++ N + + ++A+E
Sbjct: 135 GANETLILCLADPGDAFLVPTPYYPGFNRDLRWRSGVQLLPISCKSCNNFKITIEAIEEA 194
Query: 603 ------ADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDK 764
A+ K +++ NPCNP G + R L+KI+ + I L+ DE+Y F
Sbjct: 195 YEKGQQANVKIKGLILTNPCNPLGTILDRDTLKKISTFTNEHNIHLVCDEIYAATVFNSP 254
Query: 765 PFVSMAEF--------AEIVPVVLLGAISKRWFVPGWRLG 860
FVS+AE ++V +V ++SK PG+R+G
Sbjct: 255 KFVSIAEIINEDNCINKDLVHIV--SSLSKDLGFPGFRVG 292
>sp|Q30ZX9|DAPAT_DESDG LL-diaminopimelate aminotransferase OS=Desulfovibrio
desulfuricans (strain G20) GN=dapL PE=3 SV=1
Length = 388
Score = 78 bits (191), Expect = 1e-013
Identities = 57/225 (25%), Positives = 102/225 (45%), Gaps = 7/225 (3%)
Frame = +3
Query: 204 VIAFGNGDPSLFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSY 383
+I+ G GDP + T ++A+ A + Y S +G+ R+ VA + R +
Sbjct: 35 IISLGIGDPDM----PTPDFVIEALKKAAEKPANHQYPSYTGMLAFRQEVANWYKRRYAV 90
Query: 384 QISPK-DVHITSGCLQAVEILISSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLP 560
++ PK +V G + + ++ PG +L+ P YP+Y + F ++ LL
Sbjct: 91 ELDPKTEVLTLIGSKEGIAHFPTAFVNPGDLVLVCPPCYPVYAIASRFMGGVVQELPLLE 150
Query: 561 ENGWDVDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVY 740
EN + DLDAV+ +K I V P NP + R +K+ A K ++++ D Y
Sbjct: 151 ENDFLPDLDAVDEATWEKARCIFVNYPNNPTAAMAPRSFFEKLIGIARKHNVIVVHDAAY 210
Query: 741 D--HYAFGDKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMV 869
+Y ++P M + + ++SK + + GWR+ V
Sbjct: 211 TEMYYNENNRPLSIMEIPGAMDVAIEFNSLSKPYNMTGWRIAMAV 255
>sp|B8DJJ6|DAPAT_DESVM LL-diaminopimelate aminotransferase OS=Desulfovibrio
vulgaris (strain Miyazaki F / DSM 19637) GN=dapL PE=3 SV=1
Length = 389
Score = 78 bits (191), Expect = 1e-013
Identities = 62/226 (27%), Positives = 101/226 (44%), Gaps = 9/226 (3%)
Frame = +3
Query: 204 VIAFGNGDPSLFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSY 383
+I+ G GDP + T ++A+ AV + Y S G+ R+ VA + R
Sbjct: 35 IISLGIGDPDM----PTPDFIIEAMKKAVERPANHQYPSYVGMLEFRQEVANWYGRRFGV 90
Query: 384 QISPK-DVHITSGCLQAVEILISSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLP 560
+ PK +V G + + + PG +L+ P YP+Y F E+++ L+
Sbjct: 91 SLDPKTEVIGLIGSKEGIAHFPLAFVNPGDLVLVCTPNYPVYHIATGFVGGEVQFIPLVE 150
Query: 561 ENGWDVDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVY 740
EN + DLDA+ A D+ I V P NP R +K+ K +++ D Y
Sbjct: 151 ENDYLPDLDAIPAATWDRAKMIFVNYPNNPTAATAPRAFYEKLIGICRKHNVIIAHDTAY 210
Query: 741 D--HYAFGDKPFVSMAEFAEIVPVVL-LGAISKRWFVPGWRLGWMV 869
+Y DKP +S+ E V + ++SK + + GWR+G V
Sbjct: 211 TEVYYDENDKP-MSILEVEGAKDVTIEFHSLSKTYNMTGWRVGMAV 255
>sp|P47039|BNA3_YEAST Probable kynurenine--oxoglutarate transaminase BNA3
OS=Saccharomyces cerevisiae GN=BNA3 PE=1 SV=1
Length = 444
Score = 72 bits (174), Expect = 1e-011
Identities = 36/105 (34%), Positives = 60/105 (57%), Gaps = 3/105 (2%)
Frame = +3
Query: 570 WDVDLDAVEALADDKTVAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYDHY 749
W +D + E KT A+++ P NP G VF+R+ L + K +++I+DEVY+H
Sbjct: 184 WTIDFEQFEKAITSKTKAVIINTPHNPIGKVFTREELTTLGNICVKHNVVIISDEVYEHL 243
Query: 750 AFGDKPFVSMAEFA-EIVPVVL-LGAISKRWFVPGWRLGWMVTLD 878
F D F +A + EI + L +G+ K + GWR+GW+++L+
Sbjct: 244 YFTDS-FTRIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLN 287
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,771,599,260
Number of Sequences: 518415
Number of Extensions: 58771599260
Number of Successful Extensions: 389091298
Number of sequences better than 0.0: 0
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