BLASTX 7.6.2
Query= UN57212 /QuerySize=730
(729 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P93846|CP51_SORBI Obtusifoliol 14-alpha demethylase OS=Sorghu... 186 2e-046
sp|P93596|CP51_WHEAT Obtusifoliol 14-alpha demethylase (Fragment... 168 4e-041
sp|Q1ZXH9|CP51_DICDI Probable lanosterol 14-alpha demethylase OS... 103 2e-021
sp|Q17RH7|TPRXL_HUMAN Putative protein TPRXL OS=Homo sapiens GN=... 69 4e-011
sp|Q5IZM4|CP51_MYCVP Lanosterol 14-alpha demethylase OS=Mycobact... 60 1e-008
sp|P0A513|CP51_MYCBO Lanosterol 14-alpha demethylase OS=Mycobact... 59 4e-008
sp|P0A512|CP51_MYCTU Lanosterol 14-alpha demethylase OS=Mycobact... 59 4e-008
sp|P87179|WSC1_SCHPO Cell wall integrity and stress response com... 54 7e-007
sp|O94317|YH5D_SCHPO Uncharacterized serine-rich protein C215.13... 51 6e-006
sp|P32323|AGA1_YEAST A-agglutinin anchorage subunit OS=Saccharom... 51 8e-006
>sp|P93846|CP51_SORBI Obtusifoliol 14-alpha demethylase OS=Sorghum bicolor
GN=CYP51 PE=1 SV=1
Length = 492
Score = 186 bits (470), Expect = 2e-046
Identities = 89/151 (58%), Positives = 121/151 (80%), Gaps = 3/151 (1%)
Frame = +2
Query: 155 ELDSDKNLLKTGLVVIATLVLAKLIFSFFFKSDSKKKRLPPTLKAWPPLIGSLLRFLKGP 334
++ + L+ +V+AT++ KL+ S F+S KKRLPPT+ P++G L++F++GP
Sbjct: 5 DIPQQQRLMAGLALVVATVIFLKLLLS--FRSGGGKKRLPPTIPG-APVVGGLVKFMRGP 61
Query: 335 IVMLRDEYPNLGSVFTVNLLHKKMTFLIGPEVSAHFFKAPESDLSQQEVYQFNVPTFGPG 514
I M+R++Y LGSVFTV ++ +++TFLIGPEVSAHFFK E+++SQQEVY+FNVPTFGPG
Sbjct: 62 IPMIREQYAALGSVFTVPIITRRITFLIGPEVSAHFFKGNEAEMSQQEVYRFNVPTFGPG 121
Query: 515 VVFDVDYTVRQEQFRFFTEALRVNKLKGYVE 607
VVFDVDY+VRQEQFRFFTEALR NKL+ YV+
Sbjct: 122 VVFDVDYSVRQEQFRFFTEALRANKLRSYVD 152
Score = 80 bits (196), Expect = 1e-014
Identities = 35/37 (94%), Positives = 36/37 (97%)
Frame = +2
Query: 617 NRLPHIFKNPDSYDPDRFSPGREEDKAAGAFSYISFG 727
NRLPHI+KNPDSYDPDRF PGREEDKAAGAFSYISFG
Sbjct: 392 NRLPHIYKNPDSYDPDRFGPGREEDKAAGAFSYISFG 428
>sp|P93596|CP51_WHEAT Obtusifoliol 14-alpha demethylase (Fragment) OS=Triticum
aestivum GN=CYP51 PE=2 SV=1
Length = 453
Score = 168 bits (424), Expect = 4e-041
Identities = 80/112 (71%), Positives = 96/112 (85%), Gaps = 1/112 (0%)
Frame = +2
Query: 272 PPTLKAWPPLIGSLLRFLKGPIVMLRDEYPNLGSVFTVNLLHKKMTFLIGPEVSAHFFKA 451
PPT+ P++G LLRFL+GPI ++R EY LG VFTV +L +++TFLIGP+VSAHFFK+
Sbjct: 3 PPTIPG-APVVGGLLRFLRGPIPLIRAEYARLGPVFTVPILTRRITFLIGPDVSAHFFKS 61
Query: 452 PESDLSQQEVYQFNVPTFGPGVVFDVDYTVRQEQFRFFTEALRVNKLKGYVE 607
ESD+SQQEVY+FNVPTFGPGVVFDVDY VRQEQFRFFTEALR NKL+ YV+
Sbjct: 62 NESDMSQQEVYRFNVPTFGPGVVFDVDYQVRQEQFRFFTEALRANKLRSYVD 113
Score = 77 bits (188), Expect = 1e-013
Identities = 34/37 (91%), Positives = 35/37 (94%)
Frame = +2
Query: 617 NRLPHIFKNPDSYDPDRFSPGREEDKAAGAFSYISFG 727
NRLPHIFKNPDSYDPDRF+ GREEDK AGAFSYISFG
Sbjct: 353 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFG 389
>sp|Q1ZXH9|CP51_DICDI Probable lanosterol 14-alpha demethylase OS=Dictyostelium
discoideum GN=cyp51 PE=3 SV=1
Length = 466
Score = 103 bits (255), Expect = 2e-021
Identities = 54/132 (40%), Positives = 81/132 (61%), Gaps = 4/132 (3%)
Frame = +2
Query: 200 IATLVLAKLIFSFFFKSDSKKKRLPPTLKAWPPLIGSLLRFLKGPIVMLRDEYPNLGSVF 379
IA LV+A L+ F KS S +PP ++ P IG +F K P+ ++R+ Y LG +F
Sbjct: 5 IAVLVIAILVIFAFKKSPS---NIPPIVET-IPFIGCFYQFAKNPLQLVRNSYDRLGEIF 60
Query: 380 TVNLLHKKMTFLIGPEVSAHFFKAPESDLSQQEVYQFNVPTFGPGVVFDVDYTVRQEQFR 559
T++L+ KMTF++GPE A FF+ + +LS +E Y+F P FG GVV+D + + EQ R
Sbjct: 61 TLHLMGFKMTFVLGPEAQALFFRGTDEELSPKEAYRFVTPVFGKGVVYDSETEIMYEQLR 120
Query: 560 FFTEALRVNKLK 595
F L +++LK
Sbjct: 121 FVKNGLVLSQLK 132
>sp|Q17RH7|TPRXL_HUMAN Putative protein TPRXL OS=Homo sapiens GN=TPRXL PE=5
SV=2
Length = 258
Score = 69 bits (166), Expect = 4e-011
Identities = 51/120 (42%), Positives = 70/120 (58%), Gaps = 8/120 (6%)
Frame = +3
Query: 207 HSFSPNSSSPSSSNPTPKRSVSLPLSKHGHHSSEASSAS*KAPSSCSETSTPTSDPSSPS 386
HS S SSS S+S+P+ S S S +SS +SS+S + SS S +S+P+S SSPS
Sbjct: 78 HSSSSPSSSSSTSSPSSSSSSSSSSSPSSSNSSSSSSSSSPSSSSSSSSSSPSSSSSSPS 137
Query: 387 TSSTKR*PFSSAPKSPPISSKLPSLISASRKSTSSMSLLLALELSSTSTTPFARNSSGSS 566
+SS SS+ SP SS PS S+S S+SS S + SS+ ++P + NSS SS
Sbjct: 138 SSS------SSSSSSPSSSSSSPS--SSSSSSSSSSSSPSSSSPSSSGSSPSSSNSSPSS 189
Score = 68 bits (165), Expect = 5e-011
Identities = 51/123 (41%), Positives = 70/123 (56%), Gaps = 3/123 (2%)
Frame = +3
Query: 210 SFSPNSSSPSSSNPTPKRSVSLPLSKHGHHSSE-ASSAS*KAPSSCSETSTPTSDPSSPS 386
S S +SSSPSSSN + S S P S SS +SS+S + SS S +S+P+S SSPS
Sbjct: 96 SSSSSSSSPSSSNSSSSSSSSSPSSSSSSSSSSPSSSSSSPSSSSSSSSSSPSSSSSSPS 155
Query: 387 TSSTKR*PFSSAP--KSPPISSKLPSLISASRKSTSSMSLLLALELSSTSTTPFARNSSG 560
+SS+ SS+P SP S PS ++S S+SS + S S++P + +SS
Sbjct: 156 SSSSSSSSSSSSPSSSSPSSSGSSPSSSNSSPSSSSSSPSSSSSSPSPRSSSPSSSSSST 215
Query: 561 SSP 569
SSP
Sbjct: 216 SSP 218
Score = 65 bits (157), Expect = 4e-010
Identities = 49/125 (39%), Positives = 64/125 (51%), Gaps = 5/125 (4%)
Frame = +3
Query: 210 SFSPNSSSPSSSNPTPKRSVSLPLSKHGHHSSEASSAS*KAPSS-----CSETSTPTSDP 374
S S SSS SSS+ +P S S P S SS +SS S +PSS S S+P+S
Sbjct: 132 SSSSPSSSSSSSSSSPSSSSSSPSSSSSSSSSSSSSPSSSSPSSSGSSPSSSNSSPSSSS 191
Query: 375 SSPSTSSTKR*PFSSAPKSPPISSKLPSLISASRKSTSSMSLLLALELSSTSTTPFARNS 554
SSPS+SS+ P SS+P S S+ PS S S S SS S + ++ P + S
Sbjct: 192 SSPSSSSSSPSPRSSSPSSSSSSTSSPSTSSPSSSSPSSSSPSSSCPSAALGRRPQSPQS 251
Query: 555 SGSSP 569
S +P
Sbjct: 252 SHCAP 256
Score = 64 bits (153), Expect = 1e-009
Identities = 47/120 (39%), Positives = 63/120 (52%)
Frame = +3
Query: 210 SFSPNSSSPSSSNPTPKRSVSLPLSKHGHHSSEASSAS*KAPSSCSETSTPTSDPSSPST 389
S S SSS SSS+P+ S S P S S +SS+S + S S S+ +S SSPS+
Sbjct: 61 SSSSPSSSHSSSSPSSSHSSSSPSSSSSTSSPSSSSSSSSSSSPSSSNSSSSSSSSSPSS 120
Query: 390 SSTKR*PFSSAPKSPPISSKLPSLISASRKSTSSMSLLLALELSSTSTTPFARNSSGSSP 569
SS+ S+ S P SS S S S S+S S + SS+S + + +SSGSSP
Sbjct: 121 SSSSSSSSPSSSSSSPSSSSSSSSSSPSSSSSSPSSSSSSSSSSSSSPSSSSPSSSGSSP 180
Score = 63 bits (152), Expect = 2e-009
Identities = 51/121 (42%), Positives = 64/121 (52%), Gaps = 2/121 (1%)
Frame = +3
Query: 210 SFSPNSSSPSSSNPTPKRSVSLPLSKHGHHSSEASSAS*KAPSSCSETSTPTSDPSSPST 389
S S SSS SSS+ +P S S P S SS SS+S SS S +S+ +S PSS S
Sbjct: 114 SSSSPSSSSSSSSSSPSSSSSSPSSSSSSSSSSPSSSSSSPSSSSSSSSSSSSSPSSSSP 173
Query: 390 SSTKR*PFSSAPKSPPISSKLPSLISASRKSTSSMSLLLALELSSTST-TPFARNSSGSS 566
SS+ P SS+ SP SS PS S+S SS + SS ST +P + + S SS
Sbjct: 174 SSSGSSP-SSSNSSPSSSSSSPSSSSSSPSPRSSSPSSSSSSTSSPSTSSPSSSSPSSSS 232
Query: 567 P 569
P
Sbjct: 233 P 233
Score = 62 bits (150), Expect = 3e-009
Identities = 51/119 (42%), Positives = 69/119 (57%), Gaps = 7/119 (5%)
Frame = +3
Query: 210 SFSPNSSSPSSSNPTPKRSVSLPLSKHGHHSSEASSAS*KAPSSCSETSTPTSDPSSPST 389
S S SSS SSS+P+ S S P S H SS +SS+S +PSS S +S+ +S SS S+
Sbjct: 52 SSSIPSSSSSSSSPSSSHSSSSPSSSHS-SSSPSSSSSTSSPSSSSSSSSSSSPSSSNSS 110
Query: 390 SSTKR*PFSSAPKSPPISSKLPSLISASRKSTSSMSLLLALELSSTSTTPFARNSSGSS 566
SS+ SS S SS PS S+S S+SS S + SS+S++P + +SS SS
Sbjct: 111 SSSSS---SSPSSSSSSSSSSPSSSSSSPSSSSSSS---SSSPSSSSSSPSSSSSSSSS 163
>sp|Q5IZM4|CP51_MYCVP Lanosterol 14-alpha demethylase OS=Mycobacterium
vanbaalenii (strain DSM 7251 / PYR-1) GN=cyp51 PE=3 SV=1
Length = 452
Score = 60 bits (144), Expect = 1e-008
Identities = 36/99 (36%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
Frame = +2
Query: 305 GSLLRFLKGPIVMLRDEYPNLGSVFTVNLLHKKMTFLIGPEVSAHFFKAPESDLSQQEVY 484
G L F PI +++ G V L K++ L G E + FF++ +S+L+Q E Y
Sbjct: 18 GHLEEFRTDPIGLMKRVREECGDVGWFQLADKQVILLSGAEANEFFFRSSDSELNQAEAY 77
Query: 485 QFNVPTFGPGVVFDVDYTVRQEQFRFFTEALRVNKLKGY 601
F P FG GVVFD D R E ALR +KG+
Sbjct: 78 PFMTPIFGEGVVFDADPERRAEMLH--NTALRGEHMKGH 114
>sp|P0A513|CP51_MYCBO Lanosterol 14-alpha demethylase OS=Mycobacterium bovis
GN=cyp51 PE=3 SV=1
Length = 451
Score = 59 bits (140), Expect = 4e-008
Identities = 35/99 (35%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Frame = +2
Query: 305 GSLLRFLKGPIVMLRDEYPNLGSVFTVNLLHKKMTFLIGPEVSAHFFKAPESDLSQQEVY 484
G L F PI +++ G V T L K++ L G + FF+A + DL Q + Y
Sbjct: 17 GHLEEFRTDPIGLMQRVRDECGDVGTFQLAGKQVVLLSGSHANEFFFRAGDDDLDQAKAY 76
Query: 485 QFNVPTFGPGVVFDVDYTVRQEQFRFFTEALRVNKLKGY 601
F P FG GVVFD R+E ALR ++KG+
Sbjct: 77 PFMTPIFGEGVVFDASPERRKEMLH--NAALRGEQMKGH 113
>sp|P0A512|CP51_MYCTU Lanosterol 14-alpha demethylase OS=Mycobacterium
tuberculosis GN=cyp51 PE=1 SV=1
Length = 451
Score = 59 bits (140), Expect = 4e-008
Identities = 35/99 (35%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Frame = +2
Query: 305 GSLLRFLKGPIVMLRDEYPNLGSVFTVNLLHKKMTFLIGPEVSAHFFKAPESDLSQQEVY 484
G L F PI +++ G V T L K++ L G + FF+A + DL Q + Y
Sbjct: 17 GHLEEFRTDPIGLMQRVRDECGDVGTFQLAGKQVVLLSGSHANEFFFRAGDDDLDQAKAY 76
Query: 485 QFNVPTFGPGVVFDVDYTVRQEQFRFFTEALRVNKLKGY 601
F P FG GVVFD R+E ALR ++KG+
Sbjct: 77 PFMTPIFGEGVVFDASPERRKEMLH--NAALRGEQMKGH 113
>sp|P87179|WSC1_SCHPO Cell wall integrity and stress response component 1
OS=Schizosaccharomyces pombe GN=wsc1 PE=1 SV=3
Length = 374
Score = 54 bits (129), Expect = 7e-007
Identities = 44/117 (37%), Positives = 61/117 (52%), Gaps = 4/117 (3%)
Frame = +3
Query: 216 SPNSSSPSSSNPTPKRSVSLPLSKHGHHSSEASSAS*KAPSSCSETSTPTSDPSSPSTSS 395
SP+SSS SSS+ + S S S SS +SS+S + SS S +S+ +S S P TSS
Sbjct: 154 SPSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSVPITSS 213
Query: 396 TKR*PFSSAPKSPPISSKLPSLISASRKSTSSMSLLLALELSSTSTTPFARNSSGSS 566
T SS+ S SS S+S +T S S +S+ + TP + +SS SS
Sbjct: 214 TSSSHSSSSSSSSSSSSSSRPSSSSSFITTMSSSTF----ISTVTVTPSSSSSSTSS 266
>sp|O94317|YH5D_SCHPO Uncharacterized serine-rich protein C215.13
OS=Schizosaccharomyces pombe GN=SPBC215.13 PE=1 SV=1
Length = 534
Score = 51 bits (121), Expect = 6e-006
Identities = 43/120 (35%), Positives = 65/120 (54%), Gaps = 1/120 (0%)
Frame = +3
Query: 210 SFSPNSSSPSSSNPTPKRSVSLPLSKHGHHSSEASSAS*KAPSSCSETSTPTSDPSSPST 389
S S +SSSP+S++ T S S S S+ +SS+S + S + +S+ S SS S+
Sbjct: 275 SSSSSSSSPTSTSSTISSSSSSSSSPTSTSSTISSSSSSSSSFSSTLSSSSMSSSSSFSS 334
Query: 390 SSTKR*PFSSAPKSPPISSKLPSLISASRKSTSSMSLLLALELSSTSTTPFARNSSGSSP 569
S T S+ S P SS S S+S KS+SS S ++ S++S+T + +SS S P
Sbjct: 335 SPTSSSSTISSSSSSPSSSSFSSTTSSS-KSSSSFSSTVSSSSSTSSSTLTSSSSSSSRP 393
>sp|P32323|AGA1_YEAST A-agglutinin anchorage subunit OS=Saccharomyces cerevisiae
GN=AGA1 PE=1 SV=1
Length = 725
Score = 51 bits (120), Expect = 8e-006
Identities = 37/113 (32%), Positives = 58/113 (51%)
Frame = +3
Query: 228 SSPSSSNPTPKRSVSLPLSKHGHHSSEASSAS*KAPSSCSETSTPTSDPSSPSTSSTKR* 407
SS +SSNPT S S +S +S+++ + +S S +ST TS S+ ++ S+
Sbjct: 174 SSTTSSNPTTTSLSSTSTSPSSTSTSPSSTSTSSSSTSTSSSSTSTSSSSTSTSPSSTST 233
Query: 408 PFSSAPKSPPISSKLPSLISASRKSTSSMSLLLALELSSTSTTPFARNSSGSS 566
S S +S S S S STS+ + SSTST+P ++++S SS
Sbjct: 234 SSSLTSTSSSSTSTSQSSTSTSSSSTSTSPSSTSTSSSSTSTSPSSKSTSASS 286
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 204,589,345,658
Number of Sequences: 518415
Number of Extensions: 204589345658
Number of Successful Extensions: 1266473598
Number of sequences better than 0.0: 0
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