BLASTX 7.6.2
Query= RU01406 /QuerySize=1105
(1104 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q71VM4|IMA1A_ORYSJ Importin subunit alpha-1a OS=Oryza sativa ... 531 4e-150
sp|Q96321|IMA1_ARATH Importin subunit alpha-1 OS=Arabidopsis tha... 528 3e-149
sp|O22478|IMA_SOLLC Importin subunit alpha OS=Solanum lycopersic... 517 5e-146
sp|Q9SLX0|IMA1B_ORYSJ Importin subunit alpha-1b OS=Oryza sativa ... 500 6e-141
sp|O04294|IMA2_ARATH Importin subunit alpha-2 OS=Arabidopsis tha... 449 2e-125
sp|Q76P29|IMAB_DICDI Importin subunit alpha-B OS=Dictyostelium d... 367 1e-100
sp|O14063|IMA1_SCHPO Importin subunit alpha-1 OS=Schizosaccharom... 312 3e-084
sp|O35345|IMA7_MOUSE Importin subunit alpha-7 OS=Mus musculus GN... 304 1e-081
sp|Q0V7M0|IMA7_BOVIN Importin subunit alpha-7 OS=Bos taurus GN=K... 302 4e-081
sp|O60684|IMA7_HUMAN Importin subunit alpha-7 OS=Homo sapiens GN... 300 1e-080
sp|Q5RBV0|IMA7_PONAB Importin subunit alpha-7 OS=Pongo abelii GN... 300 1e-080
sp|O94374|IMA2_SCHPO Importin subunit alpha-2 OS=Schizosaccharom... 299 4e-080
sp|Q02821|IMA1_YEAST Importin subunit alpha OS=Saccharomyces cer... 275 3e-073
sp|P52170|IMA1_XENLA Importin subunit alpha-1 OS=Xenopus laevis ... 274 8e-073
sp|Q5ZML1|IMA1_CHICK Importin subunit alpha-1 OS=Gallus gallus G... 273 2e-072
sp|O15131|IMA5_HUMAN Importin subunit alpha-6 OS=Homo sapiens GN... 272 4e-072
sp|P52293|IMA2_MOUSE Importin subunit alpha-2 OS=Mus musculus GN... 270 2e-071
sp|Q56R16|IMA5_RAT Importin subunit alpha-6 OS=Rattus norvegicus... 268 7e-071
sp|A2VE08|IMA1_BOVIN Importin subunit alpha-1 OS=Bos taurus GN=K... 267 9e-071
sp|P52171|IMA2_XENLA Importin subunit alpha-2 OS=Xenopus laevis ... 267 9e-071
sp|P52294|IMA1_HUMAN Importin subunit alpha-1 OS=Homo sapiens GN... 267 1e-070
sp|Q5R909|IMA1_PONAB Importin subunit alpha-1 OS=Pongo abelii GN... 267 1e-070
sp|P52292|IMA2_HUMAN Importin subunit alpha-2 OS=Homo sapiens GN... 267 1e-070
sp|P83953|IMA1_RAT Importin subunit alpha-1 OS=Rattus norvegicus... 266 2e-070
sp|Q60960|IMA1_MOUSE Importin subunit alpha-1 OS=Mus musculus GN... 264 1e-069
sp|O35344|IMA3_MOUSE Importin subunit alpha-3 OS=Mus musculus GN... 259 3e-068
sp|P52295|IMA_DROME Importin subunit alpha OS=Drosophila melanog... 258 4e-068
sp|O00505|IMA3_HUMAN Importin subunit alpha-3 OS=Homo sapiens GN... 258 7e-068
sp|A9QM74|IMA8_HUMAN Importin subunit alpha-8 OS=Homo sapiens GN... 256 2e-067
sp|O35343|IMA4_MOUSE Importin subunit alpha-4 OS=Mus musculus GN... 255 4e-067
>sp|Q71VM4|IMA1A_ORYSJ Importin subunit alpha-1a OS=Oryza sativa subsp. japonica
GN=Os01g0253300 PE=1 SV=2
Length = 526
Score = 531 bits (1366), Expect = 4e-150
Identities = 264/309 (85%), Positives = 288/309 (93%)
Frame = -3
Query: 928 MSLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPA 749
MSLRP+ R EVRRNRYKVAVDAEEGRRRREDNMVEIRKS+REESLLKKRREGLQAQ
Sbjct: 1 MSLRPSERVEVRRNRYKVAVDAEEGRRRREDNMVEIRKSRREESLLKKRREGLQAQAPVP 60
Query: 748 SVQPPNLEKKLESLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPRF 569
+ ++KKLESLP+M+ GV+S ++ LQLEATTQFRKLLSIERSPPIEEVIQ+GVVPRF
Sbjct: 61 ASAATGVDKKLESLPAMIGGVYSDDNNLQLEATTQFRKLLSIERSPPIEEVIQSGVVPRF 120
Query: 568 VEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVW 389
V+FL RED+PQLQFEAAWALTNIASGTS+NT+VVIDHGAVPIFVKLL S SDDVREQAVW
Sbjct: 121 VQFLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVREQAVW 180
Query: 388 ALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGKPQPQFDQV 209
ALGNVAGDSP+CRDLVL++GAL+PLLAQLNEH KLSMLRNATWTLSNFCRGKPQP F+Q
Sbjct: 181 ALGNVAGDSPKCRDLVLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGKPQPSFEQT 240
Query: 208 KPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAV 29
+PALPAL RL+HSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLV+LLLHPSP+V
Sbjct: 241 RPALPALARLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVELLLHPSPSV 300
Query: 28 LIPALRTVG 2
LIPALRTVG
Sbjct: 301 LIPALRTVG 309
>sp|Q96321|IMA1_ARATH Importin subunit alpha-1 OS=Arabidopsis thaliana GN=KAP1
PE=2 SV=2
Length = 532
Score = 528 bits (1359), Expect = 3e-149
Identities = 265/309 (85%), Positives = 286/309 (92%)
Frame = -3
Query: 928 MSLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPA 749
MSLRPNA+TEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESL+KKRREG+QA Q
Sbjct: 1 MSLRPNAKTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLMKKRREGMQALQGFP 60
Query: 748 SVQPPNLEKKLESLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPRF 569
S +++KKL+SL MVAGVWS + ALQLE+TTQFRKLLSIERSPPIEEVI AGVVPRF
Sbjct: 61 SASAASVDKKLDSLKDMVAGVWSDDPALQLESTTQFRKLLSIERSPPIEEVISAGVVPRF 120
Query: 568 VEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVW 389
VEFL +EDYP +QFEAAWALTNIASGTSD+T+VVIDH AVPIFV+LLASPSDDVREQAVW
Sbjct: 121 VEFLKKEDYPAIQFEAAWALTNIASGTSDHTKVVIDHNAVPIFVQLLASPSDDVREQAVW 180
Query: 388 ALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGKPQPQFDQV 209
ALGNVAGDSPRCRDLVL GAL+PLL QLNEHAKLSMLRNATWTLSNFCRGKPQP FDQV
Sbjct: 181 ALGNVAGDSPRCRDLVLGCGALLPLLNQLNEHAKLSMLRNATWTLSNFCRGKPQPHFDQV 240
Query: 208 KPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAV 29
KPALPALERL+HS+DEEVLTDACWALSYLSDGTNDKIQ VI+AGV P+LV+LLLH SP+V
Sbjct: 241 KPALPALERLIHSDDEEVLTDACWALSYLSDGTNDKIQTVIQAGVVPKLVELLLHHSPSV 300
Query: 28 LIPALRTVG 2
LIPALRTVG
Sbjct: 301 LIPALRTVG 309
>sp|O22478|IMA_SOLLC Importin subunit alpha OS=Solanum lycopersicum PE=2 SV=2
Length = 527
Score = 517 bits (1331), Expect = 5e-146
Identities = 257/310 (82%), Positives = 287/310 (92%), Gaps = 1/310 (0%)
Frame = -3
Query: 928 MSLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREG-LQAQQFP 752
MSLRPN+RTE RR+RYKVAVDAEEGRRRREDNMVEIRK+KREE+LLKKRREG LQAQQFP
Sbjct: 1 MSLRPNSRTEARRSRYKVAVDAEEGRRRREDNMVEIRKNKREENLLKKRREGLLQAQQFP 60
Query: 751 ASVQPPNLEKKLESLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPR 572
++ +L+KKLE+LP ++AGVWS +S+LQLE TTQFRKLLSIER+PPIEEVIQ+GVVPR
Sbjct: 61 STAAVSHLDKKLETLPELIAGVWSDDSSLQLECTTQFRKLLSIERNPPIEEVIQSGVVPR 120
Query: 571 FVEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAV 392
FVEFL R+DYPQLQFEAAWALTNIASGTS+NT+VVID+G+VPIF++LL+SPSDDVREQAV
Sbjct: 121 FVEFLARDDYPQLQFEAAWALTNIASGTSENTKVVIDYGSVPIFIRLLSSPSDDVREQAV 180
Query: 391 WALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGKPQPQFDQ 212
WALGN+AGDSP+ RDLVL GAL+ LLAQ NE AKLSMLRNATWTLSNFCRGKPQP F+Q
Sbjct: 181 WALGNIAGDSPKYRDLVLGHGALVALLAQFNEQAKLSMLRNATWTLSNFCRGKPQPLFEQ 240
Query: 211 VKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPA 32
K ALP L RL+HSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVC RLV+LLLH SP+
Sbjct: 241 TKAALPTLGRLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCSRLVELLLHSSPS 300
Query: 31 VLIPALRTVG 2
VLIPALRTVG
Sbjct: 301 VLIPALRTVG 310
>sp|Q9SLX0|IMA1B_ORYSJ Importin subunit alpha-1b OS=Oryza sativa subsp. japonica
GN=Os05g0155500 PE=1 SV=2
Length = 534
Score = 500 bits (1287), Expect = 6e-141
Identities = 254/315 (80%), Positives = 280/315 (88%), Gaps = 6/315 (1%)
Frame = -3
Query: 928 MSLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPA 749
MSLRP+ R EVRR+RYKVAVDA+EGRRRREDNMVEIRKS+REESLLKKRR+GL A A
Sbjct: 1 MSLRPSERAEVRRSRYKVAVDADEGRRRREDNMVEIRKSRREESLLKKRRDGLPAAAAAA 60
Query: 748 SVQPP------NLEKKLESLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQA 587
+ P L++KLE LP+MV V S +SA+QLEATTQFRKLLSIERSPPIEEVI
Sbjct: 61 AAASPLLAHSSALQQKLEGLPAMVQAVQSDDSAVQLEATTQFRKLLSIERSPPIEEVINT 120
Query: 586 GVVPRFVEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDV 407
GVVPRF+ FL REDYPQLQFEAAWALTNIASGTSDNT+VV++ GAVPIFVKLL+SPS+DV
Sbjct: 121 GVVPRFIAFLQREDYPQLQFEAAWALTNIASGTSDNTKVVVESGAVPIFVKLLSSPSEDV 180
Query: 406 REQAVWALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGKPQ 227
REQAVWALGNVAGDSP+CRDLVL+SG L PLL QLNEHAKLSMLRNATWTLSNFCRGKPQ
Sbjct: 181 REQAVWALGNVAGDSPKCRDLVLASGGLYPLLQQLNEHAKLSMLRNATWTLSNFCRGKPQ 240
Query: 226 PQFDQVKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLL 47
P F+QVKPAL AL+RL+HS DEEVLTDACWALSYLSDGTNDKIQAVIE+GV PRLV+LL+
Sbjct: 241 PNFEQVKPALSALQRLIHSQDEEVLTDACWALSYLSDGTNDKIQAVIESGVFPRLVELLM 300
Query: 46 HPSPAVLIPALRTVG 2
HPS +VLIPALRTVG
Sbjct: 301 HPSASVLIPALRTVG 315
>sp|O04294|IMA2_ARATH Importin subunit alpha-2 OS=Arabidopsis thaliana GN=KAP2
PE=1 SV=2
Length = 531
Score = 449 bits (1153), Expect = 2e-125
Identities = 229/314 (72%), Positives = 265/314 (84%), Gaps = 7/314 (2%)
Frame = -3
Query: 928 MSLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKR-----REGLQA 764
MSLRP+A+TEVRRNRYKVAVDAEEGRRRREDN+VEIRK+KREE+L KKR G
Sbjct: 1 MSLRPSAKTEVRRNRYKVAVDAEEGRRRREDNLVEIRKNKREENLQKKRFTSSMAFGSAT 60
Query: 763 QQFPASVQPPNLEKKLESLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAG 584
Q + N K ++LP+MVAG+WS +S QLEAT RKLLSIE++PPI EV+Q+G
Sbjct: 61 GQTEQDLSSANQLK--DNLPAMVAGIWSEDSNSQLEATNLLRKLLSIEQNPPINEVVQSG 118
Query: 583 VVPRFVEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVR 404
VVPR V+FL R+D+P+LQFEAAWALTNIASGTS+NT V+I+ GAVPIF++LL+S S+DVR
Sbjct: 119 VVPRVVKFLSRDDFPKLQFEAAWALTNIASGTSENTNVIIESGAVPIFIQLLSSASEDVR 178
Query: 403 EQAVWALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGKPQP 224
EQAVWALGNVAGDSP+CRDLVLS GA+ PLL+Q NE+ KLSMLRNATWTLSNFCRGKP P
Sbjct: 179 EQAVWALGNVAGDSPKCRDLVLSYGAMTPLLSQFNENTKLSMLRNATWTLSNFCRGKPPP 238
Query: 223 QFDQVKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLH 44
F+Q +PALP LERLV S DEEVLTDACWALSYLSD +NDKIQAVIEAGV PRL+QLL H
Sbjct: 239 AFEQTQPALPVLERLVQSMDEEVLTDACWALSYLSDNSNDKIQAVIEAGVVPRLIQLLGH 298
Query: 43 PSPAVLIPALRTVG 2
SP+VLIPALRT+G
Sbjct: 299 SSPSVLIPALRTIG 312
>sp|Q76P29|IMAB_DICDI Importin subunit alpha-B OS=Dictyostelium discoideum
GN=DDB_G0272318 PE=3 SV=1
Length = 516
Score = 367 bits (940), Expect = 1e-100
Identities = 187/305 (61%), Positives = 240/305 (78%), Gaps = 4/305 (1%)
Frame = -3
Query: 910 ARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPASVQPPN 731
++ E R+++YK ++D++E RR+RE+ + IRK+KREESLLKKR + + P V
Sbjct: 4 SKQETRKSQYKKSIDSDESRRKREEASLSIRKNKREESLLKKRTQAVPGST-PVKVD-SL 61
Query: 730 LEKKLESLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPRFVEFLVR 551
+ ++LE LPS+VA + S L L++TT FRKLLSIE+SPPIEEVI+ G+VPR V+FL
Sbjct: 62 INQRLEQLPSLVAEINSENPDLILKSTTAFRKLLSIEKSPPIEEVIKTGIVPRLVKFLYM 121
Query: 550 EDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVA 371
+D+PQLQFEAAWALTNIASGT + TRVVI++GA+ +FV LL+SP DDVREQAVWALGN+A
Sbjct: 122 QDFPQLQFEAAWALTNIASGTPEQTRVVIENGAIQVFVLLLSSPHDDVREQAVWALGNIA 181
Query: 370 GDSPRCRDLVLSSGALMPLLAQLNEHA--KLSMLRNATWTLSNFCRGKPQPQFDQVKPAL 197
GDS CRDLVLS AL PLL+ L A K+SM+RNATWTLSNFCRGKPQP F+ V+ +L
Sbjct: 182 GDSHYCRDLVLSHNALPPLLSLLQNPAAIKVSMVRNATWTLSNFCRGKPQPPFEIVRASL 241
Query: 196 PALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPA 17
P L +L++ DEEVL DACWALSYLSDG+N++IQ VI+A VC ++V+LL HP+ AV PA
Sbjct: 242 PVLAKLIYYQDEEVLIDACWALSYLSDGSNERIQEVIDAKVCRKMVELLGHPTIAVQTPA 301
Query: 16 LRTVG 2
LRT+G
Sbjct: 302 LRTIG 306
>sp|O14063|IMA1_SCHPO Importin subunit alpha-1 OS=Schizosaccharomyces pombe
GN=cut15 PE=1 SV=1
Length = 542
Score = 312 bits (798), Expect = 3e-084
Identities = 170/310 (54%), Positives = 220/310 (70%), Gaps = 14/310 (4%)
Frame = -3
Query: 901 EVRRNRY--KVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPASVQPP-- 734
E RR Y K A+E RRRRE +EIRK KREE+L K+R L Q PA P
Sbjct: 10 EHRRQNYKGKGTFQADELRRRRETQQIEIRKQKREENLNKRR--NLVDVQEPAEETIPLE 67
Query: 733 -----NLEKKLESLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPRF 569
+LE +L+ LP ++ ++S + Q++AT +FRK LS E +PPI++VI AGVVPRF
Sbjct: 68 QDKENDLELELQ-LPDLLKALYSDDIEAQIQATAKFRKALSKETNPPIQKVIDAGVVPRF 126
Query: 568 VEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVW 389
VEFL E+ L+FEA+WALTN+ASG+S+ T VV++ AVP+FV LL+S DVREQAVW
Sbjct: 127 VEFLSHEN-NLLKFEASWALTNVASGSSNQTHVVVEANAVPVFVSLLSSSEQDVREQAVW 185
Query: 388 ALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQ 212
ALGN+AGDSP CRD VL G L PLL + + +LSMLRN+TWTLSN CRGK PQP ++
Sbjct: 186 ALGNIAGDSPMCRDHVLQCGVLEPLLNIIESNRRLSMLRNSTWTLSNMCRGKNPQPDWNS 245
Query: 211 VKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPA 32
+ +P L +L+++ DE+VL DA WA+SYLSDG N+KIQA+I+AG+ RLV+LL+HPS
Sbjct: 246 ISQVIPVLSKLIYTLDEDVLVDALWAISYLSDGANEKIQAIIDAGIPRRLVELLMHPSAQ 305
Query: 31 VLIPALRTVG 2
V PALR+VG
Sbjct: 306 VQTPALRSVG 315
>sp|O35345|IMA7_MOUSE Importin subunit alpha-7 OS=Mus musculus GN=Kpna6 PE=1
SV=2
Length = 536
Score = 304 bits (776), Expect = 1e-081
Identities = 168/299 (56%), Positives = 210/299 (70%), Gaps = 8/299 (2%)
Frame = -3
Query: 874 AVDAEEGRRRREDNMVEIRKSKREESLLKKRREGL---QAQQFPASVQPPNLEKKL-ESL 707
A++ EE RRRRE+ +++RK KRE+ L K+R L +A F + + + ES+
Sbjct: 21 ALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESV 80
Query: 706 --PSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQA-GVVPRFVEFLVREDYPQ 536
MV ++S +S LQL T +FRKLLS E SPPI+EVI GVV RFVEFL R +
Sbjct: 81 ITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPGVVDRFVEFLKRNENCT 140
Query: 535 LQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVAGDSPR 356
LQFEAAWALTNIASGTS T++VI+ GAVPIF++LL S +DV+EQAVWALGN+AGDS
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSL 200
Query: 355 CRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPALPALERL 179
CRD VL+ L PLL L + +L+M RNA W LSN CRGK P P+F +V P LP L RL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRL 260
Query: 178 VHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPALRTVG 2
+ S+D ++L DACWALSYLSDG N+KIQAVI++GVC RLV+LL+H V PALR VG
Sbjct: 261 LFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVG 319
>sp|Q0V7M0|IMA7_BOVIN Importin subunit alpha-7 OS=Bos taurus GN=KPNA6 PE=2 SV=1
Length = 536
Score = 302 bits (771), Expect = 4e-081
Identities = 167/299 (55%), Positives = 209/299 (69%), Gaps = 8/299 (2%)
Frame = -3
Query: 874 AVDAEEGRRRREDNMVEIRKSKREESLLKKRREGL---QAQQFPASVQPPNLEKKL-ESL 707
A++ EE RRRRE+ +++RK KRE+ L K+R L +A F + + + ES+
Sbjct: 21 ALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESV 80
Query: 706 --PSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQA-GVVPRFVEFLVREDYPQ 536
MV ++S + LQL T +FRKLLS E SPPI+EVI GVV RFVEFL R +
Sbjct: 81 ITREMVEMLFSDDPDLQLATTQKFRKLLSKEPSPPIDEVINTPGVVDRFVEFLKRNENCT 140
Query: 535 LQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVAGDSPR 356
LQFEAAWALTNIASGTS T++VI+ GAVPIF++LL S +DV+EQAVWALGN+AGDS
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Query: 355 CRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPALPALERL 179
CRD VL+ L PLL L + +L+M RNA W LSN CRGK P P+F +V P LP L RL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRL 260
Query: 178 VHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPALRTVG 2
+ S+D ++L DACWALSYLSDG N+KIQAVI++GVC RLV+LL+H V PALR VG
Sbjct: 261 LFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDNKVASPALRAVG 319
>sp|O60684|IMA7_HUMAN Importin subunit alpha-7 OS=Homo sapiens GN=KPNA6 PE=1
SV=1
Length = 536
Score = 300 bits (767), Expect = 1e-080
Identities = 167/299 (55%), Positives = 209/299 (69%), Gaps = 8/299 (2%)
Frame = -3
Query: 874 AVDAEEGRRRREDNMVEIRKSKREESLLKKRREGL---QAQQFPASVQPPNLEKKL-ESL 707
A++ EE RRRRE+ +++RK KRE+ L K+R L +A F + + + ES+
Sbjct: 21 ALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESV 80
Query: 706 --PSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQA-GVVPRFVEFLVREDYPQ 536
MV ++S +S LQL T +FRKLLS E SPPI+EVI VV RFVEFL R +
Sbjct: 81 ITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCT 140
Query: 535 LQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVAGDSPR 356
LQFEAAWALTNIASGTS T++VI+ GAVPIF++LL S +DV+EQAVWALGN+AGDS
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Query: 355 CRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPALPALERL 179
CRD VL+ L PLL L + +L+M RNA W LSN CRGK P P+F +V P LP L RL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRL 260
Query: 178 VHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPALRTVG 2
+ S+D ++L DACWALSYLSDG N+KIQAVI++GVC RLV+LL+H V PALR VG
Sbjct: 261 LFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVG 319
>sp|Q5RBV0|IMA7_PONAB Importin subunit alpha-7 OS=Pongo abelii GN=KPNA6 PE=2
SV=1
Length = 536
Score = 300 bits (767), Expect = 1e-080
Identities = 167/299 (55%), Positives = 209/299 (69%), Gaps = 8/299 (2%)
Frame = -3
Query: 874 AVDAEEGRRRREDNMVEIRKSKREESLLKKRREGL---QAQQFPASVQPPNLEKKL-ESL 707
A++ EE RRRRE+ +++RK KRE+ L K+R L +A F + + + ES+
Sbjct: 21 ALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESV 80
Query: 706 --PSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQA-GVVPRFVEFLVREDYPQ 536
MV ++S +S LQL T +FRKLLS E SPPI+EVI VV RFVEFL R +
Sbjct: 81 ITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCT 140
Query: 535 LQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVAGDSPR 356
LQFEAAWALTNIASGTS T++VI+ GAVPIF++LL S +DV+EQAVWALGN+AGDS
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Query: 355 CRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPALPALERL 179
CRD VL+ L PLL L + +L+M RNA W LSN CRGK P P+F +V P LP L RL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRL 260
Query: 178 VHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPALRTVG 2
+ S+D ++L DACWALSYLSDG N+KIQAVI++GVC RLV+LL+H V PALR VG
Sbjct: 261 LFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVG 319
>sp|O94374|IMA2_SCHPO Importin subunit alpha-2 OS=Schizosaccharomyces pombe
GN=imp1 PE=1 SV=1
Length = 539
Score = 299 bits (763), Expect = 4e-080
Identities = 161/304 (52%), Positives = 206/304 (67%), Gaps = 9/304 (2%)
Frame = -3
Query: 892 RNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKR------REGLQAQQFPASVQPPN 731
R + K A+E RR+RE+ +EIRK KREESL K+R + + ++ Q
Sbjct: 12 RFKSKGVFKADELRRQREEQQIEIRKQKREESLNKRRNLNAVLQNDIDVEEEADQSQVQM 71
Query: 730 LEKKLESLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPRFVEFLVR 551
++ + P + A V S + LQL A T+FRK LS E PPI++VI GVV RFV+FL
Sbjct: 72 EQQMKDEFPKLTADVMSDDIELQLGAVTKFRKYLSKETHPPIDQVIACGVVDRFVQFLES 131
Query: 550 EDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVA 371
E + LQFEAAWALTNIASGT+D TR+V+D GAVP F++LL+SP DVREQ VWALGN+A
Sbjct: 132 EHH-LLQFEAAWALTNIASGTTDQTRIVVDSGAVPRFIQLLSSPEKDVREQVVWALGNIA 190
Query: 370 GDSPRCRDLVLSSGALMPLLAQLNEHAK-LSMLRNATWTLSNFCRGK-PQPQFDQVKPAL 197
GDS CRD VL +G L PLL L A +SMLRNATWTLSN CRGK P P + + A+
Sbjct: 191 GDSSACRDYVLGNGVLQPLLNILQSSASDVSMLRNATWTLSNLCRGKNPPPNWSTISVAV 250
Query: 196 PALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPA 17
P L +L++S D E++ DACWA+SYLSDG N+KI A+++ G PRLV+LL PS + PA
Sbjct: 251 PILAKLLYSEDVEIIVDACWAISYLSDGPNEKIGAILDVGCAPRLVELLSSPSVNIQTPA 310
Query: 16 LRTV 5
LR+V
Sbjct: 311 LRSV 314
>sp|Q02821|IMA1_YEAST Importin subunit alpha OS=Saccharomyces cerevisiae GN=SRP1
PE=1 SV=1
Length = 542
Score = 275 bits (703), Expect = 3e-073
Identities = 158/312 (50%), Positives = 203/312 (65%), Gaps = 14/312 (4%)
Frame = -3
Query: 901 EVRRNRY--KVAVDAEEGRRRREDNMVEIRKSKREESLLKKRR--------EGLQAQQFP 752
E RR + K A+E RRRR+ VE+RK+KR+E+L K+R + + +
Sbjct: 15 EYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDESS 74
Query: 751 ASVQPPNLEKKLESLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPR 572
S + + LP M + S + QL AT +FR++LS E PPI+ VIQAGVVPR
Sbjct: 75 VSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPR 134
Query: 571 FVEFLVREDYPQ-LQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQA 395
VEF+ RE+ P+ LQ EAAWALTNIASGTS T+VV+D AVP+F++LL + S +V+EQA
Sbjct: 135 LVEFM-RENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQA 193
Query: 394 VWALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRG-KPQPQF 218
+WALGNVAGDS RD VL A+ P+L N + K S++R ATWTLSN CRG KPQP +
Sbjct: 194 IWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN-KPSLIRTATWTLSNLCRGKKPQPDW 252
Query: 217 DQVKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPS 38
V ALP L +L++S D E L DACWA+SYLSDG + IQAVI+ + RLV+LL H S
Sbjct: 253 SVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHES 312
Query: 37 PAVLIPALRTVG 2
V PALR VG
Sbjct: 313 TLVQTPALRAVG 324
>sp|P52170|IMA1_XENLA Importin subunit alpha-1 OS=Xenopus laevis GN=kpna1 PE=1
SV=2
Length = 522
Score = 274 bits (700), Expect = 8e-073
Identities = 141/297 (47%), Positives = 196/297 (65%), Gaps = 13/297 (4%)
Frame = -3
Query: 868 DAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPA-------SVQPPNLEKKLES 710
D E RRRR + VE+RK+K++E +LK+R L + + SVQ P L S
Sbjct: 20 DTAELRRRRVEVSVELRKAKKDEQILKRRNVCLPEELILSPEKNAMQSVQVPPL-----S 74
Query: 709 LPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPRFVEFLVREDYPQLQ 530
L +V G+ S + +L T RK+LS ER+PP+ ++I+AG++P+ VEFL R D LQ
Sbjct: 75 LEEIVQGMNSGDPENELRCTQAARKMLSRERNPPLNDIIEAGLIPKLVEFLSRHDNSTLQ 134
Query: 529 FEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVAGDSPRCR 350
FEAAWALTNIASGTSD T+ V+D GA+P F+ L++SP + EQAVWALGN+AGD P R
Sbjct: 135 FEAAWALTNIASGTSDQTKSVVDGGAIPAFISLISSPHLHISEQAVWALGNIAGDGPLYR 194
Query: 349 DLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPALPALERLVH 173
D +++ + PLLA +N L LRN TW LSN CR K P P V LP L +L+H
Sbjct: 195 DALINCNVIPPLLALVNPQTPLGYLRNITWMLSNLCRNKNPYPPMSAVLQILPVLTQLMH 254
Query: 172 SNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPALRTVG 2
+D+++L+D CWA+SYL+DG+ND+I V++ G+ RL+QL+ P +++ P+LRTVG
Sbjct: 255 HDDKDILSDTCWAMSYLTDGSNDRIDVVVKTGIVDRLIQLMYSPELSIVTPSLRTVG 311
>sp|Q5ZML1|IMA1_CHICK Importin subunit alpha-1 OS=Gallus gallus GN=KPNA1 PE=2
SV=1
Length = 538
Score = 273 bits (696), Expect = 2e-072
Identities = 158/312 (50%), Positives = 203/312 (65%), Gaps = 12/312 (3%)
Frame = -3
Query: 925 SLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPAS 746
SL P+ E+RR R + + +++RE+ + + R E ++ E + +
Sbjct: 18 SLNPD---EMRRRREEEGLQLR--KQKREEQLFKRRNVATAE---EEAEEEVMSDGGFHE 69
Query: 745 VQPPNLEKKLESL--PSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQA-GVVP 575
Q N+E ++ M+ ++S+ QL AT +FRKLLS E +PPI+EVI GVV
Sbjct: 70 AQMNNMEMTSSAVITSDMIEMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 574 RFVEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQA 395
RFVEFL R++ LQFEAAW LTNIASG S TR+VI GAVPIF++LL+S +DV+EQA
Sbjct: 130 RFVEFLKRKENCTLQFEAAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 394 VWALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQF 218
VWALGN+AGDS CRD VL L PLL L++ +++M RNA W LSN CRGK P P F
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLLSKQNRITMTRNAVWALSNLCRGKNPPPDF 249
Query: 217 DQVKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPS 38
+V P L L L+ ND +VL DACWALSYLSDG NDKIQAVI+AGVC RLV+LL+H
Sbjct: 250 AKVSPCLSVLSWLLFVNDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHND 309
Query: 37 PAVLIPALRTVG 2
V+ PALR VG
Sbjct: 310 YKVVSPALRAVG 321
>sp|O15131|IMA5_HUMAN Importin subunit alpha-6 OS=Homo sapiens GN=KPNA5 PE=1
SV=1
Length = 536
Score = 272 bits (694), Expect = 4e-072
Identities = 156/305 (51%), Positives = 204/305 (66%), Gaps = 13/305 (4%)
Frame = -3
Query: 901 EVRRNRYKVAVDAEEGRRRREDNMVEIRK---SKREESLLKKRREGLQAQQFPASVQPPN 731
E+RR R + + +++RE+ + + R + +ES+L+ +Q ++V P
Sbjct: 23 EMRRRREEEGIQLR--KQKREEQLFKRRNVYLPRNDESMLE---SPIQDSDISSTVPIP- 76
Query: 730 LEKKLESLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQ-AGVVPRFVEFLV 554
++ MV ++S+ + QL AT +FRKLLS E +PPI++VIQ GVV RFV+FL
Sbjct: 77 --EEGVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLE 134
Query: 553 REDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNV 374
R + LQFEAAWALTNIASGT +T+VVI+ GAVPIF+KLL S +DV+EQAVWALGN+
Sbjct: 135 RNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNI 194
Query: 373 AGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPAL 197
AGD+ CRD VL+ L PLL L +L+ RNA W LSN CRGK P P F +V P L
Sbjct: 195 AGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCL 254
Query: 196 PALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPA 17
L RL+ S+D +VL D CWALSYLSDG NDKIQAVI++GVC RLV+LL+H V+ PA
Sbjct: 255 NVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPA 314
Query: 16 LRTVG 2
LR VG
Sbjct: 315 LRAVG 319
>sp|P52293|IMA2_MOUSE Importin subunit alpha-2 OS=Mus musculus GN=Kpna2 PE=1
SV=2
Length = 529
Score = 270 bits (688), Expect = 2e-071
Identities = 152/318 (47%), Positives = 200/318 (62%), Gaps = 17/318 (5%)
Frame = -3
Query: 928 MSLRPNARTEVRR-NRYK-VAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQF 755
MS NA R NR+K D+ E RRRR + VE+RK+K++E +LK+R F
Sbjct: 1 MSTNENANLPAARLNRFKNKGKDSTEMRRRRIEVNVELRKAKKDEQMLKRR----NVSSF 56
Query: 754 PASVQPPNLEKKLE------SLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVI 593
P P E + S+ +V G+ S+ QL+AT RKLLS E+ PPI+ +I
Sbjct: 57 PDDATSPLQENRNNQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNII 116
Query: 592 QAGVVPRFVEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSD 413
+AG++P+FV FL + D +QFE+AWALTNIASGTS+ T+ V+D GA+P F+ LLASP
Sbjct: 117 RAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHA 176
Query: 412 DVREQAVWALGNVAGDSPRCRDLVLSSGALMPLLAQLN----EHAKLSMLRNATWTLSNF 245
+ EQAVWALGN+AGD RDLV+ GA+ PLLA L LRN TWTLSN
Sbjct: 177 HISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNL 236
Query: 244 CRGK-PQPQFDQVKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCP 68
CR K P P D V+ LP L RL+H ND EVL D+CWA+SYL+DG N++I+ V++ GV P
Sbjct: 237 CRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVP 296
Query: 67 RLVQLLLHPSPAVLIPAL 14
+LV+LL ++ PAL
Sbjct: 297 QLVKLLGATELPIVTPAL 314
>sp|Q56R16|IMA5_RAT Importin subunit alpha-6 OS=Rattus norvegicus GN=Kpna5 PE=2
SV=1
Length = 536
Score = 268 bits (683), Expect = 7e-071
Identities = 157/304 (51%), Positives = 199/304 (65%), Gaps = 11/304 (3%)
Frame = -3
Query: 901 EVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQA--QQFPASVQPPNL 728
E+RR R EEG + R+ E +R SL + L++ Q S P
Sbjct: 23 EMRRRR------EEEGIQLRKQKREEQLFKRRNVSLPRNDDCMLESPIQDPDVSSTVPIP 76
Query: 727 EKKLESLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQ-AGVVPRFVEFLVR 551
E+ + + M+ ++S+ + QL AT +FRKLLS E +PPI++VIQ GVV RFV+FL R
Sbjct: 77 EEDMIT-ADMIQMIFSNNAEQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLER 135
Query: 550 EDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVA 371
+ LQFEAAWALTNIASGT +T+VVI+ GAVPIF++LL S +DV+EQAVWALGN+A
Sbjct: 136 NENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIRLLTSEHEDVQEQAVWALGNIA 195
Query: 370 GDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPALP 194
GD+ CRD VL+ L PLL L +L+ RNA W LSN CRGK P P F +V P L
Sbjct: 196 GDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLN 255
Query: 193 ALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPAL 14
L RL+ S+D +VL D CWALSYLSDG NDKIQ VI++GVC RLV+LL+H V+ PAL
Sbjct: 256 VLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQVVIDSGVCRRLVELLMHNDYKVVSPAL 315
Query: 13 RTVG 2
R VG
Sbjct: 316 RAVG 319
>sp|A2VE08|IMA1_BOVIN Importin subunit alpha-1 OS=Bos taurus GN=KPNA1 PE=2 SV=1
Length = 538
Score = 267 bits (682), Expect = 9e-071
Identities = 156/312 (50%), Positives = 202/312 (64%), Gaps = 12/312 (3%)
Frame = -3
Query: 925 SLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPAS 746
SL P+ E+RR R + + +++RE+ + + R E ++ E + +
Sbjct: 18 SLNPD---EMRRRREEEGLQLR--KQKREEQLFKRRNVATAE---EETEEEVMSDGGFHE 69
Query: 745 VQPPNLEKKLESL--PSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQA-GVVP 575
Q N+E + M+ ++S+ QL AT +FRKLLS E +PPI+EVI GVV
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 574 RFVEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQA 395
RFVEFL R++ LQFE+AW LTNIASG S TR+VI GAVPIF++LL+S +DV+EQA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 394 VWALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQF 218
VWALGN+AGDS CRD VL L PLL ++ +L+M RNA W LSN CRGK P P+F
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 217 DQVKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPS 38
+V P L L L+ +D +VL DACWALSYLSDG NDKIQAVI+AGVC RLV+LL+H
Sbjct: 250 AKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHND 309
Query: 37 PAVLIPALRTVG 2
V+ PALR VG
Sbjct: 310 YKVVSPALRAVG 321
>sp|P52171|IMA2_XENLA Importin subunit alpha-2 OS=Xenopus laevis GN=kpna2 PE=1
SV=2
Length = 523
Score = 267 bits (682), Expect = 9e-071
Identities = 138/297 (46%), Positives = 194/297 (65%), Gaps = 13/297 (4%)
Frame = -3
Query: 868 DAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPA-------SVQPPNLEKKLES 710
D E RRRR + VE+RK+K++E +LK+R + + S+Q P L S
Sbjct: 20 DTAELRRRRVEVSVELRKAKKDEQILKRRNVCFPEELILSPEKNAMQSIQVPQL-----S 74
Query: 709 LPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPRFVEFLVREDYPQLQ 530
L +V G+ S ++ +L +T RK+LS ER+PP+ ++I+AG++P+ VEFL + LQ
Sbjct: 75 LEEIVQGMNSGDNENELRSTQAARKMLSKERNPPLNDIIEAGLIPKLVEFLSYHNNSTLQ 134
Query: 529 FEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVAGDSPRCR 350
FEAAWALTNIASGTSD T+ V+D GA+P F+ L++SP + EQAVWALGN+AGD P R
Sbjct: 135 FEAAWALTNIASGTSDQTKSVVDGGAIPAFISLISSPHLHISEQAVWALGNIAGDGPLYR 194
Query: 349 DLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPALPALERLVH 173
D ++S + PLL +N L LRN TWTLSN CR K P P V LP L +L+
Sbjct: 195 DALISCNVIPPLLTLVNPQTPLGYLRNITWTLSNLCRNKNPYPPMSAVLQILPVLTQLML 254
Query: 172 SNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPALRTVG 2
D+++L+D CWA+SYL+DG+ND+I V++ G+ RL+QL+ P ++L P+LRTVG
Sbjct: 255 HEDKDILSDTCWAMSYLTDGSNDRIDVVVKTGLVERLIQLMYSPELSILTPSLRTVG 311
>sp|P52294|IMA1_HUMAN Importin subunit alpha-1 OS=Homo sapiens GN=KPNA1 PE=1
SV=2
Length = 538
Score = 267 bits (681), Expect = 1e-070
Identities = 156/312 (50%), Positives = 201/312 (64%), Gaps = 12/312 (3%)
Frame = -3
Query: 925 SLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPAS 746
SL P+ E+RR R + + +++RE+ + + R E ++ E + +
Sbjct: 18 SLNPD---EMRRRREEEGLQLR--KQKREEQLFKRRNVATAE---EETEEEVMSDGGFHE 69
Query: 745 VQPPNLEKKLESL--PSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQA-GVVP 575
Q N+E + M+ ++S QL AT +FRKLLS E +PPI+EVI GVV
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 574 RFVEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQA 395
RFVEFL R++ LQFE+AW LTNIASG S TR+VI GAVPIF++LL+S +DV+EQA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 394 VWALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQF 218
VWALGN+AGDS CRD VL L PLL ++ +L+M RNA W LSN CRGK P P+F
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 217 DQVKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPS 38
+V P L L L+ +D +VL DACWALSYLSDG NDKIQAVI+AGVC RLV+LL+H
Sbjct: 250 AKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHND 309
Query: 37 PAVLIPALRTVG 2
V+ PALR VG
Sbjct: 310 YKVVSPALRAVG 321
>sp|Q5R909|IMA1_PONAB Importin subunit alpha-1 OS=Pongo abelii GN=KPNA1 PE=2
SV=1
Length = 538
Score = 267 bits (681), Expect = 1e-070
Identities = 156/312 (50%), Positives = 201/312 (64%), Gaps = 12/312 (3%)
Frame = -3
Query: 925 SLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPAS 746
SL P+ E+RR R + + +++RE+ + + R E ++ E + +
Sbjct: 18 SLNPD---EMRRRREEEGLQLR--KQKREEQLFKRRNVATAE---EETEEEVMSDGGFHE 69
Query: 745 VQPPNLEKKLESL--PSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQA-GVVP 575
Q N+E + M+ ++S QL AT +FRKLLS E +PPI+EVI GVV
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 574 RFVEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQA 395
RFVEFL R++ LQFE+AW LTNIASG S TR+VI GAVPIF++LL+S +DV+EQA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 394 VWALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQF 218
VWALGN+AGDS CRD VL L PLL ++ +L+M RNA W LSN CRGK P P+F
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 217 DQVKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPS 38
+V P L L L+ +D +VL DACWALSYLSDG NDKIQAVI+AGVC RLV+LL+H
Sbjct: 250 AKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHND 309
Query: 37 PAVLIPALRTVG 2
V+ PALR VG
Sbjct: 310 YKVVSPALRAVG 321
>sp|P52292|IMA2_HUMAN Importin subunit alpha-2 OS=Homo sapiens GN=KPNA2 PE=1
SV=1
Length = 529
Score = 267 bits (681), Expect = 1e-070
Identities = 153/318 (48%), Positives = 201/318 (63%), Gaps = 17/318 (5%)
Frame = -3
Query: 928 MSLRPNARTEVRR-NRYK-VAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQF 755
MS NA T R +R+K D+ E RRRR + VE+RK+K+++ +LK+R F
Sbjct: 1 MSTNENANTPAARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRR----NVSSF 56
Query: 754 PASVQPPNLEKKLE------SLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVI 593
P P E + S+ +V G+ SS QL+AT RKLLS E+ PPI+ +I
Sbjct: 57 PDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNII 116
Query: 592 QAGVVPRFVEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSD 413
+AG++P+FV FL R D +QFE+AWALTNIASGTS+ T+ V+D GA+P F+ LLASP
Sbjct: 117 RAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHA 176
Query: 412 DVREQAVWALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSM----LRNATWTLSNF 245
+ EQAVWALGN+AGD RDLV+ GA+ PLLA L S+ LRN TWTLSN
Sbjct: 177 HISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
Query: 244 CRGK-PQPQFDQVKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCP 68
CR K P P D V+ LP L RL+H +D EVL D CWA+SYL+DG N++I V++ GV P
Sbjct: 237 CRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVP 296
Query: 67 RLVQLLLHPSPAVLIPAL 14
+LV+LL ++ PAL
Sbjct: 297 QLVKLLGASELPIVTPAL 314
>sp|P83953|IMA1_RAT Importin subunit alpha-1 OS=Rattus norvegicus GN=Kpna1 PE=2
SV=1
Length = 538
Score = 266 bits (679), Expect = 2e-070
Identities = 156/312 (50%), Positives = 201/312 (64%), Gaps = 12/312 (3%)
Frame = -3
Query: 925 SLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPAS 746
SL P+ E+RR R + + +++RE+ + + R E ++ E + +
Sbjct: 18 SLNPD---EMRRRREEEGLQLR--KQKREEQLFKRRNVATAE---EETEEEVMSDGGFHE 69
Query: 745 VQPPNLEKKLESL--PSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQA-GVVP 575
Q N+E + M ++S+ QL AT +FRKLLS E +PPI+EVI GVV
Sbjct: 70 AQINNMEMAPGGVITSDMTEMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVA 129
Query: 574 RFVEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQA 395
RFVEFL R++ LQFE+AW LTNIASG S TR+VI GAVPIF++LL+S +DV+EQA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 394 VWALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQF 218
VWALGN+AGDS CRD VL L PLL ++ +L+M RNA W LSN CRGK P P+F
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 217 DQVKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPS 38
+V P L L L+ +D +VL DACWALSYLSDG NDKIQAVI+AGVC RLV+LL+H
Sbjct: 250 AKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHND 309
Query: 37 PAVLIPALRTVG 2
V+ PALR VG
Sbjct: 310 YKVVSPALRAVG 321
>sp|Q60960|IMA1_MOUSE Importin subunit alpha-1 OS=Mus musculus GN=Kpna1 PE=1
SV=2
Length = 538
Score = 264 bits (673), Expect = 1e-069
Identities = 156/312 (50%), Positives = 201/312 (64%), Gaps = 12/312 (3%)
Frame = -3
Query: 925 SLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPAS 746
SL P+ E+RR R + + +++RE+ + + R E ++ E + +
Sbjct: 18 SLNPD---EMRRRREEEGLQLR--KQKREEQLFKRRNVATAE---EETEEEVMSDGGFHE 69
Query: 745 VQPPNLEKKLESL--PSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQA-GVVP 575
Q N+E + M ++S+ QL AT +FRKLLS E +PPI+EVI GVV
Sbjct: 70 AQINNMEMAPGGVITSDMTDMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVA 129
Query: 574 RFVEFLVREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQA 395
RFVEFL R++ LQFE+AW LTNIASG S TR VI GAVPIF++LL+S +DV+EQA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRNVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 394 VWALGNVAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQF 218
VWALGN+AGDS CRD VL+ L PLL ++ +L+M RNA W LSN CRGK P P+F
Sbjct: 190 VWALGNIAGDSTMCRDYVLNCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 217 DQVKPALPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPS 38
+V P L L L+ +D +VL DACWALSYLSDG NDKIQAVI+AGVC RLV+LL+H
Sbjct: 250 AKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHND 309
Query: 37 PAVLIPALRTVG 2
V+ PALR VG
Sbjct: 310 YKVVSPALRAVG 321
>sp|O35344|IMA3_MOUSE Importin subunit alpha-3 OS=Mus musculus GN=Kpna3 PE=2
SV=1
Length = 521
Score = 259 bits (661), Expect = 3e-068
Identities = 140/294 (47%), Positives = 188/294 (63%), Gaps = 10/294 (3%)
Frame = -3
Query: 868 DAEEGRRRREDNMVEIRKSKREESLLKKR----REGLQAQQFPASVQPPNLEKKLESLPS 701
D E RR R + VE+RK+KR+E LLKKR E L+ A + N+ +L +
Sbjct: 21 DVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNV-----TLEA 75
Query: 700 MVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPRFVEFLVREDYPQLQFEA 521
++ S +QL A RKLLS +R+PPI+++I++G++P V+ L R+D P LQFEA
Sbjct: 76 ILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEA 135
Query: 520 AWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVAGDSPRCRDLV 341
AWALTNIASGTS T+ V+ AVP+F++LL SP +V EQAVWALGN+ GD P+CRD V
Sbjct: 136 AWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYV 195
Query: 340 LSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPALPALERLVHSND 164
+S G + PLL+ +N ++ LRN TW + N CR K P P + V+ LPAL L++ D
Sbjct: 196 ISLGVVKPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTD 255
Query: 163 EEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPALRTVG 2
+L D WALSYL+DG N++IQ VI++GV P LV LL H V ALR VG
Sbjct: 256 INILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
>sp|P52295|IMA_DROME Importin subunit alpha OS=Drosophila melanogaster GN=Pen
PE=1 SV=2
Length = 522
Score = 258 bits (659), Expect = 4e-068
Identities = 139/306 (45%), Positives = 196/306 (64%), Gaps = 5/306 (1%)
Frame = -3
Query: 910 ARTEVRRNRYKV-AVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPASVQPP 734
A + R+ YK +++ ++ R RR + +E+RKSK+E+ + K+R + + + ++
Sbjct: 4 ADSNSRQGSYKANSINTQDSRMRRHEVTIELRKSKKEDQMFKRR--NINDEDLTSPLKEL 61
Query: 733 NLEKKLE-SLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPRFVEFL 557
N + ++ S+ +VA + S + Q RK+LS ER+PPI+ +I G+VP + FL
Sbjct: 62 NGQSPVQLSVDEIVAAMNSEDQERQFLGMQSARKMLSRERNPPIDLMIGHGIVPICIRFL 121
Query: 556 VREDYPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGN 377
+ LQFEAAWALTNIASGTSD TR VI+H AVP FV LL S S ++ EQAVWALGN
Sbjct: 122 QNTNNSMLQFEAAWALTNIASGTSDQTRCVIEHNAVPHFVALLQSKSMNLAEQAVWALGN 181
Query: 376 VAGDSPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPA 200
+AGD RD+V+ + +L +N LS LRN W +SN CR K P P FDQVK
Sbjct: 182 IAGDGAAARDIVIHHNVIDGILPLINNETPLSFLRNIVWLMSNLCRNKNPSPPFDQVKRL 241
Query: 199 LPALERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIP 20
LP L +L+ S D +VL DACWALSY++D N KIQAV+++ PRLV+LL P++++P
Sbjct: 242 LPVLSQLLLSQDIQVLADACWALSYVTDDDNTKIQAVVDSDAVPRLVKLLQMDEPSIIVP 301
Query: 19 ALRTVG 2
ALR+VG
Sbjct: 302 ALRSVG 307
>sp|O00505|IMA3_HUMAN Importin subunit alpha-3 OS=Homo sapiens GN=KPNA3 PE=1
SV=2
Length = 521
Score = 258 bits (657), Expect = 7e-068
Identities = 139/294 (47%), Positives = 188/294 (63%), Gaps = 10/294 (3%)
Frame = -3
Query: 868 DAEEGRRRREDNMVEIRKSKREESLLKKR----REGLQAQQFPASVQPPNLEKKLESLPS 701
D E RR R + VE+RK+KR+E LLKKR E L+ A + N+ +L +
Sbjct: 21 DVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNV-----TLEA 75
Query: 700 MVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPRFVEFLVREDYPQLQFEA 521
++ S +QL A RKLLS +R+PPI+++I++G++P V+ L R+D P LQFEA
Sbjct: 76 ILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEA 135
Query: 520 AWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVAGDSPRCRDLV 341
AWALTNIASGTS T+ V+ AVP+F++LL SP +V EQAVWALGN+ GD P+CRD V
Sbjct: 136 AWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYV 195
Query: 340 LSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPALPALERLVHSND 164
+S G + PLL+ ++ ++ LRN TW + N CR K P P + V+ LPAL L++ D
Sbjct: 196 ISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTD 255
Query: 163 EEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPALRTVG 2
+L D WALSYL+DG N++IQ VI++GV P LV LL H V ALR VG
Sbjct: 256 INILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
>sp|A9QM74|IMA8_HUMAN Importin subunit alpha-8 OS=Homo sapiens GN=KPNA7 PE=2
SV=1
Length = 516
Score = 256 bits (653), Expect = 2e-067
Identities = 145/302 (48%), Positives = 194/302 (64%), Gaps = 3/302 (0%)
Frame = -3
Query: 901 EVRRNRYKV-AVDAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPASVQPPNLE 725
E RR ++K D R++R +E+RK+K++E LK+R P+ +
Sbjct: 8 EERRRKFKYRGKDVSLRRQQRMAVSLELRKAKKDEQTLKRRNITSFCPDTPSEKTAKGVA 67
Query: 724 KKLESLPSMVAGVWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPRFVEFLVRED 545
L +L ++ GV SS+ L +AT RK+LS E++PP++ VI+AG++PR VEFL
Sbjct: 68 VSL-TLGEIIKGVNSSDPVLCFQATQTARKMLSQEKNPPLKLVIEAGLIPRMVEFLKSSL 126
Query: 544 YPQLQFEAAWALTNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVAGD 365
YP LQFEAAWALTNIASGTS+ TR V++ GA+ ++LL+S + V EQAVWALGN+AGD
Sbjct: 127 YPCLQFEAAWALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAVCEQAVWALGNIAGD 186
Query: 364 SPRCRDLVLSSGALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPALPAL 188
P RD V++S A+ LLA ++ ++ LRN TWTLSN CR K P P VK LPAL
Sbjct: 187 GPEFRDNVITSNAIPHLLALISPTLPITFLRNITWTLSNLCRNKNPYPCDTAVKQILPAL 246
Query: 187 ERLVHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPALRT 8
L+ D EVL+DACWALSYL+DG+N +I V+ GV PRLV L+ VL P+LRT
Sbjct: 247 LHLLQHQDSEVLSDACWALSYLTDGSNKRIGQVVNTGVLPRLVVLMTSSELNVLTPSLRT 306
Query: 7 VG 2
VG
Sbjct: 307 VG 308
>sp|O35343|IMA4_MOUSE Importin subunit alpha-4 OS=Mus musculus GN=Kpna4 PE=2
SV=1
Length = 521
Score = 255 bits (651), Expect = 4e-067
Identities = 137/290 (47%), Positives = 186/290 (64%), Gaps = 2/290 (0%)
Frame = -3
Query: 868 DAEEGRRRREDNMVEIRKSKREESLLKKRREGLQAQQFPASVQPPNLEKKLESLPSMVAG 689
D E RR+R + +VE+RK+KR+E LL KRR Q S + + SL ++V
Sbjct: 21 DLETMRRQRNEVVVELRKNKRDEHLL-KRRNVPQEDICEDSDIDGDYRVQNTSLEAIVQN 79
Query: 688 VWSSESALQLEATTQFRKLLSIERSPPIEEVIQAGVVPRFVEFLVREDYPQLQFEAAWAL 509
S +QL A RKLLS +R+PPI+++I++G++P V L R+D P LQFEAAWAL
Sbjct: 80 ASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWAL 139
Query: 508 TNIASGTSDNTRVVIDHGAVPIFVKLLASPSDDVREQAVWALGNVAGDSPRCRDLVLSSG 329
TNIASGTS+ T+ V+ AVP+F++LL SP +V EQAVWALGN+ GD P+CRD V+S G
Sbjct: 140 TNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLG 199
Query: 328 ALMPLLAQLNEHAKLSMLRNATWTLSNFCRGK-PQPQFDQVKPALPALERLVHSNDEEVL 152
+ PLL+ ++ ++ LRN TW + N CR K P P + ++ LPAL L+H D +L
Sbjct: 200 VVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNIL 259
Query: 151 TDACWALSYLSDGTNDKIQAVIEAGVCPRLVQLLLHPSPAVLIPALRTVG 2
D WALSYL+D N++IQ VI++G+ P LV LL H V ALR VG
Sbjct: 260 VDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVG 309
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,055,803,260
Number of Sequences: 462764
Number of Extensions: 3055803260
Number of Successful Extensions: 28798457
Number of sequences better than 0.0: 0
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