BLASTX 7.6.2 Query= RU01690 /QuerySize=1591 (1590 letters) Database: UniProt/Swiss-Prot; 462,764 sequences; 163,773,382 total letters Score E Sequences producing significant alignments: (bits) Value sp|P46466|PRS4_ORYSJ 26S protease regulatory subunit 4 homolog O... 771 4e-222 sp|P48601|PRS4_DROME 26S protease regulatory subunit 4 OS=Drosop... 658 4e-188 sp|P62191|PRS4_HUMAN 26S protease regulatory subunit 4 OS=Homo s... 650 1e-185 sp|P62192|PRS4_MOUSE 26S protease regulatory subunit 4 OS=Mus mu... 650 1e-185 sp|P62193|PRS4_RAT 26S protease regulatory subunit 4 OS=Rattus n... 650 1e-185 sp|Q90732|PRS4_CHICK 26S protease regulatory subunit 4 OS=Gallus... 647 7e-185 sp|O16368|PRS4_CAEEL Probable 26S protease regulatory subunit 4 ... 634 5e-181 sp|Q55BV5|PRS4_DICDI 26S protease regulatory subunit 4 homolog O... 609 3e-173 sp|P36612|PRS4_SCHPO 26S protease regulatory subunit 4 homolog O... 587 9e-167 sp|P40327|PRS4_YEAST 26S protease regulatory subunit 4 homolog O... 577 7e-164 sp|P46507|PRS6B_MANSE 26S protease regulatory subunit 6B OS=Mand... 387 1e-106 sp|P46502|PRS6B_CAEEL Probable 26S protease regulatory subunit 6... 385 5e-106 sp|Q9SEI4|PRS6B_ARATH 26S protease regulatory subunit 6B homolog... 380 2e-104 sp|O28303|PSMR_ARCFU Proteasome-activating nucleotidase OS=Archa... 380 2e-104 sp|Q3T030|PRS6B_BOVIN 26S protease regulatory subunit 6B OS=Bos ... 379 4e-104 sp|P43686|PRS6B_HUMAN 26S protease regulatory subunit 6B OS=Homo... 379 4e-104 sp|Q4R7L3|PRS6B_MACFA 26S protease regulatory subunit 6B OS=Maca... 379 4e-104 sp|Q63570|PRS6B_RAT 26S protease regulatory subunit 6B OS=Rattus... 379 4e-104 sp|P54778|PRS6B_SOLTU 26S protease regulatory subunit 6B homolog... 372 4e-102 sp|P54775|PRS6B_MOUSE 26S protease regulatory subunit 6B OS=Mus ... 369 4e-101 sp|P34123|PRS6B_DICDI 26S protease regulatory subunit 6B homolog... 368 6e-101 sp|Q8SQI9|PRS6B_ENCCU 26S protease regulatory subunit 6B homolog... 361 8e-099 sp|Q58576|PSMR_METJA Proteasome-activating nucleotidase OS=Metha... 359 3e-098 sp|O26824|PSMR_METTH Proteasome-activating nucleotidase OS=Metha... 359 3e-098 sp|Q8TX03|PSMR_METKA Proteasome-activating nucleotidase OS=Metha... 356 2e-097 sp|A3CV35|PSMR_METMJ Proteasome-activating nucleotidase OS=Metha... 350 2e-095 sp|Q0W257|PSMR_UNCMA Proteasome-activating nucleotidase OS=Uncul... 343 3e-093 sp|A7I8B8|PSMR_METB6 Proteasome-activating nucleotidase OS=Metha... 340 2e-092 sp|O18413|PRS8_DROME 26S protease regulatory subunit 8 OS=Drosop... 335 8e-091 sp|Q2FQ56|PSMR_METHJ Proteasome-activating nucleotidase OS=Metha... 335 8e-091 >sp|P46466|PRS4_ORYSJ 26S protease regulatory subunit 4 homolog OS=Oryza sativa subsp. japonica GN=TBP2 PE=2 SV=2 Length = 448 Score = 771 bits (1989), Expect = 4e-222 Identities = 396/448 (88%), Positives = 412/448 (91%), Gaps = 2/448 (0%) Frame = +2 Query: 59 MGQGTPGGLNRQ-GLPGDRKPDGN-DXXXXXXXXXXXXXRVGRKQRKQKGPEAAARLPTV 232 MGQGTPGG+ +Q G PGDRKP G+ D RVGRKQRKQKGPEAAARLP V Sbjct: 1 MGQGTPGGMGKQGGAPGDRKPGGDGDKKDRKFEPPAAPSRVGRKQRKQKGPEAAARLPNV 60 Query: 233 TPLTKCKLRLLKLERIKDYLLMEEEFVTNQERLKPQEEKAEEDRSKVDDLRGSPMSVGNL 412 PL+KC+LRLLKLER+KDYLLMEEEFV QERL+P E+K EEDRSKVDDLRG+PMSVG+L Sbjct: 61 APLSKCRLRLLKLERVKDYLLMEEEFVAAQERLRPTEDKTEEDRSKVDDLRGTPMSVGSL 120 Query: 413 EELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVS 592 EE+IDE+HAIVSSSVGPEYYVGILSFVDKDQLEPGC+ILMHNKVLSVVG+LQDEVDPMVS Sbjct: 121 EEIIDESHAIVSSSVGPEYYVGILSFVDKDQLEPGCSILMHNKVLSVVGILQDEVDPMVS 180 Query: 593 VMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGK 772 VMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGK Sbjct: 181 VMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGK 240 Query: 773 TLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGT 952 TLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVAD+LSPSIVFIDEIDAVGT Sbjct: 241 TLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADELSPSIVFIDEIDAVGT 300 Query: 953 KRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIE 1132 KRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIE Sbjct: 301 KRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIE 360 Query: 1133 FPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRM 1312 FPLPDIKTRRRIFQIHTS+MTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRM Sbjct: 361 FPLPDIKTRRRIFQIHTSKMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRM 420 Query: 1313 KVTHADFXXXXXXXXXXXXEGVPEGLYM 1396 KVTHADF EGVPEGLYM Sbjct: 421 KVTHADFKKAKEKVMFKKKEGVPEGLYM 448 >sp|P48601|PRS4_DROME 26S protease regulatory subunit 4 OS=Drosophila melanogaster GN=Pros26.4 PE=1 SV=2 Length = 439 Score = 658 bits (1696), Expect = 4e-188 Identities = 324/409 (79%), Positives = 372/409 (90%) Frame = +2 Query: 170 RVGRKQRKQKGPEAAARLPTVTPLTKCKLRLLKLERIKDYLLMEEEFVTNQERLKPQEEK 349 RVG+K+R+ KGP+AA +LP VTP T+C+L+LLKLERIKDYL+ME+EF+ NQERLKPQ+EK Sbjct: 31 RVGKKKRRAKGPDAAMKLPQVTPHTRCRLKLLKLERIKDYLMMEDEFIRNQERLKPQDEK 90 Query: 350 AEEDRSKVDDLRGSPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAIL 529 EE+RSKVDDLRG+PMSVGNLEE+ID+NHAIVS+SVG E+YV ILSFVDKDQLEPGC++L Sbjct: 91 NEEERSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVL 150 Query: 530 MHNKVLSVVGLLQDEVDPMVSVMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELY 709 +++KV +VVG+L D+ DPMV+VMK+EKAP E+YADIGGLD QIQEIKE+VELPLTHPE Y Sbjct: 151 LNHKVHAVVGVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYY 210 Query: 710 EDIGIRPPKGVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELF 889 E++GI+PPKGVILYG PGTGKTLLAKAVAN TSATFLRVVGSELIQKYLGDGPKLVRELF Sbjct: 211 EEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELF 270 Query: 890 RVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILAT 1069 RVA++ +PSIVFIDEIDAVGTKRYD++SGGEREIQRTMLELLNQLDGFDSRGDVKVI+AT Sbjct: 271 RVAEEHAPSIVFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMAT 330 Query: 1070 NRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFS 1249 NRIE+LDPAL+RPGRIDRKIEFPLPD KT+RRIF IHTSRMTLA+DVNL E +M KD+ S Sbjct: 331 NRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAEDVNLSELIMAKDDLS 390 Query: 1250 GADIKAICTEAGLLALRERRMKVTHADFXXXXXXXXXXXXEGVPEGLYM 1396 GADIKAICTEAGL+ALRERRMKVT+ DF EG PEGLY+ Sbjct: 391 GADIKAICTEAGLMALRERRMKVTNEDFKKSKESVLYRKKEGTPEGLYL 439 >sp|P62191|PRS4_HUMAN 26S protease regulatory subunit 4 OS=Homo sapiens GN=PSMC1 PE=1 SV=1 Length = 440 Score = 650 bits (1675), Expect = 1e-185 Identities = 319/409 (77%), Positives = 371/409 (90%) Frame = +2 Query: 170 RVGRKQRKQKGPEAAARLPTVTPLTKCKLRLLKLERIKDYLLMEEEFVTNQERLKPQEEK 349 RVG+K++K KGP+AA++LP VTP T+C+L+LLKLERIKDYLLMEEEF+ NQE++KP EEK Sbjct: 32 RVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEK 91 Query: 350 AEEDRSKVDDLRGSPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAIL 529 EE+RSKVDDLRG+PMSVG LEE+ID+NHAIVS+SVG E+YV ILSFVDKD LEPGC++L Sbjct: 92 QEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVL 151 Query: 530 MHNKVLSVVGLLQDEVDPMVSVMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELY 709 +++KV +V+G+L D+ DP+V+VMKVEKAP E+YADIGGLD QIQEIKE+VELPLTHPE Y Sbjct: 152 LNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYY 211 Query: 710 EDIGIRPPKGVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELF 889 E++GI+PPKGVILYG PGTGKTLLAKAVAN TSATFLRVVGSELIQKYLGDGPKLVRELF Sbjct: 212 EEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELF 271 Query: 890 RVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILAT 1069 RVA++ +PSIVFIDEIDA+GTKRYD++SGGEREIQRTMLELLNQLDGFDSRGDVKVI+AT Sbjct: 272 RVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMAT 331 Query: 1070 NRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFS 1249 NRIE+LDPAL+RPGRIDRKIEFPLPD KT++RIFQIHTSRMTLADDV L++ +M KD+ S Sbjct: 332 NRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLS 391 Query: 1250 GADIKAICTEAGLLALRERRMKVTHADFXXXXXXXXXXXXEGVPEGLYM 1396 GADIKAICTEAGL+ALRERRMKVT+ DF EG PEGLY+ Sbjct: 392 GADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL 440 >sp|P62192|PRS4_MOUSE 26S protease regulatory subunit 4 OS=Mus musculus GN=Psmc1 PE=1 SV=1 Length = 440 Score = 650 bits (1675), Expect = 1e-185 Identities = 319/409 (77%), Positives = 371/409 (90%) Frame = +2 Query: 170 RVGRKQRKQKGPEAAARLPTVTPLTKCKLRLLKLERIKDYLLMEEEFVTNQERLKPQEEK 349 RVG+K++K KGP+AA++LP VTP T+C+L+LLKLERIKDYLLMEEEF+ NQE++KP EEK Sbjct: 32 RVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEK 91 Query: 350 AEEDRSKVDDLRGSPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAIL 529 EE+RSKVDDLRG+PMSVG LEE+ID+NHAIVS+SVG E+YV ILSFVDKD LEPGC++L Sbjct: 92 QEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVL 151 Query: 530 MHNKVLSVVGLLQDEVDPMVSVMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELY 709 +++KV +V+G+L D+ DP+V+VMKVEKAP E+YADIGGLD QIQEIKE+VELPLTHPE Y Sbjct: 152 LNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYY 211 Query: 710 EDIGIRPPKGVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELF 889 E++GI+PPKGVILYG PGTGKTLLAKAVAN TSATFLRVVGSELIQKYLGDGPKLVRELF Sbjct: 212 EEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELF 271 Query: 890 RVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILAT 1069 RVA++ +PSIVFIDEIDA+GTKRYD++SGGEREIQRTMLELLNQLDGFDSRGDVKVI+AT Sbjct: 272 RVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMAT 331 Query: 1070 NRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFS 1249 NRIE+LDPAL+RPGRIDRKIEFPLPD KT++RIFQIHTSRMTLADDV L++ +M KD+ S Sbjct: 332 NRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLS 391 Query: 1250 GADIKAICTEAGLLALRERRMKVTHADFXXXXXXXXXXXXEGVPEGLYM 1396 GADIKAICTEAGL+ALRERRMKVT+ DF EG PEGLY+ Sbjct: 392 GADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL 440 >sp|P62193|PRS4_RAT 26S protease regulatory subunit 4 OS=Rattus norvegicus GN=Psmc1 PE=2 SV=1 Length = 440 Score = 650 bits (1675), Expect = 1e-185 Identities = 319/409 (77%), Positives = 371/409 (90%) Frame = +2 Query: 170 RVGRKQRKQKGPEAAARLPTVTPLTKCKLRLLKLERIKDYLLMEEEFVTNQERLKPQEEK 349 RVG+K++K KGP+AA++LP VTP T+C+L+LLKLERIKDYLLMEEEF+ NQE++KP EEK Sbjct: 32 RVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEK 91 Query: 350 AEEDRSKVDDLRGSPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAIL 529 EE+RSKVDDLRG+PMSVG LEE+ID+NHAIVS+SVG E+YV ILSFVDKD LEPGC++L Sbjct: 92 QEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVL 151 Query: 530 MHNKVLSVVGLLQDEVDPMVSVMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELY 709 +++KV +V+G+L D+ DP+V+VMKVEKAP E+YADIGGLD QIQEIKE+VELPLTHPE Y Sbjct: 152 LNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYY 211 Query: 710 EDIGIRPPKGVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELF 889 E++GI+PPKGVILYG PGTGKTLLAKAVAN TSATFLRVVGSELIQKYLGDGPKLVRELF Sbjct: 212 EEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELF 271 Query: 890 RVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILAT 1069 RVA++ +PSIVFIDEIDA+GTKRYD++SGGEREIQRTMLELLNQLDGFDSRGDVKVI+AT Sbjct: 272 RVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMAT 331 Query: 1070 NRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFS 1249 NRIE+LDPAL+RPGRIDRKIEFPLPD KT++RIFQIHTSRMTLADDV L++ +M KD+ S Sbjct: 332 NRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLS 391 Query: 1250 GADIKAICTEAGLLALRERRMKVTHADFXXXXXXXXXXXXEGVPEGLYM 1396 GADIKAICTEAGL+ALRERRMKVT+ DF EG PEGLY+ Sbjct: 392 GADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL 440 >sp|Q90732|PRS4_CHICK 26S protease regulatory subunit 4 OS=Gallus gallus GN=PSMC1 PE=2 SV=1 Length = 440 Score = 647 bits (1668), Expect = 7e-185 Identities = 318/409 (77%), Positives = 369/409 (90%) Frame = +2 Query: 170 RVGRKQRKQKGPEAAARLPTVTPLTKCKLRLLKLERIKDYLLMEEEFVTNQERLKPQEEK 349 RVG+K++K KGP+AA++ P VTP T+C+L+LLKLERIKDYLLMEEEF+ NQE++KP EEK Sbjct: 32 RVGKKKKKTKGPDAASKPPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEK 91 Query: 350 AEEDRSKVDDLRGSPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAIL 529 EE+RSKVDDLRG+PMSVG LEE+ID+NHAIVS+SVG E+YV ILSFVDKD LEPGC++L Sbjct: 92 QEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVL 151 Query: 530 MHNKVLSVVGLLQDEVDPMVSVMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELY 709 +++KV +V+G+L D+ DP+V+VMK+EKAP E+YADIGGLD QIQEIKE+VELPLTHPE Y Sbjct: 152 LNHKVHAVIGVLMDDTDPLVTVMKLEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYY 211 Query: 710 EDIGIRPPKGVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELF 889 E++GI+PPKGVILYG PGTGKTLLAKAVAN TSATFLRVVGSELIQKYLGDGPKLVRELF Sbjct: 212 EEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELF 271 Query: 890 RVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILAT 1069 RVA++ PSIVFIDEIDA+GTKRYD++SGGEREIQRTMLELLNQLDGFDSRGDVKVI+AT Sbjct: 272 RVAEEHGPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMAT 331 Query: 1070 NRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFS 1249 NRIE+LDPAL+RPGRIDRKIEFPLPD KT++RIFQIHTSRMTLADDV L+E +M KD+ S Sbjct: 332 NRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDELIMAKDDLS 391 Query: 1250 GADIKAICTEAGLLALRERRMKVTHADFXXXXXXXXXXXXEGVPEGLYM 1396 GADIKAICTEAGL+ALRERRMKVT+ DF EG PEGLY+ Sbjct: 392 GADIKAICTEAGLMALRERRMKVTNEDFKKSKENFLYKKTEGTPEGLYL 440 >sp|O16368|PRS4_CAEEL Probable 26S protease regulatory subunit 4 OS=Caenorhabditis elegans GN=rpt-2 PE=2 SV=1 Length = 443 Score = 634 bits (1635), Expect = 5e-181 Identities = 310/409 (75%), Positives = 366/409 (89%) Frame = +2 Query: 170 RVGRKQRKQKGPEAAARLPTVTPLTKCKLRLLKLERIKDYLLMEEEFVTNQERLKPQEEK 349 R+G+K++ KGP+AA++LP VTP +C+L+LLK ERIKDYLLME+EF+ NQERLKPQEE+ Sbjct: 35 RIGKKKKGSKGPDAASKLPAVTPHARCRLKLLKSERIKDYLLMEQEFIQNQERLKPQEER 94 Query: 350 AEEDRSKVDDLRGSPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAIL 529 EE+R+KVD+LRG+PM+VG+LEE+ID+ HAIVS++VG E+YV I+SFVDK+QLEPGC++L Sbjct: 95 QEEERAKVDELRGTPMAVGSLEEIIDDQHAIVSTNVGSEHYVNIMSFVDKEQLEPGCSVL 154 Query: 530 MHNKVLSVVGLLQDEVDPMVSVMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELY 709 +++K +V+G+L D+ DPMVSVMK+EKAP E+YAD+GGLD QIQEIKEAVELPLTHPE Y Sbjct: 155 LNHKNHAVIGVLSDDTDPMVSVMKLEKAPQETYADVGGLDQQIQEIKEAVELPLTHPEYY 214 Query: 710 EDIGIRPPKGVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELF 889 E++GIRPPKGVILYG PGTGKTLLAKAVAN TSATFLR+VGSELIQKYLGDGPK+VRELF Sbjct: 215 EEMGIRPPKGVILYGCPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPKMVRELF 274 Query: 890 RVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILAT 1069 RVA++ +PSIVFIDEIDAVGTKRYD++SGGEREIQRTMLELLNQLDGFDSRGDVKV++AT Sbjct: 275 RVAEENAPSIVFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVLMAT 334 Query: 1070 NRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFS 1249 NRIESLDPAL+RPGRIDRKIEFPLPD KT+RRIFQIHTSRMTL +VNLEEF+ KDE S Sbjct: 335 NRIESLDPALIRPGRIDRKIEFPLPDEKTKRRIFQIHTSRMTLGKEVNLEEFITAKDELS 394 Query: 1250 GADIKAICTEAGLLALRERRMKVTHADFXXXXXXXXXXXXEGVPEGLYM 1396 GADIKA+CTEAGLLALRERRM+VT DF EG PE LY+ Sbjct: 395 GADIKAMCTEAGLLALRERRMRVTMEDFQKSKENVLYRKKEGAPEELYL 443 >sp|Q55BV5|PRS4_DICDI 26S protease regulatory subunit 4 homolog OS=Dictyostelium discoideum GN=psmC1 PE=1 SV=1 Length = 439 Score = 609 bits (1568), Expect = 3e-173 Identities = 299/408 (73%), Positives = 356/408 (87%), Gaps = 3/408 (0%) Frame = +2 Query: 182 KQRKQKGPEAAARLPTVTPLTKCKLRLLKLERIKDYLLMEEEFVTNQERLKP---QEEKA 352 K++K++G E + +LP +TP +KCKL+ LKLERIKDYLLME+EF+ N + +P + K Sbjct: 32 KKKKRRGAETSTKLPVITPHSKCKLKQLKLERIKDYLLMEQEFLQNYDLNQPKVDENSKE 91 Query: 353 EEDRSKVDDLRGSPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAILM 532 + D +++LRG P++VGNLEE+ID+NHAIVSS+VGPE+YV I+SFVDK +L G +L+ Sbjct: 92 QADEKIIEELRGDPLTVGNLEEIIDDNHAIVSSTVGPEHYVRIMSFVDKSKLYLGATVLL 151 Query: 533 HNKVLSVVGLLQDEVDPMVSVMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELYE 712 +NK LSVVG++ EVDPMV+VMKVEKAP ESY+DIGGL+AQ+QE+KEA+ELPLTHPELYE Sbjct: 152 NNKTLSVVGVIDGEVDPMVNVMKVEKAPTESYSDIGGLEAQVQEMKEAIELPLTHPELYE 211 Query: 713 DIGIRPPKGVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELFR 892 +IGI+PPKGVILYGEPGTGKTLLAKAVAN TSATFLRVVGSELIQKYLGDGPKLVRELFR Sbjct: 212 EIGIKPPKGVILYGEPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFR 271 Query: 893 VADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILATN 1072 VAD+ +PSIVFIDEIDAVGTKRYD+ SGGEREIQRTMLELLNQLDGFD+R DVKVI+ATN Sbjct: 272 VADECAPSIVFIDEIDAVGTKRYDSQSGGEREIQRTMLELLNQLDGFDARTDVKVIMATN 331 Query: 1073 RIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSG 1252 RIE+LDPAL+RPGRIDRKIEFPLPDIKT+R+IF+IHT++M L++DVNLEEFVM+KD+ SG Sbjct: 332 RIETLDPALIRPGRIDRKIEFPLPDIKTKRKIFEIHTAKMNLSEDVNLEEFVMSKDDLSG 391 Query: 1253 ADIKAICTEAGLLALRERRMKVTHADFXXXXXXXXXXXXEGVPEGLYM 1396 ADIKAICTE+GLLALRERRM+VTH DF G PEGLYM Sbjct: 392 ADIKAICTESGLLALRERRMRVTHTDFKKAKEKVLYRKTAGAPEGLYM 439 >sp|P36612|PRS4_SCHPO 26S protease regulatory subunit 4 homolog OS=Schizosaccharomyces pombe GN=mts2 PE=2 SV=1 Length = 448 Score = 587 bits (1512), Expect = 9e-167 Identities = 299/447 (66%), Positives = 361/447 (80%), Gaps = 7/447 (1%) Frame = +2 Query: 59 MGQGTPGGLNR--QGLPGDRKPDGNDXXXXXXXXXXXXXRVGRKQRK-QKGPEAAARLPT 229 MGQ G + G GD K D R GR+++K Q GP+A+A+LPT Sbjct: 1 MGQAQSGNFSNFGDGANGDNKKD--QKKDKPKYEPPVPTRTGRRKKKAQSGPDASAKLPT 58 Query: 230 VTPLTKCKLRLLKLERIKDYLLMEEEFVTNQERLKPQEEKAEEDRSKVDDLRGSPMSVGN 409 V P T+C+LRLLK++RI D+LLMEEE+V NQERLKPQ+E+ +E+R++VD++RG+PMSVG Sbjct: 59 VIPTTRCRLRLLKMQRIHDHLLMEEEYVQNQERLKPQDERTQEERNRVDEIRGTPMSVGT 118 Query: 410 LEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMV 589 LEE+ID++HAIVS++ GPEYYV I+SFVDKD LEPGC++L+H+K +S+VGLL D+ DPM+ Sbjct: 119 LEEIIDDDHAIVSTA-GPEYYVSIMSFVDKDMLEPGCSVLLHHKAMSIVGLLLDDTDPMI 177 Query: 590 SVMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTG 769 +VMK++KAP ESYADIGGL++QIQEIKEAVELPLTHPELYE++GI+PPKGVILYG PGTG Sbjct: 178 NVMKLDKAPTESYADIGGLESQIQEIKEAVELPLTHPELYEEMGIKPPKGVILYGAPGTG 237 Query: 770 KTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVG 949 KTLLAKAVAN TSATFLRVVGSELIQKYLGDGP+LVR+LF A++ SPSIVFIDEIDA+G Sbjct: 238 KTLLAKAVANQTSATFLRVVGSELIQKYLGDGPRLVRQLFNAAEEHSPSIVFIDEIDAIG 297 Query: 950 TKRYDAHSGGEREIQRTMLELLNQLDGFD-SRGDVKVILATNRIESLDPALLRPGRIDRK 1126 TKRYDA SG EREIQRTMLELLNQLDGFD S+ D+KVI+ATNRI LDPAL+RPGRIDRK Sbjct: 298 TKRYDAQSGAEREIQRTMLELLNQLDGFDTSQRDIKVIMATNRISDLDPALIRPGRIDRK 357 Query: 1127 IEFPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRER 1306 I F PD T+R+IF IHTS+M L +DVNLEE + KD+ SGA+IKAI +EAGLLALRER Sbjct: 358 ILFENPDEATKRKIFTIHTSKMNLGEDVNLEELIQCKDDLSGAEIKAIVSEAGLLALRER 417 Query: 1307 RMKVTHADFXXXXXXXXXXXXEGVPEG 1387 RM+V DF EG P G Sbjct: 418 RMRVVMDDFRQAREKVLKTKDEGGPAG 444 >sp|P40327|PRS4_YEAST 26S protease regulatory subunit 4 homolog OS=Saccharomyces cerevisiae GN=RPT2 PE=1 SV=3 Length = 437 Score = 577 bits (1487), Expect = 7e-164 Identities = 280/409 (68%), Positives = 352/409 (86%), Gaps = 1/409 (0%) Frame = +2 Query: 170 RVGRKQRKQKGPEAAARLPTVTPLTKCKLRLLKLERIKDYLLMEEEFVTNQERLKPQEEK 349 + GRK+RK GP A +LP + P T+CKL+LL++ERIKD+LL+EEEFV+N E LKP E+K Sbjct: 30 KFGRKKRK-GGPATAEKLPNIYPSTRCKLKLLRMERIKDHLLLEEEFVSNSEILKPFEKK 88 Query: 350 AEEDRSKVDDLRGSPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAIL 529 EE++ +++++RG+P+S+G LEE+ID++HAIV+S P+YYV ILSFVDK+ LEPGC++L Sbjct: 89 QEEEKKQLEEIRGNPLSIGTLEEIIDDDHAIVTSPTMPDYYVSILSFVDKELLEPGCSVL 148 Query: 530 MHNKVLSVVGLLQDEVDPMVSVMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELY 709 +H+K +S+VG+LQD+ DPMVSVMK++K+P ESY+DIGGL++QIQEIKE+VELPLTHPELY Sbjct: 149 LHHKTMSIVGVLQDDADPMVSVMKMDKSPTESYSDIGGLESQIQEIKESVELPLTHPELY 208 Query: 710 EDIGIRPPKGVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELF 889 E++GI+PPKGVILYG PGTGKTLLAKAVAN TSATFLR+VGSELIQKYLGDGP+L R++F Sbjct: 209 EEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLCRQIF 268 Query: 890 RVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILAT 1069 +VA + +PSIVFIDEIDA+GTKRYD++SGGEREIQRTMLELLNQLDGFD RGDVKVI+AT Sbjct: 269 KVAGENAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDDRGDVKVIMAT 328 Query: 1070 NRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFS 1249 N+IE+LDPAL+RPGRIDRKI F PD+ T+++I IHTS+M L++DVNLE V TKD+ S Sbjct: 329 NKIETLDPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLSEDVNLETLVTTKDDLS 388 Query: 1250 GADIKAICTEAGLLALRERRMKVTHADFXXXXXXXXXXXXEGVPEGLYM 1396 GADI+A+CTEAGLLALRERRM+VT DF E EGLY+ Sbjct: 389 GADIQAMCTEAGLLALRERRMQVTAEDFKQAKERVMKNKVEENLEGLYL 437 >sp|P46507|PRS6B_MANSE 26S protease regulatory subunit 6B OS=Manduca sexta PE=2 SV=1 Length = 415 Score = 387 bits (993), Expect = 1e-106 Identities = 193/379 (50%), Positives = 275/379 (72%), Gaps = 8/379 (2%) Frame = +2 Query: 200 GPEAAARLPTVTPLTKCKLRLLKLERIKDYLLMEEEFVTNQER-LKPQEEKAEEDRSKVD 376 GP+ L + TK K KL+R+ ++L ++EE++ +++R LK + A+E+ ++ Sbjct: 25 GPQTFDELESEDLYTKYK----KLQRMLEFLEVQEEYIKDEQRNLKKEYLHAQEEVKRIQ 80 Query: 377 DLRGSPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVV 556 + P+ +G E +D+N IV S+ G YYV ILS +D++ L+P ++ +H ++V Sbjct: 81 SV---PLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKHSNALV 137 Query: 557 GLLQDEVDPMVSVMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPK 736 +L E D +S+++ ++ P Y+DIGG+D Q QEI+EAVELPLTH ELY IGI PP+ Sbjct: 138 DVLPPEADSSISMLQADEKPDVQYSDIGGMDTQKQEIREAVELPLTHVELYRQIGIEPPR 197 Query: 737 GVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPS 916 GV++YG PG GKT+LA AVA+ T+A F+RVVGSE +QKYLG+GP++VR++FR+A + SP+ Sbjct: 198 GVLMYGPPGCGKTMLANAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENSPA 257 Query: 917 IVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPA 1096 I+FIDEIDA+ TKR+DA +G +RE+QR +LELLNQ+DGFD +VKVI+ATNR ++LDPA Sbjct: 258 IIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPA 317 Query: 1097 LLRPGRIDRKIEFPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICT 1276 LLRPGR+DRKIEFPLPD + +R IF T++M L+++V+LEEFV D SGADI AIC Sbjct: 318 LLRPGRLDRKIEFPLPDRRQKRLIFSTITAKMNLSEEVDLEEFVARPDRVSGADINAICQ 377 Query: 1277 EAGLLALRERRMKVTHADF 1333 EAG+ A+RE R V DF Sbjct: 378 EAGMNAVRENRYIVLPKDF 396 >sp|P46502|PRS6B_CAEEL Probable 26S protease regulatory subunit 6B OS=Caenorhabditis elegans GN=rpt-3 PE=2 SV=1 Length = 414 Score = 385 bits (988), Expect = 5e-106 Identities = 189/360 (52%), Positives = 269/360 (74%), Gaps = 4/360 (1%) Frame = +2 Query: 254 LRLLKLERIKDYLLMEEEFVTNQER-LKPQEEKAEEDRSKVDDLRGSPMSVGNLEELIDE 430 ++L LER +L + E+++ + R L+ + A+E+ ++ + P+ +G E +D+ Sbjct: 38 IKLTTLERQLAHLQVMEDYIKLETRNLEKELLHAQEEVKRIQSV---PLVIGQFLEAVDQ 94 Query: 431 NHAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEK 610 NHAIV S+ G YYV +LS +D++ L+PGC++ +H ++V +L E D + +++ ++ Sbjct: 95 NHAIVGSTTGSNYYVRVLSILDRELLKPGCSVALHKYSNALVDVLPPEADSSIQMLRPDE 154 Query: 611 APLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKA 790 P SY DIGGLD Q QE++EAVELPLTH ELY+ IGI PP+GV++YG PG GKT+LAKA Sbjct: 155 KPDISYGDIGGLDMQKQEVREAVELPLTHGELYQQIGIDPPRGVLMYGPPGCGKTMLAKA 214 Query: 791 VANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAH 970 VA +T+A+F+RVVGSE +QKYLG+GP++VR++FR+A + SPSI+FIDEIDA+ TKR+DA Sbjct: 215 VAANTAASFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENSPSIIFIDEIDAIATKRFDAQ 274 Query: 971 SGGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDI 1150 +G +RE+QR +LELLNQ+DGFD +VKVI+ATNR ++LDPALLRPGR+DRKIEFPLPD Sbjct: 275 TGADREVQRILLELLNQMDGFDQSTNVKVIMATNRQDTLDPALLRPGRLDRKIEFPLPDR 334 Query: 1151 KTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHAD 1330 + +R +F SRM L+DDV+LE++V D+ SGADI +IC EAG+ A+RE R V D Sbjct: 335 RQKRLVFSTVCSRMNLSDDVDLEDWVARPDKISGADINSICQEAGMQAVRENRYVVLTKD 394 >sp|Q9SEI4|PRS6B_ARATH 26S protease regulatory subunit 6B homolog OS=Arabidopsis thaliana GN=RPT3 PE=2 SV=1 Length = 408 Score = 380 bits (975), Expect = 2e-104 Identities = 185/360 (51%), Positives = 269/360 (74%), Gaps = 4/360 (1%) Frame = +2 Query: 257 RLLKLERIKDYLLMEEEFVTN-QERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEELIDEN 433 RL LER ++ ++EE+V + Q+ LK + +A+E+ ++ + P+ +G E++D+N Sbjct: 33 RLKSLERQLEFTDIQEEYVKDEQKNLKRELLRAQEEVKRIQSV---PLVIGQFMEMVDQN 89 Query: 434 HAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEKA 613 + IV S+ G YYV ILS ++++ L+P ++ +H ++V +L E D +S++ + Sbjct: 90 NGIVGSTTGSNYYVRILSTINRELLKPSASVALHRHSNALVDVLPPEADSSISLLSQSEK 149 Query: 614 PLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAV 793 P SY DIGG D Q QEI+EAVELPLTH ELY+ IGI PP+GV+LYG PGTGKT+LAKAV Sbjct: 150 PDVSYNDIGGCDIQKQEIREAVELPLTHHELYKQIGIDPPRGVLLYGPPGTGKTMLAKAV 209 Query: 794 ANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHS 973 AN T+A F+RVVGSE +QKYLG+GP++VR++FR+A + +P+I+FIDE+DA+ T R+DA + Sbjct: 210 ANHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEVDAIATARFDAQT 269 Query: 974 GGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIK 1153 G +RE+QR ++ELLNQ+DGFD +VKVI+ATNR ++LDPALLRPGR+DRKIEFPLPD + Sbjct: 270 GADREVQRILMELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRR 329 Query: 1154 TRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADF 1333 +R +FQ+ TS+M L+D+V+LE++V D+ S A+I AIC EAG+ A+R+ R + DF Sbjct: 330 QKRLVFQVCTSKMNLSDEVDLEDYVSRPDKISAAEIAAICQEAGMHAVRKNRYVILPKDF 389 >sp|O28303|PSMR_ARCFU Proteasome-activating nucleotidase OS=Archaeoglobus fulgidus GN=pan PE=3 SV=1 Length = 398 Score = 380 bits (974), Expect = 2e-104 Identities = 190/365 (52%), Positives = 266/365 (72%), Gaps = 2/365 (0%) Frame = +2 Query: 239 LTKCKLRLLKLERIKDYLLMEEEFVTNQERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEE 418 L K + KL + L E++F+ ER++ E + RS+V+ LR P+ VG + + Sbjct: 13 LKKLEEDYYKLRELYRRLEDEKKFI-ESERIR-YEREVRRLRSEVERLRSPPLLVGVVSD 70 Query: 419 LIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVM 598 ++++ +V SS GP++ V ++++++L+PG + ++ + L++V +L DPMV Sbjct: 71 ILEDGRVVVKSSTGPKFVVNTSQYINEEELKPGARVALNQQTLAIVNVLPTSKDPMVYGF 130 Query: 599 KVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTL 778 +VE+ P SY DIGGLD QI+EI+EAVELPL PEL+ ++GI PPKGV+LYG PGTGKTL Sbjct: 131 EVEEKPEVSYEDIGGLDVQIEEIREAVELPLLKPELFAEVGIEPPKGVLLYGPPGTGKTL 190 Query: 779 LAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKR 958 LAKAVAN T ATF+RVVGSE +QKY+G+G +LVRE+F++A + +PSI+FIDE+DA+ +R Sbjct: 191 LAKAVANQTRATFIRVVGSEFVQKYIGEGARLVREVFQLAKEKAPSIIFIDELDAIAARR 250 Query: 959 YDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFP 1138 ++ + G+RE+QRTM++LL +LDGFD RGDVKVI ATNRI+ LDPA+LRPGR DR IE P Sbjct: 251 TNSDTSGDREVQRTMMQLLAELDGFDPRGDVKVIGATNRIDILDPAILRPGRFDRIIEVP 310 Query: 1139 LPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKV 1318 LP + R +IF+IHT +M LA+DV+ +E + SGADIKAICTEAG+ A+RE R KV Sbjct: 311 LPTFEGRIQIFKIHTRKMKLAEDVDFKELARITEGASGADIKAICTEAGMFAIREERAKV 370 Query: 1319 THADF 1333 T DF Sbjct: 371 TMLDF 375 >sp|Q3T030|PRS6B_BOVIN 26S protease regulatory subunit 6B OS=Bos taurus GN=PSMC4 PE=2 SV=1 Length = 418 Score = 379 bits (972), Expect = 4e-104 Identities = 185/360 (51%), Positives = 269/360 (74%), Gaps = 4/360 (1%) Frame = +2 Query: 257 RLLKLERIKDYLLMEEEFVTN-QERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEELIDEN 433 R KL++ ++L ++EE++ + Q+ LK + A+E+ ++ + P+ +G E +D+N Sbjct: 43 RYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSI---PLVIGQFLEAVDQN 99 Query: 434 HAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEKA 613 AIV S+ G YYV ILS +D++ L+P ++ +H ++V +L E D + ++ ++ Sbjct: 100 TAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQK 159 Query: 614 PLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAV 793 P YADIGG+D Q QE++EAVELPLTH ELY+ IGI PP+GV++YG PG GKT+LAKAV Sbjct: 160 PDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAV 219 Query: 794 ANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHS 973 A+ T+A F+RVVGSE +QKYLG+GP++VR++FR+A + +P+I+FIDEIDA+ TKR+DA + Sbjct: 220 AHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQT 279 Query: 974 GGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIK 1153 G +RE+QR +LELLNQ+DGFD +VKVI+ATNR ++LDPALLRPGR+DRKIEFPLPD + Sbjct: 280 GADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRR 339 Query: 1154 TRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADF 1333 +R IF TS+M L+++V+LE++V D+ SGADI +IC E+G+LA+RE R V DF Sbjct: 340 QKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDF 399 >sp|P43686|PRS6B_HUMAN 26S protease regulatory subunit 6B OS=Homo sapiens GN=PSMC4 PE=1 SV=2 Length = 418 Score = 379 bits (972), Expect = 4e-104 Identities = 185/360 (51%), Positives = 269/360 (74%), Gaps = 4/360 (1%) Frame = +2 Query: 257 RLLKLERIKDYLLMEEEFVTN-QERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEELIDEN 433 R KL++ ++L ++EE++ + Q+ LK + A+E+ ++ + P+ +G E +D+N Sbjct: 43 RYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSI---PLVIGQFLEAVDQN 99 Query: 434 HAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEKA 613 AIV S+ G YYV ILS +D++ L+P ++ +H ++V +L E D + ++ ++ Sbjct: 100 TAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQK 159 Query: 614 PLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAV 793 P YADIGG+D Q QE++EAVELPLTH ELY+ IGI PP+GV++YG PG GKT+LAKAV Sbjct: 160 PDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAV 219 Query: 794 ANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHS 973 A+ T+A F+RVVGSE +QKYLG+GP++VR++FR+A + +P+I+FIDEIDA+ TKR+DA + Sbjct: 220 AHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQT 279 Query: 974 GGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIK 1153 G +RE+QR +LELLNQ+DGFD +VKVI+ATNR ++LDPALLRPGR+DRKIEFPLPD + Sbjct: 280 GADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRR 339 Query: 1154 TRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADF 1333 +R IF TS+M L+++V+LE++V D+ SGADI +IC E+G+LA+RE R V DF Sbjct: 340 QKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDF 399 >sp|Q4R7L3|PRS6B_MACFA 26S protease regulatory subunit 6B OS=Macaca fascicularis GN=PSMC4 PE=2 SV=1 Length = 418 Score = 379 bits (972), Expect = 4e-104 Identities = 185/360 (51%), Positives = 269/360 (74%), Gaps = 4/360 (1%) Frame = +2 Query: 257 RLLKLERIKDYLLMEEEFVTN-QERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEELIDEN 433 R KL++ ++L ++EE++ + Q+ LK + A+E+ ++ + P+ +G E +D+N Sbjct: 43 RYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSI---PLVIGQFLEAVDQN 99 Query: 434 HAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEKA 613 AIV S+ G YYV ILS +D++ L+P ++ +H ++V +L E D + ++ ++ Sbjct: 100 TAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQK 159 Query: 614 PLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAV 793 P YADIGG+D Q QE++EAVELPLTH ELY+ IGI PP+GV++YG PG GKT+LAKAV Sbjct: 160 PDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAV 219 Query: 794 ANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHS 973 A+ T+A F+RVVGSE +QKYLG+GP++VR++FR+A + +P+I+FIDEIDA+ TKR+DA + Sbjct: 220 AHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQT 279 Query: 974 GGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIK 1153 G +RE+QR +LELLNQ+DGFD +VKVI+ATNR ++LDPALLRPGR+DRKIEFPLPD + Sbjct: 280 GADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRR 339 Query: 1154 TRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADF 1333 +R IF TS+M L+++V+LE++V D+ SGADI +IC E+G+LA+RE R V DF Sbjct: 340 QKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDF 399 >sp|Q63570|PRS6B_RAT 26S protease regulatory subunit 6B OS=Rattus norvegicus GN=Psmc4 PE=1 SV=1 Length = 418 Score = 379 bits (972), Expect = 4e-104 Identities = 185/360 (51%), Positives = 269/360 (74%), Gaps = 4/360 (1%) Frame = +2 Query: 257 RLLKLERIKDYLLMEEEFVTN-QERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEELIDEN 433 R KL++ ++L ++EE++ + Q+ LK + A+E+ ++ + P+ +G E +D+N Sbjct: 43 RYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSI---PLVIGQFLEAVDQN 99 Query: 434 HAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEKA 613 AIV S+ G YYV ILS +D++ L+P ++ +H ++V +L E D + ++ ++ Sbjct: 100 TAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQK 159 Query: 614 PLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAV 793 P YADIGG+D Q QE++EAVELPLTH ELY+ IGI PP+GV++YG PG GKT+LAKAV Sbjct: 160 PDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAV 219 Query: 794 ANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHS 973 A+ T+A F+RVVGSE +QKYLG+GP++VR++FR+A + +P+I+FIDEIDA+ TKR+DA + Sbjct: 220 AHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQT 279 Query: 974 GGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIK 1153 G +RE+QR +LELLNQ+DGFD +VKVI+ATNR ++LDPALLRPGR+DRKIEFPLPD + Sbjct: 280 GADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRR 339 Query: 1154 TRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADF 1333 +R IF TS+M L+++V+LE++V D+ SGADI +IC E+G+LA+RE R V DF Sbjct: 340 QKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDF 399 >sp|P54778|PRS6B_SOLTU 26S protease regulatory subunit 6B homolog OS=Solanum tuberosum PE=2 SV=1 Length = 413 Score = 372 bits (954), Expect = 4e-102 Identities = 180/360 (50%), Positives = 269/360 (74%), Gaps = 4/360 (1%) Frame = +2 Query: 257 RLLKLERIKDYLLMEEEFVTNQ-ERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEELIDEN 433 RL L+R +++ ++EE+V ++ + L+ + +A+E+ ++ + P+ +G E+ID+N Sbjct: 38 RLKSLQRQLEFIEIQEEYVKDELKNLRREHLRAQEEVKRIQSV---PLVIGQFMEMIDQN 94 Query: 434 HAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEKA 613 +AIV S+ G YYV ILS ++++ L+P ++ + ++V +L E D +S++ + Sbjct: 95 NAIVGSTTGSNYYVRILSTINRELLKPSASVGLDRHSNALVDVLPPEADSSISLLSQSEK 154 Query: 614 PLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAV 793 P +Y DIGG D Q QEI+EAVELPLTH ELY+ IGI PP+GV+LYG PGTGKT+LAKAV Sbjct: 155 PDVTYNDIGGCDIQKQEIREAVELPLTHHELYKQIGIDPPRGVLLYGPPGTGKTMLAKAV 214 Query: 794 ANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHS 973 A+ T+A F+RVVGSE +QKYLG+GP++VR++FR+A + +P+I+FIDE+DA+ T R+DA + Sbjct: 215 AHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEVDAIATARFDAQT 274 Query: 974 GGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIK 1153 G +RE+QR ++ELLNQ+DGFD +VKVI+ATNR ++LDPALLRPGR+DRKIEFPLPD + Sbjct: 275 GADREVQRILMELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRR 334 Query: 1154 TRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADF 1333 +R +FQ+ T++M L D+V+LE++V D+ S A+I AIC EAG+ A+R+ R + DF Sbjct: 335 QKRLVFQVCTAKMNLGDEVDLEDYVSRPDKISAAEITAICQEAGMHAVRKNRYVILPKDF 394 >sp|P54775|PRS6B_MOUSE 26S protease regulatory subunit 6B OS=Mus musculus GN=Psmc4 PE=1 SV=1 Length = 418 Score = 369 bits (946), Expect = 4e-101 Identities = 180/360 (50%), Positives = 266/360 (73%), Gaps = 4/360 (1%) Frame = +2 Query: 257 RLLKLERIKDYLLMEEEFVTN-QERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEELIDEN 433 R KL++ ++L ++EE++ + Q+ LK + A+E+ ++ + P+ +G E +D+N Sbjct: 43 RYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSI---PLVIGQFLEAVDQN 99 Query: 434 HAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEKA 613 AIV+S+ G YYV ++S +D++ L+P ++ +H ++V +L D + ++ ++ Sbjct: 100 TAIVASTTGSNYYVRMVSTIDRELLKPNASVALHKHSNALVDVLPPAADSSIMMLTSDQK 159 Query: 614 PLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAV 793 P YADIGG+D Q QE++EAVELPLTH ELY+ IGI PP+GV++YG PG GKT+LAKAV Sbjct: 160 PDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAV 219 Query: 794 ANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHS 973 A+ T+A F+RVVGSE +QKYLG+GP++VR++FR+A + +P+I+FIDEIDA+ TKR+DA + Sbjct: 220 AHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQT 279 Query: 974 GGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIK 1153 G +RE+QR +LELLNQ+DGFD +VKVI+ATNR ++LDPALLRPGR+DRKIEFPLPD + Sbjct: 280 GADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRR 339 Query: 1154 TRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADF 1333 +R IF TS+M L+++V+LE++V D+ SGADI +IC G+LA+RE V DF Sbjct: 340 QKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQARGMLAVRETAYIVLAKDF 399 >sp|P34123|PRS6B_DICDI 26S protease regulatory subunit 6B homolog OS=Dictyostelium discoideum GN=psmC4 PE=2 SV=1 Length = 403 Score = 368 bits (944), Expect = 6e-101 Identities = 185/360 (51%), Positives = 265/360 (73%), Gaps = 4/360 (1%) Frame = +2 Query: 257 RLLKLERIKDYLLMEEEFVTNQ-ERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEELIDEN 433 ++ LE D+ ++EE++ + + LK + A+E+ V +R P+ +G L E++D N Sbjct: 28 KMKSLESKLDFFNIQEEYIKYEYKNLKRELLHAQEE---VKRIRSVPLLIGQLLEMVDSN 84 Query: 434 HAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEKA 613 IV S+ G V ILS +D++ L+P ++ + ++V L E D + ++ ++ Sbjct: 85 TGIVQSTSGSTLCVRILSTIDRELLKPSASVALQRHSNALVDTLPPESDSSIHLLGADEK 144 Query: 614 PLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAV 793 P ESY+DIGG D Q QE++EAVELPLTH LY+ IGI PP+GV+LYG PGTGKT+LAKAV Sbjct: 145 PSESYSDIGGGDIQKQEMREAVELPLTHHNLYKQIGIDPPRGVLLYGPPGTGKTMLAKAV 204 Query: 794 ANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHS 973 A+ TSA F+RVVGSE +QKYLG+GP+LVR++FR+A + SP+I+FIDEIDA+ TKR+DA + Sbjct: 205 AHHTSAAFIRVVGSEFVQKYLGEGPRLVRDVFRLARENSPAIIFIDEIDAIATKRFDAQT 264 Query: 974 GGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIK 1153 G +RE+QR ++ELLNQ+DGFD +VKVI+ATNR ++LDPALLRPGR+DRKIEFPLPD + Sbjct: 265 GADREVQRILMELLNQMDGFDVSVNVKVIMATNRQDTLDPALLRPGRLDRKIEFPLPDRR 324 Query: 1154 TRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADF 1333 +R IFQ+ TS+M L+D+V+LE++V D+ SGA+I++IC EAG+ A+R+ R + DF Sbjct: 325 QKRLIFQVITSKMNLSDEVDLEDYVSRPDKLSGAEIQSICQEAGMHAIRKNRYVILPKDF 384 >sp|Q8SQI9|PRS6B_ENCCU 26S protease regulatory subunit 6B homolog OS=Encephalitozoon cuniculi GN=ECU08_1970 PE=3 SV=1 Length = 387 Score = 361 bits (926), Expect = 8e-099 Identities = 181/360 (50%), Positives = 252/360 (70%), Gaps = 2/360 (0%) Frame = +2 Query: 254 LRLLKLERIKDYLLMEEEFVTNQERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEELIDEN 433 +R ++ER L + E +V + +EE+ R ++D ++ P+ +G E ID + Sbjct: 11 VRYKQMERKLRLLEIREGYVRKEIETLKREER--HSREELDRVKSVPLIMGQFLEPIDSS 68 Query: 434 HAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEKA 613 AIV S+ G + V ILS VD++ L+P + +H ++VG+L EVD + VM + Sbjct: 69 TAIVGSTAGSNFVVRILSTVDRELLKPNTTVALHRHSSAIVGVLPPEVDSTIPVMGESEK 128 Query: 614 PLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAV 793 P +Y D+GGLD Q QEIKE VELPL +LY IGI PP+GV+LYG PGTGKT+L KAV Sbjct: 129 PSVTYGDVGGLDVQKQEIKETVELPLLQSDLYRQIGIDPPQGVLLYGPPGTGKTMLVKAV 188 Query: 794 ANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHS 973 AN T ATF+RV GSE +QKYLG+GP++VR++FR+A + +PSIVFIDE+D++ TKR+DA + Sbjct: 189 ANHTKATFIRVNGSEFVQKYLGEGPRMVRDVFRLAREKAPSIVFIDEVDSIATKRFDAST 248 Query: 974 GGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIK 1153 +RE+QR ++ELLNQ+DGFD +VKVI+ATNR +++DPALLRPGR+DRKIEFPLPD + Sbjct: 249 SADREVQRVLIELLNQMDGFDPAANVKVIMATNRADTIDPALLRPGRLDRKIEFPLPDRR 308 Query: 1154 TRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADF 1333 +R +F TS+M+L D V++E V ++ S ADI +IC EAG+LA+R R VT DF Sbjct: 309 QKRLVFNAITSKMSLNDSVDIESLVCRPEKISCADINSICQEAGMLAVRASRYMVTQRDF 368 >sp|Q58576|PSMR_METJA Proteasome-activating nucleotidase OS=Methanocaldococcus jannaschii GN=pan PE=1 SV=1 Length = 430 Score = 359 bits (921), Expect = 3e-098 Identities = 186/362 (51%), Positives = 257/362 (70%), Gaps = 4/362 (1%) Frame = +2 Query: 251 KLRLLKLE-RIKDYLLMEEEFVTNQERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEELID 427 K R+ +LE RI L ++E +E L+ +E E R ++D +R P+ VG + + + Sbjct: 46 KARIAELESRILKLELEKKEL--ERENLQLMKEN-EILRRELDRMRVPPLIVGTVVDKVG 102 Query: 428 ENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVE 607 E +V SS GP + V + FV+ D L PG + ++ + L+VV +L + D M+V+ Sbjct: 103 ERKVVVKSSTGPSFLVNVSHFVNPDDLAPGKRVCLNQQTLTVVDVLPENKDYRAKAMEVD 162 Query: 608 KAPLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAK 787 + P Y DIGGL+ Q+QEI+E VELPL HPEL+E +GI PPKG++LYG PGTGKTLLAK Sbjct: 163 ERPNVRYEDIGGLEKQMQEIREVVELPLKHPELFEKVGIEPPKGILLYGPPGTGKTLLAK 222 Query: 788 AVANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDA 967 AVA T+ATF+RVVGSEL++K++G+G LV+++F++A + +PSI+FIDEIDA+ KR DA Sbjct: 223 AVATETNATFIRVVGSELVKKFIGEGASLVKDIFKLAKEKAPSIIFIDEIDAIAAKRTDA 282 Query: 968 HSGGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPD 1147 +GG+RE+QRT+++LL ++DGFD+RGDVK+I ATNR + LDPA+LRPGR DR IE P PD Sbjct: 283 LTGGDREVQRTLMQLLAEMDGFDARGDVKIIGATNRPDILDPAILRPGRFDRIIEVPAPD 342 Query: 1148 IKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHA 1327 K R I +IHT +M LA+DVNLEE + GA++KAICTEAG+ A+RE R VT Sbjct: 343 EKGRLEILKIHTRKMNLAEDVNLEEIAKMTEGCVGAELKAICTEAGMNAIRELRDYVTMD 402 Query: 1328 DF 1333 DF Sbjct: 403 DF 404 >sp|O26824|PSMR_METTH Proteasome-activating nucleotidase OS=Methanobacterium thermoautotrophicum GN=pan PE=3 SV=1 Length = 410 Score = 359 bits (921), Expect = 3e-098 Identities = 181/359 (50%), Positives = 257/359 (71%), Gaps = 9/359 (2%) Frame = +2 Query: 257 RLLKLERIKDYLLMEEEFVTNQERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEELIDENH 436 ++ KLE KD LL+E E + RL + + + R +++ R P+ + + E++D++ Sbjct: 36 KIRKLE--KDKLLIENE----RTRL---DREVKSLRGEIERFRTPPLVIATVTEVLDDHR 86 Query: 437 AIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEKAP 616 V S+ GP + + F+D+ QLEPG + ++ + S+V +L E DP+V+ M+VE+ P Sbjct: 87 VAVKSTTGPHFVINYSRFIDRKQLEPGARVALNQQTFSIVDVLPSEKDPVVTGMEVEEKP 146 Query: 617 LESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAVA 796 SY IGGL+ Q++E+KE VELPL PEL+E IGI PPKGV+LYG PGTGKTLLAKAVA Sbjct: 147 DVSYEQIGGLEEQVREVKETVELPLKKPELFEKIGIEPPKGVLLYGPPGTGKTLLAKAVA 206 Query: 797 NSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHSG 976 + T+ATF+++V SE ++KY+G+G +LVR +F +A + SPSI+FIDEIDAV KR + + Sbjct: 207 HETNATFIKIVASEFVRKYIGEGARLVRGVFELAKEKSPSIIFIDEIDAVAAKRLKSSTS 266 Query: 977 GEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIKT 1156 G+RE+QRT+++LL +LDGF+SRG+V ++ ATNR + LDPALLRPGR DR IE PLP+ Sbjct: 267 GDREVQRTLMQLLAELDGFESRGNVGIVAATNRPDILDPALLRPGRFDRFIEVPLPNEDG 326 Query: 1157 RRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADF 1333 RR I +IHTS M LA++V++E D SGAD+KAICTEAG+ A+R+ R +VT ADF Sbjct: 327 RREILKIHTSGMALAEEVDIELLARITDGASGADLKAICTEAGMFAIRDERDEVTMADF 385 >sp|Q8TX03|PSMR_METKA Proteasome-activating nucleotidase OS=Methanopyrus kandleri GN=pan PE=3 SV=1 Length = 436 Score = 356 bits (913), Expect = 2e-097 Identities = 181/364 (49%), Positives = 256/364 (70%), Gaps = 1/364 (0%) Frame = +2 Query: 245 KCKLRLLKLERIKDYLLME-EEFVTNQERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEEL 421 K ++ + + ++ L ME +E +E L+ +E E+ RS + ++ P+ VG +EE+ Sbjct: 50 KLRIEARRRKTLEKELEMERDEKAELREELRRKEVMIEKLRSDLQRMKKPPLIVGTVEEI 109 Query: 422 IDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMK 601 +D+ IV SS GP++ + VD+++LEPG + ++ + ++VV +L E D V M+ Sbjct: 110 LDDGRVIVKSSTGPKFVSNVSPTVDRNELEPGANVALNQQSMAVVDVLPSEKDSRVLAME 169 Query: 602 VEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLL 781 V+++P SY DIGGLD QI+EI+E VE PL PEL+E +G+ PPKGV+LYG PGTGKTLL Sbjct: 170 VDESPDVSYDDIGGLDEQIREIREVVEKPLKEPELFEKVGVEPPKGVLLYGPPGTGKTLL 229 Query: 782 AKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRY 961 AKAVAN ATF+R+ EL+QK++G+G +LVRELF +A + +PSI+FIDEIDA+G +R Sbjct: 230 AKAVANHADATFIRLAAPELVQKFIGEGARLVRELFELAREKAPSIIFIDEIDAIGARRM 289 Query: 962 DAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPL 1141 + G+RE+QRT+ +LL ++DGFD D+KVI ATNR + LDPALLRPGR DR I+ PL Sbjct: 290 RDATSGDREVQRTLTQLLAEMDGFDPLDDIKVIAATNRKDILDPALLRPGRFDRHIKIPL 349 Query: 1142 PDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVT 1321 PD + R IF+IHT M LA+DV+L++ + SGADIKAICTEAG++A+RE R VT Sbjct: 350 PDEEGRYEIFKIHTRDMNLAEDVDLQKLAKITEGASGADIKAICTEAGMMAIREDRDIVT 409 Query: 1322 HADF 1333 DF Sbjct: 410 MDDF 413 >sp|A3CV35|PSMR_METMJ Proteasome-activating nucleotidase OS=Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) GN=pan PE=3 SV=1 Length = 412 Score = 350 bits (897), Expect = 2e-095 Identities = 177/365 (48%), Positives = 253/365 (69%), Gaps = 2/365 (0%) Frame = +2 Query: 239 LTKCKLRLLKLERIKDYLLMEEEFVTNQERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEE 418 +T + R L+L + E+ +V Q+ E + + +S+++ LR P+ +G + + Sbjct: 25 ITNLENRNLELREQFRQMESEKRYVETQK--IRYERELRKLKSEIEQLRSPPLVIGTVTD 82 Query: 419 LIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVM 598 +ID + IV SS GP + V +D D L+PG ++ + L++V +L D + M Sbjct: 83 VIDNSRVIVRSSAGPRFLVRTSQLIDPDLLKPGVRCTLNQQSLAIVDVLPTSYDAQIYGM 142 Query: 599 KVEKAPLESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTL 778 ++ ++P E+Y +IGGL+ QI+EI+EAVELPLT P+L+E +GI PPKGV+LYG PGTGKTL Sbjct: 143 ELVESPEETYENIGGLEPQIEEIREAVELPLTKPQLFEKVGISPPKGVLLYGPPGTGKTL 202 Query: 779 LAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKR 958 LA+AVA+ T+A FLRVVGSEL+QKY+G+G +LVRELF +A +PSI+FIDEIDA+G R Sbjct: 203 LARAVAHQTNAHFLRVVGSELVQKYIGEGARLVRELFDLAKQRAPSIIFIDEIDAIGAHR 262 Query: 959 YDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFP 1138 D+ + G+RE+QRT+++LL ++DGFD+RGDVK++ ATNRI+ LD ALLRPGR DR IE P Sbjct: 263 NDSTTSGDREVQRTLMQLLAEMDGFDNRGDVKIVAATNRIDILDRALLRPGRFDRMIEIP 322 Query: 1139 LPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKV 1318 LPD + R I +IHT M + +DVNL E + +GAD++AIC EAG+ A+R R V Sbjct: 323 LPDHQGRLAILKIHTQYMNIGEDVNLSEVSRLTEGKNGADLRAICMEAGMFAIRMERDAV 382 Query: 1319 THADF 1333 DF Sbjct: 383 NSEDF 387 >sp|Q0W257|PSMR_UNCMA Proteasome-activating nucleotidase OS=Uncultured methanogenic archaeon RC-I GN=pan PE=3 SV=1 Length = 417 Score = 343 bits (878), Expect = 3e-093 Identities = 167/351 (47%), Positives = 245/351 (69%) Frame = +2 Query: 281 KDYLLMEEEFVTNQERLKPQEEKAEEDRSKVDDLRGSPMSVGNLEELIDENHAIVSSSVG 460 ++Y +E E + + + E + + S++D L+ P+ VG + +++ I+ SS G Sbjct: 43 EEYRKIELEKKSVENKKVQYEREIRKLTSELDRLKTPPLIVGTILDVMANGKMIIKSSTG 102 Query: 461 PEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEKAPLESYADIG 640 P++ V F++ ++ PG + ++ + L+V+ +L DP V M+V +P Y IG Sbjct: 103 PKFVVNSSQFINSKEVYPGAKVALNQQSLAVIEVLPTVKDPSVLGMEVVDSPEIDYQSIG 162 Query: 641 GLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAVANSTSATFL 820 GL+AQI E+KE VELPL PEL++ +GI PPKGV+LYG PGTGKTLLAKAVAN T ATF+ Sbjct: 163 GLEAQINELKETVELPLLKPELFQKVGIEPPKGVLLYGPPGTGKTLLAKAVANRTKATFI 222 Query: 821 RVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRT 1000 R++GSEL+QKY+G+G ++VRELF +A + SPSI+FIDEID++G KR D+ + G+RE+QRT Sbjct: 223 RIIGSELVQKYIGEGARMVRELFELAKEKSPSIIFIDEIDSIGAKRLDSITSGDREVQRT 282 Query: 1001 MLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIH 1180 +++LL ++DGFD RG+V+++ ATNR + LDPALLRPGR DR I+ P+P + R +I +IH Sbjct: 283 LVQLLAEMDGFDPRGNVRILAATNRPDILDPALLRPGRFDRMIKVPMPTAEAREQILKIH 342 Query: 1181 TSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADF 1333 +M LADDV+L + + DE SGAD+ AI EAG+ A+R R V +DF Sbjct: 343 ARKMNLADDVDLRKIALITDESSGADLSAIVMEAGMFAIRNNRDVVDSSDF 393 >sp|A7I8B8|PSMR_METB6 Proteasome-activating nucleotidase OS=Methanoregula boonei (strain 6A8) GN=pan PE=3 SV=1 Length = 436 Score = 340 bits (871), Expect = 2e-092 Identities = 169/331 (51%), Positives = 233/331 (70%) Frame = +2 Query: 341 EEKAEEDRSKVDDLRGSPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGC 520 E + + +S+ + LR P+ +G + +++D N IV SS GP + V V+ D ++PG Sbjct: 82 EREVRKLKSESEQLRSPPLIIGTVVDVVDANRVIVRSSAGPRFLVRSSPSVNPDDIKPGA 141 Query: 521 AILMHNKVLSVVGLLQDEVDPMVSVMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHP 700 ++ + L++V LL D V M++ +P E Y DIGGL QI E++EAVELPL P Sbjct: 142 RCTLNQQSLAIVELLPSSFDAQVYGMELVDSPQECYTDIGGLKEQINEVREAVELPLKRP 201 Query: 701 ELYEDIGIRPPKGVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVR 880 EL+ IGI PPKGV+LYG PGTGKTLLAKAVA+ T+A F+RVVGSEL+QKY+G+G +LVR Sbjct: 202 ELFTQIGIEPPKGVLLYGPPGTGKTLLAKAVAHETNAHFMRVVGSELVQKYIGEGARLVR 261 Query: 881 ELFRVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVI 1060 ELF +A +P+I+FIDEIDAVG R +A++ G+RE+QRT+++LL +DGF++RGDVK+I Sbjct: 262 ELFDLAKKKAPTIIFIDEIDAVGASRTEANTSGDREVQRTLMQLLAGMDGFETRGDVKII 321 Query: 1061 LATNRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKD 1240 ATNRI+ LD ALLRPGR DR IE PLPD + R I ++HT +T+ + VNL E + Sbjct: 322 GATNRIDILDKALLRPGRFDRIIEIPLPDEEGRLSILKVHTRTLTMEETVNLPEIAGLTE 381 Query: 1241 EFSGADIKAICTEAGLLALRERRMKVTHADF 1333 +GAD++AIC EAG+ A+R R +T DF Sbjct: 382 GKNGADLRAICMEAGMYAIRNERPAITREDF 412 >sp|O18413|PRS8_DROME 26S protease regulatory subunit 8 OS=Drosophila melanogaster GN=Pros45 PE=1 SV=2 Length = 405 Score = 335 bits (857), Expect = 8e-091 Identities = 170/359 (47%), Positives = 249/359 (69%), Gaps = 4/359 (1%) Frame = +2 Query: 269 LERIKDYLLMEEEFVTNQERLKPQEE----KAEEDRSKVDDLRGSPMSVGNLEELIDENH 436 +++I++ L+ E N RL+ Q K R ++ L+ VG + + +D+ Sbjct: 24 IQKIEELQLVVAEKHQNLRRLQAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKK 83 Query: 437 AIVSSSVGPEYYVGILSFVDKDQLEPGCAILMHNKVLSVVGLLQDEVDPMVSVMKVEKAP 616 +V ++ V + +D + + P C + + N+ ++ +L ++VDP+VS+M VEK P Sbjct: 84 VLVKVHPEGKFVVDLDKNIDINDVTPNCRVALRNESYTLHKILPNKVDPLVSLMMVEKVP 143 Query: 617 LESYADIGGLDAQIQEIKEAVELPLTHPELYEDIGIRPPKGVILYGEPGTGKTLLAKAVA 796 +Y +GGLD QI+EIKE +ELP+ HPEL++ +GI PKGV+LYG PGTGKTLLA+AVA Sbjct: 144 DSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVA 203 Query: 797 NSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHSG 976 + T TF+RV GSEL+QK++G+G ++VRELF +A + +PSI+F+DEID++G+ R ++ SG Sbjct: 204 HHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRIESGSG 263 Query: 977 GEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIKT 1156 G+ E+QRTMLELLNQLDGF++ ++KVI+ATNRI+ LDPALLRPGRIDRKIEFP P+ + Sbjct: 264 GDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPNEEA 323 Query: 1157 RRRIFQIHTSRMTLADDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHADF 1333 R I +IH+ +M L +NL + SGA++K +CTEAG+ ALRERR+ VT DF Sbjct: 324 RLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDF 382 >sp|Q2FQ56|PSMR_METHJ Proteasome-activating nucleotidase OS=Methanospirillum hungatei (strain JF-1 / DSM 864) GN=pan PE=3 SV=1 Length = 412 Score = 335 bits (857), Expect = 8e-091 Identities = 167/331 (50%), Positives = 232/331 (70%) Frame = +2 Query: 341 EEKAEEDRSKVDDLRGSPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGC 520 E + + +S+++ L+ P+ VG + ++ID +V SS GP + V + V+ L+ G Sbjct: 57 EREVRKLKSEIEHLKTPPLIVGTITDIIDSGRVVVRSSAGPRFLVRVSQAVNPTTLKAGV 116 Query: 521 AILMHNKVLSVVGLLQDEVDPMVSVMKVEKAPLESYADIGGLDAQIQEIKEAVELPLTHP 700 ++ + L++V +L D V M++ AP E+Y DIGGL+ QI EI+EAVELP+T P Sbjct: 117 RCTLNQQSLAIVEVLPSTYDSQVYGMELVDAPTETYEDIGGLEKQIMEIREAVELPMTRP 176 Query: 701 ELYEDIGIRPPKGVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVR 880 +L+E IGI PPKGV+LYG PGTGKTLLAKAVA+ T A FL VGSEL+QKY+G+G +LVR Sbjct: 177 DLFEKIGINPPKGVLLYGPPGTGKTLLAKAVAHETHAIFLHTVGSELVQKYIGEGARLVR 236 Query: 881 ELFRVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVI 1060 ELF +A + +PSIVFIDEIDA+G R +A + G+RE+QRT+++LL +DGF+ RGDVK+I Sbjct: 237 ELFDLAKEKAPSIVFIDEIDAIGASRTEAMTSGDREVQRTLMQLLAAMDGFEPRGDVKII 296 Query: 1061 LATNRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIHTSRMTLADDVNLEEFVMTKD 1240 ATNRI+ LD ALLRPGR DR IE PLPD + R I ++HT M L++DV+L E + Sbjct: 297 GATNRIDILDAALLRPGRFDRIIEIPLPDTEGRYSILKVHTRCMNLSEDVDLMEVARLTE 356 Query: 1241 EFSGADIKAICTEAGLLALRERRMKVTHADF 1333 +GA++ AIC EAG+ A+R+ +V DF Sbjct: 357 GRNGAELNAICMEAGMFAIRKEHPQVDQEDF 387 Database: UniProt/Swiss-Prot Posted date: Thu Apr 23 14:22:33 2009 Number of letters in database: 163,773,382 Number of sequences in database: 462,764 Lambda K H 0.267 0.041 0.140 Gapped Lambda K H 0.267 0.041 0.140 Matrix: blosum62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 3,407,642,047 Number of Sequences: 462764 Number of Extensions: 3407642047 Number of Successful Extensions: 34563130 Number of sequences better than 0.0: 0 |