BLASTX 7.6.2
Query= RU02026 /QuerySize=744
(743 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q93YF5|SUVH1_TOBAC Histone-lysine N-methyltransferase, H3 lys... 354 5e-097
sp|Q9C5P4|SUVH3_ARATH Histone-lysine N-methyltransferase, H3 lys... 261 5e-069
sp|Q9FF80|SUVH1_ARATH Histone-lysine N-methyltransferase, H3 lys... 240 1e-062
sp|Q9C5P0|SUVH8_ARATH Histone-lysine N-methyltransferase, H3 lys... 183 1e-045
sp|O82175|SUVH5_ARATH Histone-lysine N-methyltransferase, H3 lys... 166 1e-040
sp|Q8VZ17|SUVH6_ARATH Histone-lysine N-methyltransferase, H3 lys... 154 5e-037
sp|Q9C5P1|SUVH7_ARATH Histone-lysine N-methyltransferase, H3 lys... 153 1e-036
sp|Q9T0G7|SUVH9_ARATH Probable histone-lysine N-methyltransferas... 153 1e-036
sp|O22781|SUVH2_ARATH Histone-lysine N-methyltransferase, H3 lys... 137 8e-032
sp|Q8GZB6|SUVH4_ARATH Histone-lysine N-methyltransferase, H3 lys... 125 4e-028
sp|O60016|CLR4_SCHPO Histone-lysine N-methyltransferase, H3 lysi... 109 2e-023
sp|Q9H9B1|EHMT1_HUMAN Histone-lysine N-methyltransferase, H3 lys... 107 9e-023
sp|Q96KQ7|EHMT2_HUMAN Histone-lysine N-methyltransferase, H3 lys... 102 2e-021
sp|Q5I0M0|SETMR_RAT Histone-lysine N-methyltransferase SETMAR OS... 101 6e-021
sp|Q9Z148|EHMT2_MOUSE Histone-lysine N-methyltransferase, H3 lys... 101 8e-021
sp|Q80UJ9|SETMR_MOUSE Histone-lysine N-methyltransferase SETMAR ... 100 1e-020
sp|O64827|SUVR5_ARATH Histone-lysine N-methyltransferase SUVR5 O... 99 2e-020
sp|Q0VD24|SETMR_BOVIN Histone-lysine N-methyltransferase SETMAR ... 94 6e-019
sp|Q53H47|SETMR_HUMAN Histone-lysine N-methyltransferase SETMAR ... 94 1e-018
sp|Q08BR4|STB1B_DANRE Histone-lysine N-methyltransferase SETDB1-... 93 1e-018
sp|Q3EC60|SUVHA_ARATH Putative histone-lysine N-methyltransferas... 77 1e-013
sp|Q15047|SETB1_HUMAN Histone-lysine N-methyltransferase SETDB1 ... 77 1e-013
sp|O88974|SETB1_MOUSE Histone-lysine N-methyltransferase SETDB1 ... 77 1e-013
sp|Q32KD2|SETB1_DROME Histone-lysine N-methyltransferase eggless... 75 5e-013
sp|Q28Z18|SETB1_DROPS Histone-lysine N-methyltransferase eggless... 75 5e-013
sp|Q6INA9|SETB1_XENLA Histone-lysine N-methyltransferase SETDB1 ... 74 1e-012
sp|Q6YI93|SETB2_XENLA Histone-lysine N-methyltransferase SETDB2 ... 72 2e-012
sp|Q1L8U8|STB1A_DANRE Histone-lysine N-methyltransferase SETDB1-... 69 3e-011
>sp|Q93YF5|SUVH1_TOBAC Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH1 OS=Nicotiana tabacum GN=SUVH1 PE=1 SV=1
Length = 704
Score = 354 bits (906), Expect = 5e-097
Identities = 159/247 (64%), Positives = 200/247 (80%), Gaps = 1/247 (0%)
Frame = -3
Query: 741 RLVRLPGQPEAFTVWKSIEQWKETNTTRVGLILPDLTSGAETFPVSLVNDVDGEKGPAHF 562
+L+R+PGQPEAF VWKSI+QWK+ +RVG+ILPDLTSGAE+ PV LVNDVD EKGPA+F
Sbjct: 409 KLLRVPGQPEAFKVWKSIQQWKDGVASRVGVILPDLTSGAESQPVCLVNDVDDEKGPAYF 468
Query: 561 TYIPSLKYSKPVNLTEPTAGCNCTGGCLPGNSNCPCIQKNGGYLPYTANGLLVNQKSLLH 382
TYIPSLKYSKP + P+ C+C GGC PG+SNC CIQ NGG+LPY++ G+L++ K+L+H
Sbjct: 469 TYIPSLKYSKPFVMPRPSPSCHCVGGCQPGDSNCACIQSNGGFLPYSSLGVLLSYKTLIH 528
Query: 381 ECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEALEKL 202
ECG +C+CPPNCRNR+SQGG K RLEVFKTK++GWGLRSWDPIR G FICEYAGE ++
Sbjct: 529 ECGSACSCPPNCRNRMSQGGPKARLEVFKTKNRGWGLRSWDPIRGGGFICEYAGEVID-A 587
Query: 201 GDDRADDYCFDANRTCQPLGVLPGDSNETPNVPFPLLISANTAGNVARFMNHSCSPNVFW 22
G+ D+Y FDA R PL ++E+ VPFPL+ISA GN++RFMNHSCSPNV+W
Sbjct: 588 GNYSDDNYIFDATRIYAPLEAERDYNDESRKVPFPLVISAKNGGNISRFMNHSCSPNVYW 647
Query: 21 QPILREN 1
Q ++R++
Sbjct: 648 QLVVRQS 654
>sp|Q9C5P4|SUVH3_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH3 OS=Arabidopsis thaliana GN=SUVH3 PE=2 SV=2
Length = 669
Score = 261 bits (665), Expect = 5e-069
Identities = 120/197 (60%), Positives = 150/197 (76%), Gaps = 3/197 (1%)
Frame = -3
Query: 741 RLVRLPGQPEAFTVWKSIEQWKETNTTRVGLILPDLTSGAETFPVSLVNDVDGEKGPAHF 562
+LVR PGQP AF WKS+++WKE TTR GLILPDLTSGAE+ PVSLVNDVD +KGPA+F
Sbjct: 352 KLVRQPGQPPAFGFWKSVQKWKEGLTTRPGLILPDLTSGAESKPVSLVNDVDEDKGPAYF 411
Query: 561 TYIPSLKYSKPVNLTEPTAGCNCTGGCLPGNSNCPCIQKNGGYLPYTANGLLVNQKSLLH 382
TY SLKYS+ LT+P GC+C+G C PGN NC CI+KN G LPY +LV+++ +++
Sbjct: 412 TYTSSLKYSETFKLTQPVIGCSCSGSCSPGNHNCSCIRKNDGDLPYLNGVILVSRRPVIY 471
Query: 381 ECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEALEK- 205
ECGP+C C +C+NRV Q GLK RLEVFKT+++GWGLRSWD +RAG+FICEYAGE +
Sbjct: 472 ECGPTCPCHASCKNRVIQTGLKSRLEVFKTRNRGWGLRSWDSLRAGSFICEYAGEVKDNG 531
Query: 204 --LGDDRADDYCFDANR 160
G+ D Y FD +R
Sbjct: 532 NLRGNQEEDAYVFDTSR 548
Score = 69 bits (166), Expect = 3e-011
Identities = 32/44 (72%), Positives = 35/44 (79%), Gaps = 3/44 (6%)
Frame = -3
Query: 126 SNETP---NVPFPLLISANTAGNVARFMNHSCSPNVFWQPILRE 4
S E P N+P PLLISA GNVARFMNHSCSPNVFWQP++RE
Sbjct: 567 STEVPEEFNLPSPLLISAKKFGNVARFMNHSCSPNVFWQPVIRE 610
>sp|Q9FF80|SUVH1_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH1 OS=Arabidopsis thaliana GN=SUVH1 PE=2 SV=1
Length = 670
Score = 240 bits (610), Expect = 1e-062
Identities = 110/201 (54%), Positives = 144/201 (71%), Gaps = 4/201 (1%)
Frame = -3
Query: 741 RLVRLPGQPEAFTVWKSIEQWKETNTTRVGLILPDLTSGAETFPVSLVNDVDGEKGPAHF 562
+LVR PGQP AF W +I++WK +R GLILPD+TSG E+ PVSLVN+VD + GPA+F
Sbjct: 354 KLVRAPGQPPAFASWTAIQKWKTGVPSRQGLILPDMTSGVESIPVSLVNEVDTDNGPAYF 413
Query: 561 TYIPSLKYSKPVNLTEPTAGCNCTGGCLPGNSNCPCIQKNGGYLPYTANGLLVNQKSLLH 382
TY ++KYS+ L +P+ GC+C C PGN +C CI+KNGG PYT NG+LV++K +++
Sbjct: 414 TYSTTVKYSESFKLMQPSFGCDCANLCKPGNLDCHCIRKNGGDFPYTGNGILVSRKPMIY 473
Query: 381 ECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEALEKL 202
EC PSC C C+N+V+Q G+K+RLEVFKT ++GWGLRSWD IRAG+FIC Y GEA +K
Sbjct: 474 ECSPSCPC-STCKNKVTQMGVKVRLEVFKTANRGWGLRSWDAIRAGSFICIYVGEAKDKS 532
Query: 201 GDDRA---DDYCFDANRTCQP 148
+ DDY FD P
Sbjct: 533 KVQQTMANDDYTFDTTNVYNP 553
Score = 67 bits (163), Expect = 8e-011
Identities = 28/43 (65%), Positives = 33/43 (76%)
Frame = -3
Query: 129 DSNETPNVPFPLLISANTAGNVARFMNHSCSPNVFWQPILREN 1
+ +E +P PL+ISA GNVARFMNHSCSPNVFWQP+ EN
Sbjct: 570 EMSEESEIPLPLIISAKNVGNVARFMNHSCSPNVFWQPVSYEN 612
>sp|Q9C5P0|SUVH8_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH8 OS=Arabidopsis thaliana GN=SUVH8 PE=2 SV=1
Length = 755
Score = 183 bits (463), Expect = 1e-045
Identities = 114/257 (44%), Positives = 142/257 (55%), Gaps = 24/257 (9%)
Frame = -3
Query: 741 RLVRLPGQPEAFTVWKSIEQWK--ETNTTRVGLILPDLTSGAETFPVSLVNDVDGEKG-- 574
+L+R PGQP + +WK +E + E R G IL DL+ G E V LVN+VD E
Sbjct: 445 KLLRKPGQPPGYAIWKLVENLRNHELIDPRQGFILGDLSFGEEGLRVPLVNEVDEEDKTI 504
Query: 573 PAHFTYIPSLKYSKPVNLTEPTAGCNCTGGCLPGNSNCPCIQKNGGYLPYTANGLLVNQK 394
P F YI S YS N + + NC CI KN G LPY N +LV +K
Sbjct: 505 PDDFDYIRSQCYSGMTNDVNVDSQSLVQSYI---HQNCTCILKNCGQLPYHDN-ILVCRK 560
Query: 393 SLLHECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEA 214
L++ECG SC R+ + GLK+ LEVFKT + GWGLRSWDPIRAG FICE+ G +
Sbjct: 561 PLIYECGGSCP------TRMVETGLKLHLEVFKTSNCGWGLRSWDPIRAGTFICEFTGVS 614
Query: 213 LEKLGDDRADDYCFDANRTCQPL------GVLPGDS----NETPNVPFPLLISANTAGNV 64
K + DDY FD +R +L D+ +E N+P +LISA GNV
Sbjct: 615 KTKEEVEEDDDYLFDTSRIYHSFRWNYEPELLCEDACEQVSEDANLPTQVLISAKEKGNV 674
Query: 63 ARFMNHSCSPNVFWQPI 13
RFMNH+C PNVFWQPI
Sbjct: 675 GRFMNHNCWPNVFWQPI 691
>sp|O82175|SUVH5_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH5 OS=Arabidopsis thaliana GN=SUVH5 PE=2 SV=1
Length = 794
Score = 166 bits (420), Expect = 1e-040
Identities = 92/207 (44%), Positives = 123/207 (59%), Gaps = 16/207 (7%)
Frame = -3
Query: 741 RLVRLPGQPEAFTVWKSIEQWKETNTTRVGLILPDLTSGAETFPVSLVNDVDGEKGPAHF 562
+L R+PGQPE WK + + K++ R GL D+T G ET P+ VN++D EK P F
Sbjct: 512 KLRRIPGQPE--LPWKEVAKSKKSE-FRDGLCNVDITEGKETLPICAVNNLDDEK-PPPF 567
Query: 561 TYIPSLKY---SKPVNLTEPTAGCNCTGGCLPGNSNCPCIQKNGGYLPYTANGLLVNQKS 391
Y + Y +P+ P C CT GC + NC CI KNGG +PY +G +V K
Sbjct: 568 IYTAKMIYPDWCRPI----PPKSCGCTNGC-SKSKNCACIVKNGGKIPY-YDGAIVEIKP 621
Query: 390 LLHECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEAL 211
L++ECGP C CPP+C RVSQ G+KI+LE+FKT+ +GWG+RS + I G+FICEYAGE L
Sbjct: 622 LVYECGPHCKCPPSCNMRVSQHGIKIKLEIFKTESRGWGVRSLESIPIGSFICEYAGELL 681
Query: 210 EKLGDDR---ADDYCFDANRTCQPLGV 139
E + D+Y FD P +
Sbjct: 682 EDKQAESLTGKDEYLFDLGDEDDPFTI 708
>sp|Q8VZ17|SUVH6_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH6 OS=Arabidopsis thaliana GN=SUVH6 PE=2 SV=2
Length = 790
Score = 154 bits (389), Expect = 5e-037
Identities = 86/198 (43%), Positives = 114/198 (57%), Gaps = 16/198 (8%)
Frame = -3
Query: 741 RLVRLPGQPEAFTVWKSIEQWKETNTTRVGLILPDLTSGAETFPVSLVNDVDGEKGPAHF 562
+L R+PGQPE W +E K + R GL D++ G E P+S VN++D EK P F
Sbjct: 479 QLRRIPGQPE--LSW--VEVKKSKSKYREGLCKLDISEGKEQSPISAVNEIDDEKPPL-F 533
Query: 561 TYIPSLKY---SKPVNLTEPTAGCNCTGGCLPGNSN-CPCIQKNGGYLPYTANGLLVNQK 394
TY L Y +PV P C CT C + C C++KNGG +PY +G +V K
Sbjct: 534 TYTVKLIYPDWCRPV----PPKSCCCTTRCTEAEARVCACVEKNGGEIPYNFDGAIVGAK 589
Query: 393 SLLHECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEA 214
++ECGP C CP +C RV+Q G+K+ LE+FKTK +GWG+R I G+FICEY GE
Sbjct: 590 PTIYECGPLCKCPSSCYLRVTQHGIKLPLEIFKTKSRGWGVRCLKSIPIGSFICEYVGEL 649
Query: 213 LEKLGDDRA---DDYCFD 169
LE +R D+Y FD
Sbjct: 650 LEDSEAERRIGNDEYLFD 667
>sp|Q9C5P1|SUVH7_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH7 OS=Arabidopsis thaliana GN=SUVH7 PE=2 SV=1
Length = 693
Score = 153 bits (385), Expect = 1e-036
Identities = 86/179 (48%), Positives = 110/179 (61%), Gaps = 11/179 (6%)
Frame = -3
Query: 663 TRVGLILPDLTSGAETFPVSLVNDVDGEKG--PAHFTYIPSLKYS----KPVNLTEPTAG 502
+R G IL DL+ GAE V LVN+VD + P F YIPS +S + + G
Sbjct: 398 SRQGFILEDLSFGAELLRVPLVNEVDEDDKTIPEDFDYIPSQCHSGMMTHEFHFDRQSLG 457
Query: 501 C-NCT-GGCLPGNSNCPCIQKNGGYLPYTANGLLVNQKSLLHECGPSCTCPPNCRNRVSQ 328
C NC C+ + NC C+Q+NG LPY N +LV +K L++ECG SC CP +C R+ Q
Sbjct: 458 CQNCRHQPCM--HQNCTCVQRNGDLLPY-HNNILVCRKPLIYECGGSCPCPDHCPTRLVQ 514
Query: 327 GGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEALEKLGDDRADDYCFDANRTCQ 151
GLK+ LEVFKT++ GWGLRSWDPIRAG FICE+AG K + DDY FD ++ Q
Sbjct: 515 TGLKLHLEVFKTRNCGWGLRSWDPIRAGTFICEFAGLRKTKEEVEEDDDYLFDTSKIYQ 573
>sp|Q9T0G7|SUVH9_ARATH Probable histone-lysine N-methyltransferase, H3 lysine-9
specific SUVH9 OS=Arabidopsis thaliana GN=SUVH9 PE=2 SV=1
Length = 650
Score = 153 bits (385), Expect = 1e-036
Identities = 78/181 (43%), Positives = 108/181 (59%), Gaps = 8/181 (4%)
Frame = -3
Query: 732 RLPGQPEAFTVWKSIEQWKETNTTRV---GLILPDLTSGAETFPVSLVNDVDGEKGPAHF 562
R+ GQ E + + +TN V G I D+++G E PV L ND+D ++ P ++
Sbjct: 352 RIEGQAEMGSSVLKFARTLKTNPLSVRPRGYINFDISNGKENVPVYLFNDIDSDQEPLYY 411
Query: 561 TYIPSLKYSKP--VNLTEPTAGCNCTGGCLPGNSNCPCIQKNGGYLPYTANGLLVNQKSL 388
Y+ + V + +GC+C GC S C C KN G + Y NG L+ QK L
Sbjct: 412 EYLAQTSFPPGLFVQQSGNASGCDCVNGC---GSGCLCEAKNSGEIAYDYNGTLIRQKPL 468
Query: 387 LHECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEALE 208
+HECG +C CPP+CRNRV+Q GL+ RLEVF++ + GWG+RS D + AGAFICEYAG AL
Sbjct: 469 IHECGSACQCPPSCRNRVTQKGLRNRLEVFRSLETGWGVRSLDVLHAGAFICEYAGVALT 528
Query: 207 K 205
+
Sbjct: 529 R 529
>sp|O22781|SUVH2_ARATH Histone-lysine N-methyltransferase, H3 lysine-9, H3
lysine-27, H4 lysine-20 and cytosine specific SUVH2 OS=Arabidopsis
thaliana GN=SUVH2 PE=1 SV=1
Length = 651
Score = 137 bits (344), Expect = 8e-032
Identities = 73/186 (39%), Positives = 107/186 (57%), Gaps = 14/186 (7%)
Frame = -3
Query: 735 VRLPGQPEAFTVWKSIEQWKETNTTRVGLILP------DLTSGAETFPVSLVNDVDGEKG 574
VR+ GQP + ++ ++ +T + ++ P DL++ E PV L NDVDG++
Sbjct: 353 VRIEGQP---MMGSAVMRFAQTLRNKPSMVRPTGYVSFDLSNKKENVPVFLYNDVDGDQE 409
Query: 573 PAHFTYIPSLKYSKPV--NLTEPTAGCNCTGGCLPGNSNCPCIQKNGGYLPYTANGLLVN 400
P H+ YI + + GC C C +C C +KNGG Y NG L+
Sbjct: 410 PRHYEYIAKAVFPPGIFGQGGISRTGCECKLSC---TDDCLCARKNGGEFAYDDNGHLLK 466
Query: 399 QKSLLHECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAG 220
K ++ ECG CTC P+C++RV+Q GL+ RLEVF++K+ GWG+R+ D I AGAFICEYAG
Sbjct: 467 GKHVVFECGEFCTCGPSCKSRVTQKGLRNRLEVFRSKETGWGVRTLDLIEAGAFICEYAG 526
Query: 219 EALEKL 202
+ +L
Sbjct: 527 VVVTRL 532
>sp|Q8GZB6|SUVH4_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH4 OS=Arabidopsis thaliana GN=SUVH4 PE=1 SV=2
Length = 624
Score = 125 bits (312), Expect = 4e-028
Identities = 76/204 (37%), Positives = 104/204 (50%), Gaps = 11/204 (5%)
Frame = -3
Query: 723 GQPEAFTVWKSIEQWK-ETNTTRV-GLILPDLTSGAETFPVSLVNDVDGE--KGPAHFTY 556
GQPE T + + T+T+ + GL+ D++ G E + N VD + FTY
Sbjct: 305 GQPELTTDQVNFVAGRIPTSTSEIEGLVCEDISGGLEFKGIPATNRVDDSPVSPTSGFTY 364
Query: 555 IPSLKYSKPVNLTEPTAGCNCTGGCLPGNSNCPCIQKNGGYLPYT--ANGLLVNQKSLLH 382
I SL V + + + GCNC G C + C C + NGG PY +G L+ + ++
Sbjct: 365 IKSLIIEPNVIIPKSSTGCNCRGSC-TDSKKCACAKLNGGNFPYVDLNDGRLIESRDVVF 423
Query: 381 ECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEALEKL 202
ECGP C C P C NR SQ L+ LEVF++ KGW +RSW+ I AG+ +CEY G
Sbjct: 424 ECGPHCGCGPKCVNRTSQKRLRFNLEVFRSAKKGWAVRSWEYIPAGSPVCEYIGVVRRTA 483
Query: 201 GDDRADD--YCF--DANRTCQPLG 142
D D Y F D +T Q LG
Sbjct: 484 DVDTISDNEYIFEIDCQQTMQGLG 507
>sp|O60016|CLR4_SCHPO Histone-lysine N-methyltransferase, H3 lysine-9 specific
OS=Schizosaccharomyces pombe GN=clr4 PE=1 SV=2
Length = 490
Score = 109 bits (272), Expect = 2e-023
Identities = 75/211 (35%), Positives = 108/211 (51%), Gaps = 32/211 (15%)
Frame = -3
Query: 609 VSLVNDVDGEKGPA-HFTYIPSLKYSKPVNLTEPT--AGCNCT--GGC-LPGNSNCPCIQ 448
V+LVN+VD E P+ F +I + ++ V +P +GCNC+ GGC L S C C+
Sbjct: 221 VTLVNEVDDEPCPSLDFQFISQYRLTQGVIPPDPNFQSGCNCSSLGGCDLNNPSRCECLD 280
Query: 447 --KNGGYLPYTANG-LLVNQKSLLHECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGW 277
+ Y A G + + ++++EC C+C C NRV Q G + LE+FKTK+KGW
Sbjct: 281 DLDEPTHFAYDAQGRVRADTGAVIYECNSFCSCSMECPNRVVQRGRTLPLEIFKTKEKGW 340
Query: 276 GLRSWDPIRAGAFICEYAGEAL--------EKLGDDRADDYCFDANRTCQPLGVLPGDSN 121
G+RS AG FI Y GE + +K DD Y FD + + D++
Sbjct: 341 GVRSLRFAPAGTFITCYLGEVITSAEAAKRDKNYDDDGITYLFDLD--------MFDDAS 392
Query: 120 ETPNVPFPLLISANTAGNVARFMNHSCSPNV 28
E + A G+V+RF NHSCSPN+
Sbjct: 393 E-------YTVDAQNYGDVSRFFNHSCSPNI 416
>sp|Q9H9B1|EHMT1_HUMAN Histone-lysine N-methyltransferase, H3 lysine-9 specific
5 OS=Homo sapiens GN=EHMT1 PE=1 SV=3
Length = 1267
Score = 107 bits (266), Expect = 9e-023
Identities = 61/174 (35%), Positives = 88/174 (50%), Gaps = 19/174 (10%)
Frame = -3
Query: 651 LILPDLTSGAETFPVSLVNDVDGEKGPAHFTYIPSLKYSKPVNLTEPTAG---CNCTGGC 481
++ D+ G E P+ VN VD E P+++ Y+ + P+N+ C C C
Sbjct: 978 IVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDC 1037
Query: 480 LPGNSNCPCIQ--------KNGGYLPYTANGLLVNQKSLLHECGPSCTCPPNCRNRVSQG 325
+SNC C Q K+G LP + + L+ EC +C+C NCRNRV Q
Sbjct: 1038 --SSSNCMCGQLSMRCWYDKDGRLLP----EFNMAEPPLIFECNHACSCWRNCRNRVVQN 1091
Query: 324 GLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEALEKLGDD--RADDYCFD 169
GL+ RL++++T+D GWG+RS I G F+CEY GE + D D Y FD
Sbjct: 1092 GLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVREEDSYLFD 1145
>sp|Q96KQ7|EHMT2_HUMAN Histone-lysine N-methyltransferase, H3 lysine-9 specific
3 OS=Homo sapiens GN=EHMT2 PE=1 SV=3
Length = 1210
Score = 102 bits (254), Expect = 2e-021
Identities = 62/171 (36%), Positives = 88/171 (51%), Gaps = 13/171 (7%)
Frame = -3
Query: 651 LILPDLTSGAETFPVSLVNDVDGEKGPAHFTYIPSLKYSKPVNLTEPTA---GCNCTGGC 481
+I D+ G E P+ VN VDGE P + YI + +N+ C C C
Sbjct: 921 IICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDC 980
Query: 480 LPGNSNCPCIQKNGGYLPYTANGLLVN-----QKSLLHECGPSCTCPPNCRNRVSQGGLK 316
+SNC C Q + Y +G L+ + L+ EC +C+C NC+NRV Q G+K
Sbjct: 981 --SSSNCLCGQLSIRCW-YDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIK 1037
Query: 315 IRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEAL-EKLGDDRADD-YCFD 169
+RL++++T GWG+R+ I G FICEY GE + + D R DD Y FD
Sbjct: 1038 VRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFD 1088
>sp|Q5I0M0|SETMR_RAT Histone-lysine N-methyltransferase SETMAR OS=Rattus
norvegicus GN=Setmar PE=2 SV=1
Length = 315
Score = 101 bits (250), Expect = 6e-021
Identities = 71/217 (32%), Positives = 96/217 (44%), Gaps = 16/217 (7%)
Frame = -3
Query: 639 DLTSGAETFPVSLVNDVDGEKGPAHFTYIPSLKYSKPVNLTEPT----AGCNC-TGGCLP 475
D+ G E PVSL G + P F Y P V++ +PT GC C C+P
Sbjct: 28 DVACGLENLPVSLWPLGAGPR-PKPFQYTPDHVAGPGVDM-DPTQITFPGCACIKTPCVP 85
Query: 474 GNSNCPCIQKNGGY---LPYTANGLLVNQKSLLHECGPSCTCPPNCRNRVSQGGLKIRLE 304
G C C++ Y L G + EC C C +CRNRV Q GL+ L+
Sbjct: 86 G--TCSCLRHESNYNDNLCLRDVGSEAKYAKPVFECNVLCQCGEHCRNRVVQSGLQFLLQ 143
Query: 303 VFKTKDKGWGLRSWDPIRAGAFICEYAGEALEKLGDDRADDYCFDANRTCQPLGVLPGDS 124
VF+T+ KGWGLR+ + I G F+CEYAGE L R P ++
Sbjct: 144 VFQTEKKGWGLRTLEYIPKGRFVCEYAGEVLGFSEVQRR----IHLQTAHDPNYIIALRE 199
Query: 123 NETPNVPFPLLISANTAGNVARFMNHSCSPNVFWQPI 13
+ + GN+ RF+NHSC PN+ P+
Sbjct: 200 HTYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPV 236
>sp|Q9Z148|EHMT2_MOUSE Histone-lysine N-methyltransferase, H3 lysine-9 specific
3 OS=Mus musculus GN=Ehmt2 PE=1 SV=2
Length = 1263
Score = 101 bits (249), Expect = 8e-021
Identities = 61/171 (35%), Positives = 88/171 (51%), Gaps = 13/171 (7%)
Frame = -3
Query: 651 LILPDLTSGAETFPVSLVNDVDGEKGPAHFTYIPSLKYSKPVNLTEPTA---GCNCTGGC 481
+I D+ G E P+ VN VDGE P + YI + +N+ C C C
Sbjct: 974 IICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDC 1033
Query: 480 LPGNSNCPCIQKNGGYLPYTANGLLVN-----QKSLLHECGPSCTCPPNCRNRVSQGGLK 316
+SNC C Q + Y +G L+ + L+ EC +C+C +C+NRV Q G+K
Sbjct: 1034 --SSSNCLCGQLSIRCW-YDKDGRLLQEFNKIEPPLIFECNQACSCWRSCKNRVVQSGIK 1090
Query: 315 IRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEAL-EKLGDDRADD-YCFD 169
+RL++++T GWG+R+ I G FICEY GE + + D R DD Y FD
Sbjct: 1091 VRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFD 1141
>sp|Q80UJ9|SETMR_MOUSE Histone-lysine N-methyltransferase SETMAR OS=Mus musculus
GN=Setmar PE=2 SV=1
Length = 309
Score = 100 bits (248), Expect = 1e-020
Identities = 74/226 (32%), Positives = 95/226 (42%), Gaps = 34/226 (15%)
Frame = -3
Query: 639 DLTSGAETFPVSLVNDVDGEKGPAHFTYIPSLKYS-----KPVNLTEPTAGCNC-TGGCL 478
D+ G E PVSL + E P F Y P P +T P GC C C+
Sbjct: 28 DVACGLENLPVSLW-PLGAEPRPKPFQYTPDHVAGPGADIDPTQITFP--GCACIETPCV 84
Query: 477 PGNSNCPCIQKNGGY---LPYTANGLLVNQKSLLHECGPSCTCPPNCRNRVSQGGLKIRL 307
PG C C++ Y L + G + EC C C CRNRV Q GL L
Sbjct: 85 PG--TCSCLRHENNYDDNLCFRDVGSEGKYAKPVFECNVLCQCGMRCRNRVVQNGLHFLL 142
Query: 306 EVFKTKDKGWGLRSWDPIRAGAFICEYAGEALE--------KLGDDRADDYCFDANRTCQ 151
+VF+T+ KGWGLR+ + I G F+CEYAGE L L +Y
Sbjct: 143 QVFQTEKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTSHDSNYIIAVRE--- 199
Query: 150 PLGVLPGDSNETPNVPFPLLISANTAGNVARFMNHSCSPNVFWQPI 13
+ G ET + GN+ RF+NHSC PN+ P+
Sbjct: 200 --HIYSGQIMET-------FVDPTYIGNIGRFLNHSCEPNLLMIPV 236
>sp|O64827|SUVR5_ARATH Histone-lysine N-methyltransferase SUVR5 OS=Arabidopsis
thaliana GN=SUVR5 PE=1 SV=2
Length = 1114
Score = 99 bits (246), Expect = 2e-020
Identities = 52/148 (35%), Positives = 83/148 (56%), Gaps = 8/148 (5%)
Frame = -3
Query: 429 PYTANGLLVNQKSL-LHECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPI 253
PY ++ ++ ++EC C C C+NRV Q G++ +LEVF+T+ KGWGLR+ + I
Sbjct: 917 PYDGKQRIILEEGYPVYECNKFCGCSRTCQNRVLQNGIRAKLEVFRTESKGWGLRACEHI 976
Query: 252 RAGAFICEYAGEALEKL-GDDRADDYCFDANRTCQPLGVLPGDSNETPNV---PFPLLIS 85
G F+CEY GE L++ + R + Y N C + + + N+ + I
Sbjct: 977 LRGTFVCEYIGEVLDQQEANKRRNQY---GNGDCSYILDIDANINDIGRLMEEELDYAID 1033
Query: 84 ANTAGNVARFMNHSCSPNVFWQPILREN 1
A T GN++RF+NHSCSPN+ ++ E+
Sbjct: 1034 ATTHGNISRFINHSCSPNLVNHQVIVES 1061
>sp|Q0VD24|SETMR_BOVIN Histone-lysine N-methyltransferase SETMAR OS=Bos taurus
GN=SETMAR PE=2 SV=1
Length = 306
Score = 94 bits (233), Expect = 6e-019
Identities = 66/180 (36%), Positives = 82/180 (45%), Gaps = 18/180 (10%)
Frame = -3
Query: 531 PVNLTEPTAGCNC-TGGCLPGNSNCPCIQKNGGYLPYTA---NGLLVNQKSLLHECGPSC 364
P +T P GC C CLPG C C++ Y + G + EC C
Sbjct: 54 PSQITFP--GCACLKTPCLPG--TCSCLRHENNYDDRSCLRDIGSEAKCTEPVFECNVLC 109
Query: 363 TCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEALEKLGDDRAD 184
C CRNRV Q GL+ L+VFKT KGWGLR+ D I G F+CEYAGE L R
Sbjct: 110 QCSERCRNRVVQWGLQFHLQVFKTDHKGWGLRTLDFIPKGRFVCEYAGEVLGISEVQRRV 169
Query: 183 DY--CFDANRTCQ-PLGVLPGDSNETPNVPFPLLISANTAGNVARFMNHSCSPNVFWQPI 13
D+N V G ET + + GN+ RF+NHSC PN+ P+
Sbjct: 170 QLQTIHDSNYIIAIREHVYNGQVMET-------FVDPASIGNIGRFLNHSCEPNLLMIPV 222
>sp|Q53H47|SETMR_HUMAN Histone-lysine N-methyltransferase SETMAR OS=Homo sapiens
GN=SETMAR PE=1 SV=1
Length = 671
Score = 94 bits (231), Expect = 1e-018
Identities = 75/225 (33%), Positives = 93/225 (41%), Gaps = 34/225 (15%)
Frame = -3
Query: 639 DLTSGAETFPVSLVNDVDGEKGPAHFTYIPSLKYS-----KPVNLTEPTAGCNCT-GGCL 478
D+ G E PV PA F Y P P +T P GC C CL
Sbjct: 16 DVACGQENLPVGA---WPPGAAPAPFQYTPDHVVGPGADIDPTQITFP--GCICVKTPCL 70
Query: 477 PGNSNCPCIQKNGGYLPYTA---NGLLVNQKSLLHECGPSCTCPPNCRNRVSQGGLKIRL 307
PG C C++ Y + G + EC C C +CRNRV Q GL+
Sbjct: 71 PG--TCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNVLCRCSDHCRNRVVQKGLQFHF 128
Query: 306 EVFKTKDKGWGLRSWDPIRAGAFICEYAGEALEKLGDDR-------ADDYCFDANRTCQP 148
+VFKT KGWGLR+ + I G F+CEYAGE L R +D A R
Sbjct: 129 QVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIRE--- 185
Query: 147 LGVLPGDSNETPNVPFPLLISANTAGNVARFMNHSCSPNVFWQPI 13
V G ET + GN+ RF+NHSC PN+ P+
Sbjct: 186 -HVYNGQVMET-------FVDPTYIGNIGRFLNHSCEPNLLMIPV 222
>sp|Q08BR4|STB1B_DANRE Histone-lysine N-methyltransferase SETDB1-B OS=Danio
rerio GN=setdb1b PE=2 SV=2
Length = 1216
Score = 93 bits (230), Expect = 1e-018
Identities = 64/184 (34%), Positives = 91/184 (49%), Gaps = 41/184 (22%)
Frame = -3
Query: 639 DLTSGAETFPVSLVNDVDGEKGPAHFTYIPSLKYSKP--------VNLT-EPTAGCNCTG 487
D+TSG E P+S VN++D T PS+ YSK +N + + GC+CT
Sbjct: 682 DITSGREDIPLSCVNEIDN-------TPPPSVAYSKERIPEDGVYINTSADFLVGCDCTD 734
Query: 486 GCLPGNSNCPC---------------IQKNGGYLPYTANGLLVNQKSLLHECGPSCTCPP 352
GC S C C I N GY + L + ++EC C C
Sbjct: 735 GC-RDKSKCSCHQLTLQATGCTPGGQINPNAGYHYKRLDECL---PTGIYECNKRCRCNM 790
Query: 351 N-CRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEAL-----EKLGDDR 190
C NR+ Q GL++RL++FKT++KGWG+R D I G+F+C YAG+ L +K G +
Sbjct: 791 QMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEM 850
Query: 189 ADDY 178
D+Y
Sbjct: 851 GDEY 854
>sp|Q3EC60|SUVHA_ARATH Putative histone-lysine N-methyltransferase, H3 lysine-9
specific SUVH10 OS=Arabidopsis thaliana GN=SUVH10 PE=3 SV=1
Length = 312
Score = 77 bits (188), Expect = 1e-013
Identities = 39/83 (46%), Positives = 50/83 (60%)
Frame = -3
Query: 741 RLVRLPGQPEAFTVWKSIEQWKETNTTRVGLILPDLTSGAETFPVSLVNDVDGEKGPAHF 562
+LVR P Q AF +WKSI+ W+ + R GLIL DL++GAE V LVN+VD E GPA F
Sbjct: 129 KLVREPDQKPAFGIWKSIQNWRNGLSIRPGLILEDLSNGAENLKVCLVNEVDKENGPALF 188
Query: 561 TYIPSLKYSKPVNLTEPTAGCNC 493
Y+ SL + N+ C C
Sbjct: 189 RYVTSLIHEVINNIPSMVDRCAC 211
>sp|Q15047|SETB1_HUMAN Histone-lysine N-methyltransferase SETDB1 OS=Homo sapiens
GN=SETDB1 PE=1 SV=1
Length = 1291
Score = 77 bits (187), Expect = 1e-013
Identities = 43/108 (39%), Positives = 60/108 (55%), Gaps = 13/108 (12%)
Frame = -3
Query: 483 CLPGNSNCPCIQKNGGYLPYTANGLLVNQKSLLHECGPSCTCPPN-CRNRVSQGGLKIRL 307
C PG I N GY L + ++EC C C PN C NR+ Q GL++RL
Sbjct: 753 CTPGGQ----INPNSGYQYKRLEECL---PTGVYECNKRCKCDPNMCTNRLVQHGLQVRL 805
Query: 306 EVFKTKDKGWGLRSWDPIRAGAFICEYAGEAL-----EKLGDDRADDY 178
++FKT++KGWG+R D I G+F+C YAG+ L +K G + D+Y
Sbjct: 806 QLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEY 853
>sp|O88974|SETB1_MOUSE Histone-lysine N-methyltransferase SETDB1 OS=Mus musculus
GN=Setdb1 PE=1 SV=1
Length = 1307
Score = 77 bits (187), Expect = 1e-013
Identities = 42/108 (38%), Positives = 60/108 (55%), Gaps = 13/108 (12%)
Frame = -3
Query: 483 CLPGNSNCPCIQKNGGYLPYTANGLLVNQKSLLHECGPSCTCPPN-CRNRVSQGGLKIRL 307
C PG + N GY L + ++EC C C PN C NR+ Q GL++RL
Sbjct: 770 CTPGGQ----VNPNSGYQYKRLEECL---PTGVYECNKRCNCDPNMCTNRLVQHGLQVRL 822
Query: 306 EVFKTKDKGWGLRSWDPIRAGAFICEYAGEAL-----EKLGDDRADDY 178
++FKT++KGWG+R D I G+F+C YAG+ L +K G + D+Y
Sbjct: 823 QLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEY 870
>sp|Q32KD2|SETB1_DROME Histone-lysine N-methyltransferase eggless OS=Drosophila
melanogaster GN=egg PE=1 SV=1
Length = 1262
Score = 75 bits (182), Expect = 5e-013
Identities = 36/78 (46%), Positives = 47/78 (60%), Gaps = 5/78 (6%)
Frame = -3
Query: 387 LHECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEALE 208
++EC C C NC NRV Q L+++L+VFKT ++GWGLR + I GAFIC YAG L
Sbjct: 997 IYECNSRCKCKKNCLNRVVQFSLEMKLQVFKTSNRGWGLRCVNDIPKGAFICIYAGHLLT 1056
Query: 207 KL-----GDDRADDYCFD 169
+ G D D+Y D
Sbjct: 1057 ETMANEGGQDAGDEYFAD 1074
>sp|Q28Z18|SETB1_DROPS Histone-lysine N-methyltransferase eggless OS=Drosophila
pseudoobscura pseudoobscura GN=egg PE=3 SV=1
Length = 1314
Score = 75 bits (182), Expect = 5e-013
Identities = 35/78 (44%), Positives = 47/78 (60%), Gaps = 5/78 (6%)
Frame = -3
Query: 387 LHECGPSCTCPPNCRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEALE 208
++EC C C NC NRV Q L+++L+VFKT ++GWGLR + I GAF+C YAG L
Sbjct: 1050 IYECNSRCKCKKNCLNRVVQHSLEMKLQVFKTSNRGWGLRCVNDIPKGAFVCIYAGHLLT 1109
Query: 207 KL-----GDDRADDYCFD 169
+ G D D+Y D
Sbjct: 1110 EAKANEGGQDAGDEYFAD 1127
>sp|Q6INA9|SETB1_XENLA Histone-lysine N-methyltransferase SETDB1 OS=Xenopus
laevis GN=setdb1 PE=2 SV=1
Length = 1269
Score = 74 bits (179), Expect = 1e-012
Identities = 34/76 (44%), Positives = 50/76 (65%), Gaps = 6/76 (7%)
Frame = -3
Query: 387 LHECGPSCTCPPN-CRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEAL 211
++EC C C N C NR+ Q GL++RL++FKT++KGWG+R D I G+F+C YAG+ L
Sbjct: 804 VYECNKRCKCSANMCNNRLVQHGLQVRLQLFKTQNKGWGIRGLDDIAKGSFVCIYAGKIL 863
Query: 210 -----EKLGDDRADDY 178
+K G + D+Y
Sbjct: 864 TDDFADKEGLEMGDEY 879
>sp|Q6YI93|SETB2_XENLA Histone-lysine N-methyltransferase SETDB2 OS=Xenopus
laevis GN=setdb2 PE=2 SV=1
Length = 699
Score = 72 bits (176), Expect = 2e-012
Identities = 34/65 (52%), Positives = 42/65 (64%), Gaps = 1/65 (1%)
Frame = -3
Query: 387 LHECGPSCTCPPN-CRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIRAGAFICEYAGEAL 211
L+EC SC C C+NRV Q GLK+RL+VFKT KGWG+R D + G F+C YAG L
Sbjct: 362 LYECNVSCKCDRMLCQNRVVQHGLKLRLQVFKTNTKGWGVRCLDDVDKGTFVCIYAGRIL 421
Query: 210 EKLGD 196
+ D
Sbjct: 422 IRTAD 426
>sp|Q1L8U8|STB1A_DANRE Histone-lysine N-methyltransferase SETDB1-A OS=Danio
rerio GN=setdb1a PE=2 SV=1
Length = 1436
Score = 69 bits (166), Expect = 3e-011
Identities = 31/81 (38%), Positives = 50/81 (61%), Gaps = 3/81 (3%)
Frame = -3
Query: 426 YTANGLLVNQKSLLHECGPSCTCPPN-CRNRVSQGGLKIRLEVFKTKDKGWGLRSWDPIR 250
YT L + + ++EC P C C P C NR+ Q G+++RLE+F T+ KGWG+R D +
Sbjct: 1113 YTHKRLPTSLPTGVYECNPLCRCDPRMCSNRLVQHGMQLRLELFMTQHKGWGIRCKDDVP 1172
Query: 249 AGAFICEYAGEAL--EKLGDD 193
G F+C + G+ + +K+ +D
Sbjct: 1173 KGTFVCVFTGKIVNEDKMNED 1193
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,407,642,047
Number of Sequences: 462764
Number of Extensions: 3407642047
Number of Successful Extensions: 34563130
Number of sequences better than 0.0: 0
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