BLASTX 7.6.2
Query= RU02089 /QuerySize=2299
(2298 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q797A7|YFNA_BACSU Uncharacterized amino acid permease yfnA OS... 295 1e-078
sp|Q8BXR1|S7A14_MOUSE Probable cationic amino acid transporter O... 289 1e-076
sp|Q8BLQ7|CTR4_MOUSE Cationic amino acid transporter 4 OS=Mus mu... 287 2e-076
sp|O43246|CTR4_HUMAN Cationic amino acid transporter 4 OS=Homo s... 285 1e-075
sp|Q8TBB6|S7A14_HUMAN Probable cationic amino acid transporter O... 284 2e-075
sp|A0JNI9|S7A14_BOVIN Probable cationic amino acid transporter O... 282 7e-075
sp|O07576|YHDG_BACSU Uncharacterized amino acid permease yhdG OS... 248 1e-064
sp|P30825|CTR1_HUMAN High affinity cationic amino acid transport... 182 1e-044
sp|Q09143|CTR1_MOUSE High affinity cationic amino acid transport... 179 6e-044
sp|P30823|CTR1_RAT High affinity cationic amino acid transporter... 179 1e-043
sp|O08812|CTR3_RAT Cationic amino acid transporter 3 OS=Rattus n... 174 3e-042
sp|Q8WY07|CTR3_HUMAN Cationic amino acid transporter 3 OS=Homo s... 171 2e-041
sp|P52569|CTR2_HUMAN Low affinity cationic amino acid transporte... 171 3e-041
sp|P70423|CTR3_MOUSE Cationic amino acid transporter 3 OS=Mus mu... 169 1e-040
sp|P18581|CTR2_MOUSE Low affinity cationic amino acid transporte... 165 1e-039
sp|P63349|Y1999_MYCTU Uncharacterized transporter Rv1999c/MT2055... 97 5e-019
sp|P63350|Y2022_MYCBO Uncharacterized transporter Mb2022c OS=Myc... 97 5e-019
>sp|Q797A7|YFNA_BACSU Uncharacterized amino acid permease yfnA OS=Bacillus
subtilis GN=yfnA PE=3 SV=1
Length = 461
Score = 295 bits (753), Expect = 1e-078
Identities = 152/407 (37%), Positives = 254/407 (62%), Gaps = 8/407 (1%)
Frame = -3
Query: 2092 NSLIRRKQVDSVHRKAHHQ-LARELTVPHLVAIGVGSTIGAGVYILVGTVAREHSGPALT 1916
+SL R+K ++++ ++ + LAR L+ L +G+G IG G++++ GTVA +GPAL
Sbjct: 2 SSLFRKKPLETLSAQSKSKSLARTLSAFDLTLLGIGCVIGTGIFVITGTVAATGAGPALI 61
Query: 1915 ISFLIAGIAAALSAFCYAELASRCPSAGSAYHYTYICIGEGVAWLVGWALILEYTIGGSA 1736
ISF++AG+A AL+AFCYAE +S P +GS Y Y+Y+ +GE +A+L+GW L+LEY I SA
Sbjct: 62 ISFILAGLACALAAFCYAEFSSSIPISGSVYSYSYVTLGELLAFLIGWDLMLEYVIALSA 121
Query: 1735 VARGISPNLALLFGGAD-SLPVFLARQYIPALDIMVDPCAAILVFIVTGLLCVGIKESTV 1559
VA G S L G + +P L + + AA+++ ++T ++ G+KEST
Sbjct: 122 VATGWSSYFQSLLAGFNLHIPAALTGAPGSMAGAVFNLPAAVIILLITAIVSRGVKESTR 181
Query: 1558 AQGIATIANVCAMLFVIVAGTYLGFKTGWSGYQLPTGYFPFGVNGMLAGSATVFFAYIGF 1379
+ + + +L I+ G WS + PFG+ G++ +ATVFFAY+GF
Sbjct: 182 FNNVIVLMKIAIILLFIIVGIGYVKPDNWS------PFMPFGMKGVILSAATVFFAYLGF 235
Query: 1378 DSVASTAEEVKNPQRDLPLGIGAALSICCALYMLVSMVIVGLVPYHAMDPDTPISTAFAS 1199
D+V++ +EEVKNPQ+++P+GI +AL++C LY+ VS+V+ G++PY ++ P+S A
Sbjct: 236 DAVSNASEEVKNPQKNMPVGIISALAVCTVLYIAVSLVLTGMMPYAKLNVGDPVSFALKF 295
Query: 1198 HGMQWAAYIITVGAVTALCSTLMGSILPQPRILMAMARDGLLPPFFSEINKSTQVPVKSX 1019
G A II+VGA+ + + ++ + Q R+ AM+RDGLLP F++++ S + P ++
Sbjct: 296 VGQDAVAGIISVGAIIGITTVMLALLYAQVRLTFAMSRDGLLPGLFAKVHPSFKTPFRNT 355
Query: 1018 XXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMVAISVLILRYVPPD 878
+A F+++ LA +V++GTL AFT+++I+V++LR P+
Sbjct: 356 WLTGIVAAGIAGFINLGTLAHLVNMGTLAAFTVISIAVIVLRKKHPE 402
>sp|Q8BXR1|S7A14_MOUSE Probable cationic amino acid transporter OS=Mus musculus
GN=Slc7a14 PE=2 SV=1
Length = 771
Score = 289 bits (737), Expect = 1e-076
Identities = 163/477 (34%), Positives = 265/477 (55%), Gaps = 24/477 (5%)
Frame = -3
Query: 2122 QWXXXXXXXRNSLIRRKQVDSV-----HRKAH-HQLARELTVPHLVAIGVGSTIGAGVYI 1961
QW + ++R K V+S+ AH +LA+ LT L+++GVGS +G G+Y+
Sbjct: 14 QWGAAWYAMHSRILRTKPVESMLEGTGTTSAHGTKLAQVLTTVDLISLGVGSCVGTGMYV 73
Query: 1960 LVGTVAREHSGPALTISFLIAGIAAALSAFCYAELASRCP-SAGSAYHYTYICIGEGVAW 1784
+ G VA+E +GP + +SF+IA +A+ LS CYAE R P + GSAY Y+Y+ +GE VA+
Sbjct: 74 VSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAF 133
Query: 1783 LVGWALILEYTIGGSAVARGISPNLALLFGGADSLPVFLARQYIPAL----DIMVDPCAA 1616
+GW LILEY IG +A A +S L + S + + L + D A
Sbjct: 134 FIGWNLILEYLIGTAAGASALSSMFDSLANHSISRWMVDTVGTLNGLGKGEESYPDLLAL 193
Query: 1615 ILVFIVTGLLCVGIKESTVAQGIATIANVCAMLFVIVAGTYLGFKTGWSGYQLPTGYFPF 1436
++ IVT ++ +G+K S + + N+ +F+++AG + W+ Q + P
Sbjct: 194 VIAVIVTIIVALGVKNSVGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQ----FLPH 249
Query: 1435 GVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLVSMVIVG 1256
G +G+L G+AT F+A+IGFD +A+T EE KNP +P I A+L IC Y+ VSM++
Sbjct: 250 GWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSMILTL 309
Query: 1255 LVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILMAMARDGL 1076
+VPY+A+D ++P+ F +HG A +++ +G+V L +L+GS+ P PR++ AMA DGL
Sbjct: 310 MVPYYAIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGL 369
Query: 1075 LPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMVAISVLIL 896
L F + ++ T+ PV + L+ + + L M+S+GTL+A+T+V++ VL+L
Sbjct: 370 LFRFLAHVSSYTETPVVACIVSGFLAALLSLLVSLRDLIEMMSIGTLLAYTLVSVCVLLL 429
Query: 895 RYVPPDEVPLPASLQDSIDSVSLRHGSNSQDISGDDPK---GSVGSSKDISKPLLDT 734
RY P ++ + +S H + I D K V ++ S P +T
Sbjct: 430 RYQPESDI------DGFVKFLSEEHTKKKEGILADCEKETCSPVSEGEEFSSPATNT 480
>sp|Q8BLQ7|CTR4_MOUSE Cationic amino acid transporter 4 OS=Mus musculus
GN=Slc7a4 PE=1 SV=1
Length = 635
Score = 287 bits (734), Expect = 2e-076
Identities = 152/397 (38%), Positives = 241/397 (60%), Gaps = 6/397 (1%)
Frame = -3
Query: 2035 LARELTVPHLVAIGVGSTIGAGVYILVGTVAREHSGPALTISFLIAGIAAALSAFCYAEL 1856
L R L+ L +GVG +G+G+Y+L GTVA++ +GPA+ +SFL+A +A+ L+A CYAE
Sbjct: 33 LRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEF 92
Query: 1855 ASRCPSAGSAYHYTYICIGEGVAWLVGWALILEYTIGGSAVARGISPNLALLFGGA--DS 1682
+R P GSAY +TY+ +GE A+L+GW ++LEY IGG+AVAR S L +F + +
Sbjct: 93 GARVPRTGSAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNF 152
Query: 1681 LPVFLARQYIPALDIMVDPCAAILVFIVTGLLCVGIKESTVAQGIATIANVCAMLFVIVA 1502
L +P L D AA ++ + + + G + S+ + ++ +LF+IV
Sbjct: 153 TESHLGVWQVPFLAHYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVL 212
Query: 1501 GTYLGFKTGWSGYQLPTGYFPFGVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPL 1322
G L WS + G+ PFG +G+LAG+AT F+A++GFD +A+++EE KNP+ +P+
Sbjct: 213 GFILARPHNWSAEE--GGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPM 270
Query: 1321 GIGAALSICCALYMLVSMVIVGLVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALC 1142
I +LS+ Y+LVS V+ +VP+H++DPD+ ++ AF G WA +I+ VG++ A+
Sbjct: 271 AIAISLSLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYSWAGFIVAVGSICAMN 330
Query: 1141 STLMGSILPQPRILMAMARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQL 962
+ L+ ++ PRI+ AMA DGL F+ ++ TQVPV LA +D+ L
Sbjct: 331 TVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLLDLEAL 390
Query: 961 AGMVSVGTLVAFTMVAISVLILRY--VPPDEVPLPAS 857
+S+GTL+A+T VA S+++LR+ P P AS
Sbjct: 391 VQFLSIGTLLAYTFVATSIIVLRFQKASPPSSPCLAS 427
>sp|O43246|CTR4_HUMAN Cationic amino acid transporter 4 OS=Homo sapiens
GN=SLC7A4 PE=2 SV=3
Length = 635
Score = 285 bits (727), Expect = 1e-075
Identities = 147/397 (37%), Positives = 240/397 (60%), Gaps = 6/397 (1%)
Frame = -3
Query: 2035 LARELTVPHLVAIGVGSTIGAGVYILVGTVAREHSGPALTISFLIAGIAAALSAFCYAEL 1856
L R L+ L +GVG +G+G+Y+L G VA+E +GPA+ +SF +A +A+ L+A CYAE
Sbjct: 33 LRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGVAAVASLLAALCYAEF 92
Query: 1855 ASRCPSAGSAYHYTYICIGEGVAWLVGWALILEYTIGGSAVARGISPNLALLFGGA--DS 1682
+R P GSAY +TY+ +GE A+L+GW ++LEY IGG+AVAR S L +F + +
Sbjct: 93 GARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMFSHSIRNF 152
Query: 1681 LPVFLARQYIPALDIMVDPCAAILVFIVTGLLCVGIKESTVAQGIATIANVCAMLFVIVA 1502
+ +P L D AA ++ + + + G + S+ + ++ +LF+++
Sbjct: 153 TETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILFIVIL 212
Query: 1501 GTYLGFKTGWSGYQLPTGYFPFGVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPL 1322
G L WS + G+ PFG +G++AG+A+ F+A++GFD +A+++EE +NP+R +PL
Sbjct: 213 GFILAQPHNWSADE--GGFAPFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPL 270
Query: 1321 GIGAALSICCALYMLVSMVIVGLVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALC 1142
I +L+I Y+LVS V+ +VP+H++DPD+ ++ AF G +WA +I+ G++ A+
Sbjct: 271 AIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMN 330
Query: 1141 STLMGSILPQPRILMAMARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQL 962
+ L+ + PRI+ AMA DGL F+ ++ TQVPV LA +D+ L
Sbjct: 331 TVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESL 390
Query: 961 AGMVSVGTLVAFTMVAISVLILRY--VPPDEVPLPAS 857
+S+GTL+A+T VA S+++LR+ P P PAS
Sbjct: 391 VQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGPAS 427
>sp|Q8TBB6|S7A14_HUMAN Probable cationic amino acid transporter OS=Homo sapiens
GN=SLC7A14 PE=2 SV=2
Length = 771
Score = 284 bits (725), Expect = 2e-075
Identities = 166/490 (33%), Positives = 266/490 (54%), Gaps = 28/490 (5%)
Frame = -3
Query: 2155 GFDSQSPDGAKQWXXXXXXXRNSLIRRKQVDSV-----HRKAH-HQLARELTVPHLVAIG 1994
GF + QW + ++R K V+S+ AH +LA+ LT L+++G
Sbjct: 3 GFFTSLDPRRVQWGAAWYAMHSRILRTKPVESMLEGTGTTTAHGTKLAQVLTTVDLISLG 62
Query: 1993 VGSTIGAGVYILVGTVAREHSGPALTISFLIAGIAAALSAFCYAELASRCP-SAGSAYHY 1817
VGS +G G+Y++ G VA+E +GP + +SF+IA +A+ LS CYAE R P + GSAY Y
Sbjct: 63 VGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTY 122
Query: 1816 TYICIGEGVAWLVGWALILEYTIGGSAVARGIS------PNLALLFGGADSLPVFLARQY 1655
+Y+ +GE VA+ +GW LILEY IG +A A +S N + ADS V
Sbjct: 123 SYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADS--VGTLNGL 180
Query: 1654 IPALDIMVDPCAAILVFIVTGLLCVGIKESTVAQGIATIANVCAMLFVIVAGTYLGFKTG 1475
+ D A ++ IVT ++ +G+K S + + N+ +F+++AG +
Sbjct: 181 GKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKY 240
Query: 1474 WSGYQLPTGYFPFGVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSIC 1295
W+ Q + P G +G+L G+AT F+A+IGFD +A+T EE KNP +P I A+L IC
Sbjct: 241 WAEGQ----FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVIC 296
Query: 1294 CALYMLVSMVIVGLVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILP 1115
Y+ VS+++ +VPY+ +D ++P+ F +HG A +++ +G+V L +L+GS+ P
Sbjct: 297 LTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFP 356
Query: 1114 QPRILMAMARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTL 935
PR++ AMA DGLL F + ++ T+ PV + LA + + L M+S+GTL
Sbjct: 357 MPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTL 416
Query: 934 VAFTMVAISVLILRYVPPDEVPLPASLQDSIDSVSLRHGSNSQDISGDDPK---GSVGSS 764
+A+T+V++ VL+LRY P ++ + +S H + I D K V
Sbjct: 417 LAYTLVSVCVLLLRYQPESDI------DGFVKFLSEEHTKKKEGILADCEKEACSPVSEG 470
Query: 763 KDISKPLLDT 734
+ S P +T
Sbjct: 471 DEFSGPATNT 480
>sp|A0JNI9|S7A14_BOVIN Probable cationic amino acid transporter OS=Bos taurus
GN=SLC7A14 PE=2 SV=1
Length = 771
Score = 282 bits (721), Expect = 7e-075
Identities = 161/477 (33%), Positives = 262/477 (54%), Gaps = 24/477 (5%)
Frame = -3
Query: 2122 QWXXXXXXXRNSLIRRKQVDSV-----HRKAH-HQLARELTVPHLVAIGVGSTIGAGVYI 1961
QW + ++R K V+S+ AH +LA+ LT L+++GVGS +G G+Y+
Sbjct: 14 QWGAAWYAMHSRILRTKPVESMLEGTGATTAHGTKLAQVLTTMDLISLGVGSCVGTGMYV 73
Query: 1960 LVGTVAREHSGPALTISFLIAGIAAALSAFCYAELASRCP-SAGSAYHYTYICIGEGVAW 1784
+ G VA+E +GP + +SF+IA +A+ LS CYAE R P + GSAY Y+Y+ +GE VA+
Sbjct: 74 VSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAF 133
Query: 1783 LVGWALILEYTIGGSAVARGISPNLALLFGGADSLPVFLARQYIPAL----DIMVDPCAA 1616
+GW LILEY IG +A A +S L S + + + L D A
Sbjct: 134 FIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMVDSVGTLNGLGKGEQSYPDLLAL 193
Query: 1615 ILVFIVTGLLCVGIKESTVAQGIATIANVCAMLFVIVAGTYLGFKTGWSGYQLPTGYFPF 1436
++ IVT ++ +G+K S + + N+ +F+++AG + W+ Q + P+
Sbjct: 194 VIAIIVTIIVALGVKNSVGFNNVLNVLNLAVWVFIMIAGFFFINGKYWAEGQ----FLPY 249
Query: 1435 GVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLVSMVIVG 1256
G +G+L G+AT F+A+IGFD +A+T EE KNP +P I A+L IC Y+ VSM++
Sbjct: 250 GWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSMILTL 309
Query: 1255 LVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILMAMARDGL 1076
+VPY +D ++P+ F + G A +++ +G+V L +L+GS+ P PR++ AMA DGL
Sbjct: 310 MVPYDTIDTESPLMEMFVARGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGL 369
Query: 1075 LPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMVAISVLIL 896
L F + ++ T+ PV + L+ + + L M+S+GTL+A+T+V++ VL+L
Sbjct: 370 LFRFLAHVSSYTETPVVACIVSGFLAALLSLLVSLRDLIEMMSIGTLLAYTLVSVCVLLL 429
Query: 895 RYVPPDEVPLPASLQDSIDSVSLRHGSNSQDISGDDPK---GSVGSSKDISKPLLDT 734
RY P ++ + +S H + I D K V ++ S P +T
Sbjct: 430 RYQPESDI------DGFVKFLSEEHTKKKEGILADCEKEVCSPVSEGEEFSGPATNT 480
>sp|O07576|YHDG_BACSU Uncharacterized amino acid permease yhdG OS=Bacillus
subtilis GN=yhdG PE=2 SV=1
Length = 465
Score = 248 bits (633), Expect = 1e-064
Identities = 148/413 (35%), Positives = 230/413 (55%), Gaps = 15/413 (3%)
Frame = -3
Query: 2095 RNSLIRRKQVDSV--HRKAHHQLARELTVPHLVAIGVGSTIGAGVYILVGTVAREHSGPA 1922
+ S+ R+K + + L REL L +G+G+ IG G+++L GT A +GP
Sbjct: 2 KGSVFRKKSIQDLIAATSGEKSLKRELGAFDLTLLGIGAIIGTGIFVLTGTGA-VTAGPG 60
Query: 1921 LTISFLIAGIAAALSAFCYAELASRCPSAGSAYHYTYICIGEGVAWLVGWALILEYTIGG 1742
LTISF++A +A +A YAE AS P +GS Y +TY +GE +A+++GW LILEY +
Sbjct: 61 LTISFVVAALACLFAALSYAEFASSVPVSGSVYTFTYATLGELMAFIIGWDLILEYMLAV 120
Query: 1741 SAVARGISPNL-ALLFGGADSLPVFL--ARQYIPALDIMVDPCAAILVFIVTGLLCVGIK 1571
SAV+ G S + L G LPV L A + + + A ++V +T LL +GIK
Sbjct: 121 SAVSVGWSGYFQSFLSGLGIHLPVALTAAPGAVKGTFTLFNLPAFVIVMAITYLLYLGIK 180
Query: 1570 ESTVAQGIATIANV-CAMLFVIVAGTYLGFKTGWSGYQLPTGYFPFGVNGMLAGSATVFF 1394
ES I I + +LF+ VA Y+ W + P G G+ + +A VFF
Sbjct: 181 ESKRVNNIMVILKILVVLLFIAVAAVYVK-PHNWQ------PFMPMGFGGVFSAAALVFF 233
Query: 1393 AYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLVSMVIVGLVPY-HAMDPDTPI 1217
A+IGFD+V+S AEE KNP +DLP GI +L +C LY+ VS ++ G++P+ D P+
Sbjct: 234 AFIGFDAVSSAAEETKNPAKDLPKGIIFSLLVCTILYVTVSAIMTGVIPFAQFAGVDHPV 293
Query: 1216 STAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILMAMARDGLLPPFFSEINKSTQ 1037
S S G W A II +GAV + + ++ + Q R++ AM+RDGL+P S+++ +
Sbjct: 294 SLVLQSAGQNWVAGIIDIGAVLGMTTVMLVMLYGQTRVMFAMSRDGLVPGSLSKVHPKHK 353
Query: 1036 VPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMVAISVLILRYVPPD 878
P + L + + +LA +V++GTL AF +++++V++LR PD
Sbjct: 354 TPYVATWFFGTMSALLGSLVPLDELAKLVNIGTLSAFVLISVAVIVLRKKQPD 406
>sp|P30825|CTR1_HUMAN High affinity cationic amino acid transporter 1 OS=Homo
sapiens GN=SLC7A1 PE=1 SV=1
Length = 629
Score = 182 bits (461), Expect = 1e-044
Identities = 93/238 (39%), Positives = 146/238 (61%), Gaps = 3/238 (1%)
Frame = -3
Query: 1450 GYFPFGVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLVS 1271
G+ PFG +G+L+G+AT F+A++GFD +A+T EEVKNPQ+ +P+GI A+L IC Y VS
Sbjct: 246 GFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVS 305
Query: 1270 MVIVGLVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILMAM 1091
+ ++PY +D ++P+ AF G + A Y + VG++ AL ++L+GS+ P PR++ AM
Sbjct: 306 AALTLMMPYFCLDNNSPLPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAM 365
Query: 1090 ARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMVAI 911
A DGLL F + +N T+ P+ + +AF D+ L ++S+GTL+A+++VA
Sbjct: 366 AEDGLLFKFLANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAA 425
Query: 910 SVLILRYVP--PDEVPLPASLQDSIDSVSLRHGSNSQDIS-GDDPKGSVGSSKDISKP 746
VL+LRY P P+ V AS D +D +++ D G P+ + S K I P
Sbjct: 426 CVLVLRYQPEQPNLVYQMASTSDELDPADQNELASTNDSQLGFLPEAEMFSLKTILSP 483
Score = 155 bits (390), Expect = 2e-036
Identities = 89/207 (42%), Positives = 122/207 (58%), Gaps = 4/207 (1%)
Frame = -3
Query: 2086 LIRRKQVDSVHRKAHHQLARELTVPHLVAIGVGSTIGAGVYILVGTVAREHSGPALTISF 1907
++RRK VD + +L+R L LVA+GVGST+GAGVY+L G VARE++GPA+ ISF
Sbjct: 13 MLRRKVVDCSREET--RLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPAIVISF 70
Query: 1906 LIAGIAAALSAFCYAELASRCPSAGSAYHYTYICIGEGVAWLVGWALILEYTIGGSAVAR 1727
LIA +A+ L+ CY E +R P GSAY Y+Y+ +GE A++ GW LIL Y IG S+VAR
Sbjct: 71 LIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVAR 130
Query: 1726 GISPNLALLFGG--ADSLPVFLARQYIPALDIMVDPCAAILVFIVTGLLCVGIKESTVAQ 1553
S L G + + L D A I++ I+TGLL +G+KES +
Sbjct: 131 AWSATFDELIGRPIGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVN 190
Query: 1552 GIATIANVCAMLFVIVAGTYLGFKTGW 1472
I T NV + F++V+G G W
Sbjct: 191 KIFTCINVLVLGFIMVSGFVKGSVKNW 217
Score = 62 bits (148), Expect = 2e-008
Identities = 25/51 (49%), Positives = 35/51 (68%)
Frame = -1
Query: 453 FICPFVPLLPIICILINVYLLINLGGDTWARVTVWLIIGVLVYVFYGRTHS 301
F PF+P+LPI+ I +NVYL++ L TW R VW++IG ++Y YG HS
Sbjct: 558 FKVPFLPVLPILSIFVNVYLMMQLDQGTWVRFAVWMLIGFIIYFGYGLWHS 608
>sp|Q09143|CTR1_MOUSE High affinity cationic amino acid transporter 1 OS=Mus
musculus GN=Slc7a1 PE=2 SV=1
Length = 622
Score = 179 bits (454), Expect = 6e-044
Identities = 94/238 (39%), Positives = 145/238 (60%), Gaps = 3/238 (1%)
Frame = -3
Query: 1450 GYFPFGVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLVS 1271
G+ PFG +G+L+G+AT F+A++GFD +A+T EEVKNPQ+ +P+GI A+L IC Y VS
Sbjct: 239 GFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVS 298
Query: 1270 MVIVGLVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILMAM 1091
+ ++PY +D D+P+ AF G + A Y + +G++ AL ++L+GS+ P PR++ AM
Sbjct: 299 AALTLMMPYFCLDIDSPLPGAFKHQGWEEAKYAVAIGSLCALSTSLLGSMFPMPRVIYAM 358
Query: 1090 ARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMVAI 911
A DGLL F ++IN T+ PV + +AF ++ L ++S+GTL+A+++VA
Sbjct: 359 AEDGLLFKFLAKINNRTKTPVIATVTSGAIAAVMAFLFELKDLVDLMSIGTLLAYSLVAA 418
Query: 910 SVLILRYVP--PDEVPLPASLQDSIDSVSLRH-GSNSQDISGDDPKGSVGSSKDISKP 746
VL+LRY P P+ V A + +D V S S+ +G P S K I P
Sbjct: 419 CVLVLRYQPEQPNLVYQMARTTEELDRVDQNELVSASESQTGFLPVAEKFSLKSILSP 476
Score = 159 bits (401), Expect = 9e-038
Identities = 100/245 (40%), Positives = 134/245 (54%), Gaps = 7/245 (2%)
Frame = -3
Query: 2086 LIRRKQVDSVHRKAHHQLARELTVPHLVAIGVGSTIGAGVYILVGTVAREHSGPALTISF 1907
++RRK VD ++ +L+R L LVA+GVGST+GAGVY+L G VARE++GPA+ ISF
Sbjct: 13 MLRRKVVDCSREES--RLSRCLNTYDLVALGVGSTLGAGVYVLAGAVARENAGPAIVISF 70
Query: 1906 LIAGIAAALSAFCYAELASRCPSAGSAYHYTYICIGEGVAWLVGWALILEYTIGGSAVAR 1727
LIA +A+ L+ CY E +R P GSAY Y+Y+ +GE A++ GW LIL Y IG S+VAR
Sbjct: 71 LIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVAR 130
Query: 1726 GISPNLALLFGG--ADSLPVFLARQYIPALDIMVDPCAAILVFIVTGLLCVGIKESTVAQ 1553
S L G + +A L D A I++ I+TGLL +G+KES +
Sbjct: 131 AWSATFDELIGKPIGEFSRQHMALNAPGVLAQTPDIFAVIIIIILTGLLTLGVKESAMVN 190
Query: 1552 GIATIANVCAMLFVIVAGTYLGFKTGWSGYQLPTGYFPFGVNGMLAGSATVFFAYIGFDS 1373
I T NV + F++V+G G W QL F N F GF
Sbjct: 191 KIFTCINVLVLCFIVVSGFVKGSIKNW---QLTEKNFSCNNNDTNVKYGEGGFMPFGFSG 247
Query: 1372 VASTA 1358
V S A
Sbjct: 248 VLSGA 252
Score = 60 bits (145), Expect = 4e-008
Identities = 24/51 (47%), Positives = 34/51 (66%)
Frame = -1
Query: 453 FICPFVPLLPIICILINVYLLINLGGDTWARVTVWLIIGVLVYVFYGRTHS 301
F PFVP+LP++ I +N+YL++ L TW R VW++IG +Y YG HS
Sbjct: 551 FKVPFVPVLPVLSIFVNIYLMMQLDQGTWVRFAVWMLIGFTIYFGYGIWHS 601
>sp|P30823|CTR1_RAT High affinity cationic amino acid transporter 1 OS=Rattus
norvegicus GN=Slc7a1 PE=2 SV=1
Length = 624
Score = 179 bits (452), Expect = 1e-043
Identities = 94/238 (39%), Positives = 144/238 (60%), Gaps = 3/238 (1%)
Frame = -3
Query: 1450 GYFPFGVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLVS 1271
G+ PFG +G+L+G+AT F+A++GFD +A+T EEVKNPQ+ +P+GI A+L IC Y VS
Sbjct: 241 GFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVS 300
Query: 1270 MVIVGLVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILMAM 1091
+ ++PY +D D+P+ AF G + A Y + VG++ AL ++ +GS+ P PR++ AM
Sbjct: 301 AALTLMMPYFCLDTDSPLPGAFKYRGWEEAKYAVAVGSLCALSTSPLGSMFPMPRVIYAM 360
Query: 1090 ARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMVAI 911
A DGLL F ++IN T+ P+ + +AF ++ L ++S+GTL+A+++VA
Sbjct: 361 AEDGLLFKFLAKINDRTKTPIIATVTSGAIAAVMAFLFELKDLVDLMSIGTLLAYSLVAA 420
Query: 910 SVLILRYVP--PDEVPLPASLQDSIDSVSLRH-GSNSQDISGDDPKGSVGSSKDISKP 746
VL+LRY P P+ V A D +D V S S+ +G P S K I P
Sbjct: 421 CVLVLRYQPEQPNLVYQMARTTDELDQVDQNEMVSASESQTGFLPAAEKFSLKTILSP 478
Score = 158 bits (397), Expect = 3e-037
Identities = 90/207 (43%), Positives = 124/207 (59%), Gaps = 4/207 (1%)
Frame = -3
Query: 2086 LIRRKQVDSVHRKAHHQLARELTVPHLVAIGVGSTIGAGVYILVGTVAREHSGPALTISF 1907
++RRK VD ++ +L+R L LVA+GVGST+GAGVY+L G VARE++GPA+ ISF
Sbjct: 13 MLRRKVVDCSREES--RLSRCLNTYDLVALGVGSTLGAGVYVLAGAVARENAGPAIVISF 70
Query: 1906 LIAGIAAALSAFCYAELASRCPSAGSAYHYTYICIGEGVAWLVGWALILEYTIGGSAVAR 1727
LIA +A+ L+ CY E +R P GSAY Y+Y+ +GE A++ GW LIL Y IG S+VAR
Sbjct: 71 LIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVAR 130
Query: 1726 GISPNLALLFGG--ADSLPVFLARQYIPALDIMVDPCAAILVFIVTGLLCVGIKESTVAQ 1553
S L G + +A L D A I++ I+TGLL +G+KES +
Sbjct: 131 AWSATFDELIGKPIGEFSRQHMALNAPGVLAQTPDIFAVIIIIILTGLLTLGVKESAMVN 190
Query: 1552 GIATIANVCAMLFVIVAGTYLGFKTGW 1472
I T NV + F++V+G G W
Sbjct: 191 KIFTCINVLVLCFIMVSGFVKGSIENW 217
Score = 58 bits (139), Expect = 2e-007
Identities = 23/51 (45%), Positives = 33/51 (64%)
Frame = -1
Query: 453 FICPFVPLLPIICILINVYLLINLGGDTWARVTVWLIIGVLVYVFYGRTHS 301
F PFVP+LP++ I +N+YL++ L TW R VW++I +Y YG HS
Sbjct: 553 FKVPFVPVLPVLSIFVNIYLMMQLDQGTWVRFAVWMLIAFAIYFGYGVWHS 603
>sp|O08812|CTR3_RAT Cationic amino acid transporter 3 OS=Rattus norvegicus
GN=Slc7a3 PE=2 SV=1
Length = 619
Score = 174 bits (439), Expect = 3e-042
Identities = 77/193 (39%), Positives = 128/193 (66%)
Frame = -3
Query: 1450 GYFPFGVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLVS 1271
G+ PFG+ G+L G+AT F+A++GFD +A+T EE +NPQR +P+GI +LSIC Y VS
Sbjct: 244 GFMPFGLEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSICFLAYFGVS 303
Query: 1270 MVIVGLVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILMAM 1091
+ ++PY+ + P++P+ AF G + A Y++ +G++ AL ++L+GS+ P PR++ AM
Sbjct: 304 SALTLMMPYYKLQPESPLPEAFTYVGWEPARYLVAIGSLCALSTSLLGSMFPMPRVIYAM 363
Query: 1090 ARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMVAI 911
A DGLL + ++ T P+ + +AF +++ L ++S+GTL+A+++V+I
Sbjct: 364 AEDGLLFRVLARVHNGTHTPIVATVVSGVIAAFMAFLFELTDLVDLMSIGTLLAYSLVSI 423
Query: 910 SVLILRYVPPDEV 872
VLILRY P E+
Sbjct: 424 CVLILRYQPDQEM 436
Score = 139 bits (348), Expect = 1e-031
Identities = 79/191 (41%), Positives = 113/191 (59%), Gaps = 2/191 (1%)
Frame = -3
Query: 2038 QLARELTVPHLVAIGVGSTIGAGVYILVGTVAREHSGPALTISFLIAGIAAALSAFCYAE 1859
+LAR L+ LVA+GVGST+GAGVY+L G VA+E +GP++ I FL+A +++ L+ CYAE
Sbjct: 27 RLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKEKAGPSIVICFLVAALSSVLAGLCYAE 86
Query: 1858 LASRCPSAGSAYHYTYICIGEGVAWLVGWALILEYTIGGSAVARGISPNLALLFGG--AD 1685
+R P +GSAY Y+Y+ +GE A+ GW LIL Y IG ++VAR S L G +
Sbjct: 87 FGARVPGSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISQ 146
Query: 1684 SLPVFLARQYIPALDIMVDPCAAILVFIVTGLLCVGIKESTVAQGIATIANVCAMLFVIV 1505
+L + L D A LV ++TGLL +G ES + + T N+ + FVI+
Sbjct: 147 TLKGTILLNMPHVLAEYPDFFALALVLLLTGLLVLGANESGLVTKVFTGMNLLVLGFVII 206
Query: 1504 AGTYLGFKTGW 1472
+G G W
Sbjct: 207 SGFIKGELRNW 217
Score = 63 bits (151), Expect = 9e-009
Identities = 26/51 (50%), Positives = 35/51 (68%)
Frame = -1
Query: 453 FICPFVPLLPIICILINVYLLINLGGDTWARVTVWLIIGVLVYVFYGRTHS 301
F P VPLLP++ I +NVYL++ + DTWAR VW++IG +Y YG HS
Sbjct: 539 FKVPVVPLLPLVSIFVNVYLMMQMTADTWARFGVWMLIGFAIYFGYGIQHS 589
>sp|Q8WY07|CTR3_HUMAN Cationic amino acid transporter 3 OS=Homo sapiens
GN=SLC7A3 PE=1 SV=1
Length = 619
Score = 171 bits (432), Expect = 2e-041
Identities = 78/192 (40%), Positives = 125/192 (65%)
Frame = -3
Query: 1450 GYFPFGVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLVS 1271
G+ PFG G+L G+AT F+A++GFD +A+T EE +NPQR +P+GI +LS+C Y VS
Sbjct: 244 GFVPFGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVS 303
Query: 1270 MVIVGLVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILMAM 1091
+ ++PY+ + P++P+ AF G A Y++ VG++ AL ++L+GS+ P PR++ AM
Sbjct: 304 SALTLMMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAM 363
Query: 1090 ARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMVAI 911
A DGLL + I+ T+ P+ + +AF ++ L ++S+GTL+A+++V+I
Sbjct: 364 AEDGLLFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSI 423
Query: 910 SVLILRYVPPDE 875
VLILRY P E
Sbjct: 424 CVLILRYQPDQE 435
Score = 142 bits (356), Expect = 1e-032
Identities = 83/207 (40%), Positives = 123/207 (59%), Gaps = 4/207 (1%)
Frame = -3
Query: 2086 LIRRKQVDSVHRKAHHQLARELTVPHLVAIGVGSTIGAGVYILVGTVAREHSGPALTISF 1907
L+RR+ ++S A +LAR L+ LVA+GVGST+GAGVY+L G VA++ +GP++ I F
Sbjct: 13 LVRRRTLES--GMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICF 70
Query: 1906 LIAGIAAALSAFCYAELASRCPSAGSAYHYTYICIGEGVAWLVGWALILEYTIGGSAVAR 1727
L+A +++ L+ CYAE +R P +GSAY Y+Y+ +GE A+ GW LIL Y IG ++VAR
Sbjct: 71 LVAALSSVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVAR 130
Query: 1726 GISPNLALLFGG--ADSLPVFLARQYIPALDIMVDPCAAILVFIVTGLLCVGIKESTVAQ 1553
S L G + +L +A L D A LV ++TGLL +G ES +
Sbjct: 131 AWSSAFDNLIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVT 190
Query: 1552 GIATIANVCAMLFVIVAGTYLGFKTGW 1472
+ T N+ + FV+++G G W
Sbjct: 191 KVFTGVNLLVLGFVMISGFVKGDVHNW 217
>sp|P52569|CTR2_HUMAN Low affinity cationic amino acid transporter 2 OS=Homo
sapiens GN=SLC7A2 PE=1 SV=2
Length = 658
Score = 171 bits (431), Expect = 3e-041
Identities = 79/189 (41%), Positives = 122/189 (64%)
Frame = -3
Query: 1450 GYFPFGVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLVS 1271
G+ P+G G LAG+AT F+A++GFD +A+T EEV+NPQ+ +P+GI +L +C Y VS
Sbjct: 248 GFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVS 307
Query: 1270 MVIVGLVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILMAM 1091
+ ++PY+ +D +P+ AF G A Y++ G++ AL ++L+GSI P PR++ AM
Sbjct: 308 AALTLMMPYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAM 367
Query: 1090 ARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMVAI 911
A DGLL ++IN T+ P+ + +AF D+ L M+S+GTL+A+++VA
Sbjct: 368 AEDGLLFKCLAQINSKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAA 427
Query: 910 SVLILRYVP 884
VLILRY P
Sbjct: 428 CVLILRYQP 436
Score = 149 bits (375), Expect = 9e-035
Identities = 88/208 (42%), Positives = 120/208 (57%), Gaps = 6/208 (2%)
Frame = -3
Query: 2086 LIRRKQVDSVHRKAHHQLARELTVPHLVAIGVGSTIGAGVYILVGTVAREHSGPALTISF 1907
LIRRK V ++ +L R L+ L+A+GVGST+GAGVY+L G VA+ SGP++ +SF
Sbjct: 14 LIRRKIV-TLDSLEDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSF 72
Query: 1906 LIAGIAAALSAFCYAELASRCPSAGSAYHYTYICIGEGVAWLVGWALILEYTIGGSAVAR 1727
LIA +A+ ++ CYAE +R P GSAY YTY+ +GE A++ GW LIL Y IG S+VAR
Sbjct: 73 LIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVAR 132
Query: 1726 GISPNLALLFGGADSLPVFLA---RQYIPALDIMVDPCAAILVFIVTGLLCVGIKESTVA 1556
S L + + FL R L D A L+ ++ GLL G+KES
Sbjct: 133 AWSGTFDELL--SKQIGQFLRTYFRMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESAWV 190
Query: 1555 QGIATIANVCAMLFVIVAGTYLGFKTGW 1472
+ T N+ +LFV+VAG G W
Sbjct: 191 NKVFTAVNILVLLFVMVAGFVKGNVANW 218
>sp|P70423|CTR3_MOUSE Cationic amino acid transporter 3 OS=Mus musculus
GN=Slc7a3 PE=2 SV=1
Length = 618
Score = 169 bits (426), Expect = 1e-040
Identities = 74/193 (38%), Positives = 129/193 (66%)
Frame = -3
Query: 1450 GYFPFGVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLVS 1271
G+ PFG+ G+L G+AT F+A++GFD +A+T EE +NPQR +P+GI ++ IC Y VS
Sbjct: 244 GFMPFGLEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISMFICFLAYFGVS 303
Query: 1270 MVIVGLVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILMAM 1091
+ ++PY+ + P++P+ AF+ G + A Y++ +G++ AL ++L+GS+ P PR++ +M
Sbjct: 304 SALTLMMPYYKLHPESPLPEAFSYVGWEPARYLVAIGSLCALSTSLLGSMFPMPRVMYSM 363
Query: 1090 ARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMVAI 911
A DGLL ++++ T +P+ + +AF +++ L ++S+GTL+A ++V+I
Sbjct: 364 AEDGLLFRVLAKVHSVTHIPIVATLVSGVIAAFMAFLFELTDLVDLMSIGTLLAHSLVSI 423
Query: 910 SVLILRYVPPDEV 872
VLILRY P E+
Sbjct: 424 CVLILRYQPDQEM 436
Score = 137 bits (344), Expect = 4e-031
Identities = 77/191 (40%), Positives = 114/191 (59%), Gaps = 2/191 (1%)
Frame = -3
Query: 2038 QLARELTVPHLVAIGVGSTIGAGVYILVGTVAREHSGPALTISFLIAGIAAALSAFCYAE 1859
+LAR L+ LVA+GVGST+GAGVY+L G VA++ +GP++ I FL+A +++ L+ CYAE
Sbjct: 27 RLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAE 86
Query: 1858 LASRCPSAGSAYHYTYICIGEGVAWLVGWALILEYTIGGSAVARGISPNLALLFGG--AD 1685
+R P +GSAY Y+Y+ +GE A+ GW LIL Y IG ++VAR S L G +
Sbjct: 87 FGARVPGSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISR 146
Query: 1684 SLPVFLARQYIPALDIMVDPCAAILVFIVTGLLCVGIKESTVAQGIATIANVCAMLFVIV 1505
+L + + L D A LV ++TGLL +G +S + + T N+ + FVI+
Sbjct: 147 TLKGTILLKMPHVLAEYPDFFALALVLLLTGLLVLGASKSALVTKVFTGMNLLVLSFVII 206
Query: 1504 AGTYLGFKTGW 1472
+G G W
Sbjct: 207 SGFIKGELRNW 217
Score = 59 bits (142), Expect = 1e-007
Identities = 24/51 (47%), Positives = 34/51 (66%)
Frame = -1
Query: 453 FICPFVPLLPIICILINVYLLINLGGDTWARVTVWLIIGVLVYVFYGRTHS 301
F P VPLLP++ I +NVYL++ + TWAR +W++IG +Y YG HS
Sbjct: 538 FKVPAVPLLPLVSIFVNVYLMMQMTAGTWARFGIWMLIGFAIYFGYGIQHS 588
>sp|P18581|CTR2_MOUSE Low affinity cationic amino acid transporter 2 OS=Mus
musculus GN=Slc7a2 PE=2 SV=2
Length = 657
Score = 165 bits (417), Expect = 1e-039
Identities = 81/189 (42%), Positives = 122/189 (64%), Gaps = 1/189 (0%)
Frame = -3
Query: 1450 GYFPFGVNGMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLVS 1271
G+ P+G G LAG+AT F+A++GFD +A+T EEV+NPQ+ +P+GI +L +C Y VS
Sbjct: 248 GFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVS 307
Query: 1270 MVIVGLVPYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILMAM 1091
+ ++PY+ +D +P+ AF A Y++ G++ AL ++L+GS+ P PRIL AM
Sbjct: 308 AALTLMMPYYLLDEKSPLPVAFEYVRWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAM 367
Query: 1090 ARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMVAI 911
ARDGLL F + ++K Q PV + +AF D+ L M+S+GTL+A+++VA
Sbjct: 368 ARDGLLFRFLARVSK-RQSPVAATMTAGVISAVMAFLFDLKALVDMMSIGTLMAYSLVAA 426
Query: 910 SVLILRYVP 884
VLILRY P
Sbjct: 427 CVLILRYQP 435
Score = 148 bits (373), Expect = 2e-034
Identities = 88/207 (42%), Positives = 116/207 (56%), Gaps = 4/207 (1%)
Frame = -3
Query: 2086 LIRRKQVDSVHRKAHHQLARELTVPHLVAIGVGSTIGAGVYILVGTVAREHSGPALTISF 1907
LIRRK V ++ +L R LT L+A+GVGST+GAGVY+L G VA+ SGP++ +SF
Sbjct: 14 LIRRKIV-TLDSLEDSKLCRCLTTVDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSF 72
Query: 1906 LIAGIAAALSAFCYAELASRCPSAGSAYHYTYICIGEGVAWLVGWALILEYTIGGSAVAR 1727
LIA +A+ ++ CYAE +R P GSAY YTY+ +GE A++ GW LIL Y IG S+VAR
Sbjct: 73 LIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVAR 132
Query: 1726 GISPNLALLFGG--ADSLPVFLARQYIPALDIMVDPCAAILVFIVTGLLCVGIKESTVAQ 1553
S L + Y L D A LV ++ GLL G+KES
Sbjct: 133 AWSGTFDELLNKQIGQFFKTYFKMNY-TGLAEYPDFFAVCLVLLLAGLLSFGVKESAWVN 191
Query: 1552 GIATIANVCAMLFVIVAGTYLGFKTGW 1472
T N+ +LFV+VAG G W
Sbjct: 192 KFFTAINILVLLFVMVAGFVKGNVANW 218
>sp|P63349|Y1999_MYCTU Uncharacterized transporter Rv1999c/MT2055
OS=Mycobacterium tuberculosis GN=Rv1999c PE=3 SV=1
Length = 440
Score = 97 bits (239), Expect = 5e-019
Identities = 71/247 (28%), Positives = 115/247 (46%), Gaps = 13/247 (5%)
Frame = -3
Query: 1621 AAILVFIVTGLLCVGIKESTVAQGIATIANVCAMLFVIVAGTYLGFKTGWSGYQLPTGYF 1442
A +V +T + GI++S + +A V +L +V Y SG P
Sbjct: 130 AVAVVVALTAVNYAGIQKSAWLTR-SIVAVVLVVLTAVVVAAY------GSGAADP-ARL 181
Query: 1441 PFGVN----GMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLV 1274
GV+ GML + +FFA+ G+ +A+ EEV++P R +P I AL I A+Y LV
Sbjct: 182 DIGVDAHVWGMLQAAGLLFFAFAGYARIATLGEEVRDPARTIPRAIPLALGITLAVYALV 241
Query: 1273 SMVIVGLV-PYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILM 1097
++ ++ ++ P P+S A G+ W ++ +GA A +L+ IL R +
Sbjct: 242 AVAVIAVLGPQRLARAAAPLSEAMRVAGVNWLIPVVQIGAAVAALGSLLALILGVSRTTL 301
Query: 1096 AMARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMV 917
AMARD LP + + ++ +VP ++ LA D+ G S G LV + +
Sbjct: 302 AMARDRHLPRWLAAVHPRFKVPFRAELVVGAVVAALAATADIRGAIGFSSFGVLVYYAIA 361
Query: 916 AISVLIL 896
S L L
Sbjct: 362 NASALTL 368
>sp|P63350|Y2022_MYCBO Uncharacterized transporter Mb2022c OS=Mycobacterium
bovis GN=Mb2022c PE=3 SV=1
Length = 440
Score = 97 bits (239), Expect = 5e-019
Identities = 71/247 (28%), Positives = 115/247 (46%), Gaps = 13/247 (5%)
Frame = -3
Query: 1621 AAILVFIVTGLLCVGIKESTVAQGIATIANVCAMLFVIVAGTYLGFKTGWSGYQLPTGYF 1442
A +V +T + GI++S + +A V +L +V Y SG P
Sbjct: 130 AVAVVVALTAVNYAGIQKSAWLTR-SIVAVVLVVLTAVVVAAY------GSGAADP-ARL 181
Query: 1441 PFGVN----GMLAGSATVFFAYIGFDSVASTAEEVKNPQRDLPLGIGAALSICCALYMLV 1274
GV+ GML + +FFA+ G+ +A+ EEV++P R +P I AL I A+Y LV
Sbjct: 182 DIGVDAHVWGMLQAAGLLFFAFAGYARIATLGEEVRDPARTIPRAIPLALGITLAVYALV 241
Query: 1273 SMVIVGLV-PYHAMDPDTPISTAFASHGMQWAAYIITVGAVTALCSTLMGSILPQPRILM 1097
++ ++ ++ P P+S A G+ W ++ +GA A +L+ IL R +
Sbjct: 242 AVAVIAVLGPQRLARAAAPLSEAMRVAGVNWLIPVVQIGAAVAALGSLLALILGVSRTTL 301
Query: 1096 AMARDGLLPPFFSEINKSTQVPVKSXXXXXXXXXXLAFFMDVSQLAGMVSVGTLVAFTMV 917
AMARD LP + + ++ +VP ++ LA D+ G S G LV + +
Sbjct: 302 AMARDRHLPRWLAAVHPRFKVPFRAELVVGAVVAALAATADIRGAIGFSSFGVLVYYAIA 361
Query: 916 AISVLIL 896
S L L
Sbjct: 362 NASALTL 368
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,407,642,047
Number of Sequences: 462764
Number of Extensions: 3407642047
Number of Successful Extensions: 34563130
Number of sequences better than 0.0: 0
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