BLASTX 7.6.2
Query= RU04042 /QuerySize=653
(652 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7T339|CHMP5_DANRE Charged multivesicular body protein 5 OS=D... 173 1e-042
sp|Q9D7S9|CHMP5_MOUSE Charged multivesicular body protein 5 OS=M... 172 2e-042
sp|Q4QQV8|CHMP5_RAT Charged multivesicular body protein 5 OS=Rat... 172 2e-042
sp|Q9NZZ3|CHMP5_HUMAN Charged multivesicular body protein 5 OS=H... 170 7e-042
sp|Q5RBR3|CHMP5_PONAB Charged multivesicular body protein 5 OS=P... 170 7e-042
sp|Q54JK4|CHMP5_DICDI Charged multivesicular body protein 5 OS=D... 169 2e-041
sp|Q5FW29|CHMP5_XENTR Charged multivesicular body protein 5 OS=X... 166 2e-040
sp|Q6DD52|CHMP5_XENLA Charged multivesicular body protein 5 OS=X... 164 4e-040
sp|O74422|YQ56_SCHPO Uncharacterized protein C162.06c OS=Schizos... 146 2e-034
sp|Q03390|VPS60_YEAST Vacuolar protein-sorting-associated protei... 82 2e-015
sp|Q9SZE4|VP322_ARATH Vacuolar protein sorting-associated protei... 81 5e-015
sp|Q6FW96|SNF7_CANGA Vacuolar-sorting protein SNF7 OS=Candida gl... 60 7e-009
>sp|Q7T339|CHMP5_DANRE Charged multivesicular body protein 5 OS=Danio rerio
GN=chmp5 PE=2 SV=1
Length = 220
Score = 173 bits (437), Expect = 1e-042
Identities = 85/181 (46%), Positives = 127/181 (70%), Gaps = 2/181 (1%)
Frame = -1
Query: 559 MKRVFGAKKDKEPPPSVGDASDRINKRGDTVDEKIKKLDVELNRYKEQIKKTRPGPAQEA 380
M R+FG K K PPP++ D ++ R ++VD+KI +LD EL +YK+Q+KK R GP++
Sbjct: 1 MNRIFGRGKPKGPPPNLTDCISGVDSRAESVDKKIARLDAELMKYKDQMKKMRDGPSKNM 60
Query: 379 VKSRAMRVLKQKRMYEGQRDMLYNQTFNLDQVAFASEGIKDAQQTMTALKSANKELKGMM 200
VK +AMRVLKQKRMYEGQRD L Q+FN++Q + + +KD + T+ A+K KE+K
Sbjct: 61 VKQKAMRVLKQKRMYEGQRDQLMQQSFNMEQANYTIQTLKDTKTTVEAMKIGAKEMKKAY 120
Query: 199 KTVKIQDIDNLQDEMMDLM-DVSKIQETLGRSYSVPDDIDEEELMGELDALEADMGMETE 23
K VKI I++LQD++ D+M D +++QE L RSY P +IDE++L ELDAL ++ ++ +
Sbjct: 121 KNVKIDQIEDLQDQLEDMMEDANEVQEALSRSYGTP-EIDEDDLEAELDALGDELLLDDD 179
Query: 22 S 20
+
Sbjct: 180 N 180
>sp|Q9D7S9|CHMP5_MOUSE Charged multivesicular body protein 5 OS=Mus musculus
GN=Chmp5 PE=2 SV=1
Length = 219
Score = 172 bits (434), Expect = 2e-042
Identities = 87/181 (48%), Positives = 125/181 (69%), Gaps = 2/181 (1%)
Frame = -1
Query: 559 MKRVFGAKKDKEPPPSVGDASDRINKRGDTVDEKIKKLDVELNRYKEQIKKTRPGPAQEA 380
M R FG K K PPPS+ D ++ R +++D+KI +LD EL +YK+QIKK R GPA+
Sbjct: 1 MNRFFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM 60
Query: 379 VKSRAMRVLKQKRMYEGQRDMLYNQTFNLDQVAFASEGIKDAQQTMTALKSANKELKGMM 200
VK +A+RVLKQKRMYE QRD L Q+FN++Q + + +KD + T+ A+K KE+K
Sbjct: 61 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY 120
Query: 199 KTVKIQDIDNLQDEMMDLM-DVSKIQETLGRSYSVPDDIDEEELMGELDALEADMGMETE 23
K VKI I++LQD++ D+M D ++IQE LGRSY P ++DE++L ELDAL ++ + +
Sbjct: 121 KEVKIDQIEDLQDQLEDMMEDANEIQEALGRSYGTP-ELDEDDLEAELDALGDELLADED 179
Query: 22 S 20
S
Sbjct: 180 S 180
>sp|Q4QQV8|CHMP5_RAT Charged multivesicular body protein 5 OS=Rattus norvegicus
GN=Chmp5 PE=2 SV=1
Length = 219
Score = 172 bits (434), Expect = 2e-042
Identities = 87/181 (48%), Positives = 125/181 (69%), Gaps = 2/181 (1%)
Frame = -1
Query: 559 MKRVFGAKKDKEPPPSVGDASDRINKRGDTVDEKIKKLDVELNRYKEQIKKTRPGPAQEA 380
M R FG K K PPPS+ D ++ R +++D+KI +LD EL +YK+QIKK R GPA+
Sbjct: 1 MNRFFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM 60
Query: 379 VKSRAMRVLKQKRMYEGQRDMLYNQTFNLDQVAFASEGIKDAQQTMTALKSANKELKGMM 200
VK +A+RVLKQKRMYE QRD L Q+FN++Q + + +KD + T+ A+K KE+K
Sbjct: 61 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY 120
Query: 199 KTVKIQDIDNLQDEMMDLM-DVSKIQETLGRSYSVPDDIDEEELMGELDALEADMGMETE 23
K VKI I++LQD++ D+M D ++IQE LGRSY P ++DE++L ELDAL ++ + +
Sbjct: 121 KEVKIDQIEDLQDQLEDMMEDANEIQEALGRSYGTP-ELDEDDLEAELDALGDELLADED 179
Query: 22 S 20
S
Sbjct: 180 S 180
>sp|Q9NZZ3|CHMP5_HUMAN Charged multivesicular body protein 5 OS=Homo sapiens
GN=CHMP5 PE=1 SV=1
Length = 219
Score = 170 bits (430), Expect = 7e-042
Identities = 86/181 (47%), Positives = 125/181 (69%), Gaps = 2/181 (1%)
Frame = -1
Query: 559 MKRVFGAKKDKEPPPSVGDASDRINKRGDTVDEKIKKLDVELNRYKEQIKKTRPGPAQEA 380
M R+FG K K PPPS+ D ++ R +++D+KI +LD EL +YK+QIKK R GPA+
Sbjct: 1 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM 60
Query: 379 VKSRAMRVLKQKRMYEGQRDMLYNQTFNLDQVAFASEGIKDAQQTMTALKSANKELKGMM 200
VK +A+RVLKQKRMYE QRD L Q+FN++Q + + +KD + T+ A+K KE+K
Sbjct: 61 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY 120
Query: 199 KTVKIQDIDNLQDEMMDLM-DVSKIQETLGRSYSVPDDIDEEELMGELDALEADMGMETE 23
K VKI I++LQD++ D+M D ++IQE L RSY P ++DE++L ELDAL ++ + +
Sbjct: 121 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTP-ELDEDDLEAELDALGDELLADED 179
Query: 22 S 20
S
Sbjct: 180 S 180
>sp|Q5RBR3|CHMP5_PONAB Charged multivesicular body protein 5 OS=Pongo abelii
GN=CHMP5 PE=2 SV=1
Length = 219
Score = 170 bits (430), Expect = 7e-042
Identities = 86/181 (47%), Positives = 125/181 (69%), Gaps = 2/181 (1%)
Frame = -1
Query: 559 MKRVFGAKKDKEPPPSVGDASDRINKRGDTVDEKIKKLDVELNRYKEQIKKTRPGPAQEA 380
M R+FG K K PPPS+ D ++ R +++D+KI +LD EL +YK+QIKK R GPA+
Sbjct: 1 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM 60
Query: 379 VKSRAMRVLKQKRMYEGQRDMLYNQTFNLDQVAFASEGIKDAQQTMTALKSANKELKGMM 200
VK +A+RVLKQKRMYE QRD L Q+FN++Q + + +KD + T+ A+K KE+K
Sbjct: 61 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY 120
Query: 199 KTVKIQDIDNLQDEMMDLM-DVSKIQETLGRSYSVPDDIDEEELMGELDALEADMGMETE 23
K VKI I++LQD++ D+M D ++IQE L RSY P ++DE++L ELDAL ++ + +
Sbjct: 121 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTP-ELDEDDLEAELDALGDELLADED 179
Query: 22 S 20
S
Sbjct: 180 S 180
>sp|Q54JK4|CHMP5_DICDI Charged multivesicular body protein 5 OS=Dictyostelium
discoideum GN=chmp5 PE=3 SV=1
Length = 215
Score = 169 bits (426), Expect = 2e-041
Identities = 85/186 (45%), Positives = 130/186 (69%), Gaps = 5/186 (2%)
Frame = -1
Query: 556 KRVFGAKKDKEPPPSVGDASDRINKRGDTVDEKIKKLDVELNRYKEQIKKTRPGPAQEAV 377
KR FG + +P P++ +A+ RI R +DEKI L+ EL Y +QIK TRPGPAQ A+
Sbjct: 2 KRFFGV-SNNQPAPTLDEATKRIGGRMGQMDEKINGLNQELLAYDKQIKATRPGPAQNAI 60
Query: 376 KSRAMRVLKQKRMYEGQRDMLYNQTFNLDQVAFASEGIKDAQQTMTALKSANKELKGMMK 197
K +A+RVL+QK+MYE QRD + + +FN++Q FA+E ++D T++A+K K++K +K
Sbjct: 61 KQKAIRVLQQKKMYERQRDQMASTSFNMEQTKFATESMRDTITTVSAMKQGAKDMKTQLK 120
Query: 196 TVKIQDIDNLQDEMMDLMDV-SKIQETLGRSYSVPDDIDEEELMGELDALEADMGMETES 20
+KI+D+D++QDEM DL+D ++IQE+LGR+Y PD +DE EL EL ++ ++ +E
Sbjct: 121 HIKIEDVDDMQDEMQDLLDYNNEIQESLGRAYQTPDTLDESELEAELMSMGEELELEA-- 178
Query: 19 DGVPSY 2
+PSY
Sbjct: 179 -SMPSY 183
>sp|Q5FW29|CHMP5_XENTR Charged multivesicular body protein 5 OS=Xenopus
tropicalis GN=chmp5 PE=2 SV=1
Length = 219
Score = 166 bits (418), Expect = 2e-040
Identities = 82/181 (45%), Positives = 126/181 (69%), Gaps = 2/181 (1%)
Frame = -1
Query: 559 MKRVFGAKKDKEPPPSVGDASDRINKRGDTVDEKIKKLDVELNRYKEQIKKTRPGPAQEA 380
M R+FG K K PP ++ D ++ R +++D+KI +LD EL +YK+Q+KK R GP++
Sbjct: 1 MNRLFGKSKPKVPPSTLTDCISNVDSRSESIDKKISRLDAELVKYKDQMKKMREGPSKNM 60
Query: 379 VKSRAMRVLKQKRMYEGQRDMLYNQTFNLDQVAFASEGIKDAQQTMTALKSANKELKGMM 200
VK +A+RVLKQKRMYE QRD L Q+FN++Q +A + +KD + T+ A+K KE+K
Sbjct: 61 VKQKALRVLKQKRMYEQQRDNLNQQSFNMEQTNYAIQSLKDTKTTVDAMKVGAKEMKKAY 120
Query: 199 KTVKIQDIDNLQDEMMDLMD-VSKIQETLGRSYSVPDDIDEEELMGELDALEADMGMETE 23
K VKI I++LQD++ D+M+ ++IQE L RSY P +IDE++L ELDAL ++ ++ +
Sbjct: 121 KQVKIDQIEDLQDQLEDMMENANEIQEALSRSYGTP-EIDEDDLEAELDALGDELLLDDD 179
Query: 22 S 20
+
Sbjct: 180 T 180
>sp|Q6DD52|CHMP5_XENLA Charged multivesicular body protein 5 OS=Xenopus laevis
GN=chmp5 PE=2 SV=1
Length = 219
Score = 164 bits (415), Expect = 4e-040
Identities = 81/181 (44%), Positives = 126/181 (69%), Gaps = 2/181 (1%)
Frame = -1
Query: 559 MKRVFGAKKDKEPPPSVGDASDRINKRGDTVDEKIKKLDVELNRYKEQIKKTRPGPAQEA 380
M R+FG K K PPP++ D ++ R +++++KI +LD EL +YK+Q+KK R GP++
Sbjct: 1 MNRIFGKSKPKVPPPTLTDCITNVDGRAESIEKKISRLDAELIKYKDQMKKMREGPSKNM 60
Query: 379 VKSRAMRVLKQKRMYEGQRDMLYNQTFNLDQVAFASEGIKDAQQTMTALKSANKELKGMM 200
VK +A+RVLKQKRMYE QRD L Q+FN++Q + + +KD + T+ A+K KE+K
Sbjct: 61 VKQKALRVLKQKRMYEQQRDNLNQQSFNMEQANYTIQTLKDTKTTVDAMKVGAKEMKKAY 120
Query: 199 KTVKIQDIDNLQDEMMDLMD-VSKIQETLGRSYSVPDDIDEEELMGELDALEADMGMETE 23
K VKI I++LQD++ D+M+ ++IQE L RSY P +IDE++L ELDAL ++ ++ +
Sbjct: 121 KQVKIDQIEDLQDQLEDMMENANEIQEALSRSYGTP-EIDEDDLEAELDALGDELLLDDD 179
Query: 22 S 20
+
Sbjct: 180 T 180
>sp|O74422|YQ56_SCHPO Uncharacterized protein C162.06c OS=Schizosaccharomyces
pombe GN=SPCC162.06c PE=2 SV=1
Length = 210
Score = 146 bits (366), Expect = 2e-034
Identities = 73/174 (41%), Positives = 115/174 (66%), Gaps = 2/174 (1%)
Frame = -1
Query: 559 MKRVFGAKKDKEPPPSVGDASDRINKRGDTVDEKIKKLDVELNRYKEQIKKTRPGPAQEA 380
M R+FG K +P S+ DA D ++KR D+V+ KI KLD +L+ ++++I TRPGP Q A
Sbjct: 1 MHRLFGRKPPTQPTASLTDAIDSLDKRSDSVEVKIAKLDAQLSVFQQKIANTRPGPGQTA 60
Query: 379 VKSRAMRVLKQKRMYEGQRDMLYNQTFNLDQVAFASEGIKDAQQTMTALKSANKELKGMM 200
+K RAM VL+QK++YE Q L Q+FN++Q A +E +K+ T+ ++ ++LK
Sbjct: 61 LKQRAMNVLRQKKIYESQLQQLQQQSFNMEQAAMTTESLKNTMATVQTMQETARQLKSQS 120
Query: 199 KTVKIQDIDNLQDEMMDLMDVS-KIQETLGRSYSVPDDIDEEELMGELDALEAD 41
K V I+ I+ LQDE+ D MD + ++ E LG++ + ++DEEEL EL+AL+ +
Sbjct: 121 KNVSIEKIEKLQDEIQDYMDAAGELNEVLGQNMT-DINVDEEELDAELEALQQE 173
>sp|Q03390|VPS60_YEAST Vacuolar protein-sorting-associated protein 60
OS=Saccharomyces cerevisiae GN=VPS60 PE=1 SV=2
Length = 229
Score = 82 bits (202), Expect = 2e-015
Identities = 50/192 (26%), Positives = 103/192 (53%), Gaps = 9/192 (4%)
Frame = -1
Query: 559 MKRVFGAKKDKEPPPSVGDASDRINKRGDTVDEKIKKLD---VELNRYKEQIKKT--RPG 395
M R+FG K + +++ +N+ ++ +I +LD +LN + I+K R
Sbjct: 1 MNRIFGYGNKKSHDQLLQESNQSMNQAQQSLSNRISQLDTQIAQLNFQLQNIQKNLQRSN 60
Query: 394 PAQEAVKSRAMRVLKQKRMYEGQRDMLYNQTFNLDQVAFASEGIKDAQQTMTALKSANKE 215
Q +++ +A+++L +++ E +D L +Q++++ Q ++ +++ T+ ALK N
Sbjct: 61 NKQPSLRKQALKILNKRKQLENMKDSLDSQSWSMTQAQLTNDNLQNTMITINALKQTNNA 120
Query: 214 LKGMMKTVKIQDIDNLQDEMMDLMDV-SKIQETLGRSYSVP--DDIDEEELMGELDAL-E 47
+K + I + ++QDEM+DL++ ++QE L + + DDI + EL ELDAL +
Sbjct: 121 MKAQYGKINIDKLQDMQDEMLDLIEQGDELQEVLAMNNNSGELDDISDAELDAELDALAQ 180
Query: 46 ADMGMETESDGV 11
D + T + +
Sbjct: 181 EDFTLPTSENSL 192
>sp|Q9SZE4|VP322_ARATH Vacuolar protein sorting-associated protein 32 homolog 2
OS=Arabidopsis thaliana GN=VPS32.2 PE=2 SV=1
Length = 219
Score = 81 bits (198), Expect = 5e-015
Identities = 50/161 (31%), Positives = 82/161 (50%), Gaps = 2/161 (1%)
Frame = -1
Query: 520 PPSVGDASDRINKRGDTVDEKIKKLDVELNRYKEQIKKTRPGPAQEAVKSRAMRVLKQKR 341
P +A ++K +T++ KK V L + +++K + ++ K A++ LK+KR
Sbjct: 9 PKQEANALQTLDKLNETLEMLEKKEKVLLKKAGAEVEKAKE-YSRAKNKRAAIQCLKRKR 67
Query: 340 MYEGQRDMLYNQTFNLDQVAFASEGIKDAQQTMTALKSANKELKGMMKTVKIQDIDNLQD 161
+YEGQ + L N + EG K +T+ AL+S +K M K I D+D D
Sbjct: 68 LYEGQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVDKTMD 127
Query: 160 EMMDLMD-VSKIQETLGRSYSVPDDIDEEELMGELDALEAD 41
E+ + + + +IQE L D DE+EL ELD LE++
Sbjct: 128 EINEQTENMKQIQEALATPMGAAADFDEDELAAELDELESE 168
>sp|Q6FW96|SNF7_CANGA Vacuolar-sorting protein SNF7 OS=Candida glabrata GN=SNF7
PE=3 SV=1
Length = 228
Score = 60 bits (145), Expect = 7e-009
Identities = 37/111 (33%), Positives = 63/111 (56%), Gaps = 2/111 (1%)
Frame = -1
Query: 376 KSRAMRVLKQKRMYEGQRDMLYNQTFNLDQVAFASEGIKDAQQTMTALKSANKELKGMMK 197
K+ A LK+K++YEGQ L +Q +L+Q F+ E +TM A+K K +K +
Sbjct: 58 KTMAKNALKKKKVYEGQLVKLESQMDSLEQQLFSIESANLNLETMRAMKQGAKAMKSIHS 117
Query: 196 TVKIQDIDNLQDEMMDLMDV-SKIQETLGRS-YSVPDDIDEEELMGELDAL 50
+ I +D DE+ + +++ +I + + R Y+ ++IDE+EL ELD L
Sbjct: 118 GLDIDRVDETMDEIREQVELGEEISDAISRPLYTGANEIDEDELDEELDML 168
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,073,084,167
Number of Sequences: 462764
Number of Extensions: 6073084167
Number of Successful Extensions: 56121479
Number of sequences better than 0.0: 0
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