BLASTX 7.6.2
Query= RU06041 /QuerySize=1936
(1935 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O94889|KLH18_HUMAN Kelch-like protein 18 OS=Homo sapiens GN=K... 75 2e-012
sp|Q6JEL2|KLH10_HUMAN Kelch-like protein 10 OS=Homo sapiens GN=K... 61 3e-008
sp|Q9D5V2|KLH10_MOUSE Kelch-like protein 10 OS=Mus musculus GN=K... 60 6e-008
sp|Q6JEL3|KLH10_RAT Kelch-like protein 10 OS=Rattus norvegicus G... 60 6e-008
sp|Q5EB39|KBTB5_XENTR Kelch repeat and BTB domain-containing pro... 56 7e-007
sp|Q8WZ60|KLHL6_HUMAN Kelch-like protein 6 OS=Homo sapiens GN=KL... 56 9e-007
>sp|O94889|KLH18_HUMAN Kelch-like protein 18 OS=Homo sapiens GN=KLHL18 PE=2
SV=3
Length = 574
Score = 75 bits (182), Expect = 2e-012
Identities = 57/203 (28%), Positives = 97/203 (47%), Gaps = 11/203 (5%)
Frame = +2
Query: 674 VEESPSGDEGANSVDSDWGMDCSTVVRIKTLHISSP--ILAAKSPFFYKLFSNGMRESEQ 847
V E PS G G C ++I S+ +LAA P+F+ +F+N M E +Q
Sbjct: 17 VSELPSRGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQ 76
Query: 848 RHVTLRINASEEAALMELLNFMYSSTLNTTTAPGLLDVLMAADKFEVASCMRHCSRLLRN 1027
+ ++ + +AL L+NF Y+ L + +LM A ++ S C LR
Sbjct: 77 DEIVMQ--GMDPSALEALINFAYNGNL-AIDQQNVQSLLMGASFLQLQSIKDACCTFLRE 133
Query: 1028 IPMTPESALLYLELPSSVLMAEAVQALTDAAKQYLAARYKDISKFIDEVMALPLAGIEAI 1207
+ P++ L + +++ A L DAA ++ + ++S +E +ALPL + +
Sbjct: 134 -RLHPKNCLGVRQFAETMMCA----VLYDAANSFIHQHFVEVS-MSEEFLALPLEDVLEL 187
Query: 1208 VSSDDLQVASEDAVYDFVLKWSR 1276
VS D+L V SE+ V++ L W R
Sbjct: 188 VSRDELNVKSEEQVFEAALAWVR 210
>sp|Q6JEL2|KLH10_HUMAN Kelch-like protein 10 OS=Homo sapiens GN=KLHL10 PE=2
SV=1
Length = 608
Score = 61 bits (146), Expect = 3e-008
Identities = 53/240 (22%), Positives = 109/240 (45%), Gaps = 16/240 (6%)
Frame = +2
Query: 728 GMDCSTVVRIKTLHISS--PILAAKSPFFYKLFSNGMRESEQRHVTLRINASEEAALMEL 901
G C V+++ S+ IL + S +F LF++G +E++ I + +
Sbjct: 36 GKLCDVVIKVNGFEFSAHKNILCSCSSYFRALFTSGWNNTEKK--VYNIPGISPDMMKLI 93
Query: 902 LNFMYSSTLNTTTAPGLLDVLMAADKFEVASCMRHCSRLLRNIPMTPESALLYLELPSSV 1081
+ + Y+ T+ T + +L AAD+F + +R C L++ + ++ + +
Sbjct: 94 IEYAYTRTV-PITPDNVEKLLAAADQFNIMGIVRGCCEFLKS-ELCLDNCIGICKFTDYY 151
Query: 1082 LMAEAVQALTDAAKQYLAARYKDISKFIDEVMALPLAGIEAIVSSDDLQVASEDAVYDFV 1261
E L A ++ ++++ K E + L + ++ I+ D+L V EDAV++ +
Sbjct: 152 YCPE----LRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAI 207
Query: 1262 LKWSRTHYPKLEERREILGSRLARYIRFPYMTCRKLKKVLTCNDF--DHEAASKLVLEAL 1435
LKW +H P + R++ + L + +R M + ND+ D E +++ AL
Sbjct: 208 LKWI-SHDP--QNRKQHISILLPK-VRLALMHAEYFMNNVKMNDYVKDSEECKPVIINAL 263
>sp|Q9D5V2|KLH10_MOUSE Kelch-like protein 10 OS=Mus musculus GN=Klhl10 PE=2
SV=1
Length = 608
Score = 60 bits (143), Expect = 6e-008
Identities = 52/240 (21%), Positives = 109/240 (45%), Gaps = 16/240 (6%)
Frame = +2
Query: 728 GMDCSTVVRIKTLHISS--PILAAKSPFFYKLFSNGMRESEQRHVTLRINASEEAALMEL 901
G C V+++ ++ IL + S +F LF++G +E++ I + +
Sbjct: 36 GKLCDVVIKVNGFEFNAHKNILCSCSSYFRALFTSGWNNTEKK--VYNIPGISPDMMKLI 93
Query: 902 LNFMYSSTLNTTTAPGLLDVLMAADKFEVASCMRHCSRLLRNIPMTPESALLYLELPSSV 1081
+ + Y+ T+ T + +L AAD+F + +R C L++ + ++ + +
Sbjct: 94 IEYAYTRTV-PITPDNVEKLLAAADQFNIMGIVRGCCEFLKS-ELCLDNCIGICKFTDYY 151
Query: 1082 LMAEAVQALTDAAKQYLAARYKDISKFIDEVMALPLAGIEAIVSSDDLQVASEDAVYDFV 1261
E L A ++ ++++ K E + L + ++ I+ D+L V EDAV++ +
Sbjct: 152 YCPE----LRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAI 207
Query: 1262 LKWSRTHYPKLEERREILGSRLARYIRFPYMTCRKLKKVLTCNDF--DHEAASKLVLEAL 1435
LKW +H P + R++ + L + +R M + ND+ D E +++ AL
Sbjct: 208 LKWI-SHDP--QNRKQHISVLLPK-VRLALMHAEYFMNNVKMNDYVKDSEECKPVIINAL 263
>sp|Q6JEL3|KLH10_RAT Kelch-like protein 10 OS=Rattus norvegicus GN=Klhl10 PE=2
SV=1
Length = 608
Score = 60 bits (143), Expect = 6e-008
Identities = 52/240 (21%), Positives = 109/240 (45%), Gaps = 16/240 (6%)
Frame = +2
Query: 728 GMDCSTVVRIKTLHISS--PILAAKSPFFYKLFSNGMRESEQRHVTLRINASEEAALMEL 901
G C V+++ ++ IL + S +F LF++G +E++ I + +
Sbjct: 36 GKLCDVVIKVNGFEFNAHKNILCSCSSYFRALFTSGWNNTEKK--VYNIPGISPDMMKLI 93
Query: 902 LNFMYSSTLNTTTAPGLLDVLMAADKFEVASCMRHCSRLLRNIPMTPESALLYLELPSSV 1081
+ + Y+ T+ T + +L AAD+F + +R C L++ + ++ + +
Sbjct: 94 IEYAYTRTV-PITPDNVEKLLAAADQFNIMGIVRGCCEFLKS-ELCLDNCIGICKFTDYY 151
Query: 1082 LMAEAVQALTDAAKQYLAARYKDISKFIDEVMALPLAGIEAIVSSDDLQVASEDAVYDFV 1261
E L A ++ ++++ K E + L + ++ I+ D+L V EDAV++ +
Sbjct: 152 YCPE----LRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAI 207
Query: 1262 LKWSRTHYPKLEERREILGSRLARYIRFPYMTCRKLKKVLTCNDF--DHEAASKLVLEAL 1435
LKW +H P + R++ + L + +R M + ND+ D E +++ AL
Sbjct: 208 LKWI-SHDP--QNRKQHISVLLPK-VRLALMHAEYFMNNVKMNDYVKDSEECKPVIINAL 263
>sp|Q5EB39|KBTB5_XENTR Kelch repeat and BTB domain-containing protein 5
OS=Xenopus tropicalis GN=kbtbd5 PE=2 SV=1
Length = 614
Score = 56 bits (134), Expect = 7e-007
Identities = 45/188 (23%), Positives = 93/188 (49%), Gaps = 11/188 (5%)
Frame = +2
Query: 713 VDSDWGMDCSTVVRIKTLHISSPILAAKSPFFYKLFSNGMRESEQRHVTLRINASEEAAL 892
+D D +DC ++ K +LAA SP+F +F + + E +++ + L + +
Sbjct: 27 LDHDNFIDCVLKIQGKEFPCHRLVLAACSPYFRAMFLSNLEEGKKKEIDL--EDVDPDVM 84
Query: 893 MELLNFMYSSTLNTTTAPGLLDVLMAADKFEVASCMRHC-SRLLRNIPMTPESALLYLEL 1069
++L+++Y+S + T + D+ A+ F++ S C S L + + ++ A+ L L
Sbjct: 85 GKILHYIYTSEIE-ITEKNVQDIFSVANMFQIPSIFTVCVSFLQKKLCLSNCLAIFRLGL 143
Query: 1070 PSSVLMAEAVQALTDAAKQYLAARYKDISKFIDEVMALPLAGIEAIVSSDDLQVASEDAV 1249
L +A+ ++ R+ I++ +E L + A++SSD L + E+ V
Sbjct: 144 LLD------CPRLAVSARDFVCDRFHLIAR-DEEFYDLSPDELIAVISSDSLNIEKEEEV 196
Query: 1250 YDFVLKWS 1273
++ VLKW+
Sbjct: 197 FEVVLKWA 204
>sp|Q8WZ60|KLHL6_HUMAN Kelch-like protein 6 OS=Homo sapiens GN=KLHL6 PE=2 SV=2
Length = 610
Score = 56 bits (133), Expect = 9e-007
Identities = 47/185 (25%), Positives = 84/185 (45%), Gaps = 10/185 (5%)
Frame = +2
Query: 734 DCSTVVRIKTLHISSPILAAKSPFFYKLFSNGMRESEQRHVTLRINASEEAALMELLNFM 913
D V I+ +LAA S +F +F N ++E ++ + I + + LL++
Sbjct: 62 DVILCVDIQEFSCHRVVLAAASNYFRAMFCNDLKEKYEKRII--IKGVDAETMHTLLDYT 119
Query: 914 YSSTLNTTTAPGLLDVLMAADKFEVASCMRHCSRLLRNIPMTPESALLYLELPSSVLMAE 1093
Y+S T + VL AA+ F+ + C+ L + PE+ + L L +
Sbjct: 120 YTSKA-LITKQNVQRVLEAANLFQFLRMVDACASFLTE-ALNPENCVGILRLADT----H 173
Query: 1094 AVQALTDAAKQYLAARYKDISKFIDEVMALPLAGIEAIVSSDDLQVASEDAVYDFVLKWS 1273
++ +L + Y+ + I +E + LP+ + I+ SDDL V E V++ V+ W
Sbjct: 174 SLDSLKKQVQSYIIQNFVQILN-SEEFLDLPVDTLHHILKSDDLYVTEEAQVFETVMSWV 232
Query: 1274 RTHYP 1288
R H P
Sbjct: 233 R-HKP 236
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,076,592,653
Number of Sequences: 462764
Number of Extensions: 9076592653
Number of Successful Extensions: 89107062
Number of sequences better than 0.0: 0
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