BLASTX 7.6.2
Query= RU06293 /QuerySize=2108
(2107 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6ZNW5|CO058_HUMAN UPF0580 protein C15orf58 OS=Homo sapiens G... 168 2e-040
sp|Q3TLS3|CO058_MOUSE UPF0580 protein C15orf58 homolog OS=Mus mu... 164 3e-039
sp|Q8HXE4|CO058_MACFA UPF0580 protein C15orf58 homolog OS=Macaca... 161 2e-038
sp|Q5E9T1|CO058_BOVIN UPF0580 protein C15orf58 homolog OS=Bos ta... 109 9e-023
sp|Q08CA1|CO058_DANRE UPF0580 protein C15orf58 homolog OS=Danio ... 102 2e-020
sp|Q0V9F1|CO058_XENTR UPF0580 protein C15orf58 homolog OS=Xenopu... 96 8e-019
sp|A8E5Y3|CO058_XENLA UPF0580 protein C15orf58 homolog OS=Xenopu... 96 1e-018
>sp|Q6ZNW5|CO058_HUMAN UPF0580 protein C15orf58 OS=Homo sapiens GN=C15orf58 PE=2
SV=1
Length = 385
Score = 168 bits (423), Expect = 2e-040
Identities = 113/349 (32%), Positives = 177/349 (50%), Gaps = 50/349 (14%)
Frame = +2
Query: 707 PVAFLDSLLLGEWEDRMQKGLFRYDVTACETKVIPGQFGFIAQLNEGRHLKKRPTEFRVD 886
P + D+ L W+ R++ GLFRY + +T+++PG GF+AQLN R +++RP + +
Sbjct: 55 PQSPFDAALCSAWKQRVELGLFRYRLRELQTQILPGAVGFVAQLNVERGVQRRPPQ-TIK 113
Query: 887 KVLQPFDGSKFNFTKVGQEEVLFQFEASEDGEVQFHPNAPIDVENSPSVVAINVSPIEYG 1066
V Q FD +FNF K+ EVLF+ P+ P + +V INVSP+E+G
Sbjct: 114 SVRQAFDPVQFNFNKIRPGEVLFRLHR--------EPDLPGTLLQEDILVVINVSPLEWG 165
Query: 1067 HVLLIPRILESLPQRI-------DRESFLLALHMAAEAGNPYFRLGYNSLGAFATINHLH 1225
HVLL+P LPQR+ E+ LL+LH P FR+G+NSLG A++NHLH
Sbjct: 166 HVLLVPEPARQLPQRLLPGALRAGIEAVLLSLH-------PGFRVGFNSLGGLASVNHLH 218
Query: 1226 FQAYYLAVTFPIEKAPTKKITTLDVGVKISELLNYPVRGLVL---EGGNTLEDLSNSVSD 1396
YYLA P+E+AP++ LD G + L + P G + G LE L + V
Sbjct: 219 LHGYYLAHRLPVEQAPSE---PLDPGGHLHLLQDLPAPGFLFYTRGPGTDLESLISRVCR 275
Query: 1397 ACICLQENNIPYNVLISD-------------CGKRIFLLPQCYAEKQALGEVRAELLDTQ 1537
A L ++ I +N+ ++ G R+ L +A K + G E
Sbjct: 276 ATDYLTDHEIAHNLFVTRGAPPGKTSPSSALIGVRVIL----WARKSSFGIKDGEAF--- 328
Query: 1538 VNPAVWEISGHMVLKRREDYDEASDENAWKLLAEVSLSEERFQEVNALI 1684
N A+ E++GH+ +K +D+ ++ A L+ + L + ++V A +
Sbjct: 329 -NVALCELAGHLPVKTSQDFSSLTEAAAVALIQDCRLPPSQAEDVQAAL 376
>sp|Q3TLS3|CO058_MOUSE UPF0580 protein C15orf58 homolog OS=Mus musculus PE=2
SV=2
Length = 386
Score = 164 bits (413), Expect = 3e-039
Identities = 118/354 (33%), Positives = 176/354 (49%), Gaps = 49/354 (13%)
Frame = +2
Query: 707 PVAFLDSLLLGEWEDRMQKGLFRYDVTACETKVIPGQFGFIAQLNEGRHLKKRPTEFRVD 886
P++ DS L W R++ GLFRY + +T+++PG GF+AQLN R +++R + +
Sbjct: 55 PLSRFDSALRSAWRQRLELGLFRYRLEDLQTQILPGSVGFVAQLNIERGIQRRRPQ-NIR 113
Query: 887 KVLQPFDGSKFNFTKVGQEEVLFQFEASEDGEVQFHPNAPIDVENSPSVVAINVSPIEYG 1066
V Q FD +FNF K+ EVLF+ + G P DV +V INVSP+E+G
Sbjct: 114 SVRQEFDPEQFNFNKIRPGEVLFRMQREPKGPAT--PKQEDDV-----LVVINVSPLEWG 166
Query: 1067 HVLLIPRILESLPQ-------RIDRESFLLALHMAAEAGNPYFRLGYNSLGAFATINHLH 1225
HVLL+P + LPQ R+ E+ LL+LH P FR+G+NSLG A++NHLH
Sbjct: 167 HVLLVPAPAQGLPQRLLPGVLRVGLEAVLLSLH-------PGFRVGFNSLGGLASVNHLH 219
Query: 1226 FQAYYLAVTFPIEKAPTKKITTLDVGVKISELLNYPVRGLVL---EGGNTLEDLSNSVSD 1396
YYLA P+E AP+ T LD I L P G + G LE L + V
Sbjct: 220 LHCYYLAHPLPVEGAPS---TPLDPKGCIHLLQALPAPGFLFYTSGPGPDLEVLISRVCR 276
Query: 1397 ACICLQENNIPYNVLISD-------------CGKRIFLLPQCYAEKQALGEVRAELLDTQ 1537
A L + I +N+ ++ G R+ L +A K + G +
Sbjct: 277 ATDYLSDREIAHNLFVTRGAPPGPTSSTSDLSGIRVIL----WARKSSFGIKESGAF--- 329
Query: 1538 VNPAVWEISGHMVLKRREDYDEASDENAWKLLAEVSLSEERFQEVNALIFGAIA 1699
N A+ E++GH+ +K +D+ ++ A L+ + L E + EV A + +A
Sbjct: 330 -NVALCELAGHLPVKTSQDFSSLTEAAAVALIQDCLLPETQAGEVRAALVALMA 382
>sp|Q8HXE4|CO058_MACFA UPF0580 protein C15orf58 homolog OS=Macaca fascicularis
GN=QflA-20034 PE=2 SV=1
Length = 385
Score = 161 bits (406), Expect = 2e-038
Identities = 112/349 (32%), Positives = 173/349 (49%), Gaps = 50/349 (14%)
Frame = +2
Query: 707 PVAFLDSLLLGEWEDRMQKGLFRYDVTACETKVIPGQFGFIAQLNEGRHLKKRPTEFRVD 886
P + D+ L W+ R++ GLFRY + +T+++PG GF+AQLN R +++R + +
Sbjct: 55 PQSPFDAALCSAWKQRVELGLFRYRLRELQTQILPGVVGFVAQLNVERGVQRRRPQ-TIK 113
Query: 887 KVLQPFDGSKFNFTKVGQEEVLFQFEASEDGEVQFHPNAPIDVENSPSVVAINVSPIEYG 1066
V Q FD +FNF K+ EVL++ P+ P + +V INVSP+E+G
Sbjct: 114 SVRQAFDPEQFNFNKIQPGEVLYRLHR--------EPDLPGTLLQEDILVVINVSPLEWG 165
Query: 1067 HVLLIPRILESLPQRI-------DRESFLLALHMAAEAGNPYFRLGYNSLGAFATINHLH 1225
HVLL+P LPQR+ E+ LL+LH P FR+G+NSLG A++NHLH
Sbjct: 166 HVLLVPEPARGLPQRLLPGALRAGIEAVLLSLH-------PGFRVGFNSLGGLASVNHLH 218
Query: 1226 FQAYYLAVTFPIEKAPTKKITTLDVGVKISELLNYPVRGLVL---EGGNTLEDLSNSVSD 1396
YYLA P+E+AP++ LD G + L P G + G LE L V
Sbjct: 219 LHGYYLAHRLPVEQAPSE---PLDPGGHLHLLQGLPAPGFLFYTRGPGLDLESLICRVCR 275
Query: 1397 ACICLQENNIPYNVLISD-------------CGKRIFLLPQCYAEKQALGEVRAELLDTQ 1537
A L ++ I +N+ ++ G R+ L +A K G E
Sbjct: 276 ATDYLTDHEIAHNLFVTRGAPPGKTSPSSALTGVRVIL----WARKSCFGIKDGEAF--- 328
Query: 1538 VNPAVWEISGHMVLKRREDYDEASDENAWKLLAEVSLSEERFQEVNALI 1684
N A+ E++GH+ +K +D+ ++ A L+ + L + +EV A +
Sbjct: 329 -NVALCELAGHLPVKTSQDFSSLTEAAAVALIQDCRLPPSQAEEVQAAL 376
>sp|Q5E9T1|CO058_BOVIN UPF0580 protein C15orf58 homolog OS=Bos taurus PE=2 SV=1
Length = 385
Score = 109 bits (271), Expect = 9e-023
Identities = 81/266 (30%), Positives = 123/266 (46%), Gaps = 25/266 (9%)
Frame = +2
Query: 953 FQFEASEDGEVQFHPNAPID----VENSPSVVAINVSPIEYGHVLLIPRILESLPQRIDR 1120
F F GEV F + D V+ +V INVSP+E+GHVLL+P LPQR+
Sbjct: 124 FNFNQIRPGEVLFRLHRKQDCSGTVQQEDILVVINVSPLEWGHVLLVPEPARGLPQRLLP 183
Query: 1121 ESFLLALHMAAEAGNPYFRLGYNSLGAFATINHLHFQAYYLAVTFPIEKAPTKKITTLDV 1300
+ + + +P FR+G+NSLG A++NHLH YYLA P+E AP++ LD
Sbjct: 184 GALRAGVEAVLLSSHPGFRVGFNSLGGLASVNHLHLHGYYLAHRLPVEGAPSE---PLDP 240
Query: 1301 GVKISELLNYPVRGLVL---EGGNTLEDLSNSVSDACICLQENNIPYNVLISDCGKRIFL 1471
++ L P G + G LE L + V A L + I +N+ ++
Sbjct: 241 RGRLHVLQALPAPGFLFYTSRPGPDLEALISRVCRATDYLTDCEIAHNLFVTRGAP---- 296
Query: 1472 LPQCYAEKQALGEVRAELLDTQ----------VNPAVWEISGHMVLKRREDYDEASDENA 1621
P AL VR L + N A+ E++GH+ +K +D+ ++ A
Sbjct: 297 -PGKATSSSALSGVRVILWPRKPSFGIKEGEAFNVALCELAGHLPVKTAQDFSSLTEAAA 355
Query: 1622 WKLLAEVSLSEERFQEVNALIFGAIA 1699
L+ E L + ++V A + IA
Sbjct: 356 LALIRECLLPPAQAEDVRAALVALIA 381
Score = 72 bits (174), Expect = 2e-011
Identities = 38/96 (39%), Positives = 55/96 (57%), Gaps = 3/96 (3%)
Frame = +2
Query: 707 PVAFLDSLLLGEWEDRMQKGLFRYDVTACETKVIPGQFGFIAQLNEGRHLKKRPTEFRVD 886
P++ DS L W RM+ GLFRY + T+ +PG GF+AQLN R +++R + +
Sbjct: 55 PLSHFDSALCSAWRQRMELGLFRYPLGELPTQTLPGTVGFVAQLNVERGVQRRCPQ-NIK 113
Query: 887 KVLQPFDGSKFNFTKVGQEEVLFQFEASED--GEVQ 988
V Q FD +FNF ++ EVLF+ +D G VQ
Sbjct: 114 SVRQEFDPEQFNFNQIRPGEVLFRLHRKQDCSGTVQ 149
>sp|Q08CA1|CO058_DANRE UPF0580 protein C15orf58 homolog OS=Danio rerio
GN=zgc:153343 PE=2 SV=1
Length = 343
Score = 102 bits (252), Expect = 2e-020
Identities = 61/215 (28%), Positives = 110/215 (51%), Gaps = 11/215 (5%)
Frame = +2
Query: 1034 VAINVSPIEYGHVLLIPRILESLPQRIDRESFLLALHMAAEAGNPYFRLGYNSLGAFATI 1213
V INVSP+E+GH LL+P + PQ + + + + +P FR+G+NSLG FA++
Sbjct: 120 VIINVSPLEFGHCLLVPEPEKCFPQVLTHLAVQTGIETVLLSADPGFRVGFNSLGGFASV 179
Query: 1214 NHLHFQAYYLAVTFPIEKAPTKKITTLDVGVKISELLNYPVRGLVLEGGNTLEDLSNSVS 1393
NHLH YYL IE +P K + + + EL+++P L G L+ + ++
Sbjct: 180 NHLHLHGYYLNHRLKIESSPAKLVLP---NLNLYELVDFPSGFLFYTQGPNLDLVVKAIC 236
Query: 1394 DACICLQENNIPYNVLISDCGKRIFLLPQCYAEKQALGEVRAELL-------DTQVNPAV 1552
L ++NI +N+ ++ G + P + + + + L ++ N A+
Sbjct: 237 SLTDVLVDHNIAHNLFLTR-GCPPQMEPDTSSSRNGVRVIVWPRLSCFGAKEESAFNVAL 295
Query: 1553 WEISGHMVLKRREDYDEASDENAWKLLAEVSLSEE 1657
E++GH+ K R+DY+ A++E ++ + L +E
Sbjct: 296 CELAGHLPFKNRQDYESATEETVQDIIQKYLLPQE 330
Score = 63 bits (151), Expect = 8e-009
Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 1/85 (1%)
Frame = +2
Query: 722 DSLLLGEWEDRMQKGLFRYDVTACETKVIPGQFGFIAQLNEGRHLKKRPTEFRVDKVLQP 901
D L W ++ GLFRY + ET+++PG G+IAQLN R ++R + + V Q
Sbjct: 32 DIALRSGWTEKRNTGLFRYRLDELETRILPGSRGYIAQLNIMRGTERRKPQ-EILSVRQN 90
Query: 902 FDGSKFNFTKVGQEEVLFQFEASED 976
FD +FNF K+ +E+LF+ + +
Sbjct: 91 FDPKQFNFNKINPKELLFELKRESE 115
>sp|Q0V9F1|CO058_XENTR UPF0580 protein C15orf58 homolog OS=Xenopus tropicalis
PE=2 SV=1
Length = 399
Score = 96 bits (237), Expect = 8e-019
Identities = 62/233 (26%), Positives = 117/233 (50%), Gaps = 17/233 (7%)
Frame = +2
Query: 1007 IDVENSPSVVAINVSPIEYGHVLLIPRILESLPQRIDRESFLLALHMAAEAGNPYFRLGY 1186
++ ++S ++V INVSP+E+GHVL +P LPQ + L + + +P FR+G+
Sbjct: 164 LECKSSCTLVVINVSPLEFGHVLFMPDPSLCLPQILTENLMLFGMESVFLSSHPGFRVGF 223
Query: 1187 NSLGAFATINHLHFQAYYLAVTFPIEKAPTKKITTLDVGVKISELLNYPVRG-LVLEGGN 1363
NSLG FA++NHLH +YL IE + +K + + + ++P G L G
Sbjct: 224 NSLGGFASVNHLHLHGFYLDHELLIESSCSKPLCP---EINFHLVTHFPAPGFLFYTDGK 280
Query: 1364 TLEDLSNSVSDACICLQENNIPYNVLIS-----DCGK----RIFLLPQCYAEKQALGEVR 1516
L+ + + L NI +N+ ++ D GK R + +A K + G
Sbjct: 281 DLKSTAQKICKVTDFLVAKNIAHNLFVTRGSNPDTGKVSEDRNGIRVIIWARKPSFGAKE 340
Query: 1517 AELLDTQVNPAVWEISGHMVLKRREDYDEASDENAWKLLAEVSLSEERFQEVN 1675
+ N A+ E++GH+ +K +ED+ ++++ ++ L+++ F +++
Sbjct: 341 V----SAFNVALCELAGHLPVKNQEDFISITEDSVIAIIHSCLLADDEFTQLS 389
Score = 72 bits (175), Expect = 1e-011
Identities = 39/105 (37%), Positives = 63/105 (60%), Gaps = 6/105 (5%)
Frame = +2
Query: 674 KGFSGHEKQE--APVAFL---DSLLLGEWEDRMQKGLFRYDVTACETKVIPGQFGFIAQL 838
+G S ++QE +FL D L +WE++M +GLFRY + +TK++PG ++AQL
Sbjct: 26 QGLSWKKRQEFAEDTSFLSPFDKALQSKWEEKMNEGLFRYPLRNVQTKILPGSVSYVAQL 85
Query: 839 NEGRHLKKRPTEFRVDKVLQPFDGSKFNFTKVGQEEVLFQFEASE 973
N R + +R E + V Q F+ ++FN+ K+ EE++FQ SE
Sbjct: 86 NIQRSINRRKPE-DIWSVQQKFNPNQFNYNKIKSEEIVFQMIRSE 129
>sp|A8E5Y3|CO058_XENLA UPF0580 protein C15orf58 homolog OS=Xenopus laevis PE=2
SV=1
Length = 399
Score = 96 bits (236), Expect = 1e-018
Identities = 61/233 (26%), Positives = 116/233 (49%), Gaps = 17/233 (7%)
Frame = +2
Query: 1007 IDVENSPSVVAINVSPIEYGHVLLIPRILESLPQRIDRESFLLALHMAAEAGNPYFRLGY 1186
++ + ++V INVSP+E+GHVL +P LPQ + + L L + +P FR+G+
Sbjct: 165 LECKGGCTLVVINVSPLEFGHVLFMPDPSLCLPQILTEDLMLFGLESVLLSAHPGFRVGF 224
Query: 1187 NSLGAFATINHLHFQAYYLAVTFPIEKAPTKKITTLDVGVKISELLNYPVRG-LVLEGGN 1363
NSLG FA++NHLH +YL IE + +K + + + ++P L G
Sbjct: 225 NSLGGFASVNHLHLHGFYLDHDLFIESSSSKPLCP---EMNFHLITHFPAPSFLFYTDGR 281
Query: 1364 TLEDLSNSVSDACICLQENNIPYNVLIS-----DCGK----RIFLLPQCYAEKQALGEVR 1516
L+ + ++ L NI +N+ I+ D G R + +A K + G
Sbjct: 282 NLKSTAQNICKVTDFLVAKNIAHNLFITRGSNPDTGNGSEGRNGIRVNIWARKPSFGAKE 341
Query: 1517 AELLDTQVNPAVWEISGHMVLKRREDYDEASDENAWKLLAEVSLSEERFQEVN 1675
+ N A+ E++GH+ +K +ED++ ++++ ++ L+++ F +++
Sbjct: 342 V----SAFNVALCELAGHLPVKNQEDFNSITEDSVIDIIHNCLLADDEFTQLS 390
Score = 70 bits (169), Expect = 6e-011
Identities = 32/84 (38%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
Frame = +2
Query: 722 DSLLLGEWEDRMQKGLFRYDVTACETKVIPGQFGFIAQLNEGRHLKKRPTEFRVDKVLQP 901
D L +WE +M +GLFRY + +TK++PG ++AQLN R + +R E + + Q
Sbjct: 48 DKALQSKWEQKMNEGLFRYPLRNLQTKILPGSLSYVAQLNIQRSINRRKPE-DIWSIQQK 106
Query: 902 FDGSKFNFTKVGQEEVLFQFEASE 973
F+ ++FN+ K+ EE++FQ SE
Sbjct: 107 FNPNQFNYNKIKPEEIVFQMIRSE 130
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,785,253,344
Number of Sequences: 462764
Number of Extensions: 9785253344
Number of Successful Extensions: 101976155
Number of sequences better than 0.0: 0
|