BLASTX 7.6.2
Query= RU06398 /QuerySize=1131
(1130 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P29136|MEP1_SOYBN Metalloendoproteinase 1 OS=Glycine max PE=1... 119 3e-026
sp|P22757|HE_PARLI Hatching enzyme OS=Paracentrotus lividus PE=1... 86 3e-016
sp|P03956|MMP1_HUMAN Interstitial collagenase OS=Homo sapiens GN... 84 2e-015
sp|P91953|HE_HEMPU 50 kDa hatching enzyme OS=Hemicentrotus pulch... 82 7e-015
sp|O60882|MMP20_HUMAN Matrix metalloproteinase-20 OS=Homo sapien... 82 7e-015
sp|P57748|MMP20_MOUSE Matrix metalloproteinase-20 OS=Mus musculu... 80 2e-014
sp|O18767|MMP20_BOVIN Matrix metalloproteinase-20 OS=Bos taurus ... 80 2e-014
sp|P79287|MMP20_PIG Matrix metalloproteinase-20 OS=Sus scrofa GN... 80 2e-014
sp|P22894|MMP8_HUMAN Neutrophil collagenase OS=Homo sapiens GN=M... 79 4e-014
sp|P21692|MMP1_PIG Interstitial collagenase OS=Sus scrofa GN=MMP... 78 1e-013
sp|P24347|MMP11_HUMAN Stromelysin-3 OS=Homo sapiens GN=MMP11 PE=... 77 2e-013
sp|Q02853|MMP11_MOUSE Stromelysin-3 OS=Mus musculus GN=Mmp11 PE=... 77 2e-013
sp|Q9NRE1|MMP26_HUMAN Matrix metalloproteinase-26 OS=Homo sapien... 77 2e-013
sp|Q9H239|MMP28_HUMAN Matrix metalloproteinase-28 OS=Homo sapien... 77 2e-013
sp|Q9EPL5|MMP1A_MOUSE Interstitial collagenase A OS=Mus musculus... 77 2e-013
sp|Q11005|MMP11_XENLA Stromelysin-3 OS=Xenopus laevis GN=mmp11 P... 76 3e-013
sp|P28053|MMP1_BOVIN Interstitial collagenase OS=Bos taurus GN=M... 76 3e-013
sp|Q499S5|MMP11_RAT Stromelysin-3 OS=Rattus norvegicus GN=Mmp11 ... 76 4e-013
sp|O70138|MMP8_MOUSE Neutrophil collagenase OS=Mus musculus GN=M... 75 7e-013
sp|Q90611|MMP2_CHICK 72 kDa type IV collagenase OS=Gallus gallus... 74 2e-012
sp|O88766|MMP8_RAT Neutrophil collagenase OS=Rattus norvegicus G... 74 2e-012
sp|O13065|MMP18_XENLA Matrix metalloproteinase-18 OS=Xenopus lae... 72 5e-012
sp|Q9XSZ5|MMP1_HORSE Interstitial collagenase OS=Equus caballus ... 69 7e-011
sp|Q5RES1|MMP14_PONAB Matrix metalloproteinase-14 OS=Pongo abeli... 67 1e-010
sp|P39900|MMP12_HUMAN Macrophage metalloelastase OS=Homo sapiens... 66 3e-010
sp|Q63341|MMP12_RAT Macrophage metalloelastase OS=Rattus norvegi... 66 3e-010
sp|P50280|MMP7_RAT Matrilysin OS=Rattus norvegicus GN=Mmp7 PE=2 ... 66 4e-010
sp|P34960|MMP12_MOUSE Macrophage metalloelastase OS=Mus musculus... 64 1e-009
sp|P53690|MMP14_MOUSE Matrix metalloproteinase-14 OS=Mus musculu... 62 5e-009
>sp|P29136|MEP1_SOYBN Metalloendoproteinase 1 OS=Glycine max PE=1 SV=2
Length = 305
Score = 119 bits (298), Expect = 3e-026
Identities = 70/168 (41%), Positives = 88/168 (52%), Gaps = 8/168 (4%)
Frame = -1
Query: 671 FLMEKPKWPSSKYHLSYAFFPGTPSQAT--GAIAQAFATWARSTHFKFSQAQNYQNADVK 498
F + P+W + L+YAF P T AIA+AF+ W + F + +Y+ A++K
Sbjct: 136 FFKDMPRWQAGTTQLTYAFSPEPRLDDTFKSAIARAFSKWTPVVNIAFQETTSYETANIK 195
Query: 497 ISFHRGNHGDGRNFDGPGGVLAHAFYPTDGRFHFDAAENW----SVGAKP--GAYDLESV 336
I F NHGD FDGPGG+L HAF PTDGR HFDA E W V P A+DLESV
Sbjct: 196 ILFASKNHGDPYPFDGPGGILGHAFAPTDGRCHFDADEYWVASGDVTKSPVTSAFDLESV 255
Query: 335 AXXXXXXXXXXXXSSVKGAIMSATISPGVTLKSLHGDDIQGIKALYNV 192
A SS AIM +I P +L DDI GI+ LY +
Sbjct: 256 AVHEIGHLLGLGHSSDLRAIMYPSIPPRTRKVNLAQDDIDGIRKLYGI 303
Score = 64 bits (155), Expect = 1e-009
Identities = 35/83 (42%), Positives = 47/83 (56%), Gaps = 6/83 (7%)
Frame = -3
Query: 969 GDKVKGINDLKKYLHNFGYLNYKNYIHSXXXXXXXXXXXAVKTYQLNFHLKSTGTLDDKT 790
G KG++++K Y H+ GY+ N H A+KTYQ N++L TG D T
Sbjct: 48 GQNYKGLSNVKNYFHHLGYI--PNAPH-FDDNFDDTLVSAIKTYQKNYNLNVTGKFDINT 104
Query: 789 ISQMMMPRCGVPDIV---NGTTS 730
+ Q+M PRCGVPDI+ N TTS
Sbjct: 105 LKQIMTPRCGVPDIIINTNKTTS 127
>sp|P22757|HE_PARLI Hatching enzyme OS=Paracentrotus lividus PE=1 SV=1
Length = 587
Score = 86 bits (212), Expect = 3e-016
Identities = 48/128 (37%), Positives = 67/128 (52%), Gaps = 1/128 (0%)
Frame = -1
Query: 581 IAQAFATWARSTHFKFSQAQNYQNADVKISFHRGNHGDGRNFDGPGGVLAHAFYPTDGRF 402
I +AF W + F + + + D++I F +HGDG +FDG GGVLAHAF P +G
Sbjct: 200 IRRAFRVWDDVSGLSFREVPDTTSVDIRIKFGSYDHGDGISFDGRGGVLAHAFLPRNGDA 259
Query: 401 HFDAAENWSVGAKPGAYDLESVAXXXXXXXXXXXXSSVKGAIMSATISPGVTLKSLHGDD 222
HFD +E W+ G + G +L VA S+V+ A+M V L DD
Sbjct: 260 HFDDSETWTEGTRSGT-NLFQVAAHEFGHSLGLYHSTVRSALMYPYYQGYVPNFRLDNDD 318
Query: 221 IQGIKALY 198
I GI++LY
Sbjct: 319 IAGIRSLY 326
>sp|P03956|MMP1_HUMAN Interstitial collagenase OS=Homo sapiens GN=MMP1 PE=1
SV=3
Length = 469
Score = 84 bits (205), Expect = 2e-015
Identities = 62/162 (38%), Positives = 79/162 (48%), Gaps = 17/162 (10%)
Frame = -1
Query: 656 PKWPSSKYHLSYAFFPGTP----SQATGAIAQAFATWARSTHFKFSQAQNYQNADVKISF 489
P+W + HL+Y TP + AI +AF W+ T F++ Q AD+ ISF
Sbjct: 107 PRWEQT--HLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQ-ADIMISF 163
Query: 488 HRGNHGDGRNFDGPGGVLAHAFYP---TDGRFHFDAAENWSVGAKPGAYDLESVAXXXXX 318
RG+H D FDGPGG LAHAF P G HFD E W+ + Y+L VA
Sbjct: 164 VRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFR--EYNLHRVAAHELG 221
Query: 317 XXXXXXXSSVKGAIM--SATISPGVTLKSLHGDDIQGIKALY 198
S+ GA+M S T S V L DDI GI+A+Y
Sbjct: 222 HSLGLSHSTDIGALMYPSYTFSGDVQLAQ---DDIDGIQAIY 260
>sp|P91953|HE_HEMPU 50 kDa hatching enzyme OS=Hemicentrotus pulcherrimus PE=1
SV=1
Length = 591
Score = 82 bits (200), Expect = 7e-015
Identities = 46/128 (35%), Positives = 64/128 (50%), Gaps = 1/128 (0%)
Frame = -1
Query: 581 IAQAFATWARSTHFKFSQAQNYQNADVKISFHRGNHGDGRNFDGPGGVLAHAFYPTDGRF 402
+ +AF W + F + + + D++I F HGDG +FDG GGVLAHAF P +G
Sbjct: 203 LRRAFQVWDDVSSLTFREVVDSSSVDIRIKFGSYEHGDGISFDGQGGVLAHAFLPRNGDA 262
Query: 401 HFDAAENWSVGAKPGAYDLESVAXXXXXXXXXXXXSSVKGAIMSATISPGVTLKSLHGDD 222
HFD +E W++G G +L VA S V+ A+M +L DD
Sbjct: 263 HFDDSERWTIGTNSGT-NLFQVAAHEFGHSLGLYHSDVQSALMYPYYRGYNPNFNLDRDD 321
Query: 221 IQGIKALY 198
I GI +LY
Sbjct: 322 IAGITSLY 329
>sp|O60882|MMP20_HUMAN Matrix metalloproteinase-20 OS=Homo sapiens GN=MMP20 PE=1
SV=2
Length = 483
Score = 82 bits (200), Expect = 7e-015
Identities = 58/166 (34%), Positives = 81/166 (48%), Gaps = 21/166 (12%)
Frame = -1
Query: 659 KPKWPSSKYHLSYAFFPGTPSQAT----GAIAQAFATWARSTHFKFSQAQNYQNADVKIS 492
+PKW K L+Y TPS ++ A+ A W+ + F + N AD+ IS
Sbjct: 114 EPKW--KKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRI-NSGEADIMIS 170
Query: 491 FHRGNHGDGRNFDGPGGVLAHAFYPTD---GRFHFDAAENWSVGAKPGAYDLESVAXXXX 321
F G+HGD FDGP G LAHAF P + G HFD AE W++G ++L +VA
Sbjct: 171 FENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGT--NGFNLFTVAAHEF 228
Query: 320 XXXXXXXXSSVKGAIMSATISPGVTLKSLHG-----DDIQGIKALY 198
S+ A+M P K+ +G DD++GI+ALY
Sbjct: 229 GHALGLAHSTDPSALM----YPTYKYKNPYGFHLPKDDVKGIQALY 270
>sp|P57748|MMP20_MOUSE Matrix metalloproteinase-20 OS=Mus musculus GN=Mmp20 PE=2
SV=1
Length = 482
Score = 80 bits (197), Expect = 2e-014
Identities = 55/160 (34%), Positives = 78/160 (48%), Gaps = 9/160 (5%)
Frame = -1
Query: 659 KPKWPSS--KYHLSYAFFPGTPSQATGAIAQAFATWARSTHFKFSQAQNYQNADVKISFH 486
+PKW + Y +S +P++ AI A W+ + F + N AD+ ISF
Sbjct: 113 EPKWKKNILTYRISKYTPSMSPTEVDKAIQMALHAWSTAVPLNFVRI-NSGEADIMISFE 171
Query: 485 RGNHGDGRNFDGPGGVLAHAFYPTD---GRFHFDAAENWSVGAKPGAYDLESVAXXXXXX 315
G+HGD FDGP G LAHAF P + G HFD AE W++G ++L +VA
Sbjct: 172 TGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGT--NGFNLFTVAAHEFGH 229
Query: 314 XXXXXXSSVKGAIMSATISPGVTLK-SLHGDDIQGIKALY 198
S+ A+M T + L DD++GI+ALY
Sbjct: 230 ALGLGHSTDPSALMYPTYKYQNPYRFHLPKDDVKGIQALY 269
>sp|O18767|MMP20_BOVIN Matrix metalloproteinase-20 OS=Bos taurus GN=MMP20 PE=1
SV=1
Length = 481
Score = 80 bits (196), Expect = 2e-014
Identities = 55/160 (34%), Positives = 77/160 (48%), Gaps = 9/160 (5%)
Frame = -1
Query: 659 KPKWPSS--KYHLSYAFFPGTPSQATGAIAQAFATWARSTHFKFSQAQNYQNADVKISFH 486
+PKW + Y +S TP++ A+ A W+ + F + N AD+ ISF
Sbjct: 112 EPKWKKNTLTYRISKYTPSMTPAEVDRAMEMALRAWSSAVPLNFVRI-NAGEADIMISFE 170
Query: 485 RGNHGDGRNFDGPGGVLAHAFYPTD---GRFHFDAAENWSVGAKPGAYDLESVAXXXXXX 315
G+HGD FDGP G LAHAF P + G HFD AE W++G ++L +VA
Sbjct: 171 TGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGT--NGFNLFTVAAHEFGH 228
Query: 314 XXXXXXSSVKGAIMSATIS-PGVTLKSLHGDDIQGIKALY 198
S+ A+M T L DD++GI+ALY
Sbjct: 229 ALGLAHSTDPSALMFPTYKYQNPYGFRLPKDDVKGIQALY 268
>sp|P79287|MMP20_PIG Matrix metalloproteinase-20 OS=Sus scrofa GN=MMP20 PE=2
SV=1
Length = 483
Score = 80 bits (196), Expect = 2e-014
Identities = 55/160 (34%), Positives = 77/160 (48%), Gaps = 9/160 (5%)
Frame = -1
Query: 659 KPKWPSS--KYHLSYAFFPGTPSQATGAIAQAFATWARSTHFKFSQAQNYQNADVKISFH 486
+PKW + Y +S TP++ A+ A W+ + F + N AD+ ISF
Sbjct: 114 EPKWKKNTLTYRISKYTPSMTPAEVDKAMEMALQAWSSAVPLSFVRV-NAGEADIMISFE 172
Query: 485 RGNHGDGRNFDGPGGVLAHAFYPTD---GRFHFDAAENWSVGAKPGAYDLESVAXXXXXX 315
G+HGD FDGP G LAHAF P + G HFD AE W++G ++L +VA
Sbjct: 173 TGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGM--NGFNLFTVAAHEFGH 230
Query: 314 XXXXXXSSVKGAIMSATIS-PGVTLKSLHGDDIQGIKALY 198
S+ A+M T L DD++GI+ALY
Sbjct: 231 ALGLAHSTDPSALMYPTYKYQNPYGFHLPKDDVKGIQALY 270
>sp|P22894|MMP8_HUMAN Neutrophil collagenase OS=Homo sapiens GN=MMP8 PE=1 SV=1
Length = 467
Score = 79 bits (194), Expect = 4e-014
Identities = 57/163 (34%), Positives = 81/163 (49%), Gaps = 13/163 (7%)
Frame = -1
Query: 656 PKWPSSKYHLSYAFFPGTP----SQATGAIAQAFATWARSTHFKFSQAQNYQNADVKISF 489
PKW + +L+Y TP ++ AI AF W+ ++ F++ + AD+ I+F
Sbjct: 106 PKW--ERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGE-ADINIAF 162
Query: 488 HRGNHGDGRNFDGPGGVLAHAFYP---TDGRFHFDAAENWSVGAKPGAYDLESVAXXXXX 318
++ +HGD FDGP G+LAHAF P G HFDA E W+ Y+L VA
Sbjct: 163 YQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWT--NTSANYNLFLVAAHEFG 220
Query: 317 XXXXXXXSSVKGAIMSATISPGVTLK-SLHGDDIQGIKALYNV 192
SS GA+M + T SL DDI GI+A+Y +
Sbjct: 221 HSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYGL 263
>sp|P21692|MMP1_PIG Interstitial collagenase OS=Sus scrofa GN=MMP1 PE=1 SV=2
Length = 469
Score = 78 bits (190), Expect = 1e-013
Identities = 59/161 (36%), Positives = 77/161 (47%), Gaps = 15/161 (9%)
Frame = -1
Query: 656 PKWPSSKYHLSYAFFPGTP----SQATGAIAQAFATWARSTHFKFSQAQNYQNADVKISF 489
P+W ++ HL+Y TP AI +AF W+ + F++ Q AD+ ISF
Sbjct: 107 PRWENT--HLTYRIENYTPDLSREDVDRAIEKAFQLWSNVSPLTFTKVSEGQ-ADIMISF 163
Query: 488 HRGNHGDGRNFDGPGGVLAHAFYP---TDGRFHFDAAENWSVGAKPGAYDLESVAXXXXX 318
RG+H D FDGPGG LAHAF P G HFD E W+ + Y+L VA
Sbjct: 164 VRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTKNFRD--YNLYRVAAHELG 221
Query: 317 XXXXXXXSSVKGAIMSAT-ISPGVTLKSLHGDDIQGIKALY 198
S+ GA+M I G L DDI GI+A+Y
Sbjct: 222 HSLGLSHSTDIGALMYPNYIYTGDV--QLSQDDIDGIQAIY 260
>sp|P24347|MMP11_HUMAN Stromelysin-3 OS=Homo sapiens GN=MMP11 PE=1 SV=2
Length = 488
Score = 77 bits (188), Expect = 2e-013
Identities = 50/136 (36%), Positives = 68/136 (50%), Gaps = 6/136 (4%)
Frame = -1
Query: 596 QATGAIAQAFATWARSTHFKFSQAQNYQNADVKISFHRGNHGDGRNFDGPGGVLAHAFYP 417
Q +A+A W+ T F++ AD+ I F R HGD FDGPGG+LAHAF+P
Sbjct: 125 QVRQTMAEALKVWSDVTPLTFTEVHE-GRADIMIDFARYWHGDDLPFDGPGGILAHAFFP 183
Query: 416 ---TDGRFHFDAAENWSVGAKPGAYDLESVAXXXXXXXXXXXXSSVKGAIMSATISPGVT 246
+G HFD E W++G G DL VA ++ A+MSA +
Sbjct: 184 KTHREGDVHFDYDETWTIGDDQGT-DLLQVAAHEFGHVLGLQHTTAAKALMSAFYTFRYP 242
Query: 245 LKSLHGDDIQGIKALY 198
L SL DD +G++ LY
Sbjct: 243 L-SLSPDDCRGVQHLY 257
>sp|Q02853|MMP11_MOUSE Stromelysin-3 OS=Mus musculus GN=Mmp11 PE=1 SV=2
Length = 492
Score = 77 bits (188), Expect = 2e-013
Identities = 50/136 (36%), Positives = 67/136 (49%), Gaps = 6/136 (4%)
Frame = -1
Query: 596 QATGAIAQAFATWARSTHFKFSQAQNYQNADVKISFHRGNHGDGRNFDGPGGVLAHAFYP 417
Q +A+A W+ T F++ AD+ I F R HGD FDGPGG+LAHAF+P
Sbjct: 129 QVRQTVAEALQVWSEVTPLTFTEVHE-GRADIMIDFARYWHGDNLPFDGPGGILAHAFFP 187
Query: 416 ---TDGRFHFDAAENWSVGAKPGAYDLESVAXXXXXXXXXXXXSSVKGAIMSATISPGVT 246
+G HFD E W++G G DL VA ++ A+MS +
Sbjct: 188 KTHREGDVHFDYDETWTIGDNQGT-DLLQVAAHEFGHVLGLQHTTAAKALMSPFYTFRYP 246
Query: 245 LKSLHGDDIQGIKALY 198
L SL DD +GI+ LY
Sbjct: 247 L-SLSPDDRRGIQHLY 261
>sp|Q9NRE1|MMP26_HUMAN Matrix metalloproteinase-26 OS=Homo sapiens GN=MMP26 PE=2
SV=2
Length = 261
Score = 77 bits (188), Expect = 2e-013
Identities = 59/160 (36%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Frame = -1
Query: 653 KWPSSKYHLSYAF--FPG--TPSQATGAIAQAFATWARSTHFKFSQAQNYQNADVKISFH 486
KW +K+ L+Y +P PS +I A + W+ T F Q QN +AD+K+SF
Sbjct: 98 KW--NKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQN-GDADIKVSFW 154
Query: 485 RGNHGDGRNFDGPGGVLAHAFYPTDGR---FHFDAAENWSVGAKPGAYDLESVAXXXXXX 315
+ H DG FDGPGG+L HAF P G HFD E+WS A Y+L VA
Sbjct: 155 QWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWS--ASDTGYNLFLVATHEIGH 212
Query: 314 XXXXXXSSVKGAIMSATI-SPGVTLKSLHGDDIQGIKALY 198
S + +IM T L DDIQ I+ LY
Sbjct: 213 SLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLY 252
>sp|Q9H239|MMP28_HUMAN Matrix metalloproteinase-28 OS=Homo sapiens GN=MMP28 PE=2
SV=2
Length = 520
Score = 77 bits (188), Expect = 2e-013
Identities = 54/164 (32%), Positives = 75/164 (45%), Gaps = 9/164 (5%)
Frame = -1
Query: 671 FLMEKPKWPSSKYHLSYAFF---PGTPSQAT-GAIAQAFATWARSTHFKFSQAQNYQNAD 504
F + KW K HLSY P A GA+ AF W+ + +F +A AD
Sbjct: 123 FAKQGNKW--YKQHLSYRLVNWPEHLPEPAVRGAVRAAFQLWSNVSALEFWEAPATGPAD 180
Query: 503 VKISFHRGNHGD--GRNFDGPGGVLAHAFYPTDGRFHFDAAENWSVGAKPGAYDLESVAX 330
++++F +G+H D G FDGPGG LAHAF P G HFD E WS+ + G +L V
Sbjct: 181 IRLTFFQGDHNDGLGNAFDGPGGALAHAFLPRRGEAHFDQDERWSLSRRRGR-NLFVVLA 239
Query: 329 XXXXXXXXXXXSSVKGAIMSATISPGVTLKSLHGDDIQGIKALY 198
S A+M+ L DD+ +++LY
Sbjct: 240 HEIGHTLGLTHSPAPRALMAPYYKRLGRDALLSWDDVLAVQSLY 283
>sp|Q9EPL5|MMP1A_MOUSE Interstitial collagenase A OS=Mus musculus GN=Mmp1a PE=2
SV=1
Length = 464
Score = 77 bits (187), Expect = 2e-013
Identities = 57/177 (32%), Positives = 80/177 (45%), Gaps = 15/177 (8%)
Frame = -1
Query: 707 GTVQFIPLFTTHFLMEKPKWPSSKYHLSYAFFPGTP----SQATGAIAQAFATWARSTHF 540
G P TH P+W +K HL+Y+ TP + AIA+AF W+ T
Sbjct: 90 GVPDVAPYAITH---NNPRW--TKTHLTYSILNYTPYLPKAVVEDAIARAFRVWSDVTPL 144
Query: 539 KFSQAQNYQNADVKISFHRGNHGDGRNFDGPGGVLAHAFYP---TDGRFHFDAAENWSVG 369
F + + D+ +SFHRG+HGD FDGP LAH F P G H+D E W+
Sbjct: 145 TFQRVFE-EEGDIVLSFHRGDHGDNNPFDGPNYKLAHTFQPGPGLGGDVHYDLDETWTNS 203
Query: 368 AKPGAYDLESVAXXXXXXXXXXXXSSVKGAIMSATISPGVTLKSLHGDDIQGIKALY 198
++ ++L V SS GA+M + + L+ DDI I+ LY
Sbjct: 204 SE--NFNLFYVTAHELGHSLGLTHSSDIGALMFPSYTWYTEDFVLNQDDINRIQDLY 258
>sp|Q11005|MMP11_XENLA Stromelysin-3 OS=Xenopus laevis GN=mmp11 PE=1 SV=1
Length = 477
Score = 76 bits (186), Expect = 3e-013
Identities = 50/131 (38%), Positives = 66/131 (50%), Gaps = 6/131 (4%)
Frame = -1
Query: 581 IAQAFATWARSTHFKFSQAQNYQNADVKISFHRGNHGDGRNFDGPGGVLAHAFYP---TD 411
IA+A W+ T F++ +D+ I F R HGD FDGPGG+LAHAF+P +
Sbjct: 118 IAEALKVWSEVTPLTFTEVHE-GRSDIIIDFTRYWHGDNLPFDGPGGILAHAFFPKTHRE 176
Query: 410 GRFHFDAAENWSVGAKPGAYDLESVAXXXXXXXXXXXXSSVKGAIMSATISPGVTLKSLH 231
G HFD E W++G G DL VA SS+ ++MS + L SL
Sbjct: 177 GDVHFDYDEAWTIGNNIGT-DLLQVAAHEFGHMLGLQHSSISKSLMSPFYTFRYPL-SLS 234
Query: 230 GDDIQGIKALY 198
DD GI+ LY
Sbjct: 235 ADDKHGIQFLY 245
>sp|P28053|MMP1_BOVIN Interstitial collagenase OS=Bos taurus GN=MMP1 PE=1 SV=1
Length = 469
Score = 76 bits (186), Expect = 3e-013
Identities = 55/134 (41%), Positives = 68/134 (50%), Gaps = 11/134 (8%)
Frame = -1
Query: 584 AIAQAFATWARSTHFKFSQAQNYQNADVKISFHRGNHGDGRNFDGPGGVLAHAFYP---T 414
AI +AF W+ T F++ Q AD+ ISF RG+H D FDGPGG LAHAF P
Sbjct: 133 AIEKAFQLWSNVTPLTFTKVSEGQ-ADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGAGI 191
Query: 413 DGRFHFDAAENWSVGAKPGAYDLESVAXXXXXXXXXXXXSSVKGAIM--SATISPGVTLK 240
G HFD E W+ + Y+L VA S+ GA+M S T S V L
Sbjct: 192 GGDAHFDDDEWWTSNFQD--YNLYRVAAHEFGHSLGLAHSTDIGALMYPSYTFSGDVQLS 249
Query: 239 SLHGDDIQGIKALY 198
DDI GI+A+Y
Sbjct: 250 Q---DDIDGIQAIY 260
>sp|Q499S5|MMP11_RAT Stromelysin-3 OS=Rattus norvegicus GN=Mmp11 PE=1 SV=1
Length = 491
Score = 76 bits (185), Expect = 4e-013
Identities = 50/136 (36%), Positives = 67/136 (49%), Gaps = 7/136 (5%)
Frame = -1
Query: 596 QATGAIAQAFATWARSTHFKFSQAQNYQNADVKISFHRGNHGDGRNFDGPGGVLAHAFYP 417
Q +A+A W+ T F++ AD+ I F R HGD FDGPGG+LAHAF+P
Sbjct: 129 QVRQTVAEALRVWSEVTPLTFTEVHE-GRADIMIDFTRYWHGDNLPFDGPGGILAHAFFP 187
Query: 416 ---TDGRFHFDAAENWSVGAKPGAYDLESVAXXXXXXXXXXXXSSVKGAIMSATISPGVT 246
+G HFD E W++G K DL VA ++ A+MS +
Sbjct: 188 KTHREGDVHFDYDETWTIGDK--GTDLLQVAAHEFGHVLGLQHTTAAKALMSPFYTFRYP 245
Query: 245 LKSLHGDDIQGIKALY 198
L SL DD +GI+ LY
Sbjct: 246 L-SLSPDDRRGIQHLY 260
>sp|O70138|MMP8_MOUSE Neutrophil collagenase OS=Mus musculus GN=Mmp8 PE=2 SV=1
Length = 465
Score = 75 bits (183), Expect = 7e-013
Identities = 54/161 (33%), Positives = 80/161 (49%), Gaps = 13/161 (8%)
Frame = -1
Query: 656 PKWPSSKYHLSYAFFPGTP----SQATGAIAQAFATWARSTHFKFSQAQNYQNADVKISF 489
PKW + +L+Y TP ++ AI +AF W+ ++ F++ + AD+ I+F
Sbjct: 106 PKWTHT--NLTYWIINHTPQLSRAEVKTAIEKAFHVWSVASPLTFTEILQGE-ADINIAF 162
Query: 488 HRGNHGDGRNFDGPGGVLAHAFYP---TDGRFHFDAAENWSVGAKPGAYDLESVAXXXXX 318
+HGD FDGP G+LAHAF P G HFD+ E W+ +K Y+L VA
Sbjct: 163 VSRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDSEETWTQDSK--NYNLFLVAAHEFG 220
Query: 317 XXXXXXXSSVKGAIMSATIS-PGVTLKSLHGDDIQGIKALY 198
S+ GA+M + + SL DDI GI+ +Y
Sbjct: 221 HSLGLSHSTDPGALMYPNYAYREPSTYSLPQDDINGIQTIY 261
>sp|Q90611|MMP2_CHICK 72 kDa type IV collagenase OS=Gallus gallus GN=MMP2 PE=1
SV=1
Length = 663
Score = 74 bits (179), Expect = 2e-012
Identities = 44/109 (40%), Positives = 57/109 (52%), Gaps = 10/109 (9%)
Frame = -1
Query: 674 HFLMEKPKWPSSKYHLSYAFFPGT----PSQATGAIAQAFATWARSTHFKFSQAQNYQNA 507
+F KPKW K H++Y T P A A+AF W+ T +F++ N A
Sbjct: 108 NFFPRKPKW--EKNHITYRIIGYTPDLDPETVDDAFARAFKVWSDVTPLRFNRI-NDGEA 164
Query: 506 DVKISFHRGNHGDGRNFDGPGGVLAHAFYP---TDGRFHFDAAENWSVG 369
D+ I+F R HGDG FDG G+LAHAF P G HFD E W++G
Sbjct: 165 DIMINFGRWEHGDGYPFDGKDGLLAHAFAPGPGIGGDSHFDDDELWTLG 213
>sp|O88766|MMP8_RAT Neutrophil collagenase OS=Rattus norvegicus GN=Mmp8 PE=2
SV=1
Length = 466
Score = 74 bits (179), Expect = 2e-012
Identities = 53/161 (32%), Positives = 78/161 (48%), Gaps = 13/161 (8%)
Frame = -1
Query: 656 PKWPSSKYHLSYAFFPGTP----SQATGAIAQAFATWARSTHFKFSQAQNYQNADVKISF 489
PKW + +L+Y TP ++ I +AF W+ + F++ + AD+ I+F
Sbjct: 107 PKWTHT--NLTYRIINHTPQMSKAEVKTEIEKAFKIWSVPSTLTFTETLEGE-ADINIAF 163
Query: 488 HRGNHGDGRNFDGPGGVLAHAFYP---TDGRFHFDAAENWSVGAKPGAYDLESVAXXXXX 318
+HGD FDGP G+LAHAF P G HFD+ E W+ +K Y+L VA
Sbjct: 164 VSRDHGDNSPFDGPNGILAHAFQPGRGIGGDAHFDSEETWTQDSK--NYNLFLVAAHEFG 221
Query: 317 XXXXXXXSSVKGAIMSATIS-PGVTLKSLHGDDIQGIKALY 198
S+ GA+M + + SL DDI GI+ +Y
Sbjct: 222 HSLGLSHSTDPGALMYPNYAYREPSTYSLPQDDINGIQTIY 262
>sp|O13065|MMP18_XENLA Matrix metalloproteinase-18 OS=Xenopus laevis GN=mmp18
PE=2 SV=1
Length = 467
Score = 72 bits (176), Expect = 5e-012
Identities = 54/155 (34%), Positives = 75/155 (48%), Gaps = 11/155 (7%)
Frame = -1
Query: 638 KYHLSYAFFPGTP----SQATGAIAQAFATWARSTHFKFSQAQNYQNADVKISFHRGNHG 471
K L+Y TP + AI +AF W+ T F++ N + +D++ISF G+H
Sbjct: 111 KKDLTYRILNFTPDLPQADVETAIQRAFKVWSDVTPLTFTRIYN-EVSDIEISFTAGDHK 169
Query: 470 DGRNFDGPGGVLAHAFYPTD---GRFHFDAAENWSVGAKPGAYDLESVAXXXXXXXXXXX 300
D FDG GG+LAHAF P + G HFD E W+ ++ Y+L VA
Sbjct: 170 DNSPFDGSGGILAHAFQPGNGIGGDAHFDEDETWTKTSE--IYNLFLVAAHEFGHSLGLS 227
Query: 299 XSSVKGAIMSATIS-PGVTLKSLHGDDIQGIKALY 198
S+ +GA+M T S L DDI I+ LY
Sbjct: 228 HSTDQGALMYPTYSNTDPKTFQLPQDDINAIQYLY 262
>sp|Q9XSZ5|MMP1_HORSE Interstitial collagenase OS=Equus caballus GN=MMP1 PE=2
SV=1
Length = 469
Score = 69 bits (166), Expect = 7e-011
Identities = 41/101 (40%), Positives = 54/101 (53%), Gaps = 10/101 (9%)
Frame = -1
Query: 656 PKWPSSKYHLSYAFFPGTP----SQATGAIAQAFATWARSTHFKFSQAQNYQNADVKISF 489
P+W ++ HL+Y TP + AI +AF W+ + F++ Q AD+ ISF
Sbjct: 107 PRWENT--HLTYRIENYTPDLPRADVDQAIEKAFQLWSNVSPLTFTKVSEGQ-ADIMISF 163
Query: 488 HRGNHGDGRNFDGPGGVLAHAFYP---TDGRFHFDAAENWS 375
RG+H D FDGPGG LAHAF P G HFD E W+
Sbjct: 164 VRGDHRDNSPFDGPGGNLAHAFQPGPRIGGDAHFDEDETWT 204
>sp|Q5RES1|MMP14_PONAB Matrix metalloproteinase-14 OS=Pongo abelii GN=MMP14 PE=2
SV=1
Length = 582
Score = 67 bits (163), Expect = 1e-010
Identities = 51/141 (36%), Positives = 66/141 (46%), Gaps = 12/141 (8%)
Frame = -1
Query: 584 AIAQAFATWARSTHFKFSQAQ-------NYQNADVKISFHRGNHGDGRNFDGPGGVLAHA 426
AI +AF W +T +F + + + ADV I F G HGD FDG GG LAHA
Sbjct: 143 AIRKAFRVWESATPLRFREVPYAYIREGHEKQADVMIFFAEGFHGDSTPFDGEGGFLAHA 202
Query: 425 FYP---TDGRFHFDAAENWSVGAKP-GAYDLESVAXXXXXXXXXXXXSSVKGAIMSATIS 258
++P G HFD+AE W+VG + D+ VA SS AIM+
Sbjct: 203 YFPGPNIGGDTHFDSAEPWTVGNEDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQ 262
Query: 257 PGVTLK-SLHGDDIQGIKALY 198
T L DD +GI+ LY
Sbjct: 263 WMDTENFVLPEDDRRGIQQLY 283
>sp|P39900|MMP12_HUMAN Macrophage metalloelastase OS=Homo sapiens GN=MMP12 PE=1
SV=1
Length = 470
Score = 66 bits (160), Expect = 3e-010
Identities = 43/108 (39%), Positives = 54/108 (50%), Gaps = 9/108 (8%)
Frame = -1
Query: 674 HFLMEKPKWPS-SKYHLSYAFFPGTP----SQATGAIAQAFATWARSTHFKFSQAQNYQN 510
H E P P K++++Y TP AI +AF W+ T KFS+ N
Sbjct: 98 HHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKI-NTGM 156
Query: 509 ADVKISFHRGNHGDGRNFDGPGGVLAHAFYP---TDGRFHFDAAENWS 375
AD+ + F RG HGD FDG GG+LAHAF P G HFD E W+
Sbjct: 157 ADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWT 204
>sp|Q63341|MMP12_RAT Macrophage metalloelastase OS=Rattus norvegicus GN=Mmp12
PE=2 SV=1
Length = 465
Score = 66 bits (160), Expect = 3e-010
Identities = 38/103 (36%), Positives = 54/103 (52%), Gaps = 10/103 (9%)
Frame = -1
Query: 662 EKPKWPSSKYHLSYAFFPGTPSQATGAI----AQAFATWARSTHFKFSQAQNYQNADVKI 495
++ +W K +L+Y + TP + +AF W+ T +F + + AD+ I
Sbjct: 101 QRSRW--MKRYLTYRIYNYTPDMKRADVDYIFQKAFQVWSDVTPLRFRKIHKGE-ADITI 157
Query: 494 SFHRGNHGDGRNFDGPGGVLAHAFYP---TDGRFHFDAAENWS 375
F G+HGD +FDG GG LAHAFYP G HFD AE W+
Sbjct: 158 LFAFGDHGDFYDFDGKGGTLAHAFYPGPGIQGDAHFDEAETWT 200
>sp|P50280|MMP7_RAT Matrilysin OS=Rattus norvegicus GN=Mmp7 PE=2 SV=1
Length = 267
Score = 66 bits (159), Expect = 4e-010
Identities = 47/132 (35%), Positives = 60/132 (45%), Gaps = 6/132 (4%)
Frame = -1
Query: 581 IAQAFATWARSTHFKFSQAQNYQNADVKISFHRGNHGDGRNFDGPGGVLAHAFYP---TD 411
+ +A W+ F + ++ AD+ I F RG+HGD FDGPG L HAF P
Sbjct: 132 VKRALRMWSMQIPLNFKRV-SWGTADIIIGFARGDHGDNFPFDGPGNTLGHAFAPGPGLG 190
Query: 410 GRFHFDAAENWSVGAKPGAYDLESVAXXXXXXXXXXXXSSVKGAIMSATISPGVTLK-SL 234
G HFD E W+ G G L VA SSV ++M T + SL
Sbjct: 191 GDAHFDKDEYWTDGEDSGVNFL-FVATHELGHSLGLGHSSVPSSVMYPTYQGDHSEDFSL 249
Query: 233 HGDDIQGIKALY 198
DDI GI+ LY
Sbjct: 250 TKDDIAGIQKLY 261
>sp|P34960|MMP12_MOUSE Macrophage metalloelastase OS=Mus musculus GN=Mmp12 PE=1
SV=3
Length = 473
Score = 64 bits (155), Expect = 1e-009
Identities = 38/103 (36%), Positives = 51/103 (49%), Gaps = 10/103 (9%)
Frame = -1
Query: 662 EKPKWPSSKYHLSYAFFPGTPSQATGAI----AQAFATWARSTHFKFSQAQNYQNADVKI 495
++ +W K +L+Y + TP + +AF W+ T +F + AD+ I
Sbjct: 109 QRSRW--MKRYLTYRIYNYTPDMKREDVDYIFQKAFQVWSDVTPLRFRKLHK-DEADIMI 165
Query: 494 SFHRGNHGDGRNFDGPGGVLAHAFYP---TDGRFHFDAAENWS 375
F G HGD FDG GG LAHAFYP G HFD AE W+
Sbjct: 166 LFAFGAHGDFNYFDGKGGTLAHAFYPGPGIQGDAHFDEAETWT 208
>sp|P53690|MMP14_MOUSE Matrix metalloproteinase-14 OS=Mus musculus GN=Mmp14 PE=2
SV=2
Length = 582
Score = 62 bits (150), Expect = 5e-009
Identities = 42/131 (32%), Positives = 60/131 (45%), Gaps = 12/131 (9%)
Frame = -1
Query: 728 CDQPRSTGTVQFIPLFTTHFLMEKPKWPSSKYHLSYA-FFPGTPSQAT-GAIAQAFATWA 555
C P GT + + ++ KW ++ + P AT AI +AF W
Sbjct: 93 CGVPDKFGTEIKANVRRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATFEAIRKAFRVWE 152
Query: 554 RSTHFKFSQAQ-------NYQNADVKISFHRGNHGDGRNFDGPGGVLAHAFYP---TDGR 405
+T +F + + + AD+ I F G HGD FDG GG LAHA++P G
Sbjct: 153 SATPLRFREVPYAYIREGHEKQADIMILFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGD 212
Query: 404 FHFDAAENWSV 372
HFD+AE W+V
Sbjct: 213 THFDSAEPWTV 223
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,127,968,007
Number of Sequences: 462764
Number of Extensions: 10127968007
Number of Successful Extensions: 107429881
Number of sequences better than 0.0: 0
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