BLASTX 7.6.2
Query= RU10475 /QuerySize=578
(577 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O48686|SIN3_ARATH Paired amphipathic helix protein Sin3 OS=Ar... 190 8e-048
sp|Q96ST3|SIN3A_HUMAN Paired amphipathic helix protein Sin3a OS=... 82 2e-015
sp|Q60520|SIN3A_MOUSE Paired amphipathic helix protein Sin3a OS=... 82 2e-015
sp|Q62141|SIN3B_MOUSE Paired amphipathic helix protein Sin3b OS=... 80 5e-015
sp|O75182|SIN3B_HUMAN Paired amphipathic helix protein Sin3b OS=... 79 1e-014
sp|P22579|SIN3_YEAST Transcriptional regulatory protein SIN3 OS=... 73 1e-012
sp|Q09750|PST1_SCHPO Paired amphipathic helix protein pst1 OS=Sc... 72 3e-012
sp|O13919|PST2_SCHPO Paired amphipathic helix protein pst2 OS=Sc... 64 5e-010
>sp|O48686|SIN3_ARATH Paired amphipathic helix protein Sin3 OS=Arabidopsis
thaliana GN=SIN3 PE=1 SV=2
Length = 1353
Score = 190 bits (480), Expect = 8e-048
Identities = 91/130 (70%), Positives = 106/130 (81%)
Frame = -3
Query: 566 LLAKEQNLGLKY*NDHWVSVTSGSEDYSFKHMRKNQYEESLFRCEDDRFELDMLLESVNV 387
+ +++ +G NDHWVSVTSGSEDYSF HMRKNQYEESLF+CEDDRFELDMLLESVN
Sbjct: 468 IASQKTEIGKLVLNDHWVSVTSGSEDYSFSHMRKNQYEESLFKCEDDRFELDMLLESVNS 527
Query: 386 TTKRVEELLEKINNNTIKTESPIRVEEYFTALNLRCVERLYGDHGLDVMDVLRKKCSTSF 207
TTK VEELL KIN+N +KT SPIRVE++ TALNLRC+ERLYGDHGLDVMDVL+K S +
Sbjct: 528 TTKHVEELLTKINSNELKTNSPIRVEDHLTALNLRCIERLYGDHGLDVMDVLKKNVSLAL 587
Query: 206 ACYINALEAK 177
+ L+ K
Sbjct: 588 PVILTRLKQK 597
Score = 138 bits (346), Expect = 3e-032
Identities = 66/75 (88%), Positives = 71/75 (94%)
Frame = -1
Query: 226 KNAPLALPVILTRLKQKQEEWARCRSDFNKVWADIYAKNYHKSLDHRSFYFKQQDSKSLS 47
KN LALPVILTRLKQKQEEWARCRSDF+KVWA+IYAKNY+KSLDHRSFYFKQQDSK LS
Sbjct: 581 KNVSLALPVILTRLKQKQEEWARCRSDFDKVWAEIYAKNYYKSLDHRSFYFKQQDSKKLS 640
Query: 46 TKALLAEIKEMSEKK 2
KALLAEIKE++EKK
Sbjct: 641 MKALLAEIKEITEKK 655
>sp|Q96ST3|SIN3A_HUMAN Paired amphipathic helix protein Sin3a OS=Homo sapiens
GN=SIN3A PE=1 SV=2
Length = 1273
Score = 82 bits (201), Expect = 2e-015
Identities = 41/121 (33%), Positives = 72/121 (59%), Gaps = 4/121 (3%)
Frame = -3
Query: 527 NDHWVSVTSGSEDYSFKHMRKNQYEESLFRCEDDRFELDMLLESVNVTTKRVEELLEKIN 348
ND WVS S SED +F +K QYEE ++RCED+RFELD++LE+ T + +E + +K++
Sbjct: 582 NDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLS 641
Query: 347 NNTIKTESPIRVEEYF----TALNLRCVERLYGDHGLDVMDVLRKKCSTSFACYINALEA 180
+ + ++ R++ ++ + ++R+Y D D++D LRK S + + L+
Sbjct: 642 RLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKM 701
Query: 179 K 177
K
Sbjct: 702 K 702
Score = 77 bits (188), Expect = 6e-014
Identities = 35/75 (46%), Positives = 51/75 (68%)
Frame = -1
Query: 226 KNAPLALPVILTRLKQKQEEWARCRSDFNKVWADIYAKNYHKSLDHRSFYFKQQDSKSLS 47
KN +A+P++L RLK K+EEW + FNKVW + K Y KSLDH+ FKQ D+K L
Sbjct: 686 KNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLR 745
Query: 46 TKALLAEIKEMSEKK 2
+K+LL EI+ + +++
Sbjct: 746 SKSLLNEIESIYDER 760
>sp|Q60520|SIN3A_MOUSE Paired amphipathic helix protein Sin3a OS=Mus musculus
GN=Sin3a PE=1 SV=2
Length = 1282
Score = 82 bits (201), Expect = 2e-015
Identities = 41/121 (33%), Positives = 72/121 (59%), Gaps = 4/121 (3%)
Frame = -3
Query: 527 NDHWVSVTSGSEDYSFKHMRKNQYEESLFRCEDDRFELDMLLESVNVTTKRVEELLEKIN 348
ND WVS S SED +F +K QYEE ++RCED+RFELD++LE+ T + +E + +K++
Sbjct: 583 NDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLS 642
Query: 347 NNTIKTESPIRVEEYF----TALNLRCVERLYGDHGLDVMDVLRKKCSTSFACYINALEA 180
+ + ++ R++ ++ + ++R+Y D D++D LRK S + + L+
Sbjct: 643 RLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKM 702
Query: 179 K 177
K
Sbjct: 703 K 703
Score = 77 bits (188), Expect = 6e-014
Identities = 35/75 (46%), Positives = 51/75 (68%)
Frame = -1
Query: 226 KNAPLALPVILTRLKQKQEEWARCRSDFNKVWADIYAKNYHKSLDHRSFYFKQQDSKSLS 47
KN +A+P++L RLK K+EEW + FNKVW + K Y KSLDH+ FKQ D+K L
Sbjct: 687 KNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLR 746
Query: 46 TKALLAEIKEMSEKK 2
+K+LL EI+ + +++
Sbjct: 747 SKSLLNEIESIYDER 761
>sp|Q62141|SIN3B_MOUSE Paired amphipathic helix protein Sin3b OS=Mus musculus
GN=Sin3b PE=1 SV=2
Length = 1098
Score = 80 bits (197), Expect = 5e-015
Identities = 41/121 (33%), Positives = 71/121 (58%), Gaps = 4/121 (3%)
Frame = -3
Query: 527 NDHWVSVTSGSEDYSFKHMRKNQYEESLFRCEDDRFELDMLLESVNVTTKRVEELLEKIN 348
ND WVS S SED +F +K YEE L RCED+RFELD++LE+ T + +E + +K++
Sbjct: 416 NDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLS 475
Query: 347 NNTIKTESPIRVEEYF----TALNLRCVERLYGDHGLDVMDVLRKKCSTSFACYINALEA 180
+ + +R+++ + R + R+YGD +V++ L++ +T+ + L+A
Sbjct: 476 RMAPEDQEKLRLDDCLGGTSEVIQRRAIHRIYGDKAPEVIESLKRNPATAVPVVLKRLKA 535
Query: 179 K 177
K
Sbjct: 536 K 536
Score = 79 bits (192), Expect = 2e-014
Identities = 35/74 (47%), Positives = 52/74 (70%)
Frame = -1
Query: 226 KNAPLALPVILTRLKQKQEEWARCRSDFNKVWADIYAKNYHKSLDHRSFYFKQQDSKSLS 47
+N A+PV+L RLK K+EEW + FNK+W + Y K Y KSLDH++ FKQ D+K+L
Sbjct: 520 RNPATAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALR 579
Query: 46 TKALLAEIKEMSEK 5
+K+LL EI+ + ++
Sbjct: 580 SKSLLNEIESVYDE 593
>sp|O75182|SIN3B_HUMAN Paired amphipathic helix protein Sin3b OS=Homo sapiens
GN=SIN3B PE=1 SV=2
Length = 1162
Score = 79 bits (194), Expect = 1e-014
Identities = 36/74 (48%), Positives = 52/74 (70%)
Frame = -1
Query: 226 KNAPLALPVILTRLKQKQEEWARCRSDFNKVWADIYAKNYHKSLDHRSFYFKQQDSKSLS 47
KN A+PV+L RLK K+EEW + FNK+W + Y K Y KSLDH++ FKQ D+K+L
Sbjct: 561 KNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALR 620
Query: 46 TKALLAEIKEMSEK 5
+K+LL EI+ + ++
Sbjct: 621 SKSLLNEIESVYDE 634
Score = 79 bits (192), Expect = 2e-014
Identities = 41/121 (33%), Positives = 69/121 (57%), Gaps = 4/121 (3%)
Frame = -3
Query: 527 NDHWVSVTSGSEDYSFKHMRKNQYEESLFRCEDDRFELDMLLESVNVTTKRVEELLEKIN 348
ND WVS S SED +F +K YEE L RCED+RFELD++LE+ T + +E + +K++
Sbjct: 457 NDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLS 516
Query: 347 NNTIKTESPIRVEEYF----TALNLRCVERLYGDHGLDVMDVLRKKCSTSFACYINALEA 180
+ + R+++ + R + R+YGD ++++ L+K T+ + L+A
Sbjct: 517 RMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKA 576
Query: 179 K 177
K
Sbjct: 577 K 577
>sp|P22579|SIN3_YEAST Transcriptional regulatory protein SIN3 OS=Saccharomyces
cerevisiae GN=SIN3 PE=1 SV=2
Length = 1536
Score = 73 bits (177), Expect = 1e-012
Identities = 33/64 (51%), Positives = 44/64 (68%)
Frame = -1
Query: 205 PVILTRLKQKQEEWARCRSDFNKVWADIYAKNYHKSLDHRSFYFKQQDSKSLSTKALLAE 26
PV+L RLKQK EEW R + ++NKVW ++ K + KSLDH FKQ D K L+TK L++E
Sbjct: 892 PVVLKRLKQKDEEWRRAQREWNKVWRELEQKVFFKSLDHLGLTFKQADKKLLTTKQLISE 951
Query: 25 IKEM 14
I +
Sbjct: 952 ISSI 955
Score = 55 bits (131), Expect = 2e-007
Identities = 36/123 (29%), Positives = 65/123 (52%), Gaps = 6/123 (4%)
Frame = -3
Query: 527 NDHWVS-VTSGSEDYSFKHMRKNQYEESLFRCEDDRFELDMLLESVNVTTKRVEELLEKI 351
ND WV SED F RKNQYEE+LF+ E++R E D +ES T + +E ++ KI
Sbjct: 779 NDEWVGHPVWASEDSGFIAHRKNQYEETLFKIEEERHEYDFYIESNLRTIQCLETIVNKI 838
Query: 350 NNNTIKTESPIRVEEYF--TALNL--RCVERLYG-DHGLDVMDVLRKKCSTSFACYINAL 186
N T ++ ++ T++ + + + ++Y + G +++D L + + + + L
Sbjct: 839 ENMTENEKANFKLPPGLGHTSMTIYKKVIRKVYDKERGFEIIDALHEHPAVTAPVVLKRL 898
Query: 185 EAK 177
+ K
Sbjct: 899 KQK 901
>sp|Q09750|PST1_SCHPO Paired amphipathic helix protein pst1
OS=Schizosaccharomyces pombe GN=pst1 PE=1 SV=1
Length = 1522
Score = 72 bits (174), Expect = 3e-012
Identities = 28/75 (37%), Positives = 52/75 (69%)
Frame = -1
Query: 226 KNAPLALPVILTRLKQKQEEWARCRSDFNKVWADIYAKNYHKSLDHRSFYFKQQDSKSLS 47
KN + +P++L RLK+K EW ++ +N++W DI KN+++SLDH+ FK D KS +
Sbjct: 730 KNPSVTIPIVLERLKKKDREWRSLQNHWNELWHDIEEKNFYRSLDHQGVSFKSVDKKSTT 789
Query: 46 TKALLAEIKEMSEKK 2
K L++E++ +++++
Sbjct: 790 PKFLISELRNLAQQQ 804
>sp|O13919|PST2_SCHPO Paired amphipathic helix protein pst2
OS=Schizosaccharomyces pombe GN=pst2 PE=1 SV=1
Length = 1075
Score = 64 bits (154), Expect = 5e-010
Identities = 29/63 (46%), Positives = 41/63 (65%)
Frame = -1
Query: 214 LALPVILTRLKQKQEEWARCRSDFNKVWADIYAKNYHKSLDHRSFYFKQQDSKSLSTKAL 35
L LP++++RL++K EEW + W I KNY KSLD + YFK +D K++S+K L
Sbjct: 475 LTLPLVISRLEEKNEEWKSVKRSLQPGWRSIEFKNYDKSLDSQCVYFKARDKKNVSSKFL 534
Query: 34 LAE 26
LAE
Sbjct: 535 LAE 537
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,192,140,658
Number of Sequences: 462764
Number of Extensions: 15192140658
Number of Successful Extensions: 146257600
Number of sequences better than 0.0: 0
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