BLASTX 7.6.2
Query= RU12348 /QuerySize=470
(469 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O82175|SUVH5_ARATH Histone-lysine N-methyltransferase, H3 lys... 145 1e-034
sp|Q8VZ17|SUVH6_ARATH Histone-lysine N-methyltransferase, H3 lys... 131 2e-030
sp|Q9T0G7|SUVH9_ARATH Probable histone-lysine N-methyltransferas... 104 2e-022
sp|Q93YF5|SUVH1_TOBAC Histone-lysine N-methyltransferase, H3 lys... 98 2e-020
sp|Q9C5P4|SUVH3_ARATH Histone-lysine N-methyltransferase, H3 lys... 98 2e-020
sp|Q8GZB6|SUVH4_ARATH Histone-lysine N-methyltransferase, H3 lys... 95 2e-019
sp|O22781|SUVH2_ARATH Histone-lysine N-methyltransferase, H3 lys... 93 5e-019
sp|Q9FF80|SUVH1_ARATH Histone-lysine N-methyltransferase, H3 lys... 93 7e-019
sp|Q9C5P1|SUVH7_ARATH Histone-lysine N-methyltransferase, H3 lys... 83 5e-016
sp|Q9Z148|EHMT2_MOUSE Histone-lysine N-methyltransferase, H3 lys... 65 1e-010
sp|Q9H9B1|EHMT1_HUMAN Histone-lysine N-methyltransferase, H3 lys... 64 3e-010
sp|Q96KQ7|EHMT2_HUMAN Histone-lysine N-methyltransferase, H3 lys... 64 3e-010
sp|O60016|CLR4_SCHPO Histone-lysine N-methyltransferase, H3 lysi... 60 4e-009
sp|Q95Y12|Y41D4_CAEEL Probable histone-lysine N-methyltransferas... 60 4e-009
sp|Q9EQQ0|SUV92_MOUSE Histone-lysine N-methyltransferase SUV39H2... 59 1e-008
sp|Q6DGD3|SV91A_DANRE Histone-lysine N-methyltransferase SUV39H1... 57 5e-008
sp|Q6YI93|SETB2_XENLA Histone-lysine N-methyltransferase SETDB2 ... 56 7e-008
sp|O64827|SUVR5_ARATH Histone-lysine N-methyltransferase SUVR5 O... 55 2e-007
sp|Q8C267|SETB2_MOUSE Histone-lysine N-methyltransferase SETDB2 ... 52 1e-006
sp|Q96T68|SETB2_HUMAN Histone-lysine N-methyltransferase SETDB2 ... 50 4e-006
>sp|O82175|SUVH5_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH5 OS=Arabidopsis thaliana GN=SUVH5 PE=2 SV=1
Length = 794
Score = 145 bits (364), Expect = 1e-034
Identities = 64/88 (72%), Positives = 74/88 (84%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 RPLPPKGCSCTAGCSDSEKCSCAVKNGGEIPFNFNGAIVEAKPLVYECGPSCKCPPSCHN 180
RP+PPK C CT GCS S+ C+C VKNGG+IP+ ++GAIVE KPLVYECGP CKCPPSC+
Sbjct: 580 RPIPPKSCGCTNGCSKSKNCACIVKNGGKIPY-YDGAIVEIKPLVYECGPHCKCPPSCNM 638
Query: 181 RVSQYGIKFHLEIFKTKSMGWGVRSLNS 264
RVSQ+GIK LEIFKT+S GWGVRSL S
Sbjct: 639 RVSQHGIKIKLEIFKTESRGWGVRSLES 666
>sp|Q8VZ17|SUVH6_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH6 OS=Arabidopsis thaliana GN=SUVH6 PE=2 SV=2
Length = 790
Score = 131 bits (329), Expect = 2e-030
Identities = 58/88 (65%), Positives = 69/88 (78%), Gaps = 2/88 (2%)
Frame = +1
Query: 7 LPPKGCSCTAGCSDSEK--CSCAVKNGGEIPFNFNGAIVEAKPLVYECGPSCKCPPSCHN 180
+PPK C CT C+++E C+C KNGGEIP+NF+GAIV AKP +YECGP CKCP SC+
Sbjct: 548 VPPKSCCCTTRCTEAEARVCACVEKNGGEIPYNFDGAIVGAKPTIYECGPLCKCPSSCYL 607
Query: 181 RVSQYGIKFHLEIFKTKSMGWGVRSLNS 264
RV+Q+GIK LEIFKTKS GWGVR L S
Sbjct: 608 RVTQHGIKLPLEIFKTKSRGWGVRCLKS 635
>sp|Q9T0G7|SUVH9_ARATH Probable histone-lysine N-methyltransferase, H3 lysine-9
specific SUVH9 OS=Arabidopsis thaliana GN=SUVH9 PE=2 SV=1
Length = 650
Score = 104 bits (259), Expect = 2e-022
Identities = 41/81 (50%), Positives = 57/81 (70%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 GCSCTAGCSDSEKCSCAVKNGGEIPFNFNGAIVEAKPLVYECGPSCKCPPSCHNRVSQYG 198
GC C GC C C KN GEI +++NG ++ KPL++ECG +C+CPPSC NRV+Q G
Sbjct: 433 GCDCVNGCGSG--CLCEAKNSGEIAYDYNGTLIRQKPLIHECGSACQCPPSCRNRVTQKG 490
Query: 199 IKFHLEIFKTKSMGWGVRSLN 261
++ LE+F++ GWGVRSL+
Sbjct: 491 LRNRLEVFRSLETGWGVRSLD 511
>sp|Q93YF5|SUVH1_TOBAC Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH1 OS=Nicotiana tabacum GN=SUVH1 PE=1 SV=1
Length = 704
Score = 98 bits (242), Expect = 2e-020
Identities = 40/85 (47%), Positives = 55/85 (64%), Gaps = 1/85 (1%)
Frame = +1
Query: 4 PLPPKGCSCTAGCSDSE-KCSCAVKNGGEIPFNFNGAIVEAKPLVYECGPSCKCPPSCHN 180
P P C C GC + C+C NGG +P++ G ++ K L++ECG +C CPP+C N
Sbjct: 483 PRPSPSCHCVGGCQPGDSNCACIQSNGGFLPYSSLGVLLSYKTLIHECGSACSCPPNCRN 542
Query: 181 RVSQYGIKFHLEIFKTKSMGWGVRS 255
R+SQ G K LE+FKTK+ GWG+RS
Sbjct: 543 RMSQGGPKARLEVFKTKNRGWGLRS 567
>sp|Q9C5P4|SUVH3_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH3 OS=Arabidopsis thaliana GN=SUVH3 PE=2 SV=2
Length = 669
Score = 98 bits (242), Expect = 2e-020
Identities = 42/86 (48%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = +1
Query: 10 PPKGCSCTAGCS-DSEKCSCAVKNGGEIPFNFNGAIVEAKPLVYECGPSCKCPPSCHNRV 186
P GCSC+ CS + CSC KN G++P+ +V +P++YECGP+C C SC NRV
Sbjct: 428 PVIGCSCSGSCSPGNHNCSCIRKNDGDLPYLNGVILVSRRPVIYECGPTCPCHASCKNRV 487
Query: 187 SQYGIKFHLEIFKTKSMGWGVRSLNS 264
Q G+K LE+FKT++ GWG+RS +S
Sbjct: 488 IQTGLKSRLEVFKTRNRGWGLRSWDS 513
>sp|Q8GZB6|SUVH4_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH4 OS=Arabidopsis thaliana GN=SUVH4 PE=1 SV=2
Length = 624
Score = 95 bits (234), Expect = 2e-019
Identities = 39/81 (48%), Positives = 57/81 (70%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 GCSCTAGCSDSEKCSCAVKNGGEIPF-NFN-GAIVEAKPLVYECGPSCKCPPSCHNRVSQ 192
GC+C C+DS+KC+CA NGG P+ + N G ++E++ +V+ECGP C C P C NR SQ
Sbjct: 382 GCNCRGSCTDSKKCACAKLNGGNFPYVDLNDGRLIESRDVVFECGPHCGCGPKCVNRTSQ 441
Query: 193 YGIKFHLEIFKTKSMGWGVRS 255
++F+LE+F++ GW VRS
Sbjct: 442 KRLRFNLEVFRSAKKGWAVRS 462
>sp|O22781|SUVH2_ARATH Histone-lysine N-methyltransferase, H3 lysine-9, H3
lysine-27, H4 lysine-20 and cytosine specific SUVH2 OS=Arabidopsis
thaliana GN=SUVH2 PE=1 SV=1
Length = 651
Score = 93 bits (230), Expect = 5e-019
Identities = 39/81 (48%), Positives = 56/81 (69%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 GCSCTAGCSDSEKCSCAVKNGGEIPFNFNGAIVEAKPLVYECGPSCKCPPSCHNRVSQYG 198
GC C C+D C CA KNGGE ++ NG +++ K +V+ECG C C PSC +RV+Q G
Sbjct: 435 GCECKLSCTDD--CLCARKNGGEFAYDDNGHLLKGKHVVFECGEFCTCGPSCKSRVTQKG 492
Query: 199 IKFHLEIFKTKSMGWGVRSLN 261
++ LE+F++K GWGVR+L+
Sbjct: 493 LRNRLEVFRSKETGWGVRTLD 513
>sp|Q9FF80|SUVH1_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH1 OS=Arabidopsis thaliana GN=SUVH1 PE=2 SV=1
Length = 670
Score = 93 bits (229), Expect = 7e-019
Identities = 40/83 (48%), Positives = 52/83 (62%), Gaps = 2/83 (2%)
Frame = +1
Query: 10 PPKGCSCTAGCSDSE-KCSCAVKNGGEIPFNFNGAIVEAKPLVYECGPSCKCPPSCHNRV 186
P GC C C C C KNGG+ P+ NG +V KP++YEC PSC C +C N+V
Sbjct: 430 PSFGCDCANLCKPGNLDCHCIRKNGGDFPYTGNGILVSRKPMIYECSPSCPC-STCKNKV 488
Query: 187 SQYGIKFHLEIFKTKSMGWGVRS 255
+Q G+K LE+FKT + GWG+RS
Sbjct: 489 TQMGVKVRLEVFKTANRGWGLRS 511
>sp|Q9C5P1|SUVH7_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific
SUVH7 OS=Arabidopsis thaliana GN=SUVH7 PE=2 SV=1
Length = 693
Score = 83 bits (204), Expect = 5e-016
Identities = 34/68 (50%), Positives = 48/68 (70%), Gaps = 1/68 (1%)
Frame = +1
Query: 52 EKCSCAVKNGGEIPFNFNGAIVEAKPLVYECGPSCKCPPSCHNRVSQYGIKFHLEIFKTK 231
+ C+C +NG +P++ N +V KPL+YECG SC CP C R+ Q G+K HLE+FKT+
Sbjct: 469 QNCTCVQRNGDLLPYH-NNILVCRKPLIYECGGSCPCPDHCPTRLVQTGLKLHLEVFKTR 527
Query: 232 SMGWGVRS 255
+ GWG+RS
Sbjct: 528 NCGWGLRS 535
>sp|Q9Z148|EHMT2_MOUSE Histone-lysine N-methyltransferase, H3 lysine-9 specific
3 OS=Mus musculus GN=Ehmt2 PE=1 SV=2
Length = 1263
Score = 65 bits (157), Expect = 1e-010
Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 9/87 (10%)
Frame = +1
Query: 22 CSCTAGCSDSE------KCSCAVKNGGEIPFNFNGAIVEAKPLVYECGPSCKCPPSCHNR 183
C+C CS S C G + FN PL++EC +C C SC NR
Sbjct: 1027 CTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKI---EPPLIFECNQACSCWRSCKNR 1083
Query: 184 VSQYGIKFHLEIFKTKSMGWGVRSLNS 264
V Q GIK L++++T MGWGVR+L +
Sbjct: 1084 VVQSGIKVRLQLYRTAKMGWGVRALQT 1110
>sp|Q9H9B1|EHMT1_HUMAN Histone-lysine N-methyltransferase, H3 lysine-9 specific
5 OS=Homo sapiens GN=EHMT1 PE=1 SV=3
Length = 1267
Score = 64 bits (155), Expect = 3e-010
Identities = 35/87 (40%), Positives = 48/87 (55%), Gaps = 13/87 (14%)
Frame = +1
Query: 22 CSCTAGCSDSEKCSCAV--------KNGGEIPFNFNGAIVEAKPLVYECGPSCKCPPSCH 177
C C CS S C C K+G +P FN A PL++EC +C C +C
Sbjct: 1031 CVCIDDCS-SSNCMCGQLSMRCWYDKDGRLLP-EFNMA---EPPLIFECNHACSCWRNCR 1085
Query: 178 NRVSQYGIKFHLEIFKTKSMGWGVRSL 258
NRV Q G++ L++++T+ MGWGVRSL
Sbjct: 1086 NRVVQNGLRARLQLYRTRDMGWGVRSL 1112
>sp|Q96KQ7|EHMT2_HUMAN Histone-lysine N-methyltransferase, H3 lysine-9 specific
3 OS=Homo sapiens GN=EHMT2 PE=1 SV=3
Length = 1210
Score = 64 bits (154), Expect = 3e-010
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 9/87 (10%)
Frame = +1
Query: 22 CSCTAGCSDSE------KCSCAVKNGGEIPFNFNGAIVEAKPLVYECGPSCKCPPSCHNR 183
C+C CS S C G + FN PL++EC +C C +C NR
Sbjct: 974 CTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKI---EPPLIFECNQACSCWRNCKNR 1030
Query: 184 VSQYGIKFHLEIFKTKSMGWGVRSLNS 264
V Q GIK L++++T MGWGVR+L +
Sbjct: 1031 VVQSGIKVRLQLYRTAKMGWGVRALQT 1057
>sp|O60016|CLR4_SCHPO Histone-lysine N-methyltransferase, H3 lysine-9 specific
OS=Schizosaccharomyces pombe GN=clr4 PE=1 SV=2
Length = 490
Score = 60 bits (145), Expect = 4e-009
Identities = 32/84 (38%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Frame = +1
Query: 22 CSCTAGC--SDSEKCSCA--VKNGGEIPFNFNGAI-VEAKPLVYECGPSCKCPPSCHNRV 186
CS GC ++ +C C + ++ G + + ++YEC C C C NRV
Sbjct: 262 CSSLGGCDLNNPSRCECLDDLDEPTHFAYDAQGRVRADTGAVIYECNSFCSCSMECPNRV 321
Query: 187 SQYGIKFHLEIFKTKSMGWGVRSL 258
Q G LEIFKTK GWGVRSL
Sbjct: 322 VQRGRTLPLEIFKTKEKGWGVRSL 345
>sp|Q95Y12|Y41D4_CAEEL Probable histone-lysine N-methyltransferase Y41D4B.12
OS=Caenorhabditis elegans GN=Y41D4B.12 PE=2 SV=1
Length = 244
Score = 60 bits (145), Expect = 4e-009
Identities = 34/85 (40%), Positives = 46/85 (54%), Gaps = 7/85 (8%)
Frame = +1
Query: 16 KGCSCTAGCSDSEKCSCAVKNGGEIPFNFNGAIVEAKPLVYECGPSCKC---PPSCHNRV 186
+GC+C A CS + CSC + + +G I ++ L+ EC C C P SC NRV
Sbjct: 25 EGCNCEAECSSAAGCSCLINKIDN--YTVDGKINKSSELLIECSDQCACILLPTSCRNRV 82
Query: 187 SQYGIKFHLEIFKTKSM--GWGVRS 255
Q G + LEIF T M G+GVR+
Sbjct: 83 VQCGPQKKLEIFSTCEMAKGFGVRA 107
>sp|Q9EQQ0|SUV92_MOUSE Histone-lysine N-methyltransferase SUV39H2 OS=Mus
musculus GN=Suv39h2 PE=1 SV=1
Length = 477
Score = 59 bits (140), Expect = 1e-008
Identities = 33/82 (40%), Positives = 46/82 (56%), Gaps = 5/82 (6%)
Frame = +1
Query: 19 GCSCTAGCSDSEKCSCAVKNGGEIPFNFNGAI-VEAKPLVYECGPSCKCPPSCHNRVSQY 195
GCSCT D KC C + G + +N I ++ +YEC C+C P C NR+ Q
Sbjct: 257 GCSCTDCFFD--KC-CPAEAGVVLAYNKKQQIKIQPGTPIYECNSRCRCGPECPNRIVQK 313
Query: 196 GIKFHLEIFKTKS-MGWGVRSL 258
G ++ L IFKT + GWGV++L
Sbjct: 314 GTQYSLCIFKTSNGCGWGVKTL 335
>sp|Q6DGD3|SV91A_DANRE Histone-lysine N-methyltransferase SUV39H1-A OS=Danio
rerio GN=suv39h1a PE=2 SV=2
Length = 411
Score = 57 bits (135), Expect = 5e-008
Identities = 29/56 (51%), Positives = 35/56 (62%), Gaps = 4/56 (7%)
Frame = +1
Query: 133 VYECGPSCKCPPSCHNRVSQYGIKFHLEIFKT-KSMGWGVRSL---NSHSFRKFYL 288
+YEC C+C P C NRV Q GI++ L IFKT GWGVR+L N +SF YL
Sbjct: 218 IYECNSKCRCGPDCANRVVQRGIQYDLCIFKTDNGRGWGVRTLQRINKNSFVMEYL 273
>sp|Q6YI93|SETB2_XENLA Histone-lysine N-methyltransferase SETDB2 OS=Xenopus
laevis GN=setdb2 PE=2 SV=1
Length = 699
Score = 56 bits (134), Expect = 7e-008
Identities = 24/44 (54%), Positives = 31/44 (70%), Gaps = 1/44 (2%)
Frame = +1
Query: 133 VYECGPSCKCPPS-CHNRVSQYGIKFHLEIFKTKSMGWGVRSLN 261
+YEC SCKC C NRV Q+G+K L++FKT + GWGVR L+
Sbjct: 362 LYECNVSCKCDRMLCQNRVVQHGLKLRLQVFKTNTKGWGVRCLD 405
>sp|O64827|SUVR5_ARATH Histone-lysine N-methyltransferase SUVR5 OS=Arabidopsis
thaliana GN=SUVR5 PE=1 SV=2
Length = 1114
Score = 55 bits (130), Expect = 2e-007
Identities = 24/48 (50%), Positives = 32/48 (66%)
Frame = +1
Query: 112 IVEAKPLVYECGPSCKCPPSCHNRVSQYGIKFHLEIFKTKSMGWGVRS 255
I+E VYEC C C +C NRV Q GI+ LE+F+T+S GWG+R+
Sbjct: 925 ILEEGYPVYECNKFCGCSRTCQNRVLQNGIRAKLEVFRTESKGWGLRA 972
>sp|Q8C267|SETB2_MOUSE Histone-lysine N-methyltransferase SETDB2 OS=Mus musculus
GN=Setdb2 PE=2 SV=2
Length = 713
Score = 52 bits (123), Expect = 1e-006
Identities = 21/44 (47%), Positives = 30/44 (68%), Gaps = 1/44 (2%)
Frame = +1
Query: 133 VYECGPSCKC-PPSCHNRVSQYGIKFHLEIFKTKSMGWGVRSLN 261
+YEC CKC C NRV Q+G++ L++FK++ GWGVR L+
Sbjct: 345 IYECNLLCKCNKQMCQNRVIQHGVRVRLQVFKSEKKGWGVRCLD 388
>sp|Q96T68|SETB2_HUMAN Histone-lysine N-methyltransferase SETDB2 OS=Homo sapiens
GN=SETDB2 PE=1 SV=2
Length = 719
Score = 50 bits (119), Expect = 4e-006
Identities = 22/44 (50%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Frame = +1
Query: 133 VYECGPSCKCPPS-CHNRVSQYGIKFHLEIFKTKSMGWGVRSLN 261
+YEC CKC C NRV Q+G + L++FKT+ GWGVR L+
Sbjct: 342 IYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLD 385
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,147,680,677
Number of Sequences: 462764
Number of Extensions: 17147680677
Number of Successful Extensions: 155595402
Number of sequences better than 0.0: 0
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