BLASTX 7.6.2
Query= RU13460 /QuerySize=698
(697 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q920N2|BPL1_MOUSE Biotin--protein ligase OS=Mus musculus GN=H... 86 1e-016
sp|P50747|BPL1_HUMAN Biotin--protein ligase OS=Homo sapiens GN=H... 85 3e-016
sp|O14353|BPL1_SCHPO Biotin--protein ligase OS=Schizosaccharomyc... 75 3e-013
sp|P46363|BIRA_HAEIN Bifunctional protein birA OS=Haemophilus in... 67 9e-011
sp|P06709|BIRA_ECOLI Bifunctional protein birA OS=Escherichia co... 60 1e-008
sp|P37416|BIRA_SALTY Bifunctional protein birA OS=Salmonella typ... 59 2e-008
sp|P42975|BIRA_BACSU Bifunctional protein birA OS=Bacillus subti... 56 2e-007
sp|P29906|BIRA_PARDE Biotin--[acetyl-CoA-carboxylase] synthetase... 51 7e-006
>sp|Q920N2|BPL1_MOUSE Biotin--protein ligase OS=Mus musculus GN=Hlcs PE=1 SV=1
Length = 722
Score = 86 bits (212), Expect = 1e-016
Identities = 45/135 (33%), Positives = 81/135 (60%), Gaps = 10/135 (7%)
Frame = +1
Query: 313 FGIDSFMNSLSTDRFGRLLLWSPRLPSTQDVVSQNFCELPN--GAVCVADVQYKGRGRSK 486
F ++++ +L T R G+++L++ +T ++ E+P G + +A Q +G+GR
Sbjct: 447 FSLETYRQNLQTTRLGKVILFAEVTSTTMSLLDGLMFEMPQEMGLIAIAVRQTQGKGRGP 506
Query: 487 NVWESPKGC----LLFSFTLQMEDGRIVPLIQYVVSLAITEAIKDVCDRNGLPYIDVRIK 654
N W SP GC LL L+ + G+ +P +Q+++SLA+ EA++ + G I++R+K
Sbjct: 507 NAWLSPVGCALSTLLVFIPLRSQLGQRIPFVQHLMSLAVVEAVRSI---PGYEDINLRVK 563
Query: 655 WPNDLYLNGL-KVGG 696
WPND+Y + L K+GG
Sbjct: 564 WPNDIYYSDLMKIGG 578
>sp|P50747|BPL1_HUMAN Biotin--protein ligase OS=Homo sapiens GN=HLCS PE=1 SV=1
Length = 726
Score = 85 bits (209), Expect = 3e-016
Identities = 44/135 (32%), Positives = 82/135 (60%), Gaps = 10/135 (7%)
Frame = +1
Query: 313 FGIDSFMNSLSTDRFGRLLLWSPRLPSTQDVVSQNFCELPN--GAVCVADVQYKGRGRSK 486
F ++ + +L T + G+++L++ P+T ++ + P G + +A Q +G+GR
Sbjct: 451 FNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGG 510
Query: 487 NVWESPKGC----LLFSFTLQMEDGRIVPLIQYVVSLAITEAIKDVCDRNGLPYIDVRIK 654
NVW SP GC LL S L+ + G+ +P +Q+++S+A+ EA++ + + I++R+K
Sbjct: 511 NVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQD---INLRVK 567
Query: 655 WPNDLYLNGL-KVGG 696
WPND+Y + L K+GG
Sbjct: 568 WPNDIYYSDLMKIGG 582
>sp|O14353|BPL1_SCHPO Biotin--protein ligase OS=Schizosaccharomyces pombe
GN=bpl1 PE=2 SV=1
Length = 631
Score = 75 bits (184), Expect = 3e-013
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 9/157 (5%)
Frame = +1
Query: 244 SDNGELSILLDSELKKPFKEDDAFGIDSFMNSLSTDRFGRLLLWSPRLPSTQDVVSQNFC 423
SDN + I E K K +F ++ + ++ RFG ++ +P + STQ ++ +N+
Sbjct: 315 SDNEIVKIWYGDEEKICKKAKPSFDLELYAKLINGCRFGLPIIVAPVIRSTQTLLDKNYR 374
Query: 424 ELPN---GAVCVADVQYKGRGRSKNVWESPKGCLLFSFTLQMEDGRI----VPLIQYVVS 582
L + G + + Q GRGR +N+W SP G L FSF + ++ + L QY+++
Sbjct: 375 FLDSTNTGFTVLGNYQTAGRGRGQNMWVSPYGTLAFSFIINVDAKNFSTTPIALFQYLMA 434
Query: 583 LAITEAIKDVCDRNGLPYIDVRIKWPNDLYLNGLKVG 693
LA+ I++ G I IKWPND+Y+ K G
Sbjct: 435 LAVVRGIREYAP--GYENIPAFIKWPNDVYVRVDKGG 469
>sp|P46363|BIRA_HAEIN Bifunctional protein birA OS=Haemophilus influenzae
GN=birA PE=3 SV=1
Length = 302
Score = 67 bits (162), Expect = 9e-011
Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 13/120 (10%)
Frame = +1
Query: 340 LSTDRFGRLLLWSPRLPSTQDVVSQNFCELPNGAVCVADVQYKGRGRSKNVWESP-KGCL 516
+ST F + + P + ST + + QN L G +CVA+ Q GRGR W SP G +
Sbjct: 63 ISTALFPYSIHYQPIISSTNEWILQNILSLKKGDLCVAEYQTAGRGRRGRQWLSPFAGQI 122
Query: 517 LFSFTLQMEDGRIVPLIQYVVSLAITEAIKDVCDRNGLPYIDVRIKWPNDLYLNGLKVGG 696
+FSF + + + + V+ LAI E ++V++KWPND+ + K+GG
Sbjct: 123 MFSFYWAFDPKKSIEGLSLVIGLAIAEV------------LNVQVKWPNDILFDERKLGG 170
>sp|P06709|BIRA_ECOLI Bifunctional protein birA OS=Escherichia coli (strain K12)
GN=birA PE=1 SV=1
Length = 321
Score = 60 bits (144), Expect = 1e-008
Identities = 39/107 (36%), Positives = 53/107 (49%), Gaps = 6/107 (5%)
Frame = +1
Query: 379 PRLPSTQDVVSQNFCELPNGAVCVADVQYKGRGRSKNVWESPKGCLLF-SFTLQMEDGRI 555
P + ST + EL +G C+A+ Q GRGR W SP G L+ S ++E G
Sbjct: 85 PVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQG-- 142
Query: 556 VPLIQYVVSLAITEAIKDVCDRNGLPYIDVRIKWPNDLYLNGLKVGG 696
P +SL I + +V + G VR+KWPNDLYL K+ G
Sbjct: 143 -PAAAIGLSLVIGIVMAEVLRKLGAD--KVRVKWPNDLYLQDRKLAG 186
>sp|P37416|BIRA_SALTY Bifunctional protein birA OS=Salmonella typhimurium
GN=birA PE=3 SV=2
Length = 320
Score = 59 bits (141), Expect = 2e-008
Identities = 40/107 (37%), Positives = 53/107 (49%), Gaps = 6/107 (5%)
Frame = +1
Query: 379 PRLPSTQDVVSQNFCELPNGAVCVADVQYKGRGRSKNVWESPKGCLLF-SFTLQMEDGRI 555
P + ST + EL +G CVA+ Q GRGR W SP G L+ S ++E G
Sbjct: 85 PVIDSTNQYLLDRIGELRSGDACVAEYQQAGRGRRGRKWFSPFGANLYLSMYWRLEQG-- 142
Query: 556 VPLIQYVVSLAITEAIKDVCDRNGLPYIDVRIKWPNDLYLNGLKVGG 696
P +SL I + +V + G VR+KWPNDLYL K+ G
Sbjct: 143 -PAAAIGLSLVIGIVMAEVLRKLGAD--KVRVKWPNDLYLLDRKLAG 186
>sp|P42975|BIRA_BACSU Bifunctional protein birA OS=Bacillus subtilis GN=birA
PE=1 SV=1
Length = 325
Score = 56 bits (133), Expect = 2e-007
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 19/144 (13%)
Frame = +1
Query: 283 LKKPFKEDDAFGIDSFMNSLSTDRFGRLLLWSPRLPSTQ----DVVSQNFCELPNGAVCV 450
+KKP K ++ L T+ G+ L++ L STQ ++ + N P G + V
Sbjct: 62 IKKPGKLSES----EIRFGLKTEVMGQHLIYHDVLSSTQKTAHELANNN---APEGTLVV 114
Query: 451 ADVQYKGRGRSKNVWESPKGCLLFSFTLQMEDGRI--VPLIQYVVSLAITEAIKDVCDRN 624
AD Q GRGR VW S +G ++ + D + P + + ++A+ + I++
Sbjct: 115 ADKQTAGRGRMSRVWHSQEGNGVWMSLILRPDIPLQKTPQLTLLAAVAVVQGIEEAAG-- 172
Query: 625 GLPYIDVRIKWPNDLYLNGLKVGG 696
I IKWPND+ +NG K G
Sbjct: 173 ----IQTDIKWPNDILINGKKTVG 192
>sp|P29906|BIRA_PARDE Biotin--[acetyl-CoA-carboxylase] synthetase OS=Paracoccus
denitrificans GN=birA PE=3 SV=1
Length = 240
Score = 51 bits (120), Expect = 7e-006
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Frame = +1
Query: 427 LPNGAVCVADVQYKGRGRSKNVWESPKGCLLFSFTLQMEDGRIVPL-IQYVVSLAITEAI 603
L A +A Q+ GRGR W P G + L+ + G + + +V +LA+ +A+
Sbjct: 19 LSGSAWVLAREQFAGRGRRGREWVMPAGNFAGTLVLRPQGGALAAAQLSFVAALALYDAL 78
Query: 604 KDVCDRNGLPYIDVRIKWPNDLYLNGLKVGG 696
C P + IKWPND+ LNG KV G
Sbjct: 79 GLACG----PAARLAIKWPNDVLLNGGKVAG 105
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,147,680,677
Number of Sequences: 462764
Number of Extensions: 17147680677
Number of Successful Extensions: 155595402
Number of sequences better than 0.0: 0
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