BLASTX 7.6.2 Query= RU20048 /QuerySize=884 (883 letters) Database: UniProt/Swiss-Prot; 462,764 sequences; 163,773,382 total letters Score E Sequences producing significant alignments: (bits) Value sp|P61219|RPAB2_MOUSE DNA-directed RNA polymerases I, II, and II... 132 3e-030 sp|O88828|RPAB2_RAT DNA-directed RNA polymerases I, II, and III ... 132 3e-030 sp|P61217|RPAB2_CRIGR DNA-directed RNA polymerases I, II, and II... 132 4e-030 sp|P61218|RPAB2_HUMAN DNA-directed RNA polymerases I, II, and II... 132 4e-030 sp|Q5R592|RPAB2_PONAB DNA-directed RNA polymerases I, II, and II... 132 4e-030 sp|Q32PE0|RPAB2_BOVIN DNA-directed RNA polymerases I, II, and II... 130 2e-029 sp|P20435|RPAB2_YEAST DNA-directed RNA polymerases I, II, and II... 130 2e-029 sp|Q17684|RPAB2_CAEEL Probable DNA-directed RNA polymerases I, I... 128 6e-029 sp|Q24320|RPAB2_DROME DNA-directed RNA polymerases I, II, and II... 124 7e-028 sp|P36595|RPAB2_SCHPO DNA-directed RNA polymerases I, II, and II... 124 1e-027 sp|A8WSV7|RPAB2_CAEBR Probable DNA-directed RNA polymerases I, I... 123 2e-027 sp|Q54FA8|RPAB2_DICDI DNA-directed RNA polymerases I, II, and II... 122 3e-027 sp|Q8PW42|RPOK_METMA DNA-directed RNA polymerase subunit K OS=Me... 62 3e-009 sp|Q9YDJ9|RPOK_AERPE DNA-directed RNA polymerase subunit K OS=Ae... 61 1e-008 sp|Q8TT40|RPOK_METAC DNA-directed RNA polymerase subunit K OS=Me... 61 1e-008 sp|Q5UQ32|RPO6_MIMIV DNA-directed RNA polymerase subunit 6 OS=Ac... 60 1e-008 sp|O26148|RPOK_METTH DNA-directed RNA polymerase subunit K OS=Me... 60 2e-008 sp|O29134|RPOK_ARCFU DNA-directed RNA polymerase subunit K OS=Ar... 59 3e-008 sp|A1RWX0|RPOK_THEPD DNA-directed RNA polymerase subunit K OS=Th... 59 3e-008 sp|Q8ZTF9|RPOK_PYRAE DNA-directed RNA polymerase subunit K OS=Py... 58 6e-008 sp|A2SSV2|RPOK_METLZ DNA-directed RNA polymerase subunit K OS=Me... 57 1e-007 sp|Q97ZJ9|RPOK_SULSO DNA-directed RNA polymerase subunit K OS=Su... 55 7e-007 sp|Q8U0E8|RPOK_PYRFU DNA-directed RNA polymerase subunit K OS=Py... 52 4e-006 >sp|P61219|RPAB2_MOUSE DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Mus musculus GN=Polr2f PE=2 SV=1 Length = 127 Score = 132 bits (331), Expect = 3e-030 Identities = 71/105 (67%), Positives = 80/105 (76%), Gaps = 6/105 (5%) Frame = -2 Query: 582 DDLAGDAIETDDKEEQVPV-ERP-----RKTSKFMTKYERARILGTRAVQISMNAPVMVE 421 DDL E + E +P ERP R T+ +MTKYERAR+LGTRA+QI+M APVMVE Sbjct: 23 DDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVE 82 Query: 420 LEGETDPLEIAMKELRERKIPFTIRRYLPDGSYEDWGVDELIVED 286 LEGETDPL IAMKEL+ RKIP IRRYLPDGSYEDWGVDELI+ D Sbjct: 83 LEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIISD 127 >sp|O88828|RPAB2_RAT DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Rattus norvegicus GN=Polr2f PE=1 SV=1 Length = 127 Score = 132 bits (331), Expect = 3e-030 Identities = 71/105 (67%), Positives = 80/105 (76%), Gaps = 6/105 (5%) Frame = -2 Query: 582 DDLAGDAIETDDKEEQVPV-ERP-----RKTSKFMTKYERARILGTRAVQISMNAPVMVE 421 DDL E + E +P ERP R T+ +MTKYERAR+LGTRA+QI+M APVMVE Sbjct: 23 DDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVE 82 Query: 420 LEGETDPLEIAMKELRERKIPFTIRRYLPDGSYEDWGVDELIVED 286 LEGETDPL IAMKEL+ RKIP IRRYLPDGSYEDWGVDELI+ D Sbjct: 83 LEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIISD 127 >sp|P61217|RPAB2_CRIGR DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Cricetulus griseus GN=POLR2F PE=2 SV=1 Length = 127 Score = 132 bits (330), Expect = 4e-030 Identities = 71/105 (67%), Positives = 80/105 (76%), Gaps = 6/105 (5%) Frame = -2 Query: 582 DDLAGDAIETDDKEEQVPV-ERP-----RKTSKFMTKYERARILGTRAVQISMNAPVMVE 421 DDL E + E +P ERP R T+ +MTKYERAR+LGTRA+QI+M APVMVE Sbjct: 23 DDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVE 82 Query: 420 LEGETDPLEIAMKELRERKIPFTIRRYLPDGSYEDWGVDELIVED 286 LEGETDPL IAMKEL+ RKIP IRRYLPDGSYEDWGVDELI+ D Sbjct: 83 LEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIITD 127 >sp|P61218|RPAB2_HUMAN DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Homo sapiens GN=POLR2F PE=1 SV=1 Length = 127 Score = 132 bits (330), Expect = 4e-030 Identities = 71/105 (67%), Positives = 80/105 (76%), Gaps = 6/105 (5%) Frame = -2 Query: 582 DDLAGDAIETDDKEEQVPV-ERP-----RKTSKFMTKYERARILGTRAVQISMNAPVMVE 421 DDL E + E +P ERP R T+ +MTKYERAR+LGTRA+QI+M APVMVE Sbjct: 23 DDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVE 82 Query: 420 LEGETDPLEIAMKELRERKIPFTIRRYLPDGSYEDWGVDELIVED 286 LEGETDPL IAMKEL+ RKIP IRRYLPDGSYEDWGVDELI+ D Sbjct: 83 LEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIITD 127 >sp|Q5R592|RPAB2_PONAB DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Pongo abelii GN=POLR2F PE=2 SV=1 Length = 127 Score = 132 bits (330), Expect = 4e-030 Identities = 71/105 (67%), Positives = 80/105 (76%), Gaps = 6/105 (5%) Frame = -2 Query: 582 DDLAGDAIETDDKEEQVPV-ERP-----RKTSKFMTKYERARILGTRAVQISMNAPVMVE 421 DDL E + E +P ERP R T+ +MTKYERAR+LGTRA+QI+M APVMVE Sbjct: 23 DDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVE 82 Query: 420 LEGETDPLEIAMKELRERKIPFTIRRYLPDGSYEDWGVDELIVED 286 LEGETDPL IAMKEL+ RKIP IRRYLPDGSYEDWGVDELI+ D Sbjct: 83 LEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIITD 127 >sp|Q32PE0|RPAB2_BOVIN DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Bos taurus GN=POLR2F PE=2 SV=1 Length = 127 Score = 130 bits (325), Expect = 2e-029 Identities = 71/105 (67%), Positives = 79/105 (75%), Gaps = 6/105 (5%) Frame = -2 Query: 582 DDLAGDAIETDDKEEQVPV-ERP-----RKTSKFMTKYERARILGTRAVQISMNAPVMVE 421 DDL E E +P ERP R T+ +MTKYERAR+LGTRA+QI+M APVMVE Sbjct: 23 DDLENAEEEGQVNVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVE 82 Query: 420 LEGETDPLEIAMKELRERKIPFTIRRYLPDGSYEDWGVDELIVED 286 LEGETDPL IAMKEL+ RKIP IRRYLPDGSYEDWGVDELI+ D Sbjct: 83 LEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIITD 127 >sp|P20435|RPAB2_YEAST DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Saccharomyces cerevisiae GN=RPO26 PE=1 SV=1 Length = 155 Score = 130 bits (325), Expect = 2e-029 Identities = 63/86 (73%), Positives = 75/86 (87%), Gaps = 1/86 (1%) Frame = -2 Query: 546 KEEQVPVERPRKTSKFMTKYERARILGTRAVQISMNAPVMVELEGETDPLEIAMKELRER 367 KE+ +P ++ R T+ +MTKYERARILGTRA+QISMNAPV V+LEGETDPL IAMKEL E+ Sbjct: 70 KEKAIPKDQ-RATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEK 128 Query: 366 KIPFTIRRYLPDGSYEDWGVDELIVE 289 KIP IRRYLPDGS+EDW V+ELIV+ Sbjct: 129 KIPLVIRRYLPDGSFEDWSVEELIVD 154 >sp|Q17684|RPAB2_CAEEL Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Caenorhabditis elegans GN=rpb-6 PE=2 SV=1 Length = 137 Score = 128 bits (320), Expect = 6e-029 Identities = 63/102 (61%), Positives = 77/102 (75%), Gaps = 1/102 (0%) Frame = -2 Query: 591 DNNDDLAGDAIETDDKEEQVPVERPRKTSKFMTKYERARILGTRAVQISMNAPVMVELEG 412 D +DD + E D+ + VP T+ FMTKYERAR+LGTRA+QI+M APVMVELEG Sbjct: 36 DEDDDNVDENFELFDQGKAVPTSE-HVTTPFMTKYERARVLGTRALQIAMGAPVMVELEG 94 Query: 411 ETDPLEIAMKELRERKIPFTIRRYLPDGSYEDWGVDELIVED 286 ETDPLEIA KEL++R+IP +RRYLPDGSYEDW D+L + D Sbjct: 95 ETDPLEIARKELKQRRIPIIVRRYLPDGSYEDWPTDQLQLAD 136 >sp|Q24320|RPAB2_DROME DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Drosophila melanogaster GN=RpII18 PE=1 SV=1 Length = 131 Score = 124 bits (311), Expect = 7e-028 Identities = 57/78 (73%), Positives = 71/78 (91%) Frame = -2 Query: 516 RKTSKFMTKYERARILGTRAVQISMNAPVMVELEGETDPLEIAMKELRERKIPFTIRRYL 337 R T+K+MTKYERAR+LGTRA+QI+M AP+MVEL+GETDPL+IAMKEL+++KIP IRRYL Sbjct: 54 RITTKYMTKYERARVLGTRALQIAMCAPIMVELDGETDPLQIAMKELKQKKIPIIIRRYL 113 Query: 336 PDGSYEDWGVDELIVEDS 283 PD SYEDW +DELI+ D+ Sbjct: 114 PDHSYEDWSIDELIMVDN 131 >sp|P36595|RPAB2_SCHPO DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Schizosaccharomyces pombe GN=rpb6 PE=2 SV=1 Length = 142 Score = 124 bits (309), Expect = 1e-027 Identities = 58/74 (78%), Positives = 67/74 (90%) Frame = -2 Query: 516 RKTSKFMTKYERARILGTRAVQISMNAPVMVELEGETDPLEIAMKELRERKIPFTIRRYL 337 R T+ +MTKYERARILGTRA+QISMNAPV+V+LEGETDPL+IAMKEL ++KIP +RRYL Sbjct: 69 RTTTPYMTKYERARILGTRALQISMNAPVLVDLEGETDPLQIAMKELAQKKIPLLVRRYL 128 Query: 336 PDGSYEDWGVDELI 295 PDGSYEDW V ELI Sbjct: 129 PDGSYEDWSVAELI 142 >sp|A8WSV7|RPAB2_CAEBR Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Caenorhabditis briggsae GN=rpb-6 PE=3 SV=1 Length = 138 Score = 123 bits (308), Expect = 2e-027 Identities = 60/102 (58%), Positives = 78/102 (76%), Gaps = 1/102 (0%) Frame = -2 Query: 591 DNNDDLAGDAIETDDKEEQVPVERPRKTSKFMTKYERARILGTRAVQISMNAPVMVELEG 412 +++D+ + E D+ + VP T+ FMTKYERAR+LGTRA+QI+M APVMVELEG Sbjct: 37 EDDDNNVDENFELFDQGKAVPTSE-HVTTPFMTKYERARVLGTRALQIAMGAPVMVELEG 95 Query: 411 ETDPLEIAMKELRERKIPFTIRRYLPDGSYEDWGVDELIVED 286 ETDPLEIA KEL++R++P IRRYLPDGSYEDW ++L + D Sbjct: 96 ETDPLEIARKELKQRRVPIIIRRYLPDGSYEDWPTEQLQLAD 137 >sp|Q54FA8|RPAB2_DICDI DNA-directed RNA polymerases I, II, and III subunit rpabc2 OS=Dictyostelium discoideum GN=polr2f PE=3 SV=1 Length = 133 Score = 122 bits (306), Expect = 3e-027 Identities = 56/75 (74%), Positives = 68/75 (90%) Frame = -2 Query: 516 RKTSKFMTKYERARILGTRAVQISMNAPVMVELEGETDPLEIAMKELRERKIPFTIRRYL 337 RKT+++MTKYERAR+LG+RA+QISMNAP+MVELEGETDPL+IA KELR +KIP IRR+L Sbjct: 59 RKTTRYMTKYERARLLGSRALQISMNAPIMVELEGETDPLQIAWKELRAKKIPLIIRRFL 118 Query: 336 PDGSYEDWGVDELIV 292 P+G YEDW VDEL + Sbjct: 119 PNGMYEDWSVDELSI 133 >sp|Q8PW42|RPOK_METMA DNA-directed RNA polymerase subunit K OS=Methanosarcina mazei GN=rpoK PE=3 SV=1 Length = 83 Score = 62 bits (150), Expect = 3e-009 Identities = 28/51 (54%), Positives = 41/51 (80%) Frame = -2 Query: 495 TKYERARILGTRAVQISMNAPVMVELEGETDPLEIAMKELRERKIPFTIRR 343 T++ERARI+G RA+QI+M APV+VE +G DPL +A++EL+ IP T++R Sbjct: 30 TRFERARIVGARALQIAMGAPVLVEDDGRLDPLGVAIEELKAGVIPITVKR 80 >sp|Q9YDJ9|RPOK_AERPE DNA-directed RNA polymerase subunit K OS=Aeropyrum pernix GN=rpoK PE=3 SV=2 Length = 89 Score = 61 bits (146), Expect = 1e-008 Identities = 31/71 (43%), Positives = 46/71 (64%), Gaps = 2/71 (2%) Frame = -2 Query: 501 FMTKYERARILGTRAVQISMNAPVMVELE--GETDPLEIAMKELRERKIPFTIRRYLPDG 328 ++TKYERARI+G RA Q+S+ AP +V+ E G +PL+IA E+ +P +I RYLP G Sbjct: 7 YLTKYERARIIGVRAFQLSIGAPPLVDPERAGSRNPLDIARYEVDNGILPVSIYRYLPGG 66 Query: 327 SYEDWGVDELI 295 + + L+ Sbjct: 67 GGQSLSLSRLV 77 >sp|Q8TT40|RPOK_METAC DNA-directed RNA polymerase subunit K OS=Methanosarcina acetivorans GN=rpoK PE=3 SV=1 Length = 60 Score = 61 bits (146), Expect = 1e-008 Identities = 27/51 (52%), Positives = 40/51 (78%) Frame = -2 Query: 495 TKYERARILGTRAVQISMNAPVMVELEGETDPLEIAMKELRERKIPFTIRR 343 T++ERARI+G RA+QI+M APV+V+ +G DPL +A+ EL+ IP T++R Sbjct: 7 TRFERARIVGARALQIAMGAPVLVDDDGRLDPLGVAIAELKAEIIPITVKR 57 >sp|Q5UQ32|RPO6_MIMIV DNA-directed RNA polymerase subunit 6 OS=Acanthamoeba polyphaga mimivirus GN=MIMI_R209 PE=3 SV=1 Length = 396 Score = 60 bits (145), Expect = 1e-008 Identities = 30/76 (39%), Positives = 43/76 (56%) Frame = -2 Query: 525 ERPRKTSKFMTKYERARILGTRAVQISMNAPVMVELEGETDPLEIAMKELRERKIPFTIR 346 + R+T +T YE RILGTRA Q + A +++ P ++A EL + F +R Sbjct: 184 DNERETDPILTYYEIVRILGTRAQQFNYGAKPLIKGVEGMHPAKMAFVELTAKMTSFIVR 243 Query: 345 RYLPDGSYEDWGVDEL 298 R+LP YEDW +DEL Sbjct: 244 RHLPGKKYEDWRIDEL 259 >sp|O26148|RPOK_METTH DNA-directed RNA polymerase subunit K OS=Methanobacterium thermoautotrophicum GN=rpoK PE=3 SV=1 Length = 61 Score = 60 bits (144), Expect = 2e-008 Identities = 27/55 (49%), Positives = 42/55 (76%) Frame = -2 Query: 507 SKFMTKYERARILGTRAVQISMNAPVMVELEGETDPLEIAMKELRERKIPFTIRR 343 SK +T++ERAR++G RA+QISM A +VE++ DP++IA KEL ++ +P +RR Sbjct: 5 SKKLTRFERARLIGARALQISMGARPLVEIKESLDPVDIARKELEKKVMPLDVRR 59 >sp|O29134|RPOK_ARCFU DNA-directed RNA polymerase subunit K OS=Archaeoglobus fulgidus GN=rpoK PE=3 SV=1 Length = 75 Score = 59 bits (142), Expect = 3e-008 Identities = 27/51 (52%), Positives = 41/51 (80%), Gaps = 1/51 (1%) Frame = -2 Query: 495 TKYERARILGTRAVQISMNAPVMVELEGETDPLEIAMKELRERKIPFTIRR 343 T++E+ARI+G RA+QI+M APV++E + +T+PLEIA++E IP T+RR Sbjct: 12 TRFEKARIIGARALQIAMGAPVLIETD-KTEPLEIALEEFNRGVIPITVRR 61 >sp|A1RWX0|RPOK_THEPD DNA-directed RNA polymerase subunit K OS=Thermofilum pendens (strain Hrk 5) GN=rpoK PE=3 SV=1 Length = 81 Score = 59 bits (142), Expect = 3e-008 Identities = 27/63 (42%), Positives = 46/63 (73%), Gaps = 1/63 (1%) Frame = -2 Query: 501 FMTKYERARILGTRAVQISMNAPVMVELEGE-TDPLEIAMKELRERKIPFTIRRYLPDGS 325 ++T++ERARI+G RA+QIS+ APV++++ E +DP+ IA KEL +P + R+ P+G Sbjct: 7 WLTRFERARIIGIRALQISLGAPVLIQVSEELSDPITIAEKELELGLLPIIVVRWTPEGK 66 Query: 324 YED 316 ++ Sbjct: 67 IQE 69 >sp|Q8ZTF9|RPOK_PYRAE DNA-directed RNA polymerase subunit K OS=Pyrobaculum aerophilum GN=rpoK PE=3 SV=1 Length = 106 Score = 58 bits (139), Expect = 6e-008 Identities = 29/59 (49%), Positives = 42/59 (71%), Gaps = 2/59 (3%) Frame = -2 Query: 498 MTKYERARILGTRAVQISMNAPVMVELE--GETDPLEIAMKELRERKIPFTIRRYLPDG 328 +TKYE ARI+G RA+Q++M A +V+++ G DP+ IAM+ELR + F I R +PDG Sbjct: 31 LTKYETARIIGARALQLAMGAQPLVDIQEVGSVDPVLIAMEELRRGLLDFIIVREMPDG 89 >sp|A2SSV2|RPOK_METLZ DNA-directed RNA polymerase subunit K OS=Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) GN=rpoK PE=3 SV=1 Length = 62 Score = 57 bits (136), Expect = 1e-007 Identities = 27/51 (52%), Positives = 40/51 (78%), Gaps = 1/51 (1%) Frame = -2 Query: 495 TKYERARILGTRAVQISMNAPVMVELEGETDPLEIAMKELRERKIPFTIRR 343 T+YERARI+G RA+QISM APV+V+ + DPL+IA++E ++P T++R Sbjct: 4 TRYERARIVGARALQISMGAPVLVKTV-KIDPLDIALEEFDADRVPITVKR 53 >sp|Q97ZJ9|RPOK_SULSO DNA-directed RNA polymerase subunit K OS=Sulfolobus solfataricus GN=rpoK PE=1 SV=1 Length = 95 Score = 55 bits (130), Expect = 7e-007 Identities = 25/59 (42%), Positives = 40/59 (67%), Gaps = 2/59 (3%) Frame = -2 Query: 498 MTKYERARILGTRAVQISMNAPVMVELE--GETDPLEIAMKELRERKIPFTIRRYLPDG 328 +T+YE AR++ RA+Q++M AP ++++ TD + IA +E R +P TIRR LP+G Sbjct: 27 LTRYEIARVISARALQLAMGAPALIDINNLSSTDVISIAEEEFRRGVLPITIRRRLPNG 85 >sp|Q8U0E8|RPOK_PYRFU DNA-directed RNA polymerase subunit K OS=Pyrococcus furiosus GN=rpoK PE=3 SV=1 Length = 57 Score = 52 bits (123), Expect = 4e-006 Identities = 24/51 (47%), Positives = 36/51 (70%) Frame = -2 Query: 495 TKYERARILGTRAVQISMNAPVMVELEGETDPLEIAMKELRERKIPFTIRR 343 T++E+ARI+G RA+QISM APV++++ PLE A+ E + IP T+ R Sbjct: 5 TRFEKARIIGARALQISMGAPVLIDVPPGITPLEAAILEFEKGVIPITVIR 55 Database: UniProt/Swiss-Prot Posted date: Thu Apr 23 14:22:33 2009 Number of letters in database: 163,773,382 Number of sequences in database: 462,764 Lambda K H 0.267 0.041 0.140 Gapped Lambda K H 0.267 0.041 0.140 Matrix: blosum62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,133,449,078 Number of Sequences: 462764 Number of Extensions: 22133449078 Number of Successful Extensions: 193841713 Number of sequences better than 0.0: 0 |