BLASTX 7.6.2
Query= RU20935 /QuerySize=653
(652 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q42806|KPYC_SOYBN Pyruvate kinase, cytosolic isozyme OS=Glyci... 99 2e-020
sp|P22200|KPYC_SOLTU Pyruvate kinase, cytosolic isozyme OS=Solan... 99 2e-020
sp|Q42954|KPYC_TOBAC Pyruvate kinase, cytosolic isozyme OS=Nicot... 97 9e-020
sp|O65595|KPYC_ARATH Probable pyruvate kinase, cytosolic isozyme... 96 2e-019
sp|Q8Z6K2|KPYK1_SALTI Pyruvate kinase I OS=Salmonella typhi GN=p... 86 2e-016
sp|P77983|KPYK1_SALTY Pyruvate kinase I OS=Salmonella typhimuriu... 86 2e-016
sp|P0AD62|KPYK1_ECO57 Pyruvate kinase I OS=Escherichia coli O157... 85 4e-016
sp|P0AD61|KPYK1_ECOLI Pyruvate kinase I OS=Escherichia coli (str... 85 4e-016
sp|Q2FG40|KPYK_STAA3 Pyruvate kinase OS=Staphylococcus aureus (s... 83 1e-015
sp|Q2FXM9|KPYK_STAA8 Pyruvate kinase OS=Staphylococcus aureus (s... 83 1e-015
sp|Q2YTE3|KPYK_STAAB Pyruvate kinase OS=Staphylococcus aureus (s... 83 1e-015
sp|Q5HF76|KPYK_STAAC Pyruvate kinase OS=Staphylococcus aureus (s... 83 1e-015
sp|Q99TG5|KPYK_STAAM Pyruvate kinase OS=Staphylococcus aureus (s... 83 1e-015
sp|Q7A559|KPYK_STAAN Pyruvate kinase OS=Staphylococcus aureus (s... 83 1e-015
sp|Q6GG09|KPYK_STAAR Pyruvate kinase OS=Staphylococcus aureus (s... 83 1e-015
sp|Q6G8M9|KPYK_STAAS Pyruvate kinase OS=Staphylococcus aureus (s... 83 1e-015
sp|Q7A0N4|KPYK_STAAW Pyruvate kinase OS=Staphylococcus aureus (s... 83 1e-015
sp|Q56301|KPYK_THELI Pyruvate kinase (Fragment) OS=Thermococcus ... 82 3e-015
sp|Q27788|KPYK_TRYBO Pyruvate kinase OS=Trypanoplasma borreli GN... 78 4e-014
sp|P30616|KPYK2_TRYBB Pyruvate kinase 2 OS=Trypanosoma brucei br... 76 1e-013
sp|Q54RF5|KPYK_DICDI Pyruvate kinase OS=Dictyostelium discoideum... 76 1e-013
sp|Q27686|KPYK_LEIME Pyruvate kinase OS=Leishmania mexicana GN=P... 75 2e-013
sp|Q5HNK7|KPYK_STAEQ Pyruvate kinase OS=Staphylococcus epidermid... 75 2e-013
sp|Q8CS69|KPYK_STAES Pyruvate kinase OS=Staphylococcus epidermid... 75 2e-013
sp|P30615|KPYK1_TRYBB Pyruvate kinase 1 OS=Trypanosoma brucei br... 75 3e-013
sp|Q49YC7|KPYK_STAS1 Pyruvate kinase OS=Staphylococcus saprophyt... 74 6e-013
sp|Q02499|KPYK_BACST Pyruvate kinase OS=Bacillus stearothermophi... 74 8e-013
sp|P51181|KPYK_BACLI Pyruvate kinase OS=Bacillus licheniformis G... 73 1e-012
sp|P80885|KPYK_BACSU Pyruvate kinase OS=Bacillus subtilis GN=pyk... 72 2e-012
sp|P51182|KPYK_BACPY Pyruvate kinase OS=Bacillus psychrophilus G... 72 3e-012
>sp|Q42806|KPYC_SOYBN Pyruvate kinase, cytosolic isozyme OS=Glycine max PE=2
SV=1
Length = 511
Score = 99 bits (245), Expect = 2e-020
Identities = 56/120 (46%), Positives = 77/120 (64%), Gaps = 1/120 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV TLGP SRS E+ L AGM+VARF+FS G +YHQETL+NLK A+ +T LCAV
Sbjct: 23 TKIVCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHDYHQETLNNLKTAMHNTGILCAV 82
Query: 251 MLDTVGPELQV-VNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTV 75
MLDT GPE++ + K I+LK V +T D + E++ +++ L + G+T+
Sbjct: 83 MLDTKGPEIRTGFLKDGKPIQLKEGQEVTITTDYDIKGDPEMISMSYKKLPVHLKPGNTI 142
>sp|P22200|KPYC_SOLTU Pyruvate kinase, cytosolic isozyme OS=Solanum tuberosum
PE=2 SV=1
Length = 510
Score = 99 bits (244), Expect = 2e-020
Identities = 54/120 (45%), Positives = 79/120 (65%), Gaps = 1/120 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV TLGP SR+ ++ L AGM+VARF+FS G EYHQETLDNLK A+++T+ LCAV
Sbjct: 22 TKIVCTLGPSSRTVPMLEKLLRAGMNVARFNFSHGTHEYHQETLDNLKIAMQNTQILCAV 81
Query: 251 MLDTVGPELQV-VNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTV 75
MLDT GPE++ K I+LK + ++ D + + E++ +++ L + G+T+
Sbjct: 82 MLDTKGPEIRTGFLTDGKPIQLKEGQEITVSTDYTIKGNEEMISMSYKKLVMDLKPGNTI 141
>sp|Q42954|KPYC_TOBAC Pyruvate kinase, cytosolic isozyme OS=Nicotiana tabacum
PE=2 SV=1
Length = 508
Score = 97 bits (239), Expect = 9e-020
Identities = 55/130 (42%), Positives = 81/130 (62%), Gaps = 3/130 (2%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV TLGP SRS +I L AGM+VARF+FS G+ +YHQET+DNL+ A++ST LCAV
Sbjct: 20 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHDYHQETIDNLRQAMESTGILCAV 79
Query: 251 MLDTVGPELQV-VNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTV 75
MLDT GPE++ + K ++LK + ++ D + ++ +++ L++ V +
Sbjct: 80 MLDTKGPEIRTGFLKDAKPVQLKQGQEITISTDYSIKGDESMICMSYKKLAEDVKPQSVI 139
Query: 74 FI--GQYLFT 51
GQ FT
Sbjct: 140 LCADGQITFT 149
>sp|O65595|KPYC_ARATH Probable pyruvate kinase, cytosolic isozyme OS=Arabidopsis
thaliana GN=At4g26390 PE=2 SV=1
Length = 497
Score = 96 bits (237), Expect = 2e-019
Identities = 54/117 (46%), Positives = 76/117 (64%), Gaps = 1/117 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV TLGP SRS ++ L AGMSVARF+FS G+ EYHQETLDNL+ A+ +T LCAV
Sbjct: 9 TKIVCTLGPASRSVPMVEKLLMAGMSVARFNFSHGSYEYHQETLDNLRQAMLNTGMLCAV 68
Query: 251 MLDTVGPELQV-VNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKG 84
MLDT GPE++ + K I+LK + ++ D + + + +++ L++ V G
Sbjct: 69 MLDTKGPEIRTGFLKDGKPIQLKQGQEITISTDYDLKGDEKTICMSYKKLAQDVNPG 125
>sp|Q8Z6K2|KPYK1_SALTI Pyruvate kinase I OS=Salmonella typhi GN=pykF PE=3 SV=1
Length = 470
Score = 86 bits (211), Expect = 2e-016
Identities = 46/134 (34%), Positives = 78/134 (58%), Gaps = 2/134 (1%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GPK+ S E++S L+AGM+V R +FS G+ H + + NL+ + T K A+
Sbjct: 4 TKIVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKKAAI 63
Query: 251 MLDTVGPELQVVN-RGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTV 75
+LDT GPE++ + G + LK T D+ ++E++ + ++G + ++ G+TV
Sbjct: 64 LLDTKGPEIRTIKLEGGNDVSLKAGQTFTFTTDKSVVGNNEIVAVTYEGFTSDLSVGNTV 123
Query: 74 FIGQYLFTGSETTS 33
+ L G E T+
Sbjct: 124 LVDDGLI-GMEVTA 136
>sp|P77983|KPYK1_SALTY Pyruvate kinase I OS=Salmonella typhimurium GN=pykF PE=3
SV=2
Length = 470
Score = 86 bits (211), Expect = 2e-016
Identities = 46/134 (34%), Positives = 78/134 (58%), Gaps = 2/134 (1%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GPK+ S E++S L+AGM+V R +FS G+ H + + NL+ + T K A+
Sbjct: 4 TKIVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKKAAI 63
Query: 251 MLDTVGPELQVVN-RGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTV 75
+LDT GPE++ + G + LK T D+ ++E++ + ++G + ++ G+TV
Sbjct: 64 LLDTKGPEIRTIKLEGGNDVSLKAGQTFTFTTDKSVVGNNEIVAVTYEGFTSDLSVGNTV 123
Query: 74 FIGQYLFTGSETTS 33
+ L G E T+
Sbjct: 124 LVDDGLI-GMEVTA 136
>sp|P0AD62|KPYK1_ECO57 Pyruvate kinase I OS=Escherichia coli O157:H7 GN=pykF
PE=3 SV=1
Length = 470
Score = 85 bits (208), Expect = 4e-016
Identities = 46/134 (34%), Positives = 78/134 (58%), Gaps = 2/134 (1%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GPK+ S E+++ L+AGM+V R +FS G+ H + + NL+ + T K A+
Sbjct: 4 TKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAI 63
Query: 251 MLDTVGPELQVVN-RGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTV 75
+LDT GPE++ + G + LK T D+ +SE++ + ++G + ++ G+TV
Sbjct: 64 LLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTV 123
Query: 74 FIGQYLFTGSETTS 33
+ L G E T+
Sbjct: 124 LVDDGLI-GMEVTA 136
>sp|P0AD61|KPYK1_ECOLI Pyruvate kinase I OS=Escherichia coli (strain K12)
GN=pykF PE=1 SV=1
Length = 470
Score = 85 bits (208), Expect = 4e-016
Identities = 46/134 (34%), Positives = 78/134 (58%), Gaps = 2/134 (1%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GPK+ S E+++ L+AGM+V R +FS G+ H + + NL+ + T K A+
Sbjct: 4 TKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAI 63
Query: 251 MLDTVGPELQVVN-RGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTV 75
+LDT GPE++ + G + LK T D+ +SE++ + ++G + ++ G+TV
Sbjct: 64 LLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTV 123
Query: 74 FIGQYLFTGSETTS 33
+ L G E T+
Sbjct: 124 LVDDGLI-GMEVTA 136
>sp|Q2FG40|KPYK_STAA3 Pyruvate kinase OS=Staphylococcus aureus (strain USA300)
GN=pyk PE=3 SV=1
Length = 585
Score = 83 bits (204), Expect = 1e-015
Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E+I +NAGM+VAR +FS G+ E H+ +D ++ K K+ A+
Sbjct: 4 TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ N + IIEL+ VI++ ++ E + E + ++ L V G +
Sbjct: 64 LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|Q2FXM9|KPYK_STAA8 Pyruvate kinase OS=Staphylococcus aureus (strain NCTC
8325) GN=pyk PE=3 SV=1
Length = 585
Score = 83 bits (204), Expect = 1e-015
Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E+I +NAGM+VAR +FS G+ E H+ +D ++ K K+ A+
Sbjct: 4 TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ N + IIEL+ VI++ ++ E + E + ++ L V G +
Sbjct: 64 LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|Q2YTE3|KPYK_STAAB Pyruvate kinase OS=Staphylococcus aureus (strain bovine
RF122 / ET3-1) GN=pyk PE=3 SV=1
Length = 585
Score = 83 bits (204), Expect = 1e-015
Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E+I +NAGM+VAR +FS G+ E H+ +D ++ K K+ A+
Sbjct: 4 TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ N + IIEL+ VI++ ++ E + E + ++ L V G +
Sbjct: 64 LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|Q5HF76|KPYK_STAAC Pyruvate kinase OS=Staphylococcus aureus (strain COL)
GN=pyk PE=3 SV=1
Length = 585
Score = 83 bits (204), Expect = 1e-015
Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E+I +NAGM+VAR +FS G+ E H+ +D ++ K K+ A+
Sbjct: 4 TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ N + IIEL+ VI++ ++ E + E + ++ L V G +
Sbjct: 64 LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|Q99TG5|KPYK_STAAM Pyruvate kinase OS=Staphylococcus aureus (strain Mu50 /
ATCC 700699) GN=pyk PE=1 SV=1
Length = 585
Score = 83 bits (204), Expect = 1e-015
Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E+I +NAGM+VAR +FS G+ E H+ +D ++ K K+ A+
Sbjct: 4 TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ N + IIEL+ VI++ ++ E + E + ++ L V G +
Sbjct: 64 LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|Q7A559|KPYK_STAAN Pyruvate kinase OS=Staphylococcus aureus (strain N315)
GN=pyk PE=1 SV=1
Length = 585
Score = 83 bits (204), Expect = 1e-015
Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E+I +NAGM+VAR +FS G+ E H+ +D ++ K K+ A+
Sbjct: 4 TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ N + IIEL+ VI++ ++ E + E + ++ L V G +
Sbjct: 64 LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|Q6GG09|KPYK_STAAR Pyruvate kinase OS=Staphylococcus aureus (strain MRSA252)
GN=pyk PE=3 SV=1
Length = 585
Score = 83 bits (204), Expect = 1e-015
Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E+I +NAGM+VAR +FS G+ E H+ +D ++ K K+ A+
Sbjct: 4 TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ N + IIEL+ VI++ ++ E + E + ++ L V G +
Sbjct: 64 LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|Q6G8M9|KPYK_STAAS Pyruvate kinase OS=Staphylococcus aureus (strain MSSA476)
GN=pyk PE=3 SV=1
Length = 585
Score = 83 bits (204), Expect = 1e-015
Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E+I +NAGM+VAR +FS G+ E H+ +D ++ K K+ A+
Sbjct: 4 TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ N + IIEL+ VI++ ++ E + E + ++ L V G +
Sbjct: 64 LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|Q7A0N4|KPYK_STAAW Pyruvate kinase OS=Staphylococcus aureus (strain MW2)
GN=pyk PE=3 SV=1
Length = 585
Score = 83 bits (204), Expect = 1e-015
Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E+I +NAGM+VAR +FS G+ E H+ +D ++ K K+ A+
Sbjct: 4 TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ N + IIEL+ VI++ ++ E + E + ++ L V G +
Sbjct: 64 LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|Q56301|KPYK_THELI Pyruvate kinase (Fragment) OS=Thermococcus litoralis
GN=pki PE=3 SV=1
Length = 220
Score = 82 bits (200), Expect = 3e-015
Identities = 44/123 (35%), Positives = 75/123 (60%), Gaps = 5/123 (4%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKI+ T+GP S+ E I + AGMSVAR +FS G E H +T++ ++ + ++ A+
Sbjct: 12 TKIIATIGPASKQKESIKKMIKAGMSVARINFSHGTLEEHAKTIETVRDVAEKLERRVAI 71
Query: 251 MLDTVGPELQVVN-RGEKIIELKGDGLVILTPD-QGQEPSSELLPINFDGLSKAVTKGDT 78
+ D G +++V +G+ + KGD +V+ T D +G E + +P+ F L K V+KGDT
Sbjct: 72 LGDLPGLKMRVGKIKGDSVTLRKGDKVVLTTRDIEGDETT---IPVEFKDLPKLVSKGDT 128
Query: 77 VFI 69
+++
Sbjct: 129 IYL 131
>sp|Q27788|KPYK_TRYBO Pyruvate kinase OS=Trypanoplasma borreli GN=PYK PE=3 SV=1
Length = 498
Score = 78 bits (190), Expect = 4e-014
Identities = 44/124 (35%), Positives = 74/124 (59%), Gaps = 6/124 (4%)
Frame = -3
Query: 428 KIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAVM 249
KI+ T+GP S+S EV+ + AG++VAR +FS G EYHQ+T+DN++ A +
Sbjct: 26 KIICTIGPSSQSVEVLKDLMKAGLNVARMNFSHGTYEYHQKTIDNVRKAASELGIHVGIA 85
Query: 248 LDTVGPELQ--VVNRGEKIIELKGDGLVILTPDQ--GQEPSSELLPINFDGLSKAVTKGD 81
LDT GPE++ + G+ +IE VILT D+ ++ ++E +++ ++K V G
Sbjct: 86 LDTKGPEIRTGLFPAGDVVIE--AHKTVILTTDETFKEKGTAEKFYVDYMNITKVVPVGG 143
Query: 80 TVFI 69
+F+
Sbjct: 144 HIFV 147
>sp|P30616|KPYK2_TRYBB Pyruvate kinase 2 OS=Trypanosoma brucei brucei GN=PYK2
PE=3 SV=1
Length = 499
Score = 76 bits (186), Expect = 1e-013
Identities = 42/128 (32%), Positives = 72/128 (56%), Gaps = 2/128 (1%)
Frame = -3
Query: 428 KIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAVM 249
+IV T+GP ++S E + + + +GMSVAR +FS G+ EYHQ T++N++AA +
Sbjct: 23 RIVCTIGPSTQSVEALKNLMKSGMSVARMNFSHGSHEYHQTTINNVRAAAAELGLHIGIA 82
Query: 248 LDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEP--SSELLPINFDGLSKAVTKGDTV 75
LDT GPE++ + + +V +T D E + E I++ L+KAV G ++
Sbjct: 83 LDTKGPEIRTGLFKDGEVTFAPGDIVCVTTDPAYEKVGTKEKFYIDYPQLTKAVPVGGSI 142
Query: 74 FIGQYLFT 51
++ + T
Sbjct: 143 YVDDGVMT 150
>sp|Q54RF5|KPYK_DICDI Pyruvate kinase OS=Dictyostelium discoideum GN=pyk PE=3
SV=1
Length = 507
Score = 76 bits (186), Expect = 1e-013
Identities = 42/133 (31%), Positives = 76/133 (57%), Gaps = 2/133 (1%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GPK+ S E + + GM+V R +FS G +YH + + N+++A++ T K+ A+
Sbjct: 22 TKIVCTIGPKTMSEEALIKLIETGMNVCRLNFSHGTHDYHGQVIKNVRSAMEKTGKIIAI 81
Query: 251 MLDTVGPELQVVNRGEK--IIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDT 78
MLDT GPE++ ++ ++L +++ + Q +S + I++ GL +V G
Sbjct: 82 MLDTKGPEIRTGKIEDRCGYVDLFVGQEILVDTNMNQPGTSFRISIDYKGLLDSVKVGGY 141
Query: 77 VFIGQYLFTGSET 39
+ I + + S T
Sbjct: 142 ILIADGVISLSIT 154
>sp|Q27686|KPYK_LEIME Pyruvate kinase OS=Leishmania mexicana GN=PYK PE=1 SV=1
Length = 499
Score = 75 bits (184), Expect = 2e-013
Identities = 40/122 (32%), Positives = 68/122 (55%), Gaps = 2/122 (1%)
Frame = -3
Query: 428 KIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAVM 249
+I+ T+GP ++S E + + +GMSVAR +FS G+ EYHQ T++N++ A A+
Sbjct: 23 RIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIA 82
Query: 248 LDTVGPELQVVN--RGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTV 75
LDT GPE++ G+ ++E V P + + + I++ LSK V G+ +
Sbjct: 83 LDTKGPEIRTGQFVGGDAVMERGATCYVTTDPAFADKGTKDKFYIDYQNLSKVVRPGNYI 142
Query: 74 FI 69
+I
Sbjct: 143 YI 144
>sp|Q5HNK7|KPYK_STAEQ Pyruvate kinase OS=Staphylococcus epidermidis (strain ATCC
35984 / RP62A) GN=pyk PE=3 SV=1
Length = 585
Score = 75 bits (184), Expect = 2e-013
Identities = 41/121 (33%), Positives = 69/121 (57%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E++ +NAGM+VAR +FS G+ E H+ +D ++ K K +
Sbjct: 4 TKIVCTIGPASESEEMLEKLMNAGMNVARLNFSHGSHEEHKARIDTIRKVAKRLNKTIGL 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ N + +I L+ VI++ ++ E + E + ++ L V G +
Sbjct: 64 LLDTKGPEIRTHNMKDGLIVLEKGKEVIVSMNE-VEGTPEKFSVTYENLINDVNIGSYIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|Q8CS69|KPYK_STAES Pyruvate kinase OS=Staphylococcus epidermidis (strain ATCC
12228) GN=pyk PE=3 SV=1
Length = 585
Score = 75 bits (184), Expect = 2e-013
Identities = 41/121 (33%), Positives = 69/121 (57%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E++ +NAGM+VAR +FS G+ E H+ +D ++ K K +
Sbjct: 4 TKIVCTIGPASESEEMLEKLMNAGMNVARLNFSHGSHEEHKARIDTIRKVAKRLNKTIGL 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ N + +I L+ VI++ ++ E + E + ++ L V G +
Sbjct: 64 LLDTKGPEIRTHNMKDGLIVLEKGKEVIVSMNE-VEGTPEKFSVTYENLINDVNIGSYIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|P30615|KPYK1_TRYBB Pyruvate kinase 1 OS=Trypanosoma brucei brucei GN=PYK1
PE=3 SV=1
Length = 499
Score = 75 bits (183), Expect = 3e-013
Identities = 41/128 (32%), Positives = 71/128 (55%), Gaps = 2/128 (1%)
Frame = -3
Query: 428 KIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAVM 249
+IV T+GP ++S E + + + +GMSVAR +FS G+ EYHQ T++N++AA +
Sbjct: 23 RIVCTIGPSTQSVEALKNLMKSGMSVARMNFSHGSHEYHQTTINNVRAAAAELGLHIGIA 82
Query: 248 LDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEP--SSELLPINFDGLSKAVTKGDTV 75
LDT GPE++ + + +V +T D E + E I++ L+ AV G ++
Sbjct: 83 LDTKGPEIRTGLFKDGEVSFAPGDIVCVTTDPAYEKVGTKEKFYIDYPQLTNAVRPGGSI 142
Query: 74 FIGQYLFT 51
++ + T
Sbjct: 143 YVDDGVMT 150
>sp|Q49YC7|KPYK_STAS1 Pyruvate kinase OS=Staphylococcus saprophyticus subsp.
saprophyticus (strain ATCC 15305 / DSM 20229) GN=pyk PE=3 SV=1
Length = 586
Score = 74 bits (180), Expect = 6e-013
Identities = 40/121 (33%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E++ + AGM+VAR +FS G+ H+ +D ++ K K A+
Sbjct: 4 TKIVCTIGPASESEEMLEKLIKAGMNVARLNFSHGDQAEHKARIDTIRKVSKRLGKTVAI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ N + +IEL+ V ++ + E + E + ++ L V +G +
Sbjct: 64 LLDTKGPEIRTHNMKDGLIELEKGSEVTVSMTE-VEGTPEKFSVTYENLINDVEEGSYIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|Q02499|KPYK_BACST Pyruvate kinase OS=Bacillus stearothermophilus GN=pyk PE=1
SV=2
Length = 587
Score = 74 bits (179), Expect = 8e-013
Identities = 46/128 (35%), Positives = 69/128 (53%), Gaps = 3/128 (2%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S + + + AGM+VAR +FS G+ E H + N++ A K T + A+
Sbjct: 5 TKIVCTIGPASESVDKLVQLMEAGMNVARLNFSHGDHEEHGRRIANIREAAKRTGRTVAI 64
Query: 251 MLDTVGPELQVVNRGEKIIELK-GDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTV 75
+LDT GPE++ N IELK G LVI + P E + + + L V+ G +
Sbjct: 65 LLDTKGPEIRTHNMENGAIELKEGSKLVISMSEVLGTP--EKISVTYPSLIDDVSVGAKI 122
Query: 74 FIGQYLFT 51
+ L +
Sbjct: 123 LLDDGLIS 130
>sp|P51181|KPYK_BACLI Pyruvate kinase OS=Bacillus licheniformis GN=pyk PE=3
SV=1
Length = 585
Score = 73 bits (177), Expect = 1e-012
Identities = 45/132 (34%), Positives = 71/132 (53%), Gaps = 2/132 (1%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E ++ + AGM+VAR +FS G+ E H + N++ A K +
Sbjct: 4 TKIVCTIGPASESVEKLTQLMEAGMNVARLNFSHGDFEEHGARIKNIREAAGKLGKDIGI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ IEL +I++ D+ + + + + +DGL V+ G T+
Sbjct: 64 LLDTKGPEIRTHTMENGSIELAAGSQLIVSMDE-VIGTPDKISVTYDGLIHDVSVGSTIL 122
Query: 71 IGQYLFTGSETT 36
+ L G E T
Sbjct: 123 LDDGL-VGLEVT 133
>sp|P80885|KPYK_BACSU Pyruvate kinase OS=Bacillus subtilis GN=pyk PE=1 SV=2
Length = 585
Score = 72 bits (176), Expect = 2e-012
Identities = 40/121 (33%), Positives = 71/121 (58%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E+++ + +GM+VAR +FS G+ E H + N++ A K K +
Sbjct: 4 TKIVCTIGPASESIEMLTKLMESGMNVARLNFSHGDFEEHGARIKNIREASKKLGKNVGI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ IEL+ +I++ D+ +++ + + ++GL V +G T+
Sbjct: 64 LLDTKGPEIRTHTMENGGIELETGKELIISMDE-VVGTTDKISVTYEGLVHDVEQGSTIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
>sp|P51182|KPYK_BACPY Pyruvate kinase OS=Bacillus psychrophilus GN=pyk PE=3
SV=1
Length = 586
Score = 72 bits (174), Expect = 3e-012
Identities = 37/121 (30%), Positives = 70/121 (57%), Gaps = 1/121 (0%)
Frame = -3
Query: 431 TKIVGTLGPKSRSAEVISSCLNAGMSVARFDFSWGNPEYHQETLDNLKAAVKSTKKLCAV 252
TKIV T+GP S S E++ + AGM+VAR +FS GN H+ +D+++ + K+ +
Sbjct: 4 TKIVCTIGPASESPELLEQLIEAGMNVARLNFSHGNHAEHKARIDSIRKVAREKGKVVGI 63
Query: 251 MLDTVGPELQVVNRGEKIIELKGDGLVILTPDQGQEPSSELLPINFDGLSKAVTKGDTVF 72
+LDT GPE++ + +EL + ++ Q E ++++ +++D L + V +G +
Sbjct: 64 LLDTKGPEIRTHSMMNGKLELVTGQKIDISMTQ-VEGNNDVFSVSYDKLIEDVNEGSVIL 122
Query: 71 I 69
+
Sbjct: 123 L 123
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,133,449,078
Number of Sequences: 462764
Number of Extensions: 22133449078
Number of Successful Extensions: 193841713
Number of sequences better than 0.0: 0
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