BLASTX 7.6.2 Query= RU23213 /QuerySize=1390 (1389 letters) Database: UniProt/Swiss-Prot; 462,764 sequences; 163,773,382 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase A6 OS... 313 3e-084 sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 OS=Rattus nor... 220 2e-056 sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 OS=Homo sap... 219 4e-056 sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 OS=Mus musc... 218 1e-055 sp|Q5R6T1|PDIA6_PONAB Protein disulfide-isomerase A6 OS=Pongo ab... 216 3e-055 sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 OS=Mesocric... 206 3e-052 sp|O22263|PDIA6_ARATH Probable protein disulfide-isomerase A6 OS... 107 3e-022 sp|P11598|PDIA3_RAT Protein disulfide-isomerase A3 OS=Rattus nor... 101 1e-020 sp|P38657|PDIA3_BOVIN Protein disulfide-isomerase A3 OS=Bos taur... 100 3e-020 sp|Q4VIT4|PDIA3_CERAE Protein disulfide-isomerase A3 OS=Cercopit... 99 6e-020 sp|P27773|PDIA3_MOUSE Protein disulfide-isomerase A3 OS=Mus musc... 99 6e-020 sp|P30101|PDIA3_HUMAN Protein disulfide-isomerase A3 OS=Homo sap... 99 8e-020 sp|Q5RDG4|PDIA3_PONAB Protein disulfide-isomerase A3 OS=Pongo ab... 99 8e-020 sp|Q8JG64|PDIA3_CHICK Protein disulfide-isomerase A3 OS=Gallus g... 96 5e-019 sp|P0A4L2|THIO1_ANASO Thioredoxin-1 OS=Anabaena sp. (strain PCC ... 77 2e-013 sp|P0A4L1|THIO1_ANASP Thioredoxin-1 OS=Anabaena sp. (strain PCC ... 77 2e-013 sp|Q4UNK3|THIO_RICFE Thioredoxin OS=Rickettsia felis GN=trxA PE=... 76 4e-013 sp|P0AA27|THIO_ECO57 Thioredoxin-1 OS=Escherichia coli O157:H7 G... 75 7e-013 sp|P0AA26|THIO_ECOL6 Thioredoxin-1 OS=Escherichia coli O6 GN=trx... 75 7e-013 sp|P0AA25|THIO_ECOLI Thioredoxin-1 OS=Escherichia coli (strain K... 75 7e-013 sp|P0AA29|THIO_SALTI Thioredoxin-1 OS=Salmonella typhi GN=trxA P... 75 7e-013 sp|P0AA28|THIO_SALTY Thioredoxin-1 OS=Salmonella typhimurium GN=... 75 7e-013 sp|P0AA30|THIO_SHIFL Thioredoxin-1 OS=Shigella flexneri GN=trxA ... 75 7e-013 sp|P10472|THIO_CHLLT Thioredoxin OS=Chlorobium limicola f.sp. th... 74 2e-012 >sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase A6 OS=Caenorhabditis elegans GN=tag-320 PE=2 SV=1 Length = 440 Score = 313 bits (800), Expect = 3e-084 Identities = 160/397 (40%), Positives = 232/397 (58%), Gaps = 16/397 (4%) Frame = +1 Query: 184 LYGPSSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVA 363 +Y V++LT +NF+SKV++S+ + +VEF+APWCGHC++L P ++KAA+ LKGVA V Sbjct: 19 MYSKKDDVVELTEANFQSKVINSDDIWIVEFYAPWCGHCKSLVPEYKKAASALKGVAKVG 78 Query: 364 ALDADAHKSLAQEYGIRGFPTIKVF-VPGQPPVDYQGAREVKPIAEFAVKQIKALLKDRL 540 A+D H+S+ Y ++GFPT+K+F + P DY G R + IA+ + + K + RL Sbjct: 79 AVDMTQHQSVGGPYNVQGFPTLKIFGADKKKPTDYNGQRTAQAIADSVLAEAKKAVSARL 138 Query: 541 SGKATGGSSEKP-----------EPNASVELNSQNFDELVVKSKDLWVVEFFAPWCGHCK 687 GK++G SS N VEL NF++LV+ SKD+W+VEFFAPWCGHCK Sbjct: 139 GGKSSGSSSSGSGSGSGKRGGGGSGNEVVELTDANFEDLVLNSKDIWLVEFFAPWCGHCK 198 Query: 688 KLAPEWXXXXXXXXXXXXXXHVDCDAEKSLMSRFNVQGFPTILVF--GADKDSPVPYEGA 861 L P+W +D + ++F ++GFPTI F G+D Y+G Sbjct: 199 SLEPQWKAAASELKGKVRLGALDATVHTVVANKFAIRGFPTIKYFAPGSDVSDAQDYDGG 258 Query: 862 RTASAIESFSLEQLETNVAPPEVTELTGPDVLEEKCGSAAICFVAFLPDILDSKAEGRNK 1041 R +S I +++ + + N+ PEV E V+E+ C +C AFLP ILD ++E RN Sbjct: 259 RQSSDIVAWASARAQENMPAPEVFEGINQQVVEDACKEKQLCIFAFLPHILDCQSECRNN 318 Query: 1042 YLQQLLSVAEKFKKSPYSYVWAAAGKQQDLENRVGVGGYGYPALVALNVKKGAYAPLKSA 1221 YL L +EKFKK+ + ++W Q LE VGG+GYPA+ ALN +K YA LK + Sbjct: 319 YLAMLKEQSEKFKKNLWGWIWVEGAAQPALEESFEVGGFGYPAMTALNFRKNKYAVLKGS 378 Query: 1222 FELDQIIEFVREA--GRGGKGNLPLNGTPNIVKSEPW 1326 F D I EF+R+ G+G +L +G P I K+E W Sbjct: 379 FGKDGIHEFLRDLSYGKGRTSSLRGDGFPKIQKTEKW 415 Score = 106 bits (262), Expect = 6e-022 Identities = 55/135 (40%), Positives = 70/135 (51%), Gaps = 3/135 (2%) Frame = +1 Query: 514 IKALLKDRLSGKATGGSSEKPEPNASVELNSQNFDELVVKSKDLWVVEFFAPWCGHCKKL 693 IK LL G S+K + VEL NF V+ S D+W+VEF+APWCGHCK L Sbjct: 4 IKLLLASLAITSVCGMYSKKDD---VVELTEANFQSKVINSDDIWIVEFYAPWCGHCKSL 60 Query: 694 APEWXXXXXXXXXXXXXXHVDCDAEKSLMSRFNVQGFPTILVFGADKDSPVPYEGARTAS 873 PE+ VD +S+ +NVQGFPT+ +FGADK P Y G RTA Sbjct: 61 VPEYKKAASALKGVAKVGAVDMTQHQSVGGPYNVQGFPTLKIFGADKKKPTDYNGQRTAQ 120 Query: 874 AIESFSLEQLETNVA 918 AI L + + V+ Sbjct: 121 AIADSVLAEAKKAVS 135 >sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 OS=Rattus norvegicus GN=Pdia6 PE=1 SV=2 Length = 440 Score = 220 bits (559), Expect = 2e-056 Identities = 114/279 (40%), Positives = 158/279 (56%), Gaps = 9/279 (3%) Frame = +1 Query: 514 IKALLKDRLSGKATG--GSSEKPEPNASVELNSQNFDELVVKSKDLWVVEFFAPWCGHCK 687 +K L R G ++G G + VEL FD+ V+ S+D+W+VEF+APWCGHCK Sbjct: 135 VKDRLGGRSGGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCK 194 Query: 688 KLAPEWXXXXX----XXXXXXXXXHVDCDAEKSLMSRFNVQGFPTILVFGADKDSPVPYE 855 L PEW VD + L SR+ ++GFPTI +F +SPV Y+ Sbjct: 195 NLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIKGFPTIKIF-QKGESPVDYD 253 Query: 856 GARTASAIESFSLEQLETNVAPPEVTELTGPDVLEEKCGSAAICFVAFLPDILDSKAEGR 1035 G RT S I S +L+ N PPE+ E+ D+ ++ C +C VA LP ILD+ A GR Sbjct: 254 GGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKKTCEEHQLCVVAVLPHILDTGATGR 313 Query: 1036 NKYLQQLLSVAEKFKKSPYSYVWAAAGKQQDLENRVGVGGYGYPALVALNVKKGAYAPLK 1215 N YL+ LL +A+K+KK + ++W AG Q +LEN +G+GG+GYPA+ A+N +K +A LK Sbjct: 314 NSYLEVLLKLADKYKKKMWGWLWTEAGAQYELENALGIGGFGYPAMAAINARKMKFALLK 373 Query: 1216 SAFELDQIIEFVREAGRGGKGNLPLNG--TPNIVKSEPW 1326 +F I EF+RE G P+ G PNI EPW Sbjct: 374 GSFSEQGINEFLRELSFGRGSTAPVGGGSFPNITPREPW 412 Score = 195 bits (495), Expect = 6e-049 Identities = 94/182 (51%), Positives = 125/182 (68%), Gaps = 7/182 (3%) Frame = +1 Query: 181 ALYGPSSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATV 360 ALY S V++LTPSNF +V+ S+ + LVEF+APWCGHCQ LTP W+KAA+ LK V V Sbjct: 19 ALYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAASALKDVVKV 78 Query: 361 AALDADAHKSLAQEYGIRGFPTIKVFVPGQ-PPVDYQGAREVKPIAEFAVKQIKALLKDR 537 A++AD H+SL +YG++GFPTIK+F + P DYQG R + I + A+ ++ L+KDR Sbjct: 79 GAVNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDR 138 Query: 538 LSGKATGGSSEKPEPNAS------VELNSQNFDELVVKSKDLWVVEFFAPWCGHCKKLAP 699 L G++ G SS K S VEL FD+ V+ S+D+W+VEF+APWCGHCK L P Sbjct: 139 LGGRSGGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEP 198 Query: 700 EW 705 EW Sbjct: 199 EW 200 >sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 OS=Homo sapiens GN=PDIA6 PE=1 SV=1 Length = 440 Score = 219 bits (557), Expect = 4e-056 Identities = 113/279 (40%), Positives = 159/279 (56%), Gaps = 9/279 (3%) Frame = +1 Query: 514 IKALLKDRLSGKATG--GSSEKPEPNASVELNSQNFDELVVKSKDLWVVEFFAPWCGHCK 687 +K L R G ++G G S+ +EL +FD+ V+ S+D+W+VEF+APWCGHCK Sbjct: 135 VKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCK 194 Query: 688 KLAPEWXXXXX----XXXXXXXXXHVDCDAEKSLMSRFNVQGFPTILVFGADKDSPVPYE 855 L PEW VD + L SR+ ++GFPTI +F +SPV Y+ Sbjct: 195 NLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIF-QKGESPVDYD 253 Query: 856 GARTASAIESFSLEQLETNVAPPEVTELTGPDVLEEKCGSAAICFVAFLPDILDSKAEGR 1035 G RT S I S +L+ N PPE+ E+ D+ + C +C VA LP ILD+ A GR Sbjct: 254 GGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGR 313 Query: 1036 NKYLQQLLSVAEKFKKSPYSYVWAAAGKQQDLENRVGVGGYGYPALVALNVKKGAYAPLK 1215 N YL+ LL +A+K+KK + ++W AG Q +LE +G+GG+GYPA+ A+N +K +A LK Sbjct: 314 NSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINARKMKFALLK 373 Query: 1216 SAFELDQIIEFVREAGRGGKGNLPLNG--TPNIVKSEPW 1326 +F I EF+RE G P+ G P IV+ EPW Sbjct: 374 GSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPW 412 Score = 197 bits (499), Expect = 2e-049 Identities = 94/183 (51%), Positives = 126/183 (68%), Gaps = 7/183 (3%) Frame = +1 Query: 178 DALYGPSSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVAT 357 + LY S V++LTPSNF +V+ S+ + LVEF+APWCGHCQ LTP W+KAAT LK V Sbjct: 18 NGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVK 77 Query: 358 VAALDADAHKSLAQEYGIRGFPTIKVFVPGQ-PPVDYQGAREVKPIAEFAVKQIKALLKD 534 V A+DAD H SL +YG++GFPTIK+F + P DYQG R + I + A+ ++ L+KD Sbjct: 78 VGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKD 137 Query: 535 RLSGKATGGSSEKPEPNAS------VELNSQNFDELVVKSKDLWVVEFFAPWCGHCKKLA 696 RL G++ G SS K + S +EL +FD+ V+ S+D+W+VEF+APWCGHCK L Sbjct: 138 RLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLE 197 Query: 697 PEW 705 PEW Sbjct: 198 PEW 200 >sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 OS=Mus musculus GN=Pdia6 PE=1 SV=3 Length = 440 Score = 218 bits (553), Expect = 1e-055 Identities = 113/279 (40%), Positives = 157/279 (56%), Gaps = 9/279 (3%) Frame = +1 Query: 514 IKALLKDRLSGKATG--GSSEKPEPNASVELNSQNFDELVVKSKDLWVVEFFAPWCGHCK 687 +K L R G ++G G + VEL FD+ V+ S+D+W+VEF+APWCGHCK Sbjct: 135 VKDRLGGRSGGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCK 194 Query: 688 KLAPEWXXXXX----XXXXXXXXXHVDCDAEKSLMSRFNVQGFPTILVFGADKDSPVPYE 855 L PEW VD + L SR+ ++GFPTI +F +SPV Y+ Sbjct: 195 NLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIKGFPTIKIF-QKGESPVDYD 253 Query: 856 GARTASAIESFSLEQLETNVAPPEVTELTGPDVLEEKCGSAAICFVAFLPDILDSKAEGR 1035 G RT S I S +L+ N PPE+ E+ D+ ++ C +C VA LP ILD+ A GR Sbjct: 254 GGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKKTCEEHQLCVVAVLPHILDTGAAGR 313 Query: 1036 NKYLQQLLSVAEKFKKSPYSYVWAAAGKQQDLENRVGVGGYGYPALVALNVKKGAYAPLK 1215 N YL+ LL +A+K+KK + ++W AG Q +LEN +G+GG+GYPA+ A+N +K +A LK Sbjct: 314 NSYLEVLLKLADKYKKKMWGWLWTEAGAQYELENALGIGGFGYPAMAAINARKMKFALLK 373 Query: 1216 SAFELDQIIEFVREAGRGGKGNLPLNG--TPNIVKSEPW 1326 +F I EF+RE G P+ G P I EPW Sbjct: 374 GSFSEQGINEFLRELSFGRGSTAPVGGGSFPTITPREPW 412 Score = 195 bits (494), Expect = 8e-049 Identities = 94/181 (51%), Positives = 124/181 (68%), Gaps = 7/181 (3%) Frame = +1 Query: 184 LYGPSSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVA 363 LY S V++LTPSNF +V+ S+ + LVEF+APWCGHCQ LTP W+KAAT LK V V Sbjct: 20 LYSSSDDVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVG 79 Query: 364 ALDADAHKSLAQEYGIRGFPTIKVFVPGQ-PPVDYQGAREVKPIAEFAVKQIKALLKDRL 540 A++AD H+SL +YG++GFPTIK+F + P DYQG R + I + A+ ++ L+KDRL Sbjct: 80 AVNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRL 139 Query: 541 SGKATGGSSEKPEPNAS------VELNSQNFDELVVKSKDLWVVEFFAPWCGHCKKLAPE 702 G++ G SS K S VEL FD+ V+ S+D+W+VEF+APWCGHCK L PE Sbjct: 140 GGRSGGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPE 199 Query: 703 W 705 W Sbjct: 200 W 200 >sp|Q5R6T1|PDIA6_PONAB Protein disulfide-isomerase A6 OS=Pongo abelii GN=PDIA6 PE=2 SV=1 Length = 440 Score = 216 bits (550), Expect = 3e-055 Identities = 111/279 (39%), Positives = 159/279 (56%), Gaps = 9/279 (3%) Frame = +1 Query: 514 IKALLKDRLSGKATG--GSSEKPEPNASVELNSQNFDELVVKSKDLWVVEFFAPWCGHCK 687 +K L + G ++G G S+ +EL +FD+ V+ S+D+W+VEF+APWCGHCK Sbjct: 135 VKDRLGGQSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCK 194 Query: 688 KLAPEWXXXXX----XXXXXXXXXHVDCDAEKSLMSRFNVQGFPTILVFGADKDSPVPYE 855 L PEW VD + L SR+ ++GFPTI +F +SPV Y+ Sbjct: 195 NLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIF-QKGESPVDYD 253 Query: 856 GARTASAIESFSLEQLETNVAPPEVTELTGPDVLEEKCGSAAICFVAFLPDILDSKAEGR 1035 G RT S I S +L+ N PPE+ E+ D+ + C +C V+ LP ILD+ A GR Sbjct: 254 GGRTRSDIVSRALDLFSDNAPPPELLEIISEDIAKRTCEEHQLCVVSVLPHILDTGAAGR 313 Query: 1036 NKYLQQLLSVAEKFKKSPYSYVWAAAGKQQDLENRVGVGGYGYPALVALNVKKGAYAPLK 1215 N YL+ LL +A+K+KK + ++W AG Q +LE +G+GG+GYPA+ A+N +K +A LK Sbjct: 314 NSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINARKMKFALLK 373 Query: 1216 SAFELDQIIEFVREAGRGGKGNLPLNG--TPNIVKSEPW 1326 +F I EF+RE G P+ G P IV+ EPW Sbjct: 374 GSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPW 412 Score = 196 bits (498), Expect = 3e-049 Identities = 94/183 (51%), Positives = 126/183 (68%), Gaps = 7/183 (3%) Frame = +1 Query: 178 DALYGPSSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVAT 357 + LY S V++LTPSNF +V+ S+ + LVEF+APWCGHCQ LTP W+KAAT LK V Sbjct: 18 NGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVK 77 Query: 358 VAALDADAHKSLAQEYGIRGFPTIKVFVPGQ-PPVDYQGAREVKPIAEFAVKQIKALLKD 534 V A+DAD H SL +YG++GFPTIK+F + P DYQG R + I + A+ ++ L+KD Sbjct: 78 VGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKD 137 Query: 535 RLSGKATGGSSEKPEPNAS------VELNSQNFDELVVKSKDLWVVEFFAPWCGHCKKLA 696 RL G++ G SS K + S +EL +FD+ V+ S+D+W+VEF+APWCGHCK L Sbjct: 138 RLGGQSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLE 197 Query: 697 PEW 705 PEW Sbjct: 198 PEW 200 >sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 OS=Mesocricetus auratus GN=PDIA6 PE=1 SV=1 Length = 439 Score = 206 bits (524), Expect = 3e-052 Identities = 109/279 (39%), Positives = 154/279 (55%), Gaps = 10/279 (3%) Frame = +1 Query: 514 IKALLKDRLSGKATG--GSSEKPEPNASVELNSQNFDELVVKSKDLWVVEFFAPWCGHCK 687 +K L R G ++G G + +EL FD+ V+ S D+W+VEF+APWCGHCK Sbjct: 135 VKDRLSGRSGGYSSGKQGRGDSSSKKDVIELTDDTFDKNVLDSDDVWMVEFYAPWCGHCK 194 Query: 688 KLAPEWXXXXX----XXXXXXXXXHVDCDAEKSLMSRFNVQGFPTILVFGADKDSPVPYE 855 L PEW VD + L +R+ ++GFPTI +F ++PV Y+ Sbjct: 195 NLEPEWATAATEVKEQTKGKVKLAAVDATVNQVLANRYGIRGFPTIKIF-QKGEAPVDYD 253 Query: 856 GARTASAIESFSLEQLETNVAPPEVTELTGPDVLEEKCGSAAICFVAFLPDILDSKAEGR 1035 G RT S I S +L+ N PPE+ E+ DV ++ C +C VA LP ILD+ A R Sbjct: 254 GGRTRSDIVSRALDLFSDNAPPPELLEIINEDVAKKMCEEHQLCVVAVLPHILDTGA-AR 312 Query: 1036 NKYLQQLLSVAEKFKKSPYSYVWAAAGKQQDLENRVGVGGYGYPALVALNVKKGAYAPLK 1215 N YL+ LL +A+K+KK + ++W AG Q +LEN +G+GG+GYPA+ +N +K +A LK Sbjct: 313 NSYLEILLKLADKYKKKMWGWLWTEAGAQSELENALGIGGFGYPAMARINARKMKFALLK 372 Query: 1216 SAFELDQIIEFVREAGRGGKGNLPLNG--TPNIVKSEPW 1326 +F I EF+RE G P+ G P I EPW Sbjct: 373 GSFSEQGINEFLRELSFGRASTAPVGGGSFPAITAREPW 411 Score = 200 bits (506), Expect = 3e-050 Identities = 96/181 (53%), Positives = 124/181 (68%), Gaps = 7/181 (3%) Frame = +1 Query: 184 LYGPSSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVA 363 LY S V++LTPSNF +V+ SN + LVEF+APWCGHCQ LTP W+KAAT LK V V Sbjct: 20 LYSSSDDVIELTPSNFNREVIQSNSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVG 79 Query: 364 ALDADAHKSLAQEYGIRGFPTIKVFVPGQ-PPVDYQGAREVKPIAEFAVKQIKALLKDRL 540 A+DAD H+SL +YG++GFPTIK+F + P DYQG R + I + A+ ++ L+KDRL Sbjct: 80 AVDADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRL 139 Query: 541 SGKATGGSSEKPEPNAS------VELNSQNFDELVVKSKDLWVVEFFAPWCGHCKKLAPE 702 SG++ G SS K S +EL FD+ V+ S D+W+VEF+APWCGHCK L PE Sbjct: 140 SGRSGGYSSGKQGRGDSSSKKDVIELTDDTFDKNVLDSDDVWMVEFYAPWCGHCKNLEPE 199 Query: 703 W 705 W Sbjct: 200 W 200 >sp|O22263|PDIA6_ARATH Probable protein disulfide-isomerase A6 OS=Arabidopsis thaliana GN=At2g47470 PE=1 SV=1 Length = 361 Score = 107 bits (265), Expect = 3e-022 Identities = 63/150 (42%), Positives = 82/150 (54%), Gaps = 14/150 (9%) Frame = +1 Query: 205 VLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLK---GVATVAALDA 375 V+ LTP NF VLD N+ VLVEF+APWCGHC++L P +EK ATV K GV +A LDA Sbjct: 143 VVVLTPDNFDEIVLDQNKDVLVEFYAPWCGHCKSLAPTYEKVATVFKQEEGV-VIANLDA 201 Query: 376 DAHKSLAQEYGIRGFPTIKVF-VPGQPPVDYQGAREVKPIAEFAVKQIKALLKDRLSGKA 552 DAHK+L ++YG+ GFPT+K F + DY G R++ F + SG + Sbjct: 202 DAHKALGEKYGVSGFPTLKFFPKDNKAGHDYDGGRDLDDFVSFI---------NEKSGTS 252 Query: 553 TGGSSEKPEPNASVELNSQNFDELVVKSKD 642 + VE ELV S+D Sbjct: 253 RDSKGQLTSKAGIVESLDALVKELVAASED 282 >sp|P11598|PDIA3_RAT Protein disulfide-isomerase A3 OS=Rattus norvegicus GN=Pdia3 PE=1 SV=2 Length = 505 Score = 101 bits (251), Expect = 1e-020 Identities = 51/113 (45%), Positives = 70/113 (61%), Gaps = 2/113 (1%) Frame = +1 Query: 181 ALYGPSSPVLQLTPSNFKSKVLD--SNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVA 354 AL +S VL+LT NF+S+V D S ++LVEFFAPWCGHC+ L P +E AAT LKG+ Sbjct: 19 ALLASASDVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIV 78 Query: 355 TVAALDADAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEFAVKQ 513 +A +D A+ + +YG+ G+PT+K+F G+ Y G R I KQ Sbjct: 79 PLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQ 131 >sp|P38657|PDIA3_BOVIN Protein disulfide-isomerase A3 OS=Bos taurus GN=PDIA3 PE=2 SV=1 Length = 505 Score = 100 bits (248), Expect = 3e-020 Identities = 48/108 (44%), Positives = 69/108 (63%), Gaps = 2/108 (1%) Frame = +1 Query: 196 SSPVLQLTPSNFKSKVLD--SNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAAL 369 +S VL+LT NF+S++ D S+ ++LVEFFAPWCGHC+ L P +E AAT LKG+ +A + Sbjct: 24 ASDVLELTDDNFESRITDTGSSGLMLVEFFAPWCGHCKKLAPEYEAAATRLKGIVPLAKV 83 Query: 370 DADAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEFAVKQ 513 D A+ + +YG+ G+PT+K+F G+ Y G R I KQ Sbjct: 84 DCTANTNTCNKYGVSGYPTLKIFRDGEESGAYDGPRTADGIVSHLKKQ 131 >sp|Q4VIT4|PDIA3_CERAE Protein disulfide-isomerase A3 OS=Cercopithecus aethiops GN=PDIA3 PE=2 SV=1 Length = 505 Score = 99 bits (245), Expect = 6e-020 Identities = 49/108 (45%), Positives = 68/108 (62%), Gaps = 2/108 (1%) Frame = +1 Query: 196 SSPVLQLTPSNFKSKVLD--SNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAAL 369 +S VL+LT NF+S+V D S ++LVEFFAPWCGHC+ L P +E AAT LKG+ +A + Sbjct: 24 ASDVLELTDDNFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKV 83 Query: 370 DADAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEFAVKQ 513 D A+ + +YG+ G+PT+K+F G+ Y G R I KQ Sbjct: 84 DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQ 131 >sp|P27773|PDIA3_MOUSE Protein disulfide-isomerase A3 OS=Mus musculus GN=Pdia3 PE=1 SV=2 Length = 505 Score = 99 bits (245), Expect = 6e-020 Identities = 49/108 (45%), Positives = 68/108 (62%), Gaps = 2/108 (1%) Frame = +1 Query: 196 SSPVLQLTPSNFKSKVLD--SNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAAL 369 +S VL+LT NF+S+V D S ++LVEFFAPWCGHC+ L P +E AAT LKG+ +A + Sbjct: 24 ASDVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKV 83 Query: 370 DADAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEFAVKQ 513 D A+ + +YG+ G+PT+K+F G+ Y G R I KQ Sbjct: 84 DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQ 131 >sp|P30101|PDIA3_HUMAN Protein disulfide-isomerase A3 OS=Homo sapiens GN=PDIA3 PE=1 SV=4 Length = 505 Score = 99 bits (244), Expect = 8e-020 Identities = 48/108 (44%), Positives = 68/108 (62%), Gaps = 2/108 (1%) Frame = +1 Query: 196 SSPVLQLTPSNFKSKVLD--SNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAAL 369 +S VL+LT NF+S++ D S ++LVEFFAPWCGHC+ L P +E AAT LKG+ +A + Sbjct: 24 ASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKV 83 Query: 370 DADAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEFAVKQ 513 D A+ + +YG+ G+PT+K+F G+ Y G R I KQ Sbjct: 84 DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQ 131 >sp|Q5RDG4|PDIA3_PONAB Protein disulfide-isomerase A3 OS=Pongo abelii GN=PDIA3 PE=2 SV=1 Length = 505 Score = 99 bits (244), Expect = 8e-020 Identities = 48/108 (44%), Positives = 68/108 (62%), Gaps = 2/108 (1%) Frame = +1 Query: 196 SSPVLQLTPSNFKSKVLD--SNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAAL 369 +S VL+LT NF+S++ D S ++LVEFFAPWCGHC+ L P +E AAT LKG+ +A + Sbjct: 24 ASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKV 83 Query: 370 DADAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEFAVKQ 513 D A+ + +YG+ G+PT+K+F G+ Y G R I KQ Sbjct: 84 DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQ 131 >sp|Q8JG64|PDIA3_CHICK Protein disulfide-isomerase A3 OS=Gallus gallus GN=PDIA3 PE=2 SV=1 Length = 505 Score = 96 bits (237), Expect = 5e-019 Identities = 45/111 (40%), Positives = 68/111 (61%) Frame = +1 Query: 181 ALYGPSSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATV 360 AL +S V++L+ ++F+S + + +VLVEFFAPWCGHC+ L P +E AAT LKG+ + Sbjct: 19 ALSAGASDVVELSDADFESGLAERPGLVLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPL 78 Query: 361 AALDADAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEFAVKQ 513 +D A+ + +YG+ G+PT+K+F G+ Y G R I KQ Sbjct: 79 VKVDCTANSNTCNKYGVSGYPTLKIFRDGEESGTYDGPRTADGIVSHLKKQ 129 >sp|P0A4L2|THIO1_ANASO Thioredoxin-1 OS=Anabaena sp. (strain PCC 7119) GN=trxA PE=1 SV=2 Length = 107 Score = 77 bits (188), Expect = 2e-013 Identities = 35/84 (41%), Positives = 53/84 (63%) Frame = +1 Query: 199 SPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAALDAD 378 S Q+T S FK +VLDS+ VLV+F+APWCG C+ + P+ ++ A +G V ++ D Sbjct: 2 SAAAQVTDSTFKQEVLDSDVPVLVDFWAPWCGPCRMVAPVVDEIAQQYEGKIKVVKVNTD 61 Query: 379 AHKSLAQEYGIRGFPTIKVFVPGQ 450 + +A +YGIR PT+ +F GQ Sbjct: 62 ENPQVASQYGIRSIPTLMIFKGGQ 85 >sp|P0A4L1|THIO1_ANASP Thioredoxin-1 OS=Anabaena sp. (strain PCC 7120) GN=trxA PE=3 SV=2 Length = 107 Score = 77 bits (188), Expect = 2e-013 Identities = 35/84 (41%), Positives = 53/84 (63%) Frame = +1 Query: 199 SPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAALDAD 378 S Q+T S FK +VLDS+ VLV+F+APWCG C+ + P+ ++ A +G V ++ D Sbjct: 2 SAAAQVTDSTFKQEVLDSDVPVLVDFWAPWCGPCRMVAPVVDEIAQQYEGKIKVVKVNTD 61 Query: 379 AHKSLAQEYGIRGFPTIKVFVPGQ 450 + +A +YGIR PT+ +F GQ Sbjct: 62 ENPQVASQYGIRSIPTLMIFKGGQ 85 >sp|Q4UNK3|THIO_RICFE Thioredoxin OS=Rickettsia felis GN=trxA PE=3 SV=2 Length = 105 Score = 76 bits (186), Expect = 4e-013 Identities = 38/101 (37%), Positives = 61/101 (60%) Frame = +1 Query: 214 LTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAALDADAHKSL 393 +T S+FK +VL+S+ VLV+F+A WCG C+ LTPI ++ + LKG V ++ D + ++ Sbjct: 5 VTDSSFKKEVLESDLPVLVDFWAEWCGPCKMLTPIIDEISKELKGKVKVLKMNIDENPNI 64 Query: 394 AQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEFAVKQI 516 EYGIR PTI +F G+ G ++ + ++ K I Sbjct: 65 PSEYGIRSIPTIMLFKNGEQKDTKIGLQQKNSLLDWINKSI 105 >sp|P0AA27|THIO_ECO57 Thioredoxin-1 OS=Escherichia coli O157:H7 GN=trxA PE=3 SV=2 Length = 109 Score = 75 bits (184), Expect = 7e-013 Identities = 37/102 (36%), Positives = 58/102 (56%) Frame = +1 Query: 196 SSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAALDA 375 S ++ LT +F + VL ++ +LV+F+A WCG C+ + PI ++ A +G TVA L+ Sbjct: 2 SDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNI 61 Query: 376 DAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEF 501 D + A +YGIRG PT+ +F G+ GA + EF Sbjct: 62 DQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEF 103 >sp|P0AA26|THIO_ECOL6 Thioredoxin-1 OS=Escherichia coli O6 GN=trxA PE=3 SV=2 Length = 109 Score = 75 bits (184), Expect = 7e-013 Identities = 37/102 (36%), Positives = 58/102 (56%) Frame = +1 Query: 196 SSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAALDA 375 S ++ LT +F + VL ++ +LV+F+A WCG C+ + PI ++ A +G TVA L+ Sbjct: 2 SDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNI 61 Query: 376 DAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEF 501 D + A +YGIRG PT+ +F G+ GA + EF Sbjct: 62 DQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEF 103 >sp|P0AA25|THIO_ECOLI Thioredoxin-1 OS=Escherichia coli (strain K12) GN=trxA PE=1 SV=2 Length = 109 Score = 75 bits (184), Expect = 7e-013 Identities = 37/102 (36%), Positives = 58/102 (56%) Frame = +1 Query: 196 SSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAALDA 375 S ++ LT +F + VL ++ +LV+F+A WCG C+ + PI ++ A +G TVA L+ Sbjct: 2 SDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNI 61 Query: 376 DAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEF 501 D + A +YGIRG PT+ +F G+ GA + EF Sbjct: 62 DQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEF 103 >sp|P0AA29|THIO_SALTI Thioredoxin-1 OS=Salmonella typhi GN=trxA PE=3 SV=2 Length = 109 Score = 75 bits (184), Expect = 7e-013 Identities = 37/102 (36%), Positives = 58/102 (56%) Frame = +1 Query: 196 SSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAALDA 375 S ++ LT +F + VL ++ +LV+F+A WCG C+ + PI ++ A +G TVA L+ Sbjct: 2 SDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNI 61 Query: 376 DAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEF 501 D + A +YGIRG PT+ +F G+ GA + EF Sbjct: 62 DQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEF 103 >sp|P0AA28|THIO_SALTY Thioredoxin-1 OS=Salmonella typhimurium GN=trxA PE=3 SV=2 Length = 109 Score = 75 bits (184), Expect = 7e-013 Identities = 37/102 (36%), Positives = 58/102 (56%) Frame = +1 Query: 196 SSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAALDA 375 S ++ LT +F + VL ++ +LV+F+A WCG C+ + PI ++ A +G TVA L+ Sbjct: 2 SDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNI 61 Query: 376 DAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEF 501 D + A +YGIRG PT+ +F G+ GA + EF Sbjct: 62 DQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEF 103 >sp|P0AA30|THIO_SHIFL Thioredoxin-1 OS=Shigella flexneri GN=trxA PE=3 SV=2 Length = 109 Score = 75 bits (184), Expect = 7e-013 Identities = 37/102 (36%), Positives = 58/102 (56%) Frame = +1 Query: 196 SSPVLQLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAALDA 375 S ++ LT +F + VL ++ +LV+F+A WCG C+ + PI ++ A +G TVA L+ Sbjct: 2 SDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNI 61 Query: 376 DAHKSLAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAEF 501 D + A +YGIRG PT+ +F G+ GA + EF Sbjct: 62 DQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEF 103 >sp|P10472|THIO_CHLLT Thioredoxin OS=Chlorobium limicola f.sp. thiosulfatophilum GN=trxA PE=1 SV=5 Length = 108 Score = 74 bits (181), Expect = 2e-012 Identities = 36/96 (37%), Positives = 58/96 (60%) Frame = +1 Query: 211 QLTPSNFKSKVLDSNRVVLVEFFAPWCGHCQALTPIWEKAATVLKGVATVAALDADAHKS 390 + T NF++++LDS++ VLV+F+A WCG C L P+ E+ A +G A +A L+ D + + Sbjct: 6 EATDKNFQTEILDSDKAVLVDFWASWCGPCMMLGPVIEQLADDYEGKAIIAKLNVDENPN 65 Query: 391 LAQEYGIRGFPTIKVFVPGQPPVDYQGAREVKPIAE 498 +A +YGIR PT+ + G+ GA IA+ Sbjct: 66 IAGQYGIRSIPTMLIIKGGKVVDQMVGALPKNMIAK 101 Database: UniProt/Swiss-Prot Posted date: Thu Apr 23 14:22:33 2009 Number of letters in database: 163,773,382 Number of sequences in database: 462,764 Lambda K H 0.267 0.041 0.140 Gapped Lambda K H 0.267 0.041 0.140 Matrix: blosum62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,594,585,930 Number of Sequences: 462764 Number of Extensions: 24594585930 Number of Successful Extensions: 241005048 Number of sequences better than 0.0: 0 |