BLASTX 7.6.2
Query= RU26659 /QuerySize=1827
(1826 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q56WD9|THIK2_ARATH 3-ketoacyl-CoA thiolase 2, peroxisomal OS=... 716 1e-205
sp|Q8LF48|THIK1_ARATH 3-ketoacyl-CoA thiolase 1, peroxisomal OS=... 659 2e-188
sp|Q570C8|THIK5_ARATH 3-ketoacyl-CoA thiolase 5, peroxisomal OS=... 583 1e-165
sp|Q921H8|THIKA_MOUSE 3-ketoacyl-CoA thiolase A, peroxisomal OS=... 416 4e-115
sp|P07871|THIKB_RAT 3-ketoacyl-CoA thiolase B, peroxisomal OS=Ra... 413 2e-114
sp|Q8VCH0|THIKB_MOUSE 3-ketoacyl-CoA thiolase B, peroxisomal OS=... 413 3e-114
sp|P09110|THIK_HUMAN 3-ketoacyl-CoA thiolase, peroxisomal OS=Hom... 411 1e-113
sp|P21775|THIKA_RAT 3-ketoacyl-CoA thiolase A, peroxisomal OS=Ra... 409 3e-113
sp|Q05493|THIK_YARLI 3-ketoacyl-CoA thiolase, peroxisomal OS=Yar... 353 2e-096
sp|O32177|FADA_BACSU 3-ketoacyl-CoA thiolase OS=Bacillus subtili... 309 7e-083
sp|P76461|ATOB_ECOLI Acetyl-CoA acetyltransferase OS=Escherichia... 242 8e-063
sp|Q9BWD1|THIC_HUMAN Acetyl-CoA acetyltransferase, cytosolic OS=... 231 2e-059
sp|P27796|THIK_YEAST 3-ketoacyl-CoA thiolase, peroxisomal OS=Sac... 227 3e-058
sp|Q8BWT1|THIM_MOUSE 3-ketoacyl-CoA thiolase, mitochondrial OS=M... 223 4e-057
sp|P13437|THIM_RAT 3-ketoacyl-CoA thiolase, mitochondrial OS=Rat... 221 1e-056
sp|Q3T0R7|THIM_BOVIN 3-ketoacyl-CoA thiolase, mitochondrial OS=B... 220 3e-056
sp|P14611|THIL_RALEH Acetyl-CoA acetyltransferase OS=Ralstonia e... 198 2e-049
sp|Q8CAY6|THIC_MOUSE Acetyl-CoA acetyltransferase, cytosolic OS=... 171 2e-041
sp|P45855|THL_BACSU Acetyl-CoA acetyltransferase OS=Bacillus sub... 169 7e-041
sp|Q5XI22|THIC_RAT Acetyl-CoA acetyltransferase, cytosolic OS=Ra... 168 1e-040
sp|Q8S4Y1|THIC1_ARATH Acetyl-CoA acetyltransferase, cytosolic 1 ... 149 5e-035
sp|Q9FIK7|THIC2_ARATH Probable acetyl-CoA acetyltransferase, cyt... 146 6e-034
>sp|Q56WD9|THIK2_ARATH 3-ketoacyl-CoA thiolase 2, peroxisomal OS=Arabidopsis
thaliana GN=PED1 PE=1 SV=2
Length = 462
Score = 716 bits (1848), Expect = 1e-205
Identities = 365/462 (79%), Positives = 389/462 (84%), Gaps = 2/462 (0%)
Frame = +3
Query: 75 MEKAINRQKVLLDHLRPXXXXXXXXXXXXXXXX-XXXXXXXXXRTNVFGDDVVIVAAYRT 251
MEKAI RQ+VLL+HLRP RT+++GDDVVIVAA+RT
Sbjct: 1 MEKAIERQRVLLEHLRPSSSSSHNYEASLSASACLAGDSAAYQRTSLYGDDVVIVAAHRT 60
Query: 252 PLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGSQRASECRMAA 431
PLCK+KRG FKDT+ DDLLAPVL+A+IEKTNLNP EVGDIVVGTVLAPGSQRASECRMAA
Sbjct: 61 PLCKSKRGNFKDTYPDDLLAPVLRALIEKTNLNPSEVGDIVVGTVLAPGSQRASECRMAA 120
Query: 432 FYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTANPMAWEGDVN 611
FYAGFPETV VRTVNRQCSSGLQAVADVAA+I+AGFYDIGIGAGLESMT NPMAWEG VN
Sbjct: 121 FYAGFPETVAVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTTNPMAWEGSVN 180
Query: 612 PKVKIFEQAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXXXGRFKDEIIP 791
P VK F QAQNCLLPMGVTSENVA RFGVSRQEQDQAAVDSHRK G+FKDEIIP
Sbjct: 181 PAVKKFAQAQNCLLPMGVTSENVAQRFGVSRQEQDQAAVDSHRKAAAATAAGKFKDEIIP 240
Query: 792 VATKIVDPKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVFKKDGTTTAGNSSQVSDGAGA 968
V TK+VDPK+GDEKP+T+SVDDGIR TTL+ L KLKPVFKKDGTTTAGNSSQVSDGAGA
Sbjct: 241 VKTKLVDPKTGDEKPITVSVDDGIRPTTTLASLGKLKPVFKKDGTTTAGNSSQVSDGAGA 300
Query: 969 VLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXLELDDIDLFEI 1148
VLLMKRSVA QKG+P+LGVFR+F AVGVDPAIM LELDDIDLFEI
Sbjct: 301 VLLMKRSVAMQKGLPVLGVFRTFAAVGVDPAIMGIGPAVAIPAAVKAAGLELDDIDLFEI 360
Query: 1149 NEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRYG 1328
NEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCR+G
Sbjct: 361 NEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRFG 420
Query: 1329 VISMCIGTGMGAAAVFERGDCTDELCNARKVESLNFLSKDAR 1454
V+SMCIGTGMGAAAVFERGD DEL NARKVE+ LSKDAR
Sbjct: 421 VVSMCIGTGMGAAAVFERGDGVDELRNARKVEAQGLLSKDAR 462
>sp|Q8LF48|THIK1_ARATH 3-ketoacyl-CoA thiolase 1, peroxisomal OS=Arabidopsis
thaliana GN=KAT1 PE=1 SV=2
Length = 443
Score = 659 bits (1699), Expect = 2e-188
Identities = 333/444 (75%), Positives = 364/444 (81%), Gaps = 8/444 (1%)
Frame = +3
Query: 93 RQKVLLDHLRPXXXXXXXXXXXXXXXXXXXXXXXXXRTNVFGDDVVIVAAYRTPLCKAKR 272
RQ++LL HL+P +GDDVVIVAA RT LCKAKR
Sbjct: 7 RQRILLRHLQPSSSSDASLSASACLSKDSAAYQ-------YGDDVVIVAAQRTALCKAKR 59
Query: 273 GGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGSQRASECRMAAFYAGFPE 452
G FKDT D+LLA VL+A+IEKTN+NP EVGDIVVGTVL PGSQRASECRMAAFYAGFPE
Sbjct: 60 GSFKDTFPDELLASVLRALIEKTNVNPSEVGDIVVGTVLGPGSQRASECRMAAFYAGFPE 119
Query: 453 TVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTANPMAWEGDVNPKVKIFE 632
TVP+RTVNRQCSSGLQAVADVAA+I+AGFYDIGIGAGLESMT NP W+G VNP VK FE
Sbjct: 120 TVPIRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTTNPRGWKGSVNPNVKKFE 179
Query: 633 QAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXXXGRFKDEIIPVATKIVD 812
QA NCLLPMG+TSENVAHRF VSR+EQDQAAVDSHRK G+FKDEI PV TKIVD
Sbjct: 180 QAHNCLLPMGITSENVAHRFNVSREEQDQAAVDSHRKAASATASGKFKDEITPVKTKIVD 239
Query: 813 PKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVFKKDGTTTAGNSSQVSDGAGAVLLMKRS 989
PK+GDEKP+T+SVDDGIR NTTLS LAKLKPVFK+DGTTTAGNSSQ+SDGAGAVLLM+R+
Sbjct: 240 PKTGDEKPITVSVDDGIRPNTTLSGLAKLKPVFKEDGTTTAGNSSQLSDGAGAVLLMRRN 299
Query: 990 VADQKGIPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXLELDDIDLFEINEAFASQ 1169
VA QKG+PILGVFR+F AVGVDPAIM LEL+D+DLFEINEAFASQ
Sbjct: 300 VAMQKGLPILGVFRTFSAVGVDPAIMGVGPAVAIPAAVKAAGLELNDVDLFEINEAFASQ 359
Query: 1170 FVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRYGVISMCIG 1349
FVYCRNKLGLD EKINVNGGA+AIGHPLGATGARCVATLLHEMKRRGKDCR+GV+SMCIG
Sbjct: 360 FVYCRNKLGLDAEKINVNGGAIAIGHPLGATGARCVATLLHEMKRRGKDCRFGVVSMCIG 419
Query: 1350 TGMGAAAVFERGDCTDELCNARKV 1421
+GMGAAAVFERG DELC+ RKV
Sbjct: 420 SGMGAAAVFERGGGVDELCDVRKV 443
>sp|Q570C8|THIK5_ARATH 3-ketoacyl-CoA thiolase 5, peroxisomal OS=Arabidopsis
thaliana GN=KAT5 PE=2 SV=2
Length = 457
Score = 583 bits (1502), Expect = 1e-165
Identities = 295/450 (65%), Positives = 352/450 (78%), Gaps = 3/450 (0%)
Frame = +3
Query: 75 MEKAINRQKVLLDHLRPXXXXXXXXXXXXXXXXXXXXXXXXXRTNVFGDDVVIVAAYRTP 254
ME+A+ RQK+LL HL P FGDD+VIVAAYRT
Sbjct: 1 MERAMERQKILLRHLNPVSSSNSSLKHEPSLLSPVNCVSEVSPMAAFGDDIVIVAAYRTA 60
Query: 255 LCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGSQRASECRMAAF 434
+CKA+RGGFKDT DDLLA VLKAV+E+T+L+P EVGDIVVGTV+APGSQRA ECR+AA+
Sbjct: 61 ICKARRGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAY 120
Query: 435 YAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTANPMAWEG--DV 608
+AGFP++VPVRTVNRQCSSGLQAVADVAASIRAG+YDIGIGAG+ESM+ + + G
Sbjct: 121 FAGFPDSVPVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMSTDHIPGGGFHGS 180
Query: 609 NPKVKIFEQAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXXXGRFKDEII 788
NP+ + F +A++CLLPMG+TSENVA RFGV+R+EQD AAV+SH++ G+ KDEII
Sbjct: 181 NPRAQDFPKARDCLLPMGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEII 240
Query: 789 PVATKIVDPKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVFKKDGTTTAGNSSQVSDGAG 965
PVATKIVDP++ EK + +SVDDG+R N+ ++DLAKLK VFK++G+TTAGN+SQ+SDGAG
Sbjct: 241 PVATKIVDPETKAEKAIVVSVDDGVRPNSNMADLAKLKTVFKQNGSTTAGNASQISDGAG 300
Query: 966 AVLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXLELDDIDLFE 1145
AVLLMKRS+A +KG+PILGVFRSF GV+P++M L + DIDLFE
Sbjct: 301 AVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFE 360
Query: 1146 INEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRY 1325
INEAFASQ+VY KL LD EK+NVNGGA+AIGHPLGATGARCVATLLHEMKRRGKDCR+
Sbjct: 361 INEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKDCRF 420
Query: 1326 GVISMCIGTGMGAAAVFERGDCTDELCNAR 1415
GVISMCIGTGMGAAAVFERGD D L NAR
Sbjct: 421 GVISMCIGTGMGAAAVFERGDSVDNLSNAR 450
>sp|Q921H8|THIKA_MOUSE 3-ketoacyl-CoA thiolase A, peroxisomal OS=Mus musculus
GN=Acaa1a PE=2 SV=1
Length = 424
Score = 416 bits (1067), Expect = 4e-115
Identities = 218/387 (56%), Positives = 281/387 (72%), Gaps = 4/387 (1%)
Frame = +3
Query: 222 DVVIVAAYRTPLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGS 401
DVV+V RTP+ +A RGGFK+T D+LL+ VL AV++ L P+++GDI VG VL PG+
Sbjct: 37 DVVVVHGRRTPIGRASRGGFKNTTPDELLSAVLTAVLQDVRLKPEQLGDISVGNVLEPGA 96
Query: 402 QRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTA 581
A R+A F +G PETVP+ TVNRQCSSGLQAVA++A IR G YDIG+ G+ESM+
Sbjct: 97 -GAVMARIAQFLSGIPETVPLSTVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSL 155
Query: 582 NPMAWEGDVNPKVKIFEQAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXX 761
+ M G+++ ++ E+A++CL PMG+TSENVA RFG+SRQ+QD A+ S +K
Sbjct: 156 SGMGNPGNISSRLLESEKARDCLTPMGMTSENVAERFGISRQKQDDFALASQQKAASAQS 215
Query: 762 XGRFKDEIIPVATKIVDPKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVFKKDGTTTAGN 938
G F+ EI+PV T ++D K GD+K +T+S D+G+R +TT+ LAKLKP FK G+TTAGN
Sbjct: 216 RGCFRAEIVPVTTTVLDDK-GDKKTITVSQDEGVRPSTTMQGLAKLKPAFKDGGSTTAGN 274
Query: 939 SSQVSDGAGAVLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXL 1118
SSQVSDGA AVLL +RS A++ G+PILGV RS+ VGV P +M L
Sbjct: 275 SSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDVMGIGPAYAIPAALQKAGL 334
Query: 1119 ELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEM 1298
++DID+FEINEAFASQ VYC KLG+ EK+N GGA+A+GHPLG TGAR V TLL+E+
Sbjct: 335 TVNDIDIFEINEAFASQAVYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNEL 394
Query: 1299 KRRGKDCRYGVISMCIGTGMGAAAVFE 1379
KRRG+ YGV+SMCIGTGMGAAAVFE
Sbjct: 395 KRRGRRA-YGVVSMCIGTGMGAAAVFE 420
>sp|P07871|THIKB_RAT 3-ketoacyl-CoA thiolase B, peroxisomal OS=Rattus norvegicus
GN=Acaa1b PE=2 SV=2
Length = 424
Score = 413 bits (1061), Expect = 2e-114
Identities = 218/387 (56%), Positives = 279/387 (72%), Gaps = 4/387 (1%)
Frame = +3
Query: 222 DVVIVAAYRTPLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGS 401
DVV+V RTP+ +A RGGFKDT D+LL+ VL AV++ L P+ +GDI VG VL PG+
Sbjct: 37 DVVVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLQPGA 96
Query: 402 QRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTA 581
A+ R+A F +G PETVP+ VNRQCSSGLQAVA++A IR G YDIG+ G+ESMT
Sbjct: 97 -GAAMARIAQFLSGIPETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMTL 155
Query: 582 NPMAWEGDVNPKVKIFEQAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXX 761
+ G+++ ++ E+A++CL+PMG+TSENVA RFG+SRQ+QD A+ S +K
Sbjct: 156 SERGNPGNISSRLLENEKARDCLIPMGITSENVAERFGISRQKQDAFALASQQKAASAQS 215
Query: 762 XGRFKDEIIPVATKIVDPKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVFKKDGTTTAGN 938
G F+ EI+PV T ++D K GD K +T+S D+G+R +TT+ LAKLKP FK G+TTAGN
Sbjct: 216 KGCFRAEIVPVTTTVLDDK-GDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGGSTTAGN 274
Query: 939 SSQVSDGAGAVLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXL 1118
SSQVSDGA AVLL +RS A++ G+PILGV RS+ VGV P IM L
Sbjct: 275 SSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGL 334
Query: 1119 ELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEM 1298
++DID+FEINEAFASQ +YC KLG+ EK+N GGA+A+GHPLG TGAR V TLL+E+
Sbjct: 335 TVNDIDIFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNEL 394
Query: 1299 KRRGKDCRYGVISMCIGTGMGAAAVFE 1379
KRRG+ YGV+SMCIGTGMGAAAVFE
Sbjct: 395 KRRGRRA-YGVVSMCIGTGMGAAAVFE 420
>sp|Q8VCH0|THIKB_MOUSE 3-ketoacyl-CoA thiolase B, peroxisomal OS=Mus musculus
GN=Acaa1b PE=2 SV=1
Length = 424
Score = 413 bits (1059), Expect = 3e-114
Identities = 218/387 (56%), Positives = 279/387 (72%), Gaps = 4/387 (1%)
Frame = +3
Query: 222 DVVIVAAYRTPLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGS 401
DVV+V RTP+ +A RG FKDT D+LL+ VL AV++ L P+++GDI VG VL PG+
Sbjct: 37 DVVVVHGRRTPIGRASRGCFKDTTPDELLSAVLTAVLQDVKLKPEQLGDISVGNVLQPGA 96
Query: 402 QRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTA 581
A R+A F +G PETVP+ TVNRQCSSGLQAVA++A IR G YDIG+ G+ESMT
Sbjct: 97 -GAIMARIAQFLSGIPETVPLSTVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMTL 155
Query: 582 NPMAWEGDVNPKVKIFEQAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXX 761
+ G+++ ++ E+A++CL+PMG+TSENVA RFGVSRQ+QD A+ S +K
Sbjct: 156 SQRGNHGNISSRLLENEKARDCLIPMGITSENVAERFGVSRQKQDAFALASQQKAASAQS 215
Query: 762 XGRFKDEIIPVATKIVDPKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVFKKDGTTTAGN 938
G F EI+PV T +++ K GD+K +T+S D+G+R +TT+ LAKLKP FK G+TTAGN
Sbjct: 216 RGCFHAEIVPVTTTVLNDK-GDKKTITVSQDEGVRPSTTMQGLAKLKPAFKDGGSTTAGN 274
Query: 939 SSQVSDGAGAVLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXL 1118
SSQVSDGA AVLL +RS A++ G+PILGV RS+ VGV P +M L
Sbjct: 275 SSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDVMGIGPAYAIPAALQKAGL 334
Query: 1119 ELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEM 1298
++DID+FEINEAFASQ VYC KLG+ EK+N GGA+A+GHPLG TGAR V TLL+E+
Sbjct: 335 TVNDIDIFEINEAFASQAVYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNEL 394
Query: 1299 KRRGKDCRYGVISMCIGTGMGAAAVFE 1379
KRRG+ YGV+SMCIGTGMGAAAVFE
Sbjct: 395 KRRGRRA-YGVVSMCIGTGMGAAAVFE 420
>sp|P09110|THIK_HUMAN 3-ketoacyl-CoA thiolase, peroxisomal OS=Homo sapiens
GN=ACAA1 PE=1 SV=2
Length = 424
Score = 411 bits (1054), Expect = 1e-113
Identities = 216/387 (55%), Positives = 276/387 (71%), Gaps = 4/387 (1%)
Frame = +3
Query: 222 DVVIVAAYRTPLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGS 401
DVV+V RT +C+A RGGFKDT D+LL+ V+ AV++ NL P+++GDI VG VL PG+
Sbjct: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96
Query: 402 QRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTA 581
A R+A F + PETVP+ TVNRQCSSGLQAVA +A IR G YDIG+ G+ESM+
Sbjct: 97 -GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSL 155
Query: 582 NPMAWEGDVNPKVKIFEQAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXX 761
G++ ++ E+A++CL+PMG+TSENVA RFG+SR++QD A+ S +K
Sbjct: 156 ADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQS 215
Query: 762 XGRFKDEIIPVATKIVDPKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVFKKDGTTTAGN 938
G F+ EI+PV T + D K G ++ +T++ D+GIR +TT+ LAKLKP FKKDG+TTAGN
Sbjct: 216 KGCFQAEIVPVTTTVHDDK-GTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGN 274
Query: 939 SSQVSDGAGAVLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXL 1118
SSQVSDGA A+LL +RS A++ G+PILGV RS+ VGV P IM L
Sbjct: 275 SSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGL 334
Query: 1119 ELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEM 1298
+ D+D+FEINEAFASQ YC KL L PEK+N GGA+A+GHPLG TGAR V TLL+E+
Sbjct: 335 TVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNEL 394
Query: 1299 KRRGKDCRYGVISMCIGTGMGAAAVFE 1379
KRRGK YGV+SMCIGTGMGAAAVFE
Sbjct: 395 KRRGKRA-YGVVSMCIGTGMGAAAVFE 420
>sp|P21775|THIKA_RAT 3-ketoacyl-CoA thiolase A, peroxisomal OS=Rattus norvegicus
GN=Acaa1a PE=2 SV=2
Length = 424
Score = 409 bits (1051), Expect = 3e-113
Identities = 216/387 (55%), Positives = 278/387 (71%), Gaps = 4/387 (1%)
Frame = +3
Query: 222 DVVIVAAYRTPLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGS 401
DVV+V RTP+ +A RGGFKDT D+LL+ VL AV++ L P+ +GDI VG VL PG+
Sbjct: 37 DVVVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGA 96
Query: 402 QRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTA 581
A R+A F +G PETVP+ VNRQCSSGLQAVA++A IR G YDIG+ G+ESM+
Sbjct: 97 -GAVMARIAQFLSGIPETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSL 155
Query: 582 NPMAWEGDVNPKVKIFEQAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXX 761
+ G+++ ++ ++A++CL+PMG+TSENVA RFG+SRQ+QD A+ S +K
Sbjct: 156 SNRGNPGNISSRLLESDKARDCLIPMGITSENVAERFGISRQKQDAFALASQQKAASAQS 215
Query: 762 XGRFKDEIIPVATKIVDPKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVFKKDGTTTAGN 938
G F+ EI+PV T ++D K GD K +T+S D+G+R +TT+ LAKLKP FK G+TTAGN
Sbjct: 216 KGCFRAEIVPVTTTVLDDK-GDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGGSTTAGN 274
Query: 939 SSQVSDGAGAVLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXL 1118
SSQVSDGA AVLL +RS A++ G+PILGV RS+ VGV P IM L
Sbjct: 275 SSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGL 334
Query: 1119 ELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEM 1298
++DID+FEINEAFASQ +YC KLG+ EK+N GGA+A+GHPLG TGAR V TLL+E+
Sbjct: 335 TVNDIDIFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNEL 394
Query: 1299 KRRGKDCRYGVISMCIGTGMGAAAVFE 1379
KRRG+ YGV+SMCIGTGMGAAAVFE
Sbjct: 395 KRRGRRA-YGVVSMCIGTGMGAAAVFE 420
>sp|Q05493|THIK_YARLI 3-ketoacyl-CoA thiolase, peroxisomal OS=Yarrowia
lipolytica GN=POT1 PE=3 SV=1
Length = 414
Score = 353 bits (905), Expect = 2e-096
Identities = 199/389 (51%), Positives = 255/389 (65%), Gaps = 10/389 (2%)
Frame = +3
Query: 219 DDVVIVAAYRTPLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPG 398
DDVVI AAYRT K +G FKDT + +LLA +L+ +++++ ++PK +GD+V G VLA G
Sbjct: 28 DDVVITAAYRTAHTKGGKGLFKDTSSSELLASLLEGLVKESKIDPKLIGDVVCGNVLAAG 87
Query: 399 SQRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMT 578
+ A+E R A AG PETVP +NRQCSSGL AV DVA IRAG DIGIG G+ESM
Sbjct: 88 A-GATEHRAACLVAGIPETVPFVALNRQCSSGLMAVNDVANKIRAGQIDIGIGCGVESM- 145
Query: 579 ANPMAWEGDVNP---KVKIFEQAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVDSHRKXX 749
+ V P K + E+A+ CL+PMG+TSENVA ++ VSR+ QD A S+ K
Sbjct: 146 -SNQYGPNSVTPFSNKFQNNEEAKKCLIPMGITSENVAAKYNVSRKAQDAFAAKSYEKAA 204
Query: 750 XXXXXGRFKDEIIPVATKIVDPKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVFKKDGTT 926
G+F EI+P+ T ++D +EK VT++ DDGIR T L KLKP F +GTT
Sbjct: 205 AAQAAGKFDQEILPIKTTVLD-DDDNEKEVTVNKDDGIRPGVTAEKLGKLKPAFSAEGTT 263
Query: 927 TAGNSSQVSDGAGAVLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXX 1106
AGN+SQ+SDGAGAVLLM+RSVA++ G PIL F VGV P +M
Sbjct: 264 HAGNASQISDGAGAVLLMRRSVAEKLGQPILAKFVHCKTVGVPPELMGIGPAYAIPAVLE 323
Query: 1107 XXXLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATL 1286
L ++D+D+FEINEAFASQ ++ G+D K+N GGA+AIGHPLGATGAR ATL
Sbjct: 324 DLGLTVNDVDVFEINEAFASQALFSIQHCGIDESKVNPRGGAIAIGHPLGATGARQFATL 383
Query: 1287 LHEMKRRGKDCRYGVISMCIGTGMGAAAV 1373
L E+K GK + GV SMCIGTGMGAA++
Sbjct: 384 LSELKESGK--KVGVTSMCIGTGMGAASL 410
>sp|O32177|FADA_BACSU 3-ketoacyl-CoA thiolase OS=Bacillus subtilis GN=fadA PE=2
SV=1
Length = 391
Score = 309 bits (789), Expect = 7e-083
Identities = 176/391 (45%), Positives = 230/391 (58%), Gaps = 9/391 (2%)
Frame = +3
Query: 222 DVVIVAAYRTPLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGS 401
+ VIV+ RTP+ KAK+G DDL A +K +++ + D+++G
Sbjct: 3 EAVIVSGARTPVGKAKKGSLATVRPDDLGAICVKETLKRAGGYEGNIDDLIIGCATPEAE 62
Query: 402 QRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTA 581
Q + R AG P TVP TVNR CSSGLQ++A A I G YD I G ESM+
Sbjct: 63 QGLNMARNIGALAGLPYTVPAITVNRYCSSGLQSIAYAAEKIMLGAYDTAIAGGAESMSQ 122
Query: 582 NPMAWEGDV-NPKVKIFEQAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXX 758
PM G V P + + E+A + MG T+E VA ++GVSR++QD AV SH+
Sbjct: 123 VPMM--GHVTRPNLALAEKAPEYYMSMGHTAEQVAKKYGVSREDQDAFAVRSHQNAAKAL 180
Query: 759 XXGRFKDEIIPV---ATKIVDPKSGDEKPVTISVDDGIRNTTLSD-LAKLKPVFKKDGTT 926
G+FKDEI+PV T+I + EK S D+G+R T +D L+ L+P F DGT
Sbjct: 181 AEGKFKDEIVPVEVTVTEIGEDHKPMEKQFVFSQDEGVRPQTTADILSTLRPAFSVDGTV 240
Query: 927 TAGNSSQVSDGAGAVLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXX 1106
TAGNSSQ SDGA AV+LM R AD G+ L FRSF GV P +M
Sbjct: 241 TAGNSSQTSDGAAAVMLMDREKADALGLAPLVKFRSFAVGGVPPEVMGIGPVEAIPRALK 300
Query: 1107 XXXLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATL 1286
L+L DI LFE+NEAFASQ + +LG+D EK+NVNGGA+A+GHPLG TG + +L
Sbjct: 301 LAGLQLQDIGLFELNEAFASQAIQVIRELGIDEEKVNVNGGAIALGHPLGCTGTKLTLSL 360
Query: 1287 LHEMKRRGKDCRYGVISMCIGTGMGAAAVFE 1379
+HEMKRR + ++GV++MCIG GMGAA VFE
Sbjct: 361 IHEMKRRNE--QFGVVTMCIGGGMGAAGVFE 389
>sp|P76461|ATOB_ECOLI Acetyl-CoA acetyltransferase OS=Escherichia coli (strain
K12) GN=atoB PE=3 SV=1
Length = 394
Score = 242 bits (616), Expect = 8e-063
Identities = 153/398 (38%), Positives = 222/398 (55%), Gaps = 23/398 (5%)
Frame = +3
Query: 228 VIVAAYRTPLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGSQR 407
VIV+A RT + + G T A DL A V+KA IE+ ++ + V ++++G VL G +
Sbjct: 5 VIVSAVRTAI-GSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAGLGQ 63
Query: 408 ASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTANP 587
+ R A +G ETV TVN+ C SGL++VA A +I+AG + G+E+M+ P
Sbjct: 64 -NPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSLAP 122
Query: 588 MAWEGDVNPKVKIFE-QAQNCLL-----------PMGVTSENVAHRFGVSRQEQDQAAVD 731
+ ++ + Q + +L MG+T+ENVA +G++R+ QD+ A+
Sbjct: 123 YLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELALH 182
Query: 732 SHRKXXXXXXXGRFKDEIIPVATKIVDPKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVF 908
S RK G F EI+PV +V K K S D+ + N+T L L+P F
Sbjct: 183 SQRKAAAAIESGAFTAEIVPV--NVVTRK----KTFVFSQDEFPKANSTAEALGALRPAF 236
Query: 909 KKDGTTTAGNSSQVSDGAGAVLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXX 1088
K GT TAGN+S ++DGA A+++M+ S A G+ L +S+ + GV PA+M
Sbjct: 237 DKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPA 296
Query: 1089 XXXXXXXXXLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGA 1268
L+L DIDL E NEAFA+QF+ LG D EK+NVNGGA+A+GHP+GA+GA
Sbjct: 297 TQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASGA 356
Query: 1269 RCVATLLHEMKRRGKDCRYGVISMCIGTGMGAAAVFER 1382
R + TLLH M+ R K G+ ++CIG G G A V ER
Sbjct: 357 RILVTLLHAMQARDK--TLGLATLCIGGGQGIAMVIER 392
>sp|Q9BWD1|THIC_HUMAN Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens
GN=ACAT2 PE=1 SV=2
Length = 397
Score = 231 bits (587), Expect = 2e-059
Identities = 152/410 (37%), Positives = 227/410 (55%), Gaps = 33/410 (8%)
Frame = +3
Query: 207 NVFGDDVVIVAAYRTPLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTV 386
N D VVIV+A RT + + G DL + V+K V+++ + P++V +++ G V
Sbjct: 2 NAGSDPVVIVSAART-IIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV 60
Query: 387 LAPGSQRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGL 566
LA G + + R A+ AG P +VP + C SGL+AV SI G I + G+
Sbjct: 61 LAAGCGQ-NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGM 119
Query: 567 ESMTANP-MAWEGDVNPKVKIFEQA--------------QNCLLPMGVTSENVAHRFGVS 701
E+M+ P +A+ + VKI E NC MG+T+ENVA ++ VS
Sbjct: 120 ENMSKAPHLAY---LRTGVKIGEMPLTDSILCDGLTDAFHNC--HMGITAENVAKKWQVS 174
Query: 702 RQEQDQAAVDSHRKXXXXXXXGRFKDEIIPVATKIVDPKSGDEKPVTISVDDGIRN-TTL 878
R++QD+ AV S + G F EI+PV +V + G + + D+ R+ + +
Sbjct: 175 REDQDKVAVLSQNRTENAQKAGHFDKEIVPV---LVSTRKG---LIEVKTDEFPRHGSNI 228
Query: 879 SDLAKLKPVFKKD--GTTTAGNSSQVSDGAGAVLLMKRSVADQKGIPILGVFRSFVAVGV 1052
++KLKP F D GT T N+S ++DGA AV+LMK+S AD++G+ L S+ VGV
Sbjct: 229 EAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGV 288
Query: 1053 DPAIMXXXXXXXXXXXXXXXXLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGA 1232
+P+IM L+D+D+FEINEAFA+ +LGL+PEK+N+ GGA
Sbjct: 289 EPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGA 348
Query: 1233 MAIGHPLGATGARCVATLLHEMKRRGKDCRYGVISMCIGTGMGAAAVFER 1382
+A+GHPLGA+G R + TLLH ++R G+ GV ++CIG GMG A +R
Sbjct: 349 IALGHPLGASGCRILVTLLHTLERMGRS--RGVAALCIGGGMGIAMCVQR 396
>sp|P27796|THIK_YEAST 3-ketoacyl-CoA thiolase, peroxisomal OS=Saccharomyces
cerevisiae GN=FOX3 PE=1 SV=1
Length = 417
Score = 227 bits (577), Expect = 3e-058
Identities = 121/249 (48%), Positives = 161/249 (64%), Gaps = 13/249 (5%)
Frame = +3
Query: 633 QAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXXXGRFKDEIIPVATKIVD 812
+A+ CL+PMG+T+ENVA F +SR++QD+ A +S++K G F+DEI+P+
Sbjct: 178 EAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGS 237
Query: 813 PKSGDEKPVTISVDDGIRNTTLSDLAKLKPVFKKD-GTTTAGNSSQVSDGAGAVLLMKRS 989
DE P N T L+ ++P F KD GTTTAGN+SQVSDG VLL +RS
Sbjct: 238 ICQSDEGPRP--------NVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRS 289
Query: 990 VADQKGIPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXLELDDIDLFEINEAFASQ 1169
VA+Q +P+LG + F VGV P IM L++ DID+FEINEAFA+Q
Sbjct: 290 VANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQ 349
Query: 1170 FVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRYGVISMCIG 1349
+YC +KLG+D K+N GGA+A+GHPLG TGAR VAT+L E+K+ + GV+SMCIG
Sbjct: 350 ALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVATILRELKKD----QIGVVSMCIG 405
Query: 1350 TGMGAAAVF 1376
TGMGAAA+F
Sbjct: 406 TGMGAAAIF 414
>sp|Q8BWT1|THIM_MOUSE 3-ketoacyl-CoA thiolase, mitochondrial OS=Mus musculus
GN=Acaa2 PE=1 SV=2
Length = 397
Score = 223 bits (567), Expect = 4e-057
Identities = 142/397 (35%), Positives = 203/397 (51%), Gaps = 21/397 (5%)
Frame = +3
Query: 225 VVIVAAYRTPLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGSQ 404
V IVAA RTP A G KD A DL +A + + P+ + ++VG V+ S
Sbjct: 7 VFIVAAKRTPF-GAYGGLLKDFSATDLTEFAARAALSAGKVPPETIDSVIVGNVMQSSSD 65
Query: 405 RASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTAN 584
A R G P T+NR C SG Q++ I + ++ + G ESM+ +
Sbjct: 66 AAYLARHVGLRVGVPTETGALTLNRLCGSGFQSIVSGCQEICSKDAEVVLCGGTESMSQS 125
Query: 585 PMAWEG---------DVNPKVKIFE--QAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVD 731
P D+ + ++ Q+ LPMG+T+EN+A ++ +SR++ D+ A+
Sbjct: 126 PYCVRNVRFGTKFGLDLKLEDTLWAGLTDQHVKLPMGMTAENLAAKYNISREDCDRYALQ 185
Query: 732 SHRKXXXXXXXGRFKDEIIPVATKIVDPKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVF 908
S ++ G F +E+ P+ K K G + T+ VD+ R TTL L KL VF
Sbjct: 186 SQQRWKAANEAGYFNEEMAPIEVK---TKKGKQ---TMQVDEHARPQTTLEQLQKLPSVF 239
Query: 909 KKDGTTTAGNSSQVSDGAGAVLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXX 1088
KKDGT TAGN+S VSDGAGAV++ + L + G DP IM
Sbjct: 240 KKDGTVTAGNASGVSDGAGAVIIASEDAVKKHNFTPLARVVGYFVSGCDPTIMGIGPVPA 299
Query: 1089 XXXXXXXXXLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGA 1268
L L D+DL ++NEAFA QF+ + L LDP K NV+GGA+A+GHPLG +G+
Sbjct: 300 INGALKKAGLSLKDMDLIDVNEAFAPQFLSVQKALDLDPSKTNVSGGAIALGHPLGGSGS 359
Query: 1269 RCVATLLHEMKRRGKDCRYGVISMCIGTGMGAAAVFE 1379
R A L+HE++RRG +Y V S CIG G G A + +
Sbjct: 360 RITAHLVHELRRRGG--KYAVGSACIGGGQGIALIIQ 394
>sp|P13437|THIM_RAT 3-ketoacyl-CoA thiolase, mitochondrial OS=Rattus norvegicus
GN=Acaa2 PE=1 SV=1
Length = 397
Score = 221 bits (562), Expect = 1e-056
Identities = 139/397 (35%), Positives = 204/397 (51%), Gaps = 21/397 (5%)
Frame = +3
Query: 225 VVIVAAYRTPLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGSQ 404
V IVAA RTP A G KD A DL +A + + P+ + ++VG V+ S
Sbjct: 7 VFIVAAKRTPF-GAYGGLLKDFTATDLTEFAARAALSAGKVPPETIDSVIVGNVMQSSSD 65
Query: 405 RASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTAN 584
A R G P T+NR C SG Q++ I + ++ + G ESM+ +
Sbjct: 66 AAYLARHVGLRVGVPTETGALTLNRLCGSGFQSIVSGCQEICSKDAEVVLCGGTESMSQS 125
Query: 585 PMAWEG---------DVNPKVKIFE--QAQNCLLPMGVTSENVAHRFGVSRQEQDQAAVD 731
P + D+ + ++ Q+ LPMG+T+EN+A ++ +SR++ D+ A+
Sbjct: 126 PYSVRNVRFGTKFGLDLKLEDTLWAGLTDQHVKLPMGMTAENLAAKYNISREDCDRYALQ 185
Query: 732 SHRKXXXXXXXGRFKDEIIPVATKIVDPKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVF 908
S ++ G F +E+ P+ K K G + T+ VD+ R TTL L L PVF
Sbjct: 186 SQQRWKAANEAGYFNEEMAPIEVK---TKKGKQ---TMQVDEHARPQTTLEQLQNLPPVF 239
Query: 909 KKDGTTTAGNSSQVSDGAGAVLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXX 1088
KK+GT TAGN+S +SDGAG V++ + L + G DPAIM
Sbjct: 240 KKEGTVTAGNASGMSDGAGVVIIASEDAVKKHNFTPLARVVGYFVSGCDPAIMGIGPVPA 299
Query: 1089 XXXXXXXXXLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGA 1268
L L D+DL ++NEAFA QF+ + L LDP K NV+GGA+A+GHPLG +G+
Sbjct: 300 ITGALKKAGLSLKDMDLIDVNEAFAPQFLAVQKSLDLDPSKTNVSGGAIALGHPLGGSGS 359
Query: 1269 RCVATLLHEMKRRGKDCRYGVISMCIGTGMGAAAVFE 1379
R A L+HE++RRG +Y V S CIG G G + + +
Sbjct: 360 RITAHLVHELRRRGG--KYAVGSACIGGGQGISLIIQ 394
>sp|Q3T0R7|THIM_BOVIN 3-ketoacyl-CoA thiolase, mitochondrial OS=Bos taurus
GN=ACAA2 PE=2 SV=1
Length = 397
Score = 220 bits (559), Expect = 3e-056
Identities = 140/397 (35%), Positives = 200/397 (50%), Gaps = 21/397 (5%)
Frame = +3
Query: 225 VVIVAAYRTPLCKAKRGGFKDTHADDLLAPVLKAVIEKTNLNPKEVGDIVVGTVLAPGSQ 404
V IVAA RTP A G KD D+ +A + ++P+ V +VVG V+ S
Sbjct: 7 VFIVAAKRTPF-GAYGGLLKDFTPTDMAEFAARAALSAGRVSPETVDSVVVGNVMQSSSD 65
Query: 405 RASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAASIRAGFYDIGIGAGLESMTAN 584
R G P+ P T+NR C SG Q++ I + ++ + G ESM+
Sbjct: 66 AIYLARHVGLRVGIPKETPAITINRLCGSGFQSIVSGCQEICSRDSEVVLCGGTESMSQA 125
Query: 585 P-----MAWEGDVNPKVKIFEQAQNCL------LPMGVTSENVAHRFGVSRQEQDQAAVD 731
P + + + ++K+ + L +PM +T+EN+A + +SR++ D+ A+
Sbjct: 126 PYCVRNIRFGTKLGSELKLEDTLWTGLTDTHVQMPMAITAENLAVKHQISREDCDRYALQ 185
Query: 732 SHRKXXXXXXXGRFKDEIIPVATKIVDPKSGDEKPVTISVDDGIR-NTTLSDLAKLKPVF 908
S ++ G F +E+ PV K K T+ VD+ R TT+ L KL PVF
Sbjct: 186 SQQRWKTANDAGYFDNEMAPVEVKTRKGKQ------TMQVDEHPRPQTTMEQLNKLPPVF 239
Query: 909 KKDGTTTAGNSSQVSDGAGAVLLMKRSVADQKGIPILGVFRSFVAVGVDPAIMXXXXXXX 1088
KK+GT TAGN+S VSDGAGAV++ + L + G DP IM
Sbjct: 240 KKEGTVTAGNASGVSDGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPTIMGIGPVPA 299
Query: 1089 XXXXXXXXXLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGA 1268
L L D+DL E+NEAFA Q++ L LDP K NVNGGA+A+GHPL +G+
Sbjct: 300 ISGALKKTGLSLKDMDLVEVNEAFAPQYLAVEKSLNLDPSKTNVNGGAIALGHPLAGSGS 359
Query: 1269 RCVATLLHEMKRRGKDCRYGVISMCIGTGMGAAAVFE 1379
R A L+HE++RRG +Y V S CIG G G A + E
Sbjct: 360 RITAHLVHELRRRGG--KYAVGSACIGGGQGIAVIIE 394
>sp|P14611|THIL_RALEH Acetyl-CoA acetyltransferase OS=Ralstonia eutropha (strain
ATCC 17699 / H16 / DSM 428 / Stanier 337) GN=phbA PE=3 SV=1
Length = 393
Score = 198 bits (501), Expect = 2e-049
Identities = 105/243 (43%), Positives = 146/243 (60%), Gaps = 8/243 (3%)
Frame = +3
Query: 657 MGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXXXGRFKDEIIPVATKIVDPKSGDEKP 836
MG+T+ENVA +G++R+ QD+ AV S K G+F +EI+PV ++ + GD P
Sbjct: 157 MGITAENVAKEYGITREAQDEFAVGSQNKAEAAQKAGKFDEEIVPV---LIPQRKGD--P 211
Query: 837 VTISVDDGIR-NTTLSDLAKLKPVFKKDGTTTAGNSSQVSDGAGAVLLMKRSVADQKGIP 1013
V D+ +R TL ++ LKP F K GT TA N+S ++DGA AV++M + A + G+
Sbjct: 212 VAFKTDEFVRQGATLDSMSGLKPAFDKAGTVTAANASGLNDGAAAVVVMSAAKAKELGLT 271
Query: 1014 ILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXLELDDIDLFEINEAFASQFVYCRNKL 1193
L +S+ GVDP +M D+DL EINEAFA+Q + ++
Sbjct: 272 PLATIKSYANAGVDPKVMGMGPVPASKRALSRAEWTPQDLDLMEINEAFAAQALAVHQQM 331
Query: 1194 GLDPEKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRYGVISMCIGTGMGAAAV 1373
G D K+NVNGGA+AIGHP+GA+G R + TLLHEMKRR D + G+ S+CIG GMG A
Sbjct: 332 GWDTSKVNVNGGAIAIGHPIGASGCRILVTLLHEMKRR--DAKKGLASLCIGGGMGVALA 389
Query: 1374 FER 1382
ER
Sbjct: 390 VER 392
>sp|Q8CAY6|THIC_MOUSE Acetyl-CoA acetyltransferase, cytosolic OS=Mus musculus
GN=Acat2 PE=1 SV=2
Length = 397
Score = 171 bits (431), Expect = 2e-041
Identities = 99/245 (40%), Positives = 146/245 (59%), Gaps = 11/245 (4%)
Frame = +3
Query: 657 MGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXXXGRFKDEIIPVATKIVDPKSGDEKP 836
MG+T+ENVA ++ VSR+ QD+ AV S + G F EI+PV +V + G
Sbjct: 160 MGITAENVAKKWQVSREAQDKVAVLSQNRAEHAQKAGHFDKEIVPV---LVSSRKG---L 213
Query: 837 VTISVDDGIRN-TTLSDLAKLKPVFKKD--GTTTAGNSSQVSDGAGAVLLMKRSVADQKG 1007
+ +D+ R+ + L + KLKP F D GT T N+S ++DGA AV+LMK++ A+++
Sbjct: 214 TEVKIDEFPRHGSNLEAMGKLKPYFLTDGTGTVTPANASGMNDGAAAVVLMKKTEAERRM 273
Query: 1008 IPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXLELDDIDLFEINEAFASQFVYCRN 1187
+ L S+ GV+P++M L+D+DLFEINEAFA+
Sbjct: 274 LKPLARIVSWSQAGVEPSVMGVGPIPAIKQAVAKAGWSLEDVDLFEINEAFAAVSAAIAK 333
Query: 1188 KLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRYGVISMCIGTGMGAA 1367
+LGL+PEK+N++GGA+A+GHPLGA+G R + TLLH ++R G GV ++CIG GMG A
Sbjct: 334 ELGLNPEKVNIDGGAIALGHPLGASGCRILVTLLHTLERVGG--TRGVAALCIGGGMGVA 391
Query: 1368 AVFER 1382
+R
Sbjct: 392 MCVQR 396
>sp|P45855|THL_BACSU Acetyl-CoA acetyltransferase OS=Bacillus subtilis GN=mmgA
PE=2 SV=2
Length = 393
Score = 169 bits (427), Expect = 7e-041
Identities = 96/242 (39%), Positives = 136/242 (56%), Gaps = 8/242 (3%)
Frame = +3
Query: 657 MGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXXXGRFKDEIIPVATKIVDPKSGDEKP 836
M V A + +SR+EQD+ A+ SH + G+F+DEI+PV + K KP
Sbjct: 157 MAVHGNTAAKEYAISRREQDEWALRSHARAAKAADEGKFQDEIVPV--NWIGRKG---KP 211
Query: 837 VTISVDDGI-RNTTLSDLAKLKPVFKKDGTTTAGNSSQVSDGAGAVLLMKRSVADQKGIP 1013
+ D+ I R+T+L LAKL P++ DG+ TAGN+ V+DGAGA +LM A + G
Sbjct: 212 NVVDKDEAIRRDTSLDQLAKLAPIYASDGSITAGNAPGVNDGAGAFVLMSEEKAAELGKR 271
Query: 1014 ILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXLELDDIDLFEINEAFASQFVYCRNKL 1193
L F G+ + L + DIDLFE+NEAFAS + C +
Sbjct: 272 PLATILGFSTTGMPAHELAAAPGFAINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIV 331
Query: 1194 GLDPEKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRYGVISMCIGTGMGAAAV 1373
G D EK+NVNGGA+A+GHP+GA+GAR + TL++E+KRRG GV ++C G G A +
Sbjct: 332 GFDLEKVNVNGGAIALGHPIGASGARILMTLVYELKRRGGG--LGVAAICSGAAQGDAVL 389
Query: 1374 FE 1379
+
Sbjct: 390 VQ 391
>sp|Q5XI22|THIC_RAT Acetyl-CoA acetyltransferase, cytosolic OS=Rattus norvegicus
GN=Acat2 PE=1 SV=1
Length = 397
Score = 168 bits (424), Expect = 1e-040
Identities = 97/245 (39%), Positives = 143/245 (58%), Gaps = 11/245 (4%)
Frame = +3
Query: 657 MGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXXXGRFKDEIIPVATKIVDPKSGDEKP 836
MG+T+ENVA ++ VSR+ QD+ AV S + G F EI+PV S +
Sbjct: 160 MGITAENVAKKWQVSREAQDKVAVVSQNRAEHAQKAGHFDKEIVPVHV------SSRKGL 213
Query: 837 VTISVDDGIRN-TTLSDLAKLKPVFKKD--GTTTAGNSSQVSDGAGAVLLMKRSVADQKG 1007
+ +D+ R+ + L ++KLKP F D GT T N+S ++DGA AV+LMK++ A+ +
Sbjct: 214 TEVKIDEFPRHGSNLEAMSKLKPYFLTDGTGTVTPANASGMNDGAAAVVLMKKTEAESRM 273
Query: 1008 IPILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXLELDDIDLFEINEAFASQFVYCRN 1187
+ L S+ GV+P++M L+D+D+FEINEAFA+
Sbjct: 274 LKPLAQVVSWSQAGVEPSVMGVGPIPAIKQAVAKAGWSLEDVDVFEINEAFAAVSAAIAK 333
Query: 1188 KLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRYGVISMCIGTGMGAA 1367
+LGL PEK+N++GGA+A+GHPLGA+G R + TLLH ++R G GV ++CIG GMG A
Sbjct: 334 ELGLSPEKVNIDGGAIALGHPLGASGCRILVTLLHTLERVGG--TRGVAALCIGGGMGIA 391
Query: 1368 AVFER 1382
+R
Sbjct: 392 MCVQR 396
>sp|Q8S4Y1|THIC1_ARATH Acetyl-CoA acetyltransferase, cytosolic 1 OS=Arabidopsis
thaliana GN=AAT1 PE=2 SV=1
Length = 403
Score = 149 bits (376), Expect = 5e-035
Identities = 90/243 (37%), Positives = 133/243 (54%), Gaps = 9/243 (3%)
Frame = +3
Query: 657 MGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXXXGRFKDEIIPVATKIVDPKSGDEKP 836
MG +E A +F ++R++QD AV S + G F EI+P V+ G +P
Sbjct: 166 MGSCAELCAEKFQITREQQDDYAVQSFERGIAAQEAGAFTWEIVP-----VEVSGGRGRP 220
Query: 837 VTI-SVDDGIRNTTLSDLAKLKPVFKKD-GTTTAGNSSQVSDGAGAVLLMKRSVADQKGI 1010
TI D+G+ + L KL+P FK++ GT TAGN+S +SDGA A++L+ A Q G+
Sbjct: 221 STIVDKDEGLGKFDAAKLRKLRPSFKENGGTVTAGNASSISDGAAALVLVSGEKALQLGL 280
Query: 1011 PILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXLELDDIDLFEINEAFASQFVYCRNK 1190
+L + + +P LE +D +EINEAFA + +
Sbjct: 281 LVLAKIKGYGDAAQEPEFFTTAPALAIPKAIAHAGLESSQVDYYEINEAFAVVALANQKL 340
Query: 1191 LGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRYGVISMCIGTGMGAAA 1370
LG+ PEK+NVNGGA+++GHPLG +GAR + TLL +K+R + +YGV +C G G +A
Sbjct: 341 LGIAPEKVNVNGGAVSLGHPLGCSGARILITLLGILKKR--NGKYGVGGVCNGGGGASAL 398
Query: 1371 VFE 1379
V E
Sbjct: 399 VLE 401
>sp|Q9FIK7|THIC2_ARATH Probable acetyl-CoA acetyltransferase, cytosolic 2
OS=Arabidopsis thaliana GN=At5g47720 PE=2 SV=1
Length = 415
Score = 146 bits (367), Expect = 6e-034
Identities = 86/243 (35%), Positives = 132/243 (54%), Gaps = 9/243 (3%)
Frame = +3
Query: 657 MGVTSENVAHRFGVSRQEQDQAAVDSHRKXXXXXXXGRFKDEIIPVATKIVDPKSGDEKP 836
MGV E A ++ ++R+EQD A+ S + F EI+P V+ +G +P
Sbjct: 168 MGVCGEICADQYRITREEQDAYAIQSFERGIAAQNTQLFAWEIVP-----VEVSTGRGRP 222
Query: 837 -VTISVDDGIRNTTLSDLAKLKPVFKKD-GTTTAGNSSQVSDGAGAVLLMKRSVADQKGI 1010
V I D+G+ + L KL+P FK+D G+ TAGN+S +SDGA A++L+ A + G+
Sbjct: 223 SVVIDKDEGLGKFDAAKLKKLRPSFKEDGGSVTAGNASSISDGAAALVLVSGEKALELGL 282
Query: 1011 PILGVFRSFVAVGVDPAIMXXXXXXXXXXXXXXXXLELDDIDLFEINEAFASQFVYCRNK 1190
++ R + P + L+ +D +EINEAF+ + +
Sbjct: 283 HVIAKIRGYADAAQAPELFTTTPALAIPKAIKRAGLDASQVDYYEINEAFSVVALANQKL 342
Query: 1191 LGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRYGVISMCIGTGMGAAA 1370
LGLDPE++N +GGA+++GHPLG +GAR + TLL + R K +YGV S+C G G +A
Sbjct: 343 LGLDPERLNAHGGAVSLGHPLGCSGARILVTLLGVL--RAKKGKYGVASICNGGGGASAL 400
Query: 1371 VFE 1379
V E
Sbjct: 401 VLE 403
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,041,410,375
Number of Sequences: 462764
Number of Extensions: 29041410375
Number of Successful Extensions: 295390318
Number of sequences better than 0.0: 0
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