BLASTX 7.6.2
Query= RU27669 /QuerySize=358
(357 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q1DR06|SET1_COCIM Histone-lysine N-methyltransferase, H3 lysi... 131 1e-030
sp|Q4WNH8|SET1_ASPFU Histone-lysine N-methyltransferase, H3 lysi... 130 2e-030
sp|Q2UMH3|SET1_ASPOR Histone-lysine N-methyltransferase, H3 lysi... 130 2e-030
sp|Q4I5R3|SET1_GIBZE Histone-lysine N-methyltransferase, H3 lysi... 129 3e-030
sp|Q6CEK8|SET1_YARLI Histone-lysine N-methyltransferase, H3 lysi... 128 7e-030
sp|Q08D57|SET1B_XENTR Histone-lysine N-methyltransferase SETD1B ... 128 9e-030
sp|Q1LY77|SE1BA_DANRE Histone-lysine N-methyltransferase SETD1B-... 127 1e-029
sp|Q5F3P8|SET1B_CHICK Histone-lysine N-methyltransferase SETD1B ... 127 1e-029
sp|Q9UPS6|SET1B_HUMAN Histone-lysine N-methyltransferase SETD1B ... 127 1e-029
sp|Q8CFT2|SET1B_MOUSE Histone-lysine N-methyltransferase SETD1B ... 127 1e-029
sp|Q66J90|SET1B_XENLA Histone-lysine N-methyltransferase SETD1B ... 127 1e-029
sp|Q2GWF3|SET1_CHAGB Histone-lysine N-methyltransferase, H3 lysi... 127 1e-029
sp|Q8X0S9|SET1_NEUCR Histone-lysine N-methyltransferase, H3 lysi... 127 1e-029
sp|O15047|SET1A_HUMAN Histone-lysine N-methyltransferase SETD1A ... 126 3e-029
sp|Q5B0Y5|SET1_EMENI Histone-lysine N-methyltransferase, H3 lysi... 126 3e-029
sp|Q6CIT4|SET1_KLULA Histone-lysine N-methyltransferase, H3 lysi... 125 6e-029
sp|Q6FKB1|SET1_CANGA Histone-lysine N-methyltransferase, H3 lysi... 124 1e-028
sp|Q75D88|SET1_ASHGO Histone-lysine N-methyltransferase, H3 lysi... 122 4e-028
sp|Q6BKL7|SET1_DEBHA Histone-lysine N-methyltransferase, H3 lysi... 122 4e-028
sp|Q5ABG1|SET1_CANAL Histone-lysine N-methyltransferase, H3 lysi... 122 7e-028
sp|Q9Y7R4|SET1_SCHPO Histone-lysine N-methyltransferase, H3 lysi... 120 3e-027
sp|Q18221|SET2_CAEEL Protein set-2 OS=Caenorhabditis elegans GN=... 118 7e-027
sp|P38827|SET1_YEAST Histone-lysine N-methyltransferase, H3 lysi... 118 1e-026
sp|Q4PB36|SET1_USTMA Histone-lysine N-methyltransferase, H3 lysi... 117 2e-026
sp|Q5KIA9|SET1_CRYNE Histone-lysine N-methyltransferase, H3 lysi... 107 1e-023
sp|Q24742|TRX_DROVI Histone-lysine N-methyltransferase trithorax... 87 2e-017
sp|P20659|TRX_DROME Histone-lysine N-methyltransferase trithorax... 86 5e-017
sp|Q84WW6|ASHH1_ARATH Histone-lysine N-methyltransferase ASHH1 O... 69 5e-012
sp|Q2LAE1|ASHH2_ARATH Histone-lysine N-methyltransferase ASHH2 O... 61 1e-009
sp|O14026|SET2_SCHPO Histone-lysine N-methyltransferase, H3 lysi... 57 2e-008
>sp|Q1DR06|SET1_COCIM Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Coccidioides immitis GN=SET1 PE=3 SV=1
Length = 1271
Score = 131 bits (327), Expect = 1e-030
Identities = 63/94 (67%), Positives = 75/94 (79%)
Frame = +2
Query: 74 ADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRERHY 253
+D+L+ QLK RKK +RF RS IH+WGL A E I A D +IEYVGE +R Q++D+RER Y
Sbjct: 1116 SDVLRFNQLKKRKKPVRFARSAIHNWGLYAEENISANDMIIEYVGEKVRQQVADMRERRY 1175
Query: 254 EKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
K GIGSSYLFRID+ V+DATKRGGIARFINHS
Sbjct: 1176 LKSGIGSSYLFRIDENTVIDATKRGGIARFINHS 1209
>sp|Q4WNH8|SET1_ASPFU Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Aspergillus fumigatus GN=set1 PE=3 SV=1
Length = 1241
Score = 130 bits (326), Expect = 2e-030
Identities = 63/93 (67%), Positives = 74/93 (79%)
Frame = +2
Query: 77 DLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRERHYE 256
D+L+ QLK RKK +RF RS IH+WGL A E I A D +IEYVGE +R Q++D+RER Y
Sbjct: 1087 DVLRFNQLKKRKKPVRFARSAIHNWGLYAEENISANDMIIEYVGEKVRQQVADMRERQYL 1146
Query: 257 KMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
K GIGSSYLFRID+ V+DATKRGGIARFINHS
Sbjct: 1147 KSGIGSSYLFRIDENTVIDATKRGGIARFINHS 1179
>sp|Q2UMH3|SET1_ASPOR Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Aspergillus oryzae GN=set1 PE=3 SV=1
Length = 1229
Score = 130 bits (326), Expect = 2e-030
Identities = 63/93 (67%), Positives = 74/93 (79%)
Frame = +2
Query: 77 DLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRERHYE 256
D+L+ QLK RKK +RF RS IH+WGL A E I A D +IEYVGE +R Q++D+RER Y
Sbjct: 1075 DVLRFNQLKKRKKPVRFARSAIHNWGLYAEENISANDMIIEYVGEKVRQQVADMRERQYL 1134
Query: 257 KMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
K GIGSSYLFRID+ V+DATKRGGIARFINHS
Sbjct: 1135 KSGIGSSYLFRIDENTVIDATKRGGIARFINHS 1167
>sp|Q4I5R3|SET1_GIBZE Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Gibberella zeae GN=SET1 PE=3 SV=1
Length = 1252
Score = 129 bits (324), Expect = 3e-030
Identities = 62/96 (64%), Positives = 75/96 (78%)
Frame = +2
Query: 68 EGADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRER 247
+ +D+ K QLK RKK ++F RS IH+WGL A+E I +D +IEYVGE +R QIS+IRE
Sbjct: 1106 QDSDVFKFNQLKKRKKPVKFARSAIHNWGLYAMENIAKDDMIIEYVGEQVRQQISEIREN 1165
Query: 248 HYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
Y K GIGSSYLFRIDD V+DATK+GGIARFINHS
Sbjct: 1166 RYLKSGIGSSYLFRIDDNTVIDATKKGGIARFINHS 1201
>sp|Q6CEK8|SET1_YARLI Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Yarrowia lipolytica GN=SET1 PE=3 SV=1
Length = 1170
Score = 128 bits (321), Expect = 7e-030
Identities = 61/105 (58%), Positives = 80/105 (76%), Gaps = 1/105 (0%)
Frame = +2
Query: 38 VKMRSLLAAAEGADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELI 217
+ M+ L + E D+L QL+ RKK ++F RS IH+WGL A+EPI A + +IEYVGE++
Sbjct: 1005 INMQKQLLSTE-TDVLNFNQLRKRKKPVKFARSAIHNWGLYAIEPIAANEMIIEYVGEVV 1063
Query: 218 RPQISDIRERHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINH 352
R +I+D+RE Y + GIGSSYLFR+D+ VVDATKRGGIARFINH
Sbjct: 1064 RQEIADLREARYMRSGIGSSYLFRVDESTVVDATKRGGIARFINH 1108
>sp|Q08D57|SET1B_XENTR Histone-lysine N-methyltransferase SETD1B OS=Xenopus
tropicalis GN=setd1b PE=2 SV=1
Length = 1956
Score = 128 bits (320), Expect = 9e-030
Identities = 65/110 (59%), Positives = 82/110 (74%), Gaps = 3/110 (2%)
Frame = +2
Query: 35 RVKMRSLLAAAEG---ADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYV 205
R + R LL++ G +DLLK QLK RKK+LRF +S IHDWGL A+EPI A++ VIEYV
Sbjct: 1788 RSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLRFCKSHIHDWGLFAMEPIIADEMVIEYV 1847
Query: 206 GELIRPQISDIRERHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
G+ IR I+D+RE+ YE GIGSSY+FR+D ++DATK G ARFINHS
Sbjct: 1848 GQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHS 1897
>sp|Q1LY77|SE1BA_DANRE Histone-lysine N-methyltransferase SETD1B-A OS=Danio
rerio GN=setd1ba PE=1 SV=2
Length = 1844
Score = 127 bits (319), Expect = 1e-029
Identities = 64/108 (59%), Positives = 81/108 (75%), Gaps = 1/108 (0%)
Frame = +2
Query: 35 RVKMRSLLAAAE-GADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGE 211
R + R LL++ +DLLK QLK RKK++RF RS IHDWGL A+EPI A++ VIEYVG+
Sbjct: 1678 RSEQRRLLSSFSCDSDLLKFNQLKFRKKKIRFCRSHIHDWGLFAMEPIAADEMVIEYVGQ 1737
Query: 212 LIRPQISDIRERHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
IR I+D+RE+ YE GIGSSY+FR+D ++DATK G ARFINHS
Sbjct: 1738 NIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHS 1785
>sp|Q5F3P8|SET1B_CHICK Histone-lysine N-methyltransferase SETD1B OS=Gallus
gallus GN=SETD1B PE=2 SV=1
Length = 2008
Score = 127 bits (319), Expect = 1e-029
Identities = 64/110 (58%), Positives = 82/110 (74%), Gaps = 3/110 (2%)
Frame = +2
Query: 35 RVKMRSLLAAAEG---ADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYV 205
R + R LL++ G +DLLK QLK RKK+L+F +S IHDWGL A+EPI A++ VIEYV
Sbjct: 1840 RSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYV 1899
Query: 206 GELIRPQISDIRERHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
G+ IR I+D+RE+ YE GIGSSY+FR+D ++DATK G ARFINHS
Sbjct: 1900 GQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHS 1949
>sp|Q9UPS6|SET1B_HUMAN Histone-lysine N-methyltransferase SETD1B OS=Homo sapiens
GN=SETD1B PE=1 SV=2
Length = 1923
Score = 127 bits (319), Expect = 1e-029
Identities = 64/110 (58%), Positives = 82/110 (74%), Gaps = 3/110 (2%)
Frame = +2
Query: 35 RVKMRSLLAAAEG---ADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYV 205
R + R LL++ G +DLLK QLK RKK+L+F +S IHDWGL A+EPI A++ VIEYV
Sbjct: 1755 RSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYV 1814
Query: 206 GELIRPQISDIRERHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
G+ IR I+D+RE+ YE GIGSSY+FR+D ++DATK G ARFINHS
Sbjct: 1815 GQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHS 1864
>sp|Q8CFT2|SET1B_MOUSE Histone-lysine N-methyltransferase SETD1B OS=Mus musculus
GN=Setd1b PE=2 SV=2
Length = 1985
Score = 127 bits (319), Expect = 1e-029
Identities = 64/110 (58%), Positives = 82/110 (74%), Gaps = 3/110 (2%)
Frame = +2
Query: 35 RVKMRSLLAAAEG---ADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYV 205
R + R LL++ G +DLLK QLK RKK+L+F +S IHDWGL A+EPI A++ VIEYV
Sbjct: 1817 RSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYV 1876
Query: 206 GELIRPQISDIRERHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
G+ IR I+D+RE+ YE GIGSSY+FR+D ++DATK G ARFINHS
Sbjct: 1877 GQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHS 1926
>sp|Q66J90|SET1B_XENLA Histone-lysine N-methyltransferase SETD1B OS=Xenopus
laevis GN=setd1b PE=2 SV=1
Length = 1938
Score = 127 bits (319), Expect = 1e-029
Identities = 64/110 (58%), Positives = 82/110 (74%), Gaps = 3/110 (2%)
Frame = +2
Query: 35 RVKMRSLLAAAEG---ADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYV 205
R + R LL++ G +DLLK QLK RKK++RF +S IHDWGL A+EPI A++ VIEYV
Sbjct: 1770 RSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKIRFCKSHIHDWGLFAMEPIVADEMVIEYV 1829
Query: 206 GELIRPQISDIRERHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
G+ IR I+D+RE+ YE GIGSSY+FR+D ++DATK G ARFINHS
Sbjct: 1830 GQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHS 1879
>sp|Q2GWF3|SET1_CHAGB Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Chaetomium globosum GN=SET1 PE=3 SV=1
Length = 1076
Score = 127 bits (319), Expect = 1e-029
Identities = 60/96 (62%), Positives = 76/96 (79%)
Frame = +2
Query: 68 EGADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRER 247
+ +D+L+ QLK RKK ++F RS IH+WGL A+E I +D +IEYVGE +R QI+++RE
Sbjct: 919 QDSDVLRFNQLKKRKKPVKFARSAIHNWGLYAMENIPKDDMIIEYVGEEVRQQIAELREN 978
Query: 248 HYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
Y K GIGSSYLFRIDD V+DATK+GGIARFINHS
Sbjct: 979 RYLKSGIGSSYLFRIDDNTVIDATKKGGIARFINHS 1014
>sp|Q8X0S9|SET1_NEUCR Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Neurospora crassa GN=set-1 PE=3 SV=1
Length = 1313
Score = 127 bits (319), Expect = 1e-029
Identities = 60/96 (62%), Positives = 76/96 (79%)
Frame = +2
Query: 68 EGADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRER 247
+ +D+L+ QLK RKK ++F RS IH+WGL A+E I +D +IEYVGE +R QI+++RE
Sbjct: 1156 QDSDVLRFNQLKKRKKPVKFARSAIHNWGLYAMENINKDDMIIEYVGEEVRQQIAELREA 1215
Query: 248 HYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
Y K GIGSSYLFRIDD V+DATK+GGIARFINHS
Sbjct: 1216 RYLKSGIGSSYLFRIDDNTVIDATKKGGIARFINHS 1251
>sp|O15047|SET1A_HUMAN Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens
GN=SETD1A PE=1 SV=3
Length = 1707
Score = 126 bits (316), Expect = 3e-029
Identities = 59/98 (60%), Positives = 77/98 (78%)
Frame = +2
Query: 59 AAAEGADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDI 238
+A +DLLK QLK RKK+LRF RS+IH+WGL A+EPI A++ VIEYVG+ IR ++D+
Sbjct: 1550 SAIMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADM 1609
Query: 239 RERHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINH 352
RE+ Y + GIGSSYLFR+D ++DATK G +ARFINH
Sbjct: 1610 REKRYVQEGIGSSYLFRVDHDTIIDATKCGNLARFINH 1647
>sp|Q5B0Y5|SET1_EMENI Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Emericella nidulans GN=set1 PE=3 SV=1
Length = 1220
Score = 126 bits (316), Expect = 3e-029
Identities = 61/94 (64%), Positives = 74/94 (78%)
Frame = +2
Query: 74 ADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRERHY 253
+D+L+ QLK RKK +RF RS IH+WGL A I A + +IEYVGE +R Q++D+RER Y
Sbjct: 1065 SDVLRFNQLKKRKKPVRFARSAIHNWGLYAEVNISANEMIIEYVGEKVRQQVADMRERRY 1124
Query: 254 EKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
K GIGSSYLFRID+ V+DATKRGGIARFINHS
Sbjct: 1125 LKSGIGSSYLFRIDENTVIDATKRGGIARFINHS 1158
>sp|Q6CIT4|SET1_KLULA Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Kluyveromyces lactis GN=SET1 PE=3 SV=1
Length = 1000
Score = 125 bits (313), Expect = 6e-029
Identities = 60/93 (64%), Positives = 73/93 (78%)
Frame = +2
Query: 74 ADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRERHY 253
+DLL QL RKK + F RS IH+WGL ALEPI A++ +IEYVGE IR ++++RE+ Y
Sbjct: 845 SDLLSLNQLTKRKKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRY 904
Query: 254 EKMGIGSSYLFRIDDGYVVDATKRGGIARFINH 352
K GIGSSYLFRID+ V+DATKRGGIARFINH
Sbjct: 905 IKSGIGSSYLFRIDENTVIDATKRGGIARFINH 937
>sp|Q6FKB1|SET1_CANGA Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Candida glabrata GN=SET1 PE=3 SV=1
Length = 1111
Score = 124 bits (310), Expect = 1e-028
Identities = 61/98 (62%), Positives = 74/98 (75%)
Frame = +2
Query: 59 AAAEGADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDI 238
A ++LL QL RKK + F RS IH+WGL ALEPI A++ VIEYVGE IR ++++
Sbjct: 951 ATGTESELLSLNQLNKRKKPVTFARSAIHNWGLYALEPINAKEMVIEYVGERIRQPVAEM 1010
Query: 239 RERHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINH 352
RER Y K GIGSSYLFRID+ V+DATK+GGIARFINH
Sbjct: 1011 RERRYIKNGIGSSYLFRIDEHTVIDATKKGGIARFINH 1048
>sp|Q75D88|SET1_ASHGO Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Ashbya gossypii GN=SET1 PE=3 SV=1
Length = 975
Score = 122 bits (306), Expect = 4e-028
Identities = 57/93 (61%), Positives = 73/93 (78%)
Frame = +2
Query: 74 ADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRERHY 253
++LL QL RKK + F RS IH+WGL ALEPI A++ +IEYVGE IR ++++RE+ Y
Sbjct: 820 SELLSLNQLTKRKKPVTFARSAIHNWGLYALEPISAKEMIIEYVGERIRQPVAEMREKRY 879
Query: 254 EKMGIGSSYLFRIDDGYVVDATKRGGIARFINH 352
K GIGSSYLFR+D+ V+DATK+GGIARFINH
Sbjct: 880 LKSGIGSSYLFRVDESTVIDATKKGGIARFINH 912
>sp|Q6BKL7|SET1_DEBHA Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Debaryomyces hansenii GN=SET1 PE=3 SV=2
Length = 1088
Score = 122 bits (306), Expect = 4e-028
Identities = 60/92 (65%), Positives = 71/92 (77%)
Frame = +2
Query: 77 DLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRERHYE 256
D+L L RKK + F RS IH+WGL ALEPI A++ +IEYVGE IR Q+++ RER Y
Sbjct: 934 DILNLNALTKRKKPVSFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQQVAEHRERSYL 993
Query: 257 KMGIGSSYLFRIDDGYVVDATKRGGIARFINH 352
K GIGSSYLFRID+ VVDATK+GGIARFINH
Sbjct: 994 KTGIGSSYLFRIDENTVVDATKKGGIARFINH 1025
>sp|Q5ABG1|SET1_CANAL Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Candida albicans GN=SET1 PE=3 SV=1
Length = 1040
Score = 122 bits (304), Expect = 7e-028
Identities = 58/93 (62%), Positives = 72/93 (77%)
Frame = +2
Query: 74 ADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRERHY 253
+D+L L RKK + F RS IH+WGL A+EPI A++ +IEYVGE IR Q+++ RE+ Y
Sbjct: 885 SDVLSLNALTKRKKPVTFARSAIHNWGLYAMEPIAAKEMIIEYVGERIRQQVAEHREKSY 944
Query: 254 EKMGIGSSYLFRIDDGYVVDATKRGGIARFINH 352
K GIGSSYLFRIDD V+DATK+GGIARFINH
Sbjct: 945 LKTGIGSSYLFRIDDNTVIDATKKGGIARFINH 977
>sp|Q9Y7R4|SET1_SCHPO Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Schizosaccharomyces pombe GN=set1 PE=1 SV=1
Length = 920
Score = 120 bits (299), Expect = 3e-027
Identities = 63/113 (55%), Positives = 79/113 (69%), Gaps = 6/113 (5%)
Frame = +2
Query: 35 RVKMRSLLAAAE------GADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVI 196
RV R L A E ADLL+ LKARKK+L F S+IH GL A+E I+ D VI
Sbjct: 749 RVNNRRLAAGVEKSQLPAEADLLRFNALKARKKQLHFGPSRIHTLGLFAMENIDKNDMVI 808
Query: 197 EYVGELIRPQISDIRERHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
EY+GE+IR +++D RE++Y + GIG SYLFRID+ +VDATK+G IARFINHS
Sbjct: 809 EYIGEIIRQRVADNREKNYVREGIGDSYLFRIDEDVIVDATKKGNIARFINHS 861
>sp|Q18221|SET2_CAEEL Protein set-2 OS=Caenorhabditis elegans GN=set-2 PE=2
SV=2
Length = 1507
Score = 118 bits (295), Expect = 7e-027
Identities = 59/115 (51%), Positives = 80/115 (69%), Gaps = 2/115 (1%)
Frame = +2
Query: 17 LSAITYRVKMRSLLAAAEGA--DLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDF 190
L++ R+ R LL + A D K QLK RKK ++F RS+IH WGL A+E I ++
Sbjct: 1334 LASKDMRLLQRRLLTSLGDANNDFFKINQLKFRKKMIKFARSRIHGWGLYAMESIAPDEM 1393
Query: 191 VIEYVGELIRPQISDIRERHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
++EY+G+ IR +++ RE+ YE+ GIGSSYLFRID +V+DATKRG ARFINHS
Sbjct: 1394 IVEYIGQTIRSLVAEEREKAYERRGIGSSYLFRIDLHHVIDATKRGNFARFINHS 1448
>sp|P38827|SET1_YEAST Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Saccharomyces cerevisiae GN=SET1 PE=1 SV=1
Length = 1080
Score = 118 bits (294), Expect = 1e-026
Identities = 55/93 (59%), Positives = 72/93 (77%)
Frame = +2
Query: 74 ADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRERHY 253
++LL QL RKK + F RS IH+WGL AL+ I A++ +IEYVGE IR ++++RE+ Y
Sbjct: 925 SELLSLNQLNKRKKPVMFARSAIHNWGLYALDSIAAKEMIIEYVGERIRQPVAEMREKRY 984
Query: 254 EKMGIGSSYLFRIDDGYVVDATKRGGIARFINH 352
K GIGSSYLFR+D+ V+DATK+GGIARFINH
Sbjct: 985 LKNGIGSSYLFRVDENTVIDATKKGGIARFINH 1017
>sp|Q4PB36|SET1_USTMA Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Ustilago maydis GN=SET1 PE=3 SV=1
Length = 1468
Score = 117 bits (292), Expect = 2e-026
Identities = 55/96 (57%), Positives = 71/96 (73%)
Frame = +2
Query: 65 AEGADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRE 244
A D+ K QL+ RKK+L+F +S IHDWGL A+E I A D VIEYVGE++R Q++D RE
Sbjct: 1311 ATDTDIFKFNQLRTRKKQLKFAKSPIHDWGLYAMELIPAGDMVIEYVGEVVRQQVADERE 1370
Query: 245 RHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINH 352
+ YE+ G S+YLFR+DD VVDAT +G IAR +NH
Sbjct: 1371 KQYERQGNFSTYLFRVDDDLVVDATHKGNIARLMNH 1406
>sp|Q5KIA9|SET1_CRYNE Histone-lysine N-methyltransferase, H3 lysine-4 specific
OS=Cryptococcus neoformans GN=SET1 PE=3 SV=1
Length = 1469
Score = 107 bits (267), Expect = 1e-023
Identities = 52/94 (55%), Positives = 68/94 (72%)
Frame = +2
Query: 74 ADLLKATQLKARKKRLRFQRSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRERHY 253
+DL QL+ RKK+LRF RS I +GL A+E I A + V EYVG+L+R ++D+RE+ Y
Sbjct: 1314 SDLFAFNQLRIRKKQLRFARSAIEGYGLYAMETIHAGEMVCEYVGDLVRATVADVREQRY 1373
Query: 254 EKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
K GIGSSYLFRID+ V DAT +G ++R INHS
Sbjct: 1374 LKQGIGSSYLFRIDNDIVCDATFKGSVSRLINHS 1407
>sp|Q24742|TRX_DROVI Histone-lysine N-methyltransferase trithorax OS=Drosophila
virilis GN=trx PE=3 SV=1
Length = 3828
Score = 87 bits (214), Expect = 2e-017
Identities = 45/75 (60%), Positives = 53/75 (70%), Gaps = 1/75 (1%)
Frame = +2
Query: 131 RSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRERHYEKMGIGSSYLFRIDDGYVV 310
RS IH GL + IEA + VIEY GELIR ++D RER+Y+ GIG Y+F+IDD VV
Sbjct: 3696 RSHIHGRGLYCTKDIEAGEMVIEYAGELIRSTLTDKRERYYDSRGIG-CYMFKIDDNLVV 3754
Query: 311 DATKRGGIARFINHS 355
DAT RG ARFINHS
Sbjct: 3755 DATMRGNAARFINHS 3769
>sp|P20659|TRX_DROME Histone-lysine N-methyltransferase trithorax OS=Drosophila
melanogaster GN=trx PE=1 SV=3
Length = 3726
Score = 86 bits (210), Expect = 5e-017
Identities = 44/74 (59%), Positives = 52/74 (70%), Gaps = 1/74 (1%)
Frame = +2
Query: 131 RSKIHDWGLIALEPIEAEDFVIEYVGELIRPQISDIRERHYEKMGIGSSYLFRIDDGYVV 310
RS IH GL + IEA + VIEY GELIR ++D RER+Y+ GIG Y+F+IDD VV
Sbjct: 3594 RSHIHGRGLYCTKDIEAGEMVIEYAGELIRSTLTDKRERYYDSRGIG-CYMFKIDDNLVV 3652
Query: 311 DATKRGGIARFINH 352
DAT RG ARFINH
Sbjct: 3653 DATMRGNAARFINH 3666
>sp|Q84WW6|ASHH1_ARATH Histone-lysine N-methyltransferase ASHH1 OS=Arabidopsis
thaliana GN=ASHH1 PE=2 SV=1
Length = 492
Score = 69 bits (167), Expect = 5e-012
Identities = 31/69 (44%), Positives = 47/69 (68%)
Frame = +2
Query: 149 WGLIALEPIEAEDFVIEYVGELIRPQISDIRERHYEKMGIGSSYLFRIDDGYVVDATKRG 328
WGL+ALE I+A F++EY GE+I + + R + YE G+ +Y+ ++ +DATK+G
Sbjct: 101 WGLVALEEIKAGQFIMEYCGEVISWKEAKKRAQTYETHGVKDAYIISLNASEAIDATKKG 160
Query: 329 GIARFINHS 355
+ARFINHS
Sbjct: 161 SLARFINHS 169
>sp|Q2LAE1|ASHH2_ARATH Histone-lysine N-methyltransferase ASHH2 OS=Arabidopsis
thaliana GN=ASHH2 PE=2 SV=1
Length = 1759
Score = 61 bits (147), Expect = 1e-009
Identities = 39/118 (33%), Positives = 56/118 (47%), Gaps = 3/118 (2%)
Frame = +2
Query: 8 GKGLSAITYRVKMRSLLAAAEGADLLKATQLKARK--KRLRFQRSKIHDWGLIALEPIEA 181
G G + + + L DL Q + RK K RFQ K +GL LE +
Sbjct: 990 GCGEECLNRMLNIECLQGTCPAGDLCSNQQFQKRKYVKFERFQSGK-KGYGLRLLEDVRE 1048
Query: 182 EDFVIEYVGELIRPQISDIRERHYEKMGIGSSYLFRIDDGYVVDATKRGGIARFINHS 355
F+IEYVGE++ Q + R++ Y G Y ++ V+DA +G + RFINHS
Sbjct: 1049 GQFLIEYVGEVLDMQSYETRQKEYAFKGQKHFYFMTLNGNEVIDAGAKGNLGRFINHS 1106
>sp|O14026|SET2_SCHPO Histone-lysine N-methyltransferase, H3 lysine-36 specific
OS=Schizosaccharomyces pombe GN=set2 PE=1 SV=1
Length = 798
Score = 57 bits (136), Expect = 2e-008
Identities = 30/69 (43%), Positives = 39/69 (56%)
Frame = +2
Query: 149 WGLIALEPIEAEDFVIEYVGELIRPQISDIRERHYEKMGIGSSYLFRIDDGYVVDATKRG 328
+GL A + + FV EY+GE+I Q R R Y+ GI Y + G +DATKRG
Sbjct: 192 FGLRADANLPKDTFVYEYIGEVIPEQKFRKRMRQYDSEGIKHFYFMMLQKGEYIDATKRG 251
Query: 329 GIARFINHS 355
+ARF NHS
Sbjct: 252 SLARFCNHS 260
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,987,770,860
Number of Sequences: 462764
Number of Extensions: 30987770860
Number of Successful Extensions: 304546666
Number of sequences better than 0.0: 0
|