BLASTX 7.6.2 Query= RU36285 /QuerySize=225 (224 letters) Database: UniProt/Swiss-Prot; 462,764 sequences; 163,773,382 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q68DV7|RNF43_HUMAN RING finger protein 43 OS=Homo sapiens GN=... 66 5e-011 sp|Q5NCP0|RNF43_MOUSE RING finger protein 43 OS=Mus musculus GN=... 65 9e-011 sp|Q6NRX0|RN149_XENLA E3 ubiquitin-protein ligase RNF149 OS=Xeno... 64 2e-010 sp|Q9WTV7|RNF12_MOUSE E3 ubiquitin-protein ligase RNF12 OS=Mus m... 64 2e-010 sp|Q86XS8|GOLI_HUMAN Goliath homolog OS=Homo sapiens GN=RNF130 P... 63 3e-010 sp|Q8VEM1|GOLI_MOUSE Goliath homolog OS=Mus musculus GN=Rnf130 P... 63 3e-010 sp|Q6Y290|GOLI_RAT Goliath homolog OS=Rattus norvegicus GN=Rnf13... 63 3e-010 sp|Q8NC42|RN149_HUMAN E3 ubiquitin-protein ligase RNF149 OS=Homo... 63 3e-010 sp|Q9Y6U7|RN215_HUMAN RING finger protein 215 OS=Homo sapiens GN... 63 3e-010 sp|Q5SPX3|RN215_MOUSE RING finger protein 215 OS=Mus musculus GN... 63 3e-010 sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 63 4e-010 sp|Q9Y252|RNF6_HUMAN RING finger protein 6 OS=Homo sapiens GN=RN... 63 4e-010 sp|Q9ULT6|ZNRF3_HUMAN Zinc/RING finger protein 3 OS=Homo sapiens... 63 4e-010 sp|Q5SSZ7|ZNRF3_MOUSE Zinc/RING finger protein 3 OS=Mus musculus... 63 4e-010 sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 62 6e-010 sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 62 6e-010 sp|Q06003|GOLI_DROME Protein goliath OS=Drosophila melanogaster ... 62 7e-010 sp|Q9NVW2|RNF12_HUMAN E3 ubiquitin-protein ligase RNF12 OS=Homo ... 62 7e-010 sp|Q07G42|RNF12_XENTR E3 ubiquitin-protein ligase rnf12 OS=Xenop... 62 7e-010 sp|Q641J8|RF12A_XENLA E3 ubiquitin-protein ligase rnf12-A OS=Xen... 62 1e-009 sp|Q7T037|RF12B_XENLA E3 ubiquitin-protein ligase rnf12-B OS=Xen... 62 1e-009 sp|Q9ULK6|RN150_HUMAN RING finger protein 150 OS=Homo sapiens GN... 62 1e-009 sp|Q5DTZ6|RN150_MOUSE RING finger protein 150 OS=Mus musculus GN... 62 1e-009 sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN... 61 1e-009 sp|Q3U2C5|RN149_MOUSE E3 ubiquitin-protein ligase RNF149 OS=Mus ... 61 2e-009 sp|Q8WVZ7|RN133_HUMAN RING finger protein 133 OS=Homo sapiens GN... 60 4e-009 sp|Q95K04|RN133_MACFA RING finger protein 133 OS=Macaca fascicul... 60 4e-009 sp|Q9Y4L5|RN115_HUMAN RING finger protein 115 OS=Homo sapiens GN... 59 5e-009 sp|Q29RU0|RN128_BOVIN E3 ubiquitin-protein ligase RNF128 OS=Bos ... 59 5e-009 sp|Q566M8|RN150_DANRE RING finger protein 150 OS=Danio rerio GN=... 59 5e-009 >sp|Q68DV7|RNF43_HUMAN RING finger protein 43 OS=Homo sapiens GN=RNF43 PE=1 SV=1 Length = 783 Score = 66 bits (159), Expect = 5e-011 Identities = 22/48 (45%), Positives = 34/48 (70%) Frame = +2 Query: 14 CSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCKYRAGSG 157 C++CLE+ + G+ +R + CLH+FH +C+DPWL Q TCP+C + G Sbjct: 272 CAICLEEFSEGQELRVISCLHEFHRNCVDPWLHQHRTCPLCMFNITEG 319 >sp|Q5NCP0|RNF43_MOUSE RING finger protein 43 OS=Mus musculus GN=Rnf43 PE=2 SV=1 Length = 784 Score = 65 bits (157), Expect = 9e-011 Identities = 26/62 (41%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Frame = +2 Query: 14 CSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCKYRAGSGWHENGQGAAMDA 193 C++CLE+ + G+ +R + CLH+FH +C+DPWL Q TCP+C + G Q A Sbjct: 272 CAICLEEFSEGQELRVISCLHEFHRTCVDPWLYQHRTCPLCMFNIVEG-DSFSQAPAASP 330 Query: 194 SY 199 SY Sbjct: 331 SY 332 >sp|Q6NRX0|RN149_XENLA E3 ubiquitin-protein ligase RNF149 OS=Xenopus laevis GN=rnf149 PE=2 SV=1 Length = 397 Score = 64 bits (154), Expect = 2e-010 Identities = 25/46 (54%), Positives = 31/46 (67%) Frame = +2 Query: 2 DELTCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 D C+VC+E T +L+R LPC H FH CIDPWL + TCP+CK Sbjct: 260 DAENCAVCIENYKTKDLVRILPCKHIFHRLCIDPWLIEHRTCPMCK 305 >sp|Q9WTV7|RNF12_MOUSE E3 ubiquitin-protein ligase RNF12 OS=Mus musculus GN=Rnf12 PE=1 SV=1 Length = 600 Score = 64 bits (154), Expect = 2e-010 Identities = 22/43 (51%), Positives = 30/43 (69%) Frame = +2 Query: 11 TCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 TCSVC+ + G+ +R LPC H+FH CID WL + TCP+C+ Sbjct: 545 TCSVCITEYTEGDKLRKLPCSHEFHVHCIDRWLSENSTCPICR 587 >sp|Q86XS8|GOLI_HUMAN Goliath homolog OS=Homo sapiens GN=RNF130 PE=2 SV=1 Length = 419 Score = 63 bits (152), Expect = 3e-010 Identities = 22/42 (52%), Positives = 30/42 (71%) Frame = +2 Query: 14 CSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 C+VC+E +++R LPC H FH SC+DPWL + TCP+CK Sbjct: 264 CAVCIESYKQNDVVRILPCKHVFHKSCVDPWLSEHCTCPMCK 305 >sp|Q8VEM1|GOLI_MOUSE Goliath homolog OS=Mus musculus GN=Rnf130 PE=2 SV=1 Length = 419 Score = 63 bits (152), Expect = 3e-010 Identities = 22/42 (52%), Positives = 30/42 (71%) Frame = +2 Query: 14 CSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 C+VC+E +++R LPC H FH SC+DPWL + TCP+CK Sbjct: 264 CAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCK 305 >sp|Q6Y290|GOLI_RAT Goliath homolog OS=Rattus norvegicus GN=Rnf130 PE=1 SV=1 Length = 419 Score = 63 bits (152), Expect = 3e-010 Identities = 22/42 (52%), Positives = 30/42 (71%) Frame = +2 Query: 14 CSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 C+VC+E +++R LPC H FH SC+DPWL + TCP+CK Sbjct: 264 CAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCK 305 >sp|Q8NC42|RN149_HUMAN E3 ubiquitin-protein ligase RNF149 OS=Homo sapiens GN=RNF149 PE=2 SV=2 Length = 400 Score = 63 bits (152), Expect = 3e-010 Identities = 30/67 (44%), Positives = 36/67 (53%), Gaps = 3/67 (4%) Frame = +2 Query: 2 DELTCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK---YRAGSGWHENG 172 D C+VC+E ++IR LPC H FH CIDPWL TCP+CK +A W E G Sbjct: 265 DAENCAVCIENFKVKDIIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGEPG 324 Query: 173 QGAAMDA 193 M A Sbjct: 325 DVQEMPA 331 >sp|Q9Y6U7|RN215_HUMAN RING finger protein 215 OS=Homo sapiens GN=RNF215 PE=1 SV=2 Length = 377 Score = 63 bits (152), Expect = 3e-010 Identities = 23/44 (52%), Positives = 31/44 (70%) Frame = +2 Query: 11 TCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCKY 142 TC+VCL+ + +R LPC H+FH C+DPWL Q TCP+CK+ Sbjct: 324 TCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKF 367 >sp|Q5SPX3|RN215_MOUSE RING finger protein 215 OS=Mus musculus GN=Rnf215 PE=2 SV=1 Length = 379 Score = 63 bits (152), Expect = 3e-010 Identities = 23/44 (52%), Positives = 31/44 (70%) Frame = +2 Query: 11 TCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCKY 142 TC+VCL+ + +R LPC H+FH C+DPWL Q TCP+CK+ Sbjct: 326 TCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKF 369 >sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-A PE=2 SV=1 Length = 312 Score = 63 bits (151), Expect = 4e-010 Identities = 25/44 (56%), Positives = 27/44 (61%) Frame = +2 Query: 8 LTCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 L C VC E GE +R LPC H FH CI PWL Q TCPVC+ Sbjct: 226 LECPVCKEDYTVGECVRQLPCNHLFHNDCIIPWLEQHDTCPVCR 269 >sp|Q9Y252|RNF6_HUMAN RING finger protein 6 OS=Homo sapiens GN=RNF6 PE=2 SV=1 Length = 685 Score = 63 bits (151), Expect = 4e-010 Identities = 26/54 (48%), Positives = 33/54 (61%), Gaps = 1/54 (1%) Frame = +2 Query: 14 CSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCKYRA-GSGWHENG 172 CSVC+ TG +R LPC+H+FH CID WL + TCP+C+ GS NG Sbjct: 632 CSVCISDYVTGNKLRQLPCMHEFHIHCIDRWLSENCTCPICRQPVLGSNIANNG 685 >sp|Q9ULT6|ZNRF3_HUMAN Zinc/RING finger protein 3 OS=Homo sapiens GN=ZNRF3 PE=2 SV=3 Length = 936 Score = 63 bits (151), Expect = 4e-010 Identities = 22/43 (51%), Positives = 31/43 (72%) Frame = +2 Query: 14 CSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCKY 142 C++CLE+ GE +R +PC H+FH C+DPWL Q TCP C++ Sbjct: 293 CAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRH 335 >sp|Q5SSZ7|ZNRF3_MOUSE Zinc/RING finger protein 3 OS=Mus musculus GN=Znrf3 PE=2 SV=1 Length = 913 Score = 63 bits (151), Expect = 4e-010 Identities = 22/43 (51%), Positives = 31/43 (72%) Frame = +2 Query: 14 CSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCKY 142 C++CLE+ GE +R +PC H+FH C+DPWL Q TCP C++ Sbjct: 290 CAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRH 332 >sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-B PE=2 SV=1 Length = 312 Score = 62 bits (150), Expect = 6e-010 Identities = 25/44 (56%), Positives = 27/44 (61%) Frame = +2 Query: 8 LTCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 L C VC E GE +R LPC H FH CI PWL Q TCPVC+ Sbjct: 226 LECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCR 269 >sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126 PE=2 SV=1 Length = 311 Score = 62 bits (150), Expect = 6e-010 Identities = 25/44 (56%), Positives = 27/44 (61%) Frame = +2 Query: 8 LTCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 L C VC E GE +R LPC H FH CI PWL Q TCPVC+ Sbjct: 225 LECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCR 268 >sp|Q06003|GOLI_DROME Protein goliath OS=Drosophila melanogaster GN=gol PE=2 SV=3 Length = 461 Score = 62 bits (149), Expect = 7e-010 Identities = 23/46 (50%), Positives = 31/46 (67%) Frame = +2 Query: 2 DELTCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 D C++C+E + IR LPC H+FH +CIDPWL + TCP+CK Sbjct: 299 DSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCK 344 >sp|Q9NVW2|RNF12_HUMAN E3 ubiquitin-protein ligase RNF12 OS=Homo sapiens GN=RNF12 PE=2 SV=3 Length = 624 Score = 62 bits (149), Expect = 7e-010 Identities = 21/43 (48%), Positives = 29/43 (67%) Frame = +2 Query: 11 TCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 TCSVC+ + G +R LPC H++H CID WL + TCP+C+ Sbjct: 569 TCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICR 611 >sp|Q07G42|RNF12_XENTR E3 ubiquitin-protein ligase rnf12 OS=Xenopus tropicalis GN=rnf12 PE=2 SV=1 Length = 639 Score = 62 bits (149), Expect = 7e-010 Identities = 21/43 (48%), Positives = 29/43 (67%) Frame = +2 Query: 11 TCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 TCSVC+ + G +R LPC H++H CID WL + TCP+C+ Sbjct: 584 TCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICR 626 >sp|Q641J8|RF12A_XENLA E3 ubiquitin-protein ligase rnf12-A OS=Xenopus laevis GN=rnf12-A PE=1 SV=1 Length = 622 Score = 62 bits (148), Expect = 1e-009 Identities = 21/43 (48%), Positives = 29/43 (67%) Frame = +2 Query: 11 TCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 TCSVC+ + G +R LPC H++H CID WL + TCP+C+ Sbjct: 567 TCSVCITEYTEGNKLRKLPCSHEYHIHCIDRWLSENSTCPICR 609 >sp|Q7T037|RF12B_XENLA E3 ubiquitin-protein ligase rnf12-B OS=Xenopus laevis GN=rnf12-B PE=2 SV=1 Length = 757 Score = 62 bits (148), Expect = 1e-009 Identities = 21/43 (48%), Positives = 29/43 (67%) Frame = +2 Query: 11 TCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 TCSVC+ + G +R LPC H++H CID WL + TCP+C+ Sbjct: 702 TCSVCITEYTEGNKLRKLPCSHEYHIHCIDRWLSENSTCPICR 744 >sp|Q9ULK6|RN150_HUMAN RING finger protein 150 OS=Homo sapiens GN=RNF150 PE=2 SV=2 Length = 438 Score = 62 bits (148), Expect = 1e-009 Identities = 22/42 (52%), Positives = 29/42 (69%) Frame = +2 Query: 14 CSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 C+VC+E +++R LPC H FH SC+DPWL TCP+CK Sbjct: 278 CAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCK 319 >sp|Q5DTZ6|RN150_MOUSE RING finger protein 150 OS=Mus musculus GN=Rnf150 PE=2 SV=2 Length = 437 Score = 62 bits (148), Expect = 1e-009 Identities = 22/42 (52%), Positives = 29/42 (69%) Frame = +2 Query: 14 CSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 C+VC+E +++R LPC H FH SC+DPWL TCP+CK Sbjct: 277 CAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCK 318 >sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN=Rnf126 PE=1 SV=1 Length = 313 Score = 61 bits (147), Expect = 1e-009 Identities = 25/44 (56%), Positives = 28/44 (63%) Frame = +2 Query: 8 LTCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 L C VC E GE +R LPC H FH SCI PWL Q +CPVC+ Sbjct: 229 LECPVCKEDYALGESVRQLPCNHLFHDSCIVPWLEQHDSCPVCR 272 >sp|Q3U2C5|RN149_MOUSE E3 ubiquitin-protein ligase RNF149 OS=Mus musculus GN=Rnf149 PE=2 SV=2 Length = 394 Score = 61 bits (146), Expect = 2e-009 Identities = 24/46 (52%), Positives = 29/46 (63%) Frame = +2 Query: 2 DELTCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 D C+VC+E ++IR LPC H FH CIDPWL TCP+CK Sbjct: 261 DAENCAVCIENFKVKDVIRILPCKHIFHRICIDPWLLDHRTCPMCK 306 >sp|Q8WVZ7|RN133_HUMAN RING finger protein 133 OS=Homo sapiens GN=RNF133 PE=2 SV=1 Length = 376 Score = 60 bits (143), Expect = 4e-009 Identities = 20/43 (46%), Positives = 29/43 (67%) Frame = +2 Query: 11 TCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 +C +C E+ +++R L C H FH +CIDPW+ GTCP+CK Sbjct: 255 SCVICFERYKPNDIVRILTCKHFFHKNCIDPWILPHGTCPICK 297 >sp|Q95K04|RN133_MACFA RING finger protein 133 OS=Macaca fascicularis GN=RNF133 PE=2 SV=1 Length = 376 Score = 60 bits (143), Expect = 4e-009 Identities = 20/43 (46%), Positives = 28/43 (65%) Frame = +2 Query: 11 TCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 +C +C E +++R L C H FH +CIDPW+ GTCP+CK Sbjct: 255 SCVICFEHYKPNDIVRILTCKHFFHKNCIDPWILSHGTCPICK 297 >sp|Q9Y4L5|RN115_HUMAN RING finger protein 115 OS=Homo sapiens GN=RNF115 PE=2 SV=2 Length = 304 Score = 59 bits (142), Expect = 5e-009 Identities = 28/63 (44%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Frame = +2 Query: 8 LTCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCKYRAGSGWHENGQGAAM 187 L C VC E E +R LPC H FH+SCI PWL TCPVC+ ++ +G Q + Sbjct: 226 LECPVCKEDYTVEEEVRQLPCNHFFHSSCIVPWLELHDTCPVCR-KSLNGEDSTRQSQST 284 Query: 188 DAS 196 +AS Sbjct: 285 EAS 287 >sp|Q29RU0|RN128_BOVIN E3 ubiquitin-protein ligase RNF128 OS=Bos taurus GN=RNF128 PE=2 SV=1 Length = 431 Score = 59 bits (142), Expect = 5e-009 Identities = 21/43 (48%), Positives = 30/43 (69%) Frame = +2 Query: 11 TCSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 +C+VC+E +L+R L C H FH +C+DPWL + TCP+CK Sbjct: 279 SCAVCIELYKPNDLVRILTCNHVFHKTCVDPWLLEHRTCPMCK 321 >sp|Q566M8|RN150_DANRE RING finger protein 150 OS=Danio rerio GN=rnf150 PE=2 SV=1 Length = 419 Score = 59 bits (142), Expect = 5e-009 Identities = 21/42 (50%), Positives = 28/42 (66%) Frame = +2 Query: 14 CSVCLEQVNTGELIRSLPCLHQFHASCIDPWLRQQGTCPVCK 139 C+VC+E +++R LPC H FH C+DPWL TCP+CK Sbjct: 267 CAVCIEGYKPNDVVRILPCRHLFHKCCVDPWLVDHRTCPMCK 308 Database: UniProt/Swiss-Prot Posted date: Thu Apr 23 14:22:33 2009 Number of letters in database: 163,773,382 Number of sequences in database: 462,764 Lambda K H 0.267 0.041 0.140 Gapped Lambda K H 0.267 0.041 0.140 Matrix: blosum62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 35,439,239,412 Number of Sequences: 462764 Number of Extensions: 35439239412 Number of Successful Extensions: 339312642 Number of sequences better than 0.0: 0 |