BLASTX 7.6.2
Query= RU44963 /QuerySize=450
(449 letters)
Database: UniProt/Swiss-Prot;
462,764 sequences; 163,773,382 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7LBC6|JHD2B_HUMAN JmjC domain-containing histone demethylati... 104 2e-022
sp|Q6ZPY7|JHD2B_MOUSE JmjC domain-containing histone demethylati... 104 2e-022
sp|Q63679|JHD2A_RAT JmjC domain-containing histone demethylation... 100 5e-021
sp|Q9Y4C1|JHD2A_HUMAN JmjC domain-containing histone demethylati... 99 8e-021
sp|Q6PCM1|JHD2A_MOUSE JmjC domain-containing histone demethylati... 99 8e-021
sp|Q6IRB8|JD2AA_XENLA JmjC domain-containing histone demethylati... 98 1e-020
sp|Q5HZN1|JD2AB_XENLA JmjC domain-containing histone demethylati... 98 1e-020
sp|Q5ZIX8|JHD2A_CHICK JmjC domain-containing histone demethylati... 97 2e-020
sp|Q15652|JHD2C_HUMAN Probable JmjC domain-containing histone de... 70 3e-012
sp|Q69ZK6|JHD2C_MOUSE Probable JmjC domain-containing histone de... 69 7e-012
sp|P97609|HAIR_RAT Protein hairless OS=Rattus norvegicus GN=Hr P... 55 2e-007
sp|Q61645|HAIR_MOUSE Protein hairless OS=Mus musculus GN=Hr PE=2... 54 2e-007
sp|O43593|HAIR_HUMAN Protein hairless OS=Homo sapiens GN=HR PE=1... 49 7e-006
>sp|Q7LBC6|JHD2B_HUMAN JmjC domain-containing histone demethylation protein 2B
OS=Homo sapiens GN=JMJD1B PE=1 SV=1
Length = 1761
Score = 104 bits (258), Expect = 2e-022
Identities = 50/83 (60%), Positives = 59/83 (71%)
Frame = +2
Query: 8 WTFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRAR 187
W VQ LG+AVFIPAG PHQV NL SC KVA DFVSPE+V C RLT++FR L H
Sbjct: 1671 WAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEFRHLSNTHTNH 1730
Query: 188 EDKLEIKKMILYAVDQAVKDLEA 256
EDKL++K +I +AV AV L+A
Sbjct: 1731 EDKLQVKNIIYHAVKDAVGTLKA 1753
>sp|Q6ZPY7|JHD2B_MOUSE JmjC domain-containing histone demethylation protein 2B
OS=Mus musculus GN=Jmjd1b PE=2 SV=2
Length = 1562
Score = 104 bits (258), Expect = 2e-022
Identities = 50/83 (60%), Positives = 59/83 (71%)
Frame = +2
Query: 8 WTFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRAR 187
W VQ LG+AVFIPAG PHQV NL SC KVA DFVSPE+V C RLT++FR L H
Sbjct: 1472 WAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEFRHLSNTHTNH 1531
Query: 188 EDKLEIKKMILYAVDQAVKDLEA 256
EDKL++K +I +AV AV L+A
Sbjct: 1532 EDKLQVKNIIYHAVKDAVGTLKA 1554
>sp|Q63679|JHD2A_RAT JmjC domain-containing histone demethylation protein 2A
OS=Rattus norvegicus GN=Jmjd1a PE=2 SV=1
Length = 1214
Score = 100 bits (247), Expect = 5e-021
Identities = 48/84 (57%), Positives = 59/84 (70%)
Frame = +2
Query: 8 WTFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRAR 187
W VQ LG+ VFIPAG PHQV NL SC KVA DFVSPE+V C LT++FR L + H
Sbjct: 1117 WAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRHLSQTHTNH 1176
Query: 188 EDKLEIKKMILYAVDQAVKDLEAL 259
EDKL++K +I +AV AV L+A+
Sbjct: 1177 EDKLQVKNVIYHAVKDAVAMLKAV 1200
>sp|Q9Y4C1|JHD2A_HUMAN JmjC domain-containing histone demethylation protein 2A
OS=Homo sapiens GN=JMJD1A PE=1 SV=3
Length = 1321
Score = 99 bits (245), Expect = 8e-021
Identities = 48/83 (57%), Positives = 58/83 (69%)
Frame = +2
Query: 8 WTFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRAR 187
W VQ LG+ VFIPAG PHQV NL SC KVA DFVSPE+V C LT++FR L + H
Sbjct: 1231 WAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSQTHTNH 1290
Query: 188 EDKLEIKKMILYAVDQAVKDLEA 256
EDKL++K +I +AV AV L+A
Sbjct: 1291 EDKLQVKNVIYHAVKDAVAMLKA 1313
>sp|Q6PCM1|JHD2A_MOUSE JmjC domain-containing histone demethylation protein 2A
OS=Mus musculus GN=Jmjd1a PE=2 SV=1
Length = 1323
Score = 99 bits (245), Expect = 8e-021
Identities = 48/83 (57%), Positives = 58/83 (69%)
Frame = +2
Query: 8 WTFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRAR 187
W VQ LG+ VFIPAG PHQV NL SC KVA DFVSPE+V C LT++FR L + H
Sbjct: 1233 WAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSQTHTNH 1292
Query: 188 EDKLEIKKMILYAVDQAVKDLEA 256
EDKL++K +I +AV AV L+A
Sbjct: 1293 EDKLQVKNVIYHAVKDAVAMLKA 1315
>sp|Q6IRB8|JD2AA_XENLA JmjC domain-containing histone demethylation protein 2A-A
OS=Xenopus laevis GN=jmjd1a-A PE=2 SV=1
Length = 1331
Score = 98 bits (243), Expect = 1e-020
Identities = 47/83 (56%), Positives = 58/83 (69%)
Frame = +2
Query: 8 WTFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRAR 187
W VQ LG+AVFIPAG PHQV NL SC KVA DFVSPE+V C LT++FR L H
Sbjct: 1241 WAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSHTHTNH 1300
Query: 188 EDKLEIKKMILYAVDQAVKDLEA 256
EDKL++K +I +AV ++ L+A
Sbjct: 1301 EDKLQVKNVIYHAVKDSIAILKA 1323
>sp|Q5HZN1|JD2AB_XENLA JmjC domain-containing histone demethylation protein 2A-B
OS=Xenopus laevis GN=jmjd1a-B PE=2 SV=1
Length = 1334
Score = 98 bits (243), Expect = 1e-020
Identities = 47/83 (56%), Positives = 58/83 (69%)
Frame = +2
Query: 8 WTFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRAR 187
W VQ LG+AVFIPAG PHQV NL SC KVA DFVSPE+V C LT++FR L H
Sbjct: 1244 WAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFCLTQEFRYLSHTHTNH 1303
Query: 188 EDKLEIKKMILYAVDQAVKDLEA 256
EDKL++K +I +AV ++ L+A
Sbjct: 1304 EDKLQVKNVIYHAVKDSIAILKA 1326
>sp|Q5ZIX8|JHD2A_CHICK JmjC domain-containing histone demethylation protein 2A
OS=Gallus gallus GN=JMJD1A PE=2 SV=1
Length = 1325
Score = 97 bits (241), Expect = 2e-020
Identities = 48/83 (57%), Positives = 56/83 (67%)
Frame = +2
Query: 8 WTFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRAR 187
W VQ LG+ VFIPAG PHQV NL SC KVA DFVSPE+V C LT++FR L H
Sbjct: 1235 WAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSHTHTNH 1294
Query: 188 EDKLEIKKMILYAVDQAVKDLEA 256
EDKL++K +I +AV AV L A
Sbjct: 1295 EDKLQVKNVIYHAVKDAVGILRA 1317
>sp|Q15652|JHD2C_HUMAN Probable JmjC domain-containing histone demethylation
protein 2C OS=Homo sapiens GN=JMJD1C PE=1 SV=2
Length = 2540
Score = 70 bits (171), Expect = 3e-012
Identities = 35/81 (43%), Positives = 54/81 (66%), Gaps = 1/81 (1%)
Frame = +2
Query: 11 TFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRARE 190
T +Q LG+A+ +PAG HQV+N SC +V DFVSPE++ E LT++ R L K +
Sbjct: 2449 TLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRLL-KEEINYD 2507
Query: 191 DKLEIKKMILYAVDQAVKDLE 253
DKL++K ++ +AV + V+ L+
Sbjct: 2508 DKLQVKNILYHAVKEMVRALK 2528
>sp|Q69ZK6|JHD2C_MOUSE Probable JmjC domain-containing histone demethylation
protein 2C OS=Mus musculus GN=Jmjd1c PE=1 SV=2
Length = 2350
Score = 69 bits (168), Expect = 7e-012
Identities = 34/81 (41%), Positives = 54/81 (66%), Gaps = 1/81 (1%)
Frame = +2
Query: 11 TFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRARE 190
T +Q LG+A+ +PAG HQV+N SC +V DFVSPE++ + LT++ R L K +
Sbjct: 2259 TLIQFLGDAIVLPAGTLHQVQNFHSCVQVTEDFVSPEHLVQSFHLTQELRLL-KEEINYD 2317
Query: 191 DKLEIKKMILYAVDQAVKDLE 253
DKL++K ++ +AV + V+ L+
Sbjct: 2318 DKLQVKNILYHAVKEMVRALK 2338
>sp|P97609|HAIR_RAT Protein hairless OS=Rattus norvegicus GN=Hr PE=2 SV=2
Length = 1181
Score = 55 bits (130), Expect = 2e-007
Identities = 31/82 (37%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Frame = +2
Query: 8 WTFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRAR 187
WT +Q+ GEAV +PAG PHQV+ L S V F+SPE +L LP +HR
Sbjct: 1099 WTLLQAPGEAVLVPAGAPHQVQGLVSTISVTQHFLSPETSALSAQLCHQGASLPPDHRML 1158
Query: 188 EDKLEIKKMILYAVDQAVKDLE 253
+++ + + AV AV L+
Sbjct: 1159 YAQMD--RAVFQAVKVAVGTLQ 1178
>sp|Q61645|HAIR_MOUSE Protein hairless OS=Mus musculus GN=Hr PE=2 SV=2
Length = 1182
Score = 54 bits (129), Expect = 2e-007
Identities = 31/82 (37%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Frame = +2
Query: 8 WTFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRAR 187
WT +Q+ GEAV +PAG PHQV+ L S V F+SPE +L LP +HR
Sbjct: 1100 WTLLQAPGEAVLVPAGAPHQVQGLVSTISVTQHFLSPETSALSAQLYHQGASLPPDHRML 1159
Query: 188 EDKLEIKKMILYAVDQAVKDLE 253
+++ + + AV AV L+
Sbjct: 1160 YAQMD--RAVFQAVKAAVGALQ 1179
>sp|O43593|HAIR_HUMAN Protein hairless OS=Homo sapiens GN=HR PE=1 SV=5
Length = 1189
Score = 49 bits (116), Expect = 7e-006
Identities = 30/79 (37%), Positives = 41/79 (51%), Gaps = 6/79 (7%)
Frame = +2
Query: 8 WTFVQSLGEAVFIPAGCPHQVRNLKSCTKVAVDFVSPENVHECLRLTKDFRQLPKNHRAR 187
WT +Q+ GEAV +PAG PHQV+ L S V F+SPE +L LP +
Sbjct: 1107 WTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHFLSPETSALSAQLCHQGPSLPPDCHLL 1166
Query: 188 EDKLEIKKMILYAVDQAVK 244
+++ +AV QAVK
Sbjct: 1167 YAQMD------WAVFQAVK 1179
Database: UniProt/Swiss-Prot
Posted date: Thu Apr 23 14:22:33 2009
Number of letters in database: 163,773,382
Number of sequences in database: 462,764
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,621,414,376
Number of Sequences: 462764
Number of Extensions: 39621414376
Number of Successful Extensions: 367225502
Number of sequences better than 0.0: 0
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